Search filters

List of works by Alexander Bürkle

A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks

scientific article published on 23 April 2009

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study

scientific article

Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study

scientific article published on 29 August 2016

Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study

scientific article published on 30 April 2018

Association of Torquetenovirus Viremia with Physical Frailty and Cognitive Impairment in Three Independent European Cohorts

scientific article published in 2023

Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents

scientific journal article

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project

scientific article published on 19 July 2017

Cardiorespiratory and Neuromuscular Demand of Daily Centrifugation: Results From the 60-Day AGBRESA Bed Rest Study

scientific article published on 11 September 2020

DNA hydroxymethylation levels are altered in blood cells from Down syndrome persons enrolled in the MARK-AGE project

scientific article published on 21 October 2017

Gender- and age-dependencies of oxidative stress, as detected based on the steady state concentrations of different biomarkers in the MARK-AGE study

scientific article published on 15 April 2019

High-resolution quantitative metabolome analysis of urine by automated flow injection NMR.

scientific article published on 29 May 2013

Impaired PARP activity in response to the β-adrenergic receptor agonist isoproterenol

scientific article published on 10 February 2018

Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1.

scientific article published on 8 June 2010

Influence of Acute Exercise on DNA Repair and PARP Activity before and after Irradiation in Lymphocytes from Trained and Untrained Individuals

scientific article published on 19 June 2019

Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells.

scientific article published on 9 October 2012

MARK-AGE biomarkers of ageing

scientific article

MARK-AGE population: From the human model to new insights

scientific article

MARK-AGE standard operating procedures (SOPs): A successful effort

scientific article published on 26 March 2015

Medication Intake Is Associated with Lower Plasma Carotenoids and Higher Fat-Soluble Vitamins in the Cross-Sectional MARK-AGE Study in Older Individuals

scientific article published on 01 July 2020

Nutritional Factors Modulating Alu Methylation in an Italian Sample from The Mark-Age Study Including Offspring of Healthy Nonagenarians

scientific article published on 06 December 2019

Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35-74 Years) General Population: A Cross-Sectional Study in Six European Countries

scientific article

Pleiotropic Cellular Functions of PARP1 in Longevity and Aging: Genome Maintenance Meets Inflammation

scientific article published on September 19, 2012

Poly(ADP-RIBOSE) polymerase-1 (Parp-1) antagonizes topoisomerase I-dependent recombination stimulation by P53

scientific article

Prevalence and loads of torquetenovirus (TTV) in the European MARK-AGE Study population

scientific article published on 15 December 2019

Protection against Tetanus and Diphtheria in Europe: The impact of age, gender and country of origin based on data from the MARK-AGE Study

scientific article published on 7 October 2017

Quality control data of physiological and immunological biomarkers measured in serum and plasma

scientific article

Reconfiguration of DNA methylation in aging

scientific article

Stress Hormone-Mediated DNA Damage Response--Implications for Cellular Senescence and Tumour Progression

scientific article published on October 2015

Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors

scientific article

Synergistic Effects of Weightlessness, Isoproterenol, and Radiation on DNA Damage Response and Cytokine Production in Immune Cells

journal article from 'International Journal of Molecular Sciences' published in 2018

The MARK-AGE phenotypic database: Structure and strategy

scientific article published on 27 March 2015

The Radioprotective Effect of Procaine and Procaine-Derived Product Gerovital H3 in Lymphocytes from Young and Aged Individuals

scientific article published on 24 June 2020

The automated FADU-assay, a potential high-throughput in vitro method for early screening of DNA breakage.

scientific article published in January 2011

Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death

scientific article