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List of works by Vasilis Vasiliou

A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity.

scientific article

A new era in the discovery of de novo mutations underlying human genetic disease

scientific article published on 12 December 2012

A new home for Human Genomics ⬇️

scientific article published on July 5, 2012

AB049. Aldehyde dehydrogenases: from cancer stem cells to inborn errors of metabolism.

scientific article

ALDH16A1 is a novel non-catalytic enzyme that may be involved in the etiology of gout via protein–protein interactions with HPRT1 ⬇️

scientific article published on January 21, 2013

ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets.

scientific article

ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways

scientific article published on 7 May 2015

ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools

scientific article published on 6 November 2012

ALDH1B1 links alcohol consumption and diabetes

scientific article published on 15 June 2015

ALDH3A1 Plays a Functional Role in Maintenance of Corneal Epithelial Homeostasis

scientific article published on 11 January 2016

ALDH3A1: a corneal crystallin with diverse functions

scientific article

Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers

scientific article

Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.

scientific article published on 18 November 2005

Aldehyde Dehydrogenase 1B1 as a Modulator of Pancreatic Adenocarcinoma.

scientific article

Aldehyde dehydrogenase (ALDH) superfamily in plants: gene nomenclature and comparative genomics ⬇️

scientific article published on September 25, 2012

Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer.

scientific article published on 7 January 2011

Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer.

scientific article

Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice.

scientific article

Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity.

scientific article published on 4 December 2013

Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissues

scientific article

Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity

scientific article

Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress

scientific article

Aldehyde dehydrogenase gene superfamily: the 2000 update.

scientific article

Aldehyde dehydrogenase genes

scientific article published on 01 January 1997

Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application

scientific article

Aldehyde dehydrogenases are regulators of hematopoietic stem cell numbers and B-cell development.

scientific article published on 20 December 2011

Aldehyde dehydrogenases in acute myeloid leukemia.

scientific article published on March 2014

Aldehyde dehydrogenases in cellular responses to oxidative/electrophilic stress

scientific article

Aldh3a1 protects human corneal epithelial cells from ultraviolet- and 4-hydroxy-2-nonenal-induced oxidative damage.

scientific article published on May 2003

Analysis of the glutathione S-transferase (GST) gene family

scientific article

Antioxidant defenses in the ocular surface.

scientific article

Antioxidant function of corneal ALDH3A1 in cultured stromal fibroblasts.

scientific article

Arachidonic acid suppresses growth of human lung tumor A549 cells through down-regulation of ALDH3A1 expression.

scientific article published on 10 February 2006

Aromatase inhibitors induced autoimmune disorders in patients with breast cancer: A review

scientific article published on 23 April 2016

Assessment of cortisol and ACTH responses to the desmopressin test in patients with Cushing's syndrome and simple obesity

scientific article published on 01 October 1999

Auto-deconvolution and molecular networking of gas chromatography-mass spectrometry data

scientific article published on 09 November 2020

Beyond genomics: understanding exposotypes through metabolomics

scientific article

Catalase deletion promotes prediabetic phenotype in mice.

scientific article

Changes in Human Genomics.

scientific article published in January 2011

Changes in the inducibility of a hepatic aldehyde dehydrogenase by various effectors

scientific article published on 01 January 1989

Characterization of 4-hydroxy-2-nonenal metabolism in stellate cell lines derived from normal and cirrhotic rat liver

scientific journal article

Comparative genomics, molecular evolution and computational modeling of ALDH1B1 and ALDH2.

scientific article published on 13 December 2012

Corneal aldehyde dehydrogenases: multiple functions and novel nuclear localization

scientific article

Corneal haze phenotype in Aldh3a1-null mice: In vivo confocal microscopy and tissue imaging mass spectrometry.

scientific article

Dead enzymes in the aldehyde dehydrogenase gene family: role in drug metabolism and toxicology.

scientific article

Discovery of Orally Bioavailable, Quinoline-based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.

scientific article published on 16 May 2018

Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases

scientific article

Duane retraction syndrome, nystagmus, retinal pigment epitheliopathy and epiretinal membrane with micro- and pachygyria, developmental delay, hearing loss and craniopharyngioma.

scientific article published in March 2009

Editorial

Effect of various chemicals on the aldehyde dehydrogenase activity of the rat liver cytosol.

scientific article

Effects of cannabis and tobacco on the enzymes of alcohol metabolism in the rat

scientific article published on 01 January 1991

Engineered Animal Models Designed for Investigating Ethanol Metabolism, Toxicity and Cancer

scientific article published on 01 January 2018

Environmental influences in the etiology of colorectal cancer: the premise of metabolomics

scientific article

Enzymatic mechanisms of ethanol oxidation in the brain.

scientific article published in September 2006

Enzyme induction by L-buthionine (S,R)-sulfoximine in cultured mouse hepatoma cells.

scientific article published on April 1995

Ethanol induces skin hyperpigmentation in mice with aldehyde dehydrogenase 2 deficiency

scientific article published on 02 February 2019

Ethanol reduces lifespan, body weight, and serum alanine aminotransferase level of aldehyde dehydrogenase 2 knockout mouse.

scientific article published on 13 June 2014

Eukaryotic aldehyde dehydrogenase (ALDH) genes: human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping

scientific article (publication date: August 1999)

Evaluation of potential carcinogenicity of organic chemicals in synthetic turf crumb rubber

scientific article published on 24 October 2018

Evolutionary divergence and functions of the ADAM and ADAMTS gene families

scientific article

Evolutionary divergence and functions of the human acyl-CoA thioesterase gene ( ACOT ) family

scientific article

Evolutionary divergence and functions of the human interleukin (IL) gene family

scientific article

Expression and initial characterization of human ALDH3B1

scientific article

Extrahepatic expression of NAD(P)H:menadione oxidoreductase, UDP glucuronosyltransferase-1A6, microsomal aldehyde dehydrogenase, and hepatic nuclear factor-1 alpha mRNAs in ch/ch and 14CoS/14CoS mice

scientific article published on 01 April 1997

Focus on molecules: ALDH1A1: from lens and corneal crystallin to stem cell marker.

scientific article published on 23 April 2011

Four amino acid changes are associated with the Aldh3a1 locus polymorphism in mice which may be responsible for corneal sensitivity to ultraviolet light

scientific journal article

Gene array profiles of alcohol and aldehyde metabolizing enzymes in brains of C57BL/6 and DBA/2 mice

scientific article published in October 2006

Genetic differences in alcohol drinking preference between inbred strains of mice.

scientific article published in June 1997

Genetic tests obtainable through pharmacies: the good, the bad, and the ugly

scientific article published on 8 July 2013

Genome-wide identification and analysis of grape aldehyde dehydrogenase (ALDH) gene superfamily

scientific article

Glutathione Primes T Cell Metabolism for Inflammation

scientific article published on 01 June 2017

Glutathione and Transsulfuration in Alcohol-Associated Tissue Injury and Carcinogenesis

scientific article published on 01 January 2018

Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation

scientific article published on 10 September 2018

Glutathione defense mechanism in liver injury: Insights from animal models ⬇️

scientific article published on July 12, 2013

Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells

scientific article published on 04 April 2022

Heme oxygenase 1 protects ethanol-administered liver tissue in Aldh2 knockout mice.

scientific article published on 4 March 2016

Hepatic metabolic adaptation in a murine model of glutathione deficiency

scientific article published on 20 February 2019

Human ALDH1B1 polymorphisms may affect the metabolism of acetaldehyde and all-trans retinaldehyde--in vitro studies and computational modeling.

scientific article

Human ATP-binding cassette (ABC) transporter family

scientific article

Human aldehyde dehydrogenase 3A1 (ALDH3A1): biochemical characterization and immunohistochemical localization in the cornea

scientific article

Human aldehyde dehydrogenase genes: alternatively spliced transcriptional variants and their suggested nomenclature

scientific article

Human genomics begins ePub ahead of print and a discussion forum aiming to bridge academia with the pharmaceutical industry.

scientific article published on July 2011

Importance of inverse correlation between ALDH3A1 and PPARγ in tumor cells and tissue regeneration.

scientific article published on 18 January 2011

Improved drug therapy: triangulating phenomics with genomics and metabolomics.

scientific article

Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells

scientific article published on 06 March 2019

Involvement of p65 in the regulation of NF-kappaB in rat hepatic stellate cells during cirrhosis.

scientific article published on July 2000

Involvement of the electrophile responsive element and p53 in the activation of hepatic stellate cells as a response to electrophile menadione ⬇️

scientific article published on May 15, 2003

Lack of response of the rat liver "class 3" cytosolic aldehyde dehydrogenase to toxic chemicals, glutathione depletion, and other forms of stress

scientific article published on 01 August 1994

Letter to the editor for "Update of the human and mouse Fanconi anemia genes".

scientific article published on 4 July 2016

Ligands of four receptors in the nuclear steroid/thyroid hormone superfamily inhibit induction of rat cytosolic aldehyde dehydrogenase-3 (ALDH3c) by 3-methylcholanthrene

scientific article published on 01 December 1995

Mechanisms for PDGF, a Serum Cytokine, Stimulating Loss of Corneal Keratocyte Crystallins ⬇️

scientific article published on September 1, 2013

Mechanisms involved in the protection of UV-induced protein inactivation by the corneal crystallin ALDH3A1

scientific article published on 11 December 2006

Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart.

scientific article published on 8 October 2009

Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins

scientific journal article

Molecular characterization, expression analysis, and role of ALDH3B1 in the cellular protection against oxidative stress

scientific article

Molecular cloning and baculovirus expression of the rabbit corneal aldehyde dehydrogenase (ALDH1A1) cDNA.

scientific article

Molecular cloning and oxidative modification of human lens ALDH1A1: implication in impaired detoxification of lipid aldehydes.

scientific article

Molecular cloning, baculovirus expression, and tissue distribution of the zebrafish aldehyde dehydrogenase 2.

scientific article published on 9 February 2005

Molecular mechanisms of ALDH3A1-mediated cellular protection against 4-hydroxy-2-nonenal

scientific article

Mouse class 3 aldehyde dehydrogenases

scientific article published on 01 January 1995

Mouse dioxin-inducible NAD(P)H: menadione oxidoreductase: NMO1 cDNA sequence and genetic differences in mRNA levels.

scientific article published on December 1994

Mouse dioxin-inducible cytosolic aldehyde dehydrogenase-3: AHD4 cDNA sequence, genetic mapping, and differences in mRNA levels

scientific journal article

Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice

scientific article

Myofibroblast differentiation modulates keratocyte crystallin protein expression, concentration, and cellular light scattering.

scientific article published on 16 February 2012

Negative regulation of the murine cytosolic aldehyde dehydrogenase-3 (Aldh-3c) gene by functional CYP1A1 and CYP1A2 proteins

scientific article published on August 31, 1992

Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase.

scientific article published on 22 March 2007

Nitrogen mustard-induced corneal injury involves the sphingomyelin-ceramide pathway.

scientific article published on 9 November 2017

Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily

scientific article

Ocular aldehyde dehydrogenases: protection against ultraviolet damage and maintenance of transparency for vision.

scientific article published on 23 October 2012

Omics Screening for Pharmaceutical Efficacy and Safety in Clinical Practice ⬇️

scientific article published on March 16, 2012

Ontogenesis and expression of ALDH activity in the skin and the eye of the rat.

scientific article published in January 1997

Oral N-acetylcysteine rescues lethality of hepatocyte-specific Gclc-knockout mice, providing a model for hepatic cirrhosis.

scientific article

Overview of PAX gene family: analysis of human tissue-specific variant expression and involvement in human disease

scientific article published on 29 July 2020

Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education.

scientific article

Prepubertal regulation of the rat dioxin-inducible aldehyde dehydrogenase (ALDH3)

scientific article published on 01 January 1999

Prioritization of reproductive toxicants in unconventional oil and gas operations using a multi-country regulatory data-driven hazard assessment

scientific article published on 21 May 2018

Quantification of Neural Ethanol and Acetaldehyde Using Headspace GC-MS

scientific article published on 8 August 2016

Quiescent keratocytes fail to repair MMC induced DNA damage leading to the long-term inhibition of myofibroblast differentiation and wound healing ⬇️

scientific article published on July 4, 2012

Racemic Salsolinol and its Enantiomers Act as Agonists of the μ-Opioid Receptor by Activating the Gi Protein-Adenylate Cyclase Pathway

scientific article published on January 2016

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2.

scientific article published on 15 September 2016

Removal of acetaldehyde from the body.

scientific article published on January 2007

Response of [Ah] battery genes to compounds that protect against menadione toxicity

scientific article published on 01 November 1995

Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition

scientific article published on 7 December 2012

Reviewer acknowledgement 2014

Reviewer acknowledgement 2015

Reviewer acknowledgement 2015.

scientific article published on 27 March 2015

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family

scientific article

Role of Mitochondrial Aldehyde Dehydrogenase in Nitrate Tolerance ⬇️

scientific article published on November 1, 2003

Role of aldehyde dehydrogenases in endogenous and xenobiotic metabolism.

scientific article

Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism.

scientific article published in May 2004

Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction.

scientific article published on June 1993

Roles of defective ALDH2 polymorphism on liver protection and cancer development.

scientific article

Scallop lens Omega-crystallin (ALDH1A9): a novel tetrameric aldehyde dehydrogenase.

scientific article published on 8 August 2006

Structural and functional modifications of corneal crystallin ALDH3A1 by UVB light

scientific article

Studies on the induction of rat class 3 aldehyde dehydrogenase.

scientific article published on January 1995

Synergistic inhibition of hepatocellular carcinoma growth by cotargeting chromatin modifying enzymes and poly (ADP-ribose) polymerases.

scientific article

Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1.

scientific article published on 9 March 2017

The accuracy of self-reported drug ingestion histories in emergency department patients

scientific article

The desmopressin and combined CRH-desmopressin tests in the differential diagnosis of ACTH-dependent Cushing's syndrome: constraints imposed by the expression of V2 vasopressin receptors in tumors with ectopic ACTH secretion.

scientific article

The effects of alcohol and aldehyde dehydrogenases on disorders of hematopoiesis.

scientific article

The exact mechanism of ethanol-associated carcinogenesis still remains unknown, a number of factors may contribute to the development of alcohol-associated cancer, including ethanol metabolising enzymes. Editorial.

scientific article published on January 2009

The genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy due to mutations in ALDH7A1

scientific article

The lack of AHD4 induction by TCDD in corneal cells may involve tissue-specific regulatory proteins

scientific article published on 01 January 1999

The mechanism of alcohol intolerance produced by various therapeutic agents.

scientific article published in May 1986

The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system.

scientific article

The role of hyperosmotic stress in inflammation and disease

scientific article

Transcriptomic analysis and plasma metabolomics in Aldh16a1-null mice reveals a potential role of ALDH16A1 in renal function

scientific article published on 27 February 2017

Transgenic mouse models for alcohol metabolism, toxicity, and cancer

scientific article

Ultraviolet radiation decreases expression and induces aggregation of corneal ALDH3A1

scientific article published on 01 February 2003

Ultraviolet radiation: cellular antioxidant response and the role of ocular aldehyde dehydrogenase enzymes.

scientific article

Update of the NAD(P)H:quinone oxidoreductase (NQO) gene family

scientific article (publication date: March 2006)

Update of the human and mouse Fanconi anemia genes

scientific article

Update of the human and mouse SERPIN gene superfamily

scientific article

Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily.

scientific article published on October 2011

Update on the aldehyde dehydrogenase gene (ALDH) superfamily ⬇️

scientific article (publication date: May 2011)

Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom"

article

Varying levels of aldehyde dehydrogenase activity in adult murine marrow hematopoietic stem cells are associated with engraftment and cell cycle status.

scientific article published on 6 June 2012

Welcome back to Human Genomics. ⬇️

scientific article published on September 2008

Welcome to Volume 4, Issue 1 of Human Genomics.

scientific article published on October 2009

Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level.

scientific article published on 27 February 2018

Yale school of public health symposium on lifetime exposures and human health: the exposome; summary and future reflections.

scientific article published on 8 December 2017

Zoxazolamine-induced paralysis in two rat substrains: differences in hepatic drug metabolism

scientific journal article

aldh7a1 regulates eye and limb development in zebrafish.

scientific article

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