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List of works by Graham Simmons

A 3.4-Å cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles

scientific article published on 11 August 2020

A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus.

scientific article published on September 1997

A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease

scientific article

A novel rhabdovirus associated with acute hemorrhagic fever in central Africa

scientific article published in September 2012

A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms

scientific article

A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry.

scientific article

Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States

scientific article

Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity

scientific article published on April 1998

An attenuated replication-competent chikungunya virus with a fluorescently tagged envelope

scientific article published on 31 July 2018

Analysis of SARS-CoV-2 Antibodies in COVID-19 Convalescent Plasma using a Coronavirus Antigen Microarray

scientific article published on 17 April 2020

Analysis of SARS-CoV-2 antibodies in COVID-19 convalescent blood using a coronavirus antigen microarray

scientific article

Arbovirus Diagnostics: From Bad to Worse due to Expanding Dengue Virus Vaccination and Zika Virus Epidemics

scientific article published on 30 December 2017

Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enh

scientific article published on July 2004

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress

scientific article

CD4-independent infection by HIV-2 (ROD/B): use of the 7-transmembrane receptors CXCR-4, CCR-3, and V28 for entry

scientific article published on April 1997

Cell-to-cell fusion, but not virus entry in macrophages by T-cell line tropic HIV-1 strains: a V3 loop-determined restriction

scientific article published on June 1995

Characterization of Chikungunya pseudotyped viruses: Identification of refractory cell lines and demonstration of cellular tropism differences mediated by mutations in E1 glycoprotein

scientific article published on 18 August 2009

Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

scholarly article

Characterization of the Bas-Congo virus glycoprotein and its function in pseudotyped viruses

scientific article published on 19 June 2013

Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease

scientific article published on 12 October 2011

Coreceptor ligand inhibition of fetal brain cell infection by HIV type 1.

scientific article published in July 1999

DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells.

scientific article published on January 2003

DC-SIGN and DC-SIGNR interact with the glycoprotein of Marburg virus and the S protein of severe acute respiratory syndrome coronavirus

scientific article published on November 2004

Detection of host immune responses in acute phase sera of spontaneous resolution versus persistent hepatitis C virus infection

scientific article published on 25 April 2012

Development and application of a high-throughput microneutralization assay: lack of xenotropic murine leukemia virus-related virus and/or murine leukemia virus detection in blood donors

scientific article published in February 2012

Development of novel entry inhibitors targeting emerging viruses

scientific article published on October 2012

Development of sensitive single-round pol or env RT-PCR assays to screen for XMRV in multiple sample types

scientific article published on 25 October 2011

Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion

scientific article published on 23 March 2011

Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR

scientific article

Differential activation of CC chemokine receptors by AOP-RANTES

scientific article

Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63.

scientific article

Duration of Dengue Viremia in Blood Donors and Relationships Between Donor Viremia, Infection Incidence and Clinical Case Reports During a Large Epidemic

scientific article published on April 2016

Ebola Virus Neutralizing Antibodies Detectable in Survivors of theYambuku, Zaire Outbreak 40 Years after Infection

scientific article published on 14 December 2017

Ebola virus glycoproteins induce global surface protein down-modulation and loss of cell adherence

scientific article

Emerging infectious agents and the nation's blood supply: responding to potential threats in the 21st century ⬇️

scientific article published on June 13, 2012

Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry

scientific article published on June 2006

Evidence for a post-entry barrier to R5 HIV-1 infection of CD4 memory T cells

scientific article

Expanded tropism and altered activation of a retroviral glycoprotein resistant to an entry inhibitor peptide

scientific article published on January 2006

Exposure of epitope residues on the outer face of the chikungunya virus envelope trimer determines antibody neutralizing efficacy

scientific article

Failure to confirm XMRV/MLVs in the blood of patients with chronic fatigue syndrome: a multi-laboratory study

scientific article

Filovirus entry

scientific article published on January 2013

Filoviruses utilize glycosaminoglycans for their attachment to target cells

scientific article published on 9 January 2013

First cases of Zika virus-infected US blood donors outside states with areas of active transmission

scientific article (publication date: February 2017)

Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection

scientific article published on December 2003

HIV-1 tropism and co-receptor use

scientific article published in Nature

High Incidence of Chikungunya Virus and Frequency of Viremic Blood Donations during Epidemic, Puerto Rico, USA, 2014

scientific article (publication date: July 2016)

Higher Serum Alanine Transaminase Levels in Male Urokinase-Type Plasminogen Activator-Transgenic Mice Are Associated With Improved Engraftment of Hepatocytes but not Liver Sinusoidal Endothelial Cells

scientific article

Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors

scientific article published on September 2006

Host genetic basis for hepatitis C virus clearance: a role for blood collection centers

scientific article

Human keratinocytes restrict chikungunya virus replication at a post-fusion step

scientific article published on 8 December 2014

Identification of murine T-cell epitopes in Ebola virus nucleoprotein

scientific article published on January 2004

In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer

scientific article

Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2.

scientific article

Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin

scientific article

Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay

scientific article

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

scientific article

Inhibitory antibodies targeting emerging viruses: advancements and mechanisms

scientific article

Interferon-Induced Transmembrane Protein-Mediated Inhibition of Host Cell Entry of Ebolaviruses

scientific article

Is CD4 sufficient for HIV entry? Cell surface molecules involved in HIV infection

scientific article published on October 1993

Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis

scientific article

No evidence for XMRV nucleic acids, infectious virus or anti-XMRV antibodies in Canadian patients with chronic fatigue syndrome

scientific article

No evidence of murine leukemia virus-related viruses in live attenuated human vaccines

scientific article

No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected

scientific article

Phylogenetic analysis of multiple heterosexual transmission events involving subtype b of HIV type 1.

scientific article

Plasma transfusion–transmission of Zika virus in mice and macaques

scientific article published in 2023

Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist.

scientific article published on April 1997

Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity

scientific article

Pseudotyping Viral Vectors With Emerging Virus Envelope Proteins

scientific article

SARS-CoV-2 infection induces germinal center responses with robust stimulation of CD4 T follicular helper cells in rhesus macaques

scientific article published on 08 July 2020

SARS-CoV-2 infection induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques

scientific article published on 14 August 2020

The Blood Xenotropic Murine Leukemia Virus–Related Virus Scientific Research Working Group: mission, progress, and plans ⬇️

scientific article published on March 1, 2011

The signal peptide of the ebolavirus glycoprotein influences interaction with the cellular lectins DC-SIGN and DC-SIGNR.

scientific article published on July 2006

The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies

scientific article published on 6 March 2013

Zika Virus Tissue and Blood Compartmentalization in Acute Infection of Rhesus Macaques

scientific article

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