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List of works by Vera Gorbunova

A conserved NAD+ binding pocket that regulates protein-protein interactions during aging

scientific article

A hairy tale: SIRT7 safeguards skin stem cells during aging

scientific article published on 16 August 2020

A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors.

scientific article

A new hyperrecombinogenic mutant of Nicotiana tabacum.

scientific article

A nuclear protein that binds specifically to several maize transposons is not essential for Ds1 excision.

scientific article published in April 2000

A review of the biomedical innovations for healthy longevity

scientific article

AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11.

scientific article published on 2 October 2017

ARDD 2020: from aging mechanisms to interventions

scientific article published on 30 December 2020

ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma

scientific article published on March 2016

Accurate translation is important for longevity

scientific article published on 12 March 2018

Adenoviral vector driven by a minimal Rad51 promoter is selective for p53-deficient tumor cells

scientific article

Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials

scientific article

Analysis of DNA double-strand break (DSB) repair in mammalian cells.

scientific article published on 8 September 2010

Analysis of extrachromosomal Ac/Ds transposable elements.

scientific article published on May 2000

Beyond Making Ends Meet: DNA-PK, Metabolism, and Aging.

scientific article published in May 2017

Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism

scientific article

Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity

scientific article

Cell divisions are required for L1 retrotransposition

scientific article published on 4 December 2006

Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53.

scientific article published on March 2001

Changes in DNA repair during aging.

scientific article

Changes in the level and distribution of Ku proteins during cellular senescence.

scientific article published on 07 August 2007

Characterization of naked mole‐rat hematopoiesis reveals unique stem and progenitor cell patterns and neotenic traits

scientific article published in 2022

Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human

scientific article published on 28 January 2015

Comparative genetics of longevity and cancer: insights from long-lived rodents

scientific article

Comparison of nonhomologous end joining and homologous recombination in human cells.

scientific article published on 20 August 2008

Cross-species comparison of proteome turnover kinetics

scientific article published on 10 January 2018

DNA double strand break repair, aging and the chromatin connection.

scientific article published on 15 February 2016

DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells.

scientific article published on July 2009

DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells

scientific article

DNA repair in species with extreme lifespan differences

scientific article

Dangerous Entrapment for NRF2.

scientific article published in June 2016

Enhanced cellular radiosensitivity induced by cofilin-1 over-expression is associated with reduced DNA repair capacity.

scientific article published on 19 March 2013

Establishing Primary Adult Fibroblast Cultures From Rodents

scientific article published on October 5, 2010

Evolution of mammalian longevity: age-related increase in autophagy in bats compared to other mammals

scientific article published on 21 March 2021

Evolution of telomere maintenance and tumour suppressor mechanisms across mammals

scientific article published in March 2018

Forever young?  Exploring the link between rapamycin, longevity and cancer

Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells

scientific article published on 8 May 2017

Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax.

scientific article published on 3 June 2014

HG-02ATRX LOSS PROMOTES TUMOR GROWTH AND IMPAIRS GENETIC STABILITY IN GLIOBLASTOMA.

scientific article published on 21 April 2015

Haploinsufficiency of Trp53 dramatically extends the lifespan of Sirt6-deficient mice

scientific article published on 23 February 2018

How plants make ends meet: DNA double-strand break repair

scientific article published on 01 July 1999

Human Genomics. Sleeping dogs of the genome

scientific article

Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat

scientific article

IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response

scientific article published on 01 February 2019

IGF1R levels in the brain negatively correlate with longevity in 16 rodent species.

scientific article published on April 2013

INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform

scientific article

JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks.

scientific article

Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age

scientific article

Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

scientific article published on 18 July 2020

Lipidome determinants of maximal lifespan in mammals

scientific article

Mechanisms of cancer resistance in long-lived mammals

scientific article published on 5 April 2018

Mitochondrial inverted repeats strongly correlate with lifespan: mtDNA inversions and aging

scientific article

Molecular Mechanisms Determining Lifespan in Short- and Long-Lived Species

scientific article

Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming.

scientific article

Naked mole rat TRF1 safeguards glycolytic capacity and telomere replication under low oxygen

scientific article published in 2021

Naked mole rat cells display more efficient excision repair than mouse cells

scientific article published on 01 June 2018

Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence.

scientific article published on 5 February 2018

Naked mole-rat has increased translational fidelity compared with the mouse, as well as a unique 28S ribosomal RNA cleavage

scientific article

Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties

scientific article published on 12 May 2020

Naked mole-rats are extremely resistant to post-traumatic osteoarthritis

scientific article published on 28 October 2020

Non-canonical aging model systems and why we need them.

scientific article published on 20 March 2017

Non-homologous DNA end joining in plant cells is associated with deletions and filler DNA insertions

scientific article published on November 15, 1997

Novel husbandry techniques support survival of naked mole rat (Heterocephalus glaber) pups

scientific article

Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity

scientific article published on 4 November 2015

P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescence

scientific article

PTPS-15ATRX LOSS PROMOTES TUMOR GROWTH AND IMPAIRS NON-HOMOLOGOUS END JOINING DNA REPAIR IN GLIOMA.

scientific article

Pericellular Brush and Mechanics of Guinea Pig Fibroblast Cells Studied with AFM.

scientific article published on July 2016

Proteomics of Long-Lived Mammals

scientific article published on 09 January 2020

Rad51 Promoter-Targeted Gene Therapy Is Effective for In Vivo Visualization and Treatment of Cancer

scientific article published on October 18, 2011

Regulation of Rad51 promoter

scientific article

Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair.

scientific article published on September 2011

Replicatively senescent cells are arrested in G1 and G2 phases

scientific article published on June 1, 2012

Reply to: Transformation of naked mole-rat cells

scientific article published on 01 July 2020

Rodents for comparative aging studies: from mice to beavers

scientific article (publication date: September 2008)

SIRT1 as a therapeutic target in inflammaging of the pulmonary disease

scientific article

SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells

scientific article

SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age.

scientific article

SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner

scientific article

SIRT6: a promising target for cancer prevention and therapy.

scientific article published on January 2014

SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair

scientific article

Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan.

scientific article published on 07 May 2016

Short-term calorie restriction enhances DNA repair by non-homologous end joining in mice

scientific article published on 14 August 2020

TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination.

scholarly article

Telomerase activity coevolves with body mass not lifespan

scientific article published on 14 December 2006

Telomerase as a Growth-Promoting Factor

scientific article published on November 1, 2003

Ten things you should know about transposable elements

scientific article published on 19 November 2018

The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat

scientific article published on 22 December 2015

The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations

scientific article

The conundrum of human immune system "senescence"

scientific article published on 16 September 2020

Translation fidelity coevolves with longevity

scientific article published on 13 July 2017

Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.

scientific article published on May 2017

Use of the Rad51 promoter for targeted anti-cancer therapy

scholarly article

Utilization of Rad51C promoter for transcriptional targeting of cancer cells.

scientific article