List of works by Kuo-Chen Chou

2L-PCA: a two-level principal component analyzer for quantitative drug design and its applications

scientific article published on August 2017

2L-piRNA: A Two-Layer Ensemble Classifier for Identifying Piwi-Interacting RNAs and Their Function

scientific article

3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design

scientific article published on 08 February 2007

A Novel Modeling in Mathematical Biology for Classification of Signal Peptides

scientific article published on 18 January 2018

A comparison of computational methods for identifying virulence factors

scientific article

A fast and accurate method for predicting pKa of residues in proteins.

scientific article published in January 2010

A multi-label classifier for predicting the subcellular localization of gram-negative bacterial proteins with both single and multiple sites

scientific article

A new hybrid approach to predict subcellular localization of proteins by incorporating gene ontology ⬇️

scientific article published on November 21, 2003

A new method for predicting the subcellular localization of eukaryotic proteins with both single and multiple sites: Euk-mPLoc 2.0

scientific article

A new nucleotide-composition based fingerprint of SARS-CoV with visualization analysis

scientific article

A novel approach to predict active sites of enzyme molecules

scientific article published in April 2004

A novel fingerprint map for detecting SARS-CoV.

scientific article

A novel sequence-based method for phosphorylation site prediction with feature selection and analysis

scientific article

A pharmacophore model specific to active site of CYP1A2 with a novel molecular modeling explorer and CoMFA.

scientific article

A probability cellular automaton model for hepatitis B viral infections

scientific article published on 08 February 2006

A sequence-based approach for predicting protein disordered regions

scientific article

A study on the correlation of G-protein-coupled receptor types with amino acid composition.

scientific article published in September 2002

A top-down approach to enhance the power of predicting human protein subcellular localization: Hum-mPLoc 2.0

scientific article

A tribute to a living legend

scientific article published in September 2012

AFP-Pred: A random forest approach for predicting antifreeze proteins from sequence-derived properties.

scientific article published on 4 November 2010

Advances in visual representation of molecular potentials

scientific article published on 30 April 2010

Agaritine and its derivatives are potential inhibitors against HIV proteases

scientific article

An Insightful 10-year Recollection Since the Emergence of the 5-steps Rule

scientific article published on 01 January 2019

An Unprecedented Revolution in Medicinal Chemistry Driven by the Progress of Biological Science

scientific article

An allosteric mechanism inferred from molecular dynamics simulations on phospholamban pentamer in lipid membranes

scientific article

An application of gene comparative image for predicting the effect on replication ratio by HBV virus gene missense mutation

scientific article published on 24 March 2005

An in-depth analysis of the biological functional studies based on the NMR M2 channel structure of influenza A virus

scientific article published on 6 November 2008

An insightful 20-year recollection since the birth of pseudo amino acid components

scientific article published on 18 February 2020

Analogue inhibitors by modifying oseltamivir based on the crystal neuraminidase structure for treating drug-resistant H5N1 virus

scientific article

Analysis and prediction of the metabolic stability of proteins based on their sequential features, subcellular locations and interaction networks

scientific article

Analysis of protein pathway networks using hybrid properties.

article

Antithrombin, an Important Inhibitor in Blood Clots

scientific article published on 23 September 2015

Apolipoprotein E gene variants of Alzheimer's disease and vascular dementia patients in a community population of Nanking.

scientific article

Application of SVM to predict membrane protein types

scientific article published in February 2004

Application of bioinformatics in search for cleavable peptides of SARS-CoV M(pro) and chemical modification of octapeptides

scientific article published on May 2005

Artificial neural network method for predicting protein secondary structure content.

scientific article published in June 2002

Artificial neural network model for predicting protein subcellular location.

scientific article published in January 2002

Assessment of chemical libraries for their druggability

scientific article

Association of EGF rs4444903 and XPD rs13181 polymorphisms with cutaneous melanoma in Caucasians

scientific article published on January 2015

Benchmark data for identifying DNA methylation sites via pseudo trinucleotide composition

scientific article

Benchmark data for identifying N(6)-methyladenosine sites in the Saccharomyces cerevisiae genome

scientific article

Binding mechanism of H5N1 influenza virus neuraminidase with ligands and its implication for drug design

scientific article published in May 2009

Binding mechanism of coronavirus main proteinase with ligands and its implication to drug design against SARS.

scientific article published in August 2003

Binding of CYP2C9 with diverse drugs and its implications for metabolic mechanism.

scientific article published in May 2009

Bio-support vector machines for computational proteomics

scientific article published on 29 January 2004

Bioinformatical analysis of G-protein-coupled receptors

scientific article published in September 2002

Boosting classifier for predicting protein domain structural class

scientific article published in August 2005

Cell-PLoc: a package of Web servers for predicting subcellular localization of proteins in various organisms

scientific article

Cellular automata and its applications in protein bioinformatics

scientific article published on September 2011

ChemInform Abstract: Comparative Study of Topological Indices of Macro/Supramolecular RNA Complex Networks

Chlorella vulgaris Induces Apoptosis of Human Non-Small Cell Lung Carcinoma (NSCLC) Cells

scientific article published on 9 May 2017

Classification and analysis of regulatory pathways using graph property, biochemical and physicochemical property, and functional property

scientific article

Classification and prediction of β–turn types by neural network

Combining evolutionary information extracted from frequency profiles with sequence-based kernels for protein remote homology detection

scientific article published on 5 December 2013

Comparative study of topological indices of macro/supramolecular RNA complex networks.

scientific article

Computational approach to drug design for oxazolidinones as antibacterial agents

scientific article published on 01 November 2007

Computational methods for protein-protein interaction and their application

scientific article

Computational studies of the binding mechanism of calmodulin with chrysin

scientific article published on 22 May 2007

Correlations of amino acids in proteins

scientific article published in December 2003

Corrigendum to “Predicting protein structural class by functional domain composition” [Biochem. Biophys. Res. Commun. 321 (2004) 1007–1009]

article

Coupling interaction between thromboxane A2 receptor and alpha-13 subunit of guanine nucleotide-binding protein

scientific article

Deciphering the effects of gene deletion on yeast longevity using network and machine learning approaches.

scientific article published on 8 January 2012

Design novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approach

scientific article

Designing inhibitors of M2 proton channel against H1N1 swine influenza virus

scientific article

Digital coding of amino acids based on hydrophobic index

scientific article

Docking and molecular dynamics simulations of peroxisome proliferator activated receptors interacting with pan agonist sodelglitazar

scientific article

Docking and molecular dynamics study on the inhibitory activity of novel inhibitors on epidermal growth factor receptor (EGFR).

scientific article

Drug candidates from traditional chinese medicines

scientific article

Energetic analysis of the two controversial drug binding sites of the M2 proton channel in influenza A virus

scientific article published on 12 March 2009

Ensemble classifier for protein fold pattern recognition

scientific article published on 3 May 2006

Erratum to "pLoc-mVirus: Predict subcellular localization of multi-location virus proteins via incorporating the optimal GO information into general PseAAC" [Gene 628 (2017) 315-321].

scientific article published on 27 November 2017

Erratum to "pLoc-mVirus: Predict subcellular localization of multi-location virus proteins via incorporating the optimal GO information into general PseAAC" [Gene 628 (2017) 315-321].

scientific article

Euk-mPLoc: a fusion classifier for large-scale eukaryotic protein subcellular location prediction by incorporating multiple sites

scientific article published on 31 March 2007

EzyPred: a top-down approach for predicting enzyme functional classes and subclasses

scientific article

Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics

scientific article

Fragment-based quantitative structure-activity relationship (FB-QSAR) for fragment-based drug design

scientific article

Fuzzy KNN for predicting membrane protein types from pseudo-amino acid composition.

scientific article published on 28 September 2005

GPCR-2L: predicting G protein-coupled receptors and their types by hybridizing two different modes of pseudo amino acid compositions.

scientific article published on 23 December 2010

GPCR-CA: A cellular automaton image approach for predicting G-protein-coupled receptor functional classes

scientific article

GPCR-GIA: a web-server for identifying G-protein coupled receptors and their families with grey incidence analysis.

scientific article published on 22 September 2009

Gestational Influenza Increases the Risk of Psychosis in Adults

scientific article published on 29 April 2015

Glycosylation of HIV-1 gp120 V3 loop: towards the rational design of a synthetic carbohydrate vaccine

scientific article published on January 2007

Gneg-mPLoc: a top-down strategy to enhance the quality of predicting subcellular localization of Gram-negative bacterial proteins

scientific article published on 20 January 2010

Gpos-PLoc: an ensemble classifier for predicting subcellular localization of Gram-positive bacterial proteins

scientific article published on 23 January 2007

Gpos-mPLoc: a top-down approach to improve the quality of predicting subcellular localization of Gram-positive bacterial proteins

scientific article published on January 2009

Graphic rule for drug metabolism systems

scientific article

HIV-1 gp120 V3 loop for structure-based drug design

scientific article

HIVcleave: a web-server for predicting human immunodeficiency virus protease cleavage sites in proteins

scientific article

HP-Lattice QSAR for dynein proteins: experimental proteomics (2D-electrophoresis, mass spectrometry) and theoretic study of a Leishmania infantum sequence.

scientific article

Hepatitis C virus network based classification of hepatocellular cirrhosis and carcinoma

scientific article

Heuristic molecular lipophilicity potential (HMLP): a 2D-QSAR study to LADH of molecular family pyrazole and derivatives

scientific article published in April 2005

Heuristic molecular lipophilicity potential (HMLP): lipophilicity and hydrophilicity of amino acid side chains.

scientific article published in April 2006

Hum-PLoc: a novel ensemble classifier for predicting human protein subcellular localization

scientific article published on 21 June 2006

Hum-mPLoc: an ensemble classifier for large-scale human protein subcellular location prediction by incorporating samples with multiple sites

scientific article published on 23 February 2007

Identification of DNA-binding proteins by incorporating evolutionary information into pseudo amino acid composition via the top-n-gram approach

scientific article published on 28 October 2014

Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network

scientific article

Identification of microRNA precursor with the degenerate K-tuple or Kmer strategy

scientific article published on 8 September 2015

Identification of proteases and their types

scientific article

Identification of protein-protein binding sites by incorporating the physicochemical properties and stationary wavelet transforms into pseudo amino acid composition

scientific article published on 16 September 2015

Identification of proteins interacting with human SP110 during the process of viral infections

scientific article published on 01 March 2011

Identification of real microRNA precursors with a pseudo structure status composition approach

scientific article

Identification of the N-terminal functional domains of Cdk5 by molecular truncation and computer modeling

scientific article

Identify catalytic triads of serine hydrolases by support vector machines

scientific article

Identifying the hub proteins from complicated membrane protein network systems.

scientific article published in May 2010

Impacts of Pseudo Amino Acid Components and 5-steps Rule to Proteomics and Proteome Analysis

scientific article published on 01 January 2019

Impacts of bioinformatics to medicinal chemistry

scientific article published on January 2015

Implications of Newly Identified Brain eQTL Genes and Their Interactors in Schizophrenia.

scientific article published on 11 July 2018

Improving the accuracy of predicting disulfide connectivity by feature selection

scientific article published on May 2010

In-depth comparison of somatic point mutation callers based on different tumor next-generation sequencing depth data

scientific article

Inhibitor design for SARS coronavirus main protease based on "distorted key theory".

scientific article

Insight into a molecular interaction force supporting peptide backbones and its implication to protein loops and folding

scientific article

Insight into the molecular switch mechanism of human Rab5a from molecular dynamics simulations

scientific article published on 9 October 2009

Insights from investigating the interaction of oseltamivir (Tamiflu) with neuraminidase of the 2009 H1N1 swine flu virus

scientific article published on 10 June 2009

Insights from investigating the interactions of adamantane-based drugs with the M2 proton channel from the H1N1 swine virus

scientific article published on 8 August 2009

Insights from modeling the 3D structure of DNA-CBF3b complex

scientific article published on September 2005

Insights from modeling the 3D structure of H5N1 influenza virus neuraminidase and its binding interactions with ligands

scientific article published on 19 April 2006

Insights from modeling the 3D structure of NAD(P)H-dependent D-xylose reductase of Pichia stipitis and its binding interactions with NAD and NADP.

scientific article published on 24 May 2007

Insights from modeling the 3D structure of New Delhi metallo-β-lactamse and its binding interactions with antibiotic drugs

scientific article

Insights from modeling the tertiary structure of human BACE2.

scientific article published in September 2004

Insights from modeling three-dimensional structures of the human potassium and sodium channels

scientific article

Insights from modelling the 3D structure of the extracellular domain of alpha7 nicotinic acetylcholine receptor

scientific article

Insights from studying the mutation-induced allostery in the M2 proton channel by molecular dynamics

scientific article published on 22 June 2010

Insights into the mutation-induced HHH syndrome from modeling human mitochondrial ornithine transporter-1.

scientific article

Investigation into adamantane-based M2 inhibitors with FB-QSAR.

scientific article published in July 2009

Knowledge-based computational intelligence development for predicting protein secondary structures from sequences

scientific article published on October 2008

Large-scale comparative assessment of computational predictors for lysine post-translational modification sites

Large-scale plant protein subcellular location prediction

scientific article published in February 2007

Large-scale predictions of gram-negative bacterial protein subcellular locations

scientific article published in December 2006

Low-frequency Fourier spectrum for predicting membrane protein types

scientific article published on October 2005

MULTiPly: a novel multi-layer predictor for discovering general and specific types of promoters

MULTiPly: a novel multi-layer predictor for discovering general and specific types of promoters

scientific article published in 2019

MemType-2L: a web server for predicting membrane proteins and their types by incorporating evolution information through Pse-PSSM.

scientific article

Metagenome Assembly Validation: Which Metagenome Contigs are Bona Fide?

Metallo-β-lactamases: structural features, antibiotic recognition, inhibition, and inhibitor design

scientific article published on January 2013

Methodology development for predicting subcellular localization and other attributes of proteins

scientific article published on August 2007

Mining biological data using self-organizing map.

scientific article

Modeling the tertiary structure of human cathepsin-E

scientific article (publication date: 27 May 2005)

Modelling extracellular domains of GABA-A receptors: subtypes 1, 2, 3, and 5.

scientific article

Modulation of Cytokine Network in the Comorbidity of Schizophrenia and Tuberculosis

scientific article published on 18 August 2015

Molecular dynamics simulations of CYP2E1

scientific article published on 01 March 2012

Molecular dynamics studies on the interactions of PTP1B with inhibitors: from the first phosphate-binding site to the second one.

scientific article published on 19 April 2009

Molecular insights of SAH enzyme catalysis and implication for inhibitor design

scientific article published on 16 September 2006

Molecular modeling and chemical modification for finding peptide inhibitor against severe acute respiratory syndrome coronavirus main proteinase

scientific article

Molecular modeling of cytochrome P450 and drug metabolism

scientific article published on May 2010

Molecular modeling of two CYP2C19 SNPs and its implications for personalized drug design

scientific article published in January 2008

Molecular modeling studies of peptide drug candidates against SARS

scientific article published on 01 May 2006

Molecular simulation to investigate the cofactor specificity for pichia stipitis Xylose reductase

scientific article

Molecular therapeutic target for type-2 diabetes

scientific article

Multiple field three dimensional quantitative structure-activity relationship (MF-3D-QSAR).

scientific article published in January 2008

NR-2L: a two-level predictor for identifying nuclear receptor subfamilies based on sequence-derived features

scientific article

Nearest neighbour algorithm for predicting protein subcellular location by combining functional domain composition and pseudo-amino acid composition.

scientific article

Novel inhibitor design for hemagglutinin against H1N1 influenza virus by core hopping method

scientific article

Nuc-PLoc: a new web-server for predicting protein subnuclear localization by fusing PseAA composition and PsePSSM.

scientific article published on 10 November 2007

Nucleosome positioning based on the sequence word composition.

scientific article

P-selectin cell adhesion molecule in inflammation, thrombosis, cancer growth and metastasis

scientific article published in August 2004

PREvaIL, an integrative approach for inferring catalytic residues using sequence, structural, and network features in a machine-learning framework

scientific article published on 30 January 2018

Pattern recognition methods for protein functional site prediction

scientific article

Peptide reagent design based on physical and chemical properties of amino acid residues

scientific article published in September 2007

Pharmacogenomics and personalized use of drugs

scientific article published on 01 January 2008

PhoglyStruct: Prediction of phosphoglycerylated lysine residues using structural properties of amino acids

scientific article published in Scientific Reports

Physics and chemistry-driven artificial neural network for predicting bioactivity of peptides and proteins and their design.

scientific article

Plant-mPLoc: a top-down strategy to augment the power for predicting plant protein subcellular localization

scientific article published in 2010

Polyprotein cleavage mechanism of SARS CoV Mpro and chemical modification of the octapeptide

scientific article published in November 2004

Positive-unlabelled learning of glycosylation sites in the human proteome

Possible drug candidates for Alzheimer's disease deduced from studying their binding interactions with alpha7 nicotinic acetylcholine receptor.

scientific article published in May 2009

Predict and analyze S-nitrosylation modification sites with the mRMR and IFS approaches

scientific article published on 11 December 2011

Predict drug-protein interaction in cellular networking

scientific article published on January 2013

Predicting 22 protein localizations in budding yeast.

scientific article published in October 2004

Predicting Anatomical Therapeutic Chemical (ATC) classification of drugs by integrating chemical-chemical interactions and similarities

scientific article

Predicting biological functions of compounds based on chemical-chemical interactions

scientific article

Predicting drug-target interaction networks based on functional groups and biological features

scientific article

Predicting drugs side effects based on chemical-chemical interactions and protein-chemical interactions

scientific article published on 04 September 2013

Predicting enzyme family class in a hybridization space.

scientific article

Predicting enzyme family classes by hybridizing gene product composition and pseudo-amino acid composition

article

Predicting enzyme subclass by functional domain composition and pseudo amino acid composition.

scientific article published in May 2005

Predicting eukaryotic protein subcellular location by fusing optimized evidence-theoretic K-Nearest Neighbor classifiers

scientific article published in August 2006

Predicting functions of proteins in mouse based on weighted protein-protein interaction network and protein hybrid properties

scientific article

Predicting membrane protein type by functional domain composition and pseudo-amino acid composition

article

Predicting membrane protein types by the LLDA algorithm

scientific article published on January 2008

Predicting protein fold pattern with functional domain and sequential evolution information

scientific article published on 19 October 2008

Predicting protein localization in budding yeast

scientific article published on 28 October 2004

Predicting protein oxidation sites with feature selection and analysis approach

scientific article published in January 2012

Predicting protein quaternary structure by pseudo amino acid composition

scientific article

Predicting protein quaternary structure by pseudo amino acid composition

article

Predicting protein structural class by functional domain composition

scientific article

Predicting protein structural class with AdaBoost Learner.

scientific article published in January 2006

Predicting protein structural classes with pseudo amino acid composition: an approach using geometric moments of cellular automaton image

scientific article

Predicting protein subcellular location by fusing multiple classifiers

scientific article published in October 2006

Predicting protein subnuclear location with optimized evidence-theoretic K-nearest classifier and pseudo amino acid composition

scientific article

Predicting protein-ligand binding sites based on an improved geometric algorithm.

scientific article published in October 2011

Predicting protein-protein interactions from sequences in a hybridization space

scientific article published on February 2006

Predicting secretory proteins of malaria parasite by incorporating sequence evolution information into pseudo amino acid composition via grey system model

scientific article

Predicting subcellular localization of proteins by hybridizing functional domain composition and pseudo-amino acid composition.

scientific article

Predicting subcellular localization of proteins in a hybridization space

scientific article published on 05 February 2004

Predicting the affinity of epitope-peptides with class I MHC molecule HLA-A*0201: an application of amino acid-based peptide prediction

scientific article published on 5 August 2007

Predicting the linkage sites in glycoproteins using bio-basis function neural network

scientific article published on 29 January 2004

Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition ⬇️

scientific article

Predicting transcriptional activity of multiple site p53 mutants based on hybrid properties

scientific article

Prediction and analysis of protein palmitoylation sites.

scientific article published on 12 November 2010

Prediction and classification of protein subcellular location-sequence-order effect and pseudo amino acid composition

article

Prediction of Enzyme Family Classes ⬇️

scientific article published on 01 March 2003

Prediction of G-protein-coupled receptor classes.

scientific article published in July 2005

Prediction of antimicrobial peptides based on sequence alignment and feature selection methods

scientific article

Prediction of beta-turns with learning machines.

scientific article published in May 2003

Prediction of body fluids where proteins are secreted into based on protein interaction network

scientific article

Prediction of membrane protein types by incorporating amphipathic effects

scientific article published in March 2005

Prediction of protease types in a hybridization space

scientific article published on 9 November 2005

Prediction of protein domain with mRMR feature selection and analysis

scientific article

Prediction of protein secondary structure content by artificial neural network.

scientific article

Prediction of protein signal sequences

scientific article

Prediction of protein signal sequences and their cleavage sites by statistical rulers

scientific article

Prediction of protein structural classes by support vector machines.

scientific article

Prediction of protein structure classes with pseudo amino acid composition and fuzzy support vector machine network.

scientific article

Prediction of protein subcellular location using hydrophobic patterns of amino acid sequence.

scientific article published on 11 September 2006

Prediction of protein subcellular locations by GO-FunD-PseAA predictor

scientific article published on August 2004

Prediction of the aquatic toxicity of aromatic compounds to tetrahymena pyriformis through support vector regression

scientific article published on 13 April 2017

Prediction of the tertiary structure of the beta-secretase zymogen

scientific article published in April 2002

Prediction protein structural classes with pseudo-amino acid composition: approximate entropy and hydrophobicity pattern

scientific article published on 15 September 2007

Progress in computational approach to drug development against SARS.

scientific article published on January 2006

Progress in protein structural class prediction and its impact to bioinformatics and proteomics

scientific article

Progress in structure-based drug design against influenza A virus

scientific article

ProtIdent: a web server for identifying proteases and their types by fusing functional domain and sequential evolution information

scientific article published on 5 September 2008

Pse-Analysis: a python package for DNA/RNA and protein/ peptide sequence analysis based on pseudo components and kernel methods

scientific article

Pse-in-One: a web server for generating various modes of pseudo components of DNA, RNA, and protein sequences

scientific article published on 9 May 2015

PseAAC: a flexible web server for generating various kinds of protein pseudo amino acid composition

scientific article

PseKNC-General: a cross-platform package for generating various modes of pseudo nucleotide compositions

scientific article

PseKNC: a flexible web server for generating pseudo K-tuple nucleotide composition

scientific article published on 13 April 2014

Pseudo nucleotide composition or PseKNC: an effective formulation for analyzing genomic sequences

scientific article published on 23 June 2015

Quat-2L: a web-server for predicting protein quaternary structural attributes

scientific article published on 11 February 2010

QuatIdent: a web server for identifying protein quaternary structural attribute by fusing functional domain and sequential evolution information

scientific article published on March 2009

RSARF: prediction of residue solvent accessibility from protein sequence using random forest method

scientific article

Recent Progress in Predicting Posttranslational Modification Sites in Proteins

scientific article published on 19 August 2015

Recent advances in QSAR and their applications in predicting the activities of chemical molecules, peptides and proteins for drug design

scientific article published on June 2008

Recent advances in computational studies on influenza a virus M2 proton channel

scientific article published on September 2012

Recent advances in predicting protein classification and their applications to drug development

scientific article published on January 2013

Recent novel high-tech researches in molecular biology

scientific article

Recent progress in protein subcellular location prediction

scientific article (publication date: November 2007)

Recent progresses in identifying nuclear receptors and their families

scientific article published on January 2013

Remote data retrieval for bioinformatics applications: an agent migration approach

scientific article (publication date: 2011)

Research/review: Insights into the mutation-induced dysfunction of arachidonic acid metabolism from modeling of human CYP2J2.

scientific article published on January 2014

Research/review: Structure and linkage disequilibrium analysis of adamantane resistant mutations in influenza virus m2 proton channel

scientific article

Role of the protein outside active site on the diffusion-controlled reaction of enzymes

scientific article published in 1982

Roles of L5-7 Loop in the Structure and Chaperone Function of SsHSP14.1 ⬇️

scientific article published on March 1, 2011

SCYPPred: a web-based predictor of SNPs for human cytochrome P450.

scientific article published in January 2012

SLLE for predicting membrane protein types.

scientific article published in January 2005

Screening for new agonists against Alzheimer's disease

scientific article published in September 2007

Selection of molecular descriptors with artificial intelligence for the understanding of HIV-1 protease peptidomimetic inhibitors-activity.

scientific article published in March 2005

Signal propagation in protein interaction network during colorectal cancer progression

scientific article published on 20 March 2013

Signal-3L: A 3-layer approach for predicting signal peptides

scientific article published on 31 August 2007

Signal-CF: a subsite-coupled and window-fusing approach for predicting signal peptides

scientific article published on 5 April 2007

Small molecular floribundiquinone B derived from medicinal plants inhibits acetylcholinesterase activity

scientific article published on 11 July 2017

Some illuminating remarks on molecular genetics and genomics as well as drug development

scientific article published on 01 January 2020

Some remarks on predicting multi-label attributes in molecular biosystems

scientific article published on 28 March 2013

Some remarks on protein attribute prediction and pseudo amino acid composition

scientific article published on 17 December 2010

Stochastic molecular descriptors for polymers. 4. Study of complex mixtures with topological indices of mass spectra spiral and star networks: The blood proteome case

article

Structural bioinformatics and its impact to biomedical science

scientific article published in August 2004

Structure of cytochrome p450s and personalized drug

scientific article published on January 2009

Support Vector Machines for Predicting Membrane Protein Types by Using Functional Domain Composition ⬇️

scientific article published on May 1, 2003

Support Vector Machines for predicting HIV protease cleavage sites in protein.

scientific article published in January 2002

Support vector machine for predicting alpha-turn types.

scientific article

Support vector machines for predicting the specificity of GalNAc-transferase.

scientific article published in January 2002

Support vector machines for prediction of protein signal sequences and their cleavage sites

scientific article published in January 2003

Support vector machines for prediction of protein subcellular location by incorporating quasi-sequence-order effect.

scientific article published in January 2002

Support vector machines for the classification and prediction of ?-turn types

scientific article published on 01 July 2002

The Nemertine Toxin Anabaseine and Its Derivative DMXBA (GTS-21): Chemical and Pharmacological Properties

scientific article

The computational model to predict accurately inhibitory activity for inhibitors towards CYP3A4.

scientific article published on 16 October 2010

Theoretical studies of Alzheimer's disease drug candidate 3-[(2,4-dimethoxy)benzylidene]-anabaseine (GTS-21) and its derivatives

scientific article published on 21 October 2005

Three new powerful oseltamivir derivatives for inhibiting the neuraminidase of influenza virus ⬇️

scientific article published on September 16, 2010

Twenty years of bioinformatics research for protease-specific substrate and cleavage site prediction: a comprehensive revisit and benchmarking of existing methods

Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.

scientific article published on 6 December 2008

Unified QSAR approach to antimicrobials. Part 3: first multi-tasking QSAR model for input-coded prediction, structural back-projection, and complex networks clustering of antiprotozoal compounds.

scientific article published on 29 April 2008

Using Functional Domain Composition and Support Vector Machines for Prediction of Protein Subcellular Location

scientific article published in Journal of Biological Chemistry

Using GO-PseAA predictor to identify membrane proteins and their types

scientific article published on February 2005

Using GO-PseAA predictor to predict enzyme sub-class.

scientific article

Using LogitBoost classifier to predict protein structural classes.

scientific article published on 25 July 2005

Using a new alignment kernel function to identify secretory proteins

scientific article published in January 2007

Using amphiphilic pseudo amino acid composition to predict enzyme subfamily classes

scientific article

Using deformation energy to analyze nucleosome positioning in genomes

article published in 2016

Using fourier spectrum analysis and pseudo amino acid composition for prediction of membrane protein types

scientific article published on 01 August 2005

Using functional domain composition to predict enzyme family classes.

scientific article published in January 2005

Using grey dynamic modeling and pseudo amino acid composition to predict protein structural classes

scientific article published on 01 September 2008

Using maximum entropy model to predict protein secondary structure with single sequence

scientific article

Using optimized evidence-theoretic K-nearest neighbor classifier and pseudo-amino acid composition to predict membrane protein types

scientific article published on 01 August 2005

Using protein-protein interaction network information to predict the subcellular locations of proteins in budding yeast

scientific article published on 01 June 2012

Using pseudo amino acid composition to predict protein structural classes: approached with complexity measure factor.

scientific article

Using stacked generalization to predict membrane protein types based on pseudo-amino acid composition

scientific article published on 16 May 2006

Using supervised fuzzy clustering to predict protein structural classes

scientific article

Virtual screening for SARS-CoV protease based on KZ7088 pharmacophore points

scientific article

Virus-PLoc: a fusion classifier for predicting the subcellular localization of viral proteins within host and virus-infected cells

scientific article published on February 2007

Virus-mPLoc: a fusion classifier for viral protein subcellular location prediction by incorporating multiple sites

scientific article published on October 2010

Weighted-support vector machines for predicting membrane protein types based on pseudo-amino acid composition.

scientific article published in June 2004

dRHP-PseRA: detecting remote homology proteins using profile-based pseudo protein sequence and rank aggregation

scientific article published on September 2016

iACP: a sequence-based tool for identifying anticancer peptides

scientific article published on March 2016

iAMP-2L: a two-level multi-label classifier for identifying antimicrobial peptides and their functional types

scientific article published on 6 February 2013

iATC-mHyb: a hybrid multi-label classifier for predicting the classification of anatomical therapeutic chemicals

scientific article published on 11 April 2017

iATC-mISF: a multi-label classifier for predicting the classes of anatomical therapeutic chemicals

scientific article

iCDI-PseFpt: identify the channel-drug interaction in cellular networking with PseAAC and molecular fingerprints

scientific article

iCar-PseCp: identify carbonylation sites in proteins by Monte Carlo sampling and incorporating sequence coupled effects into general PseAAC.

scientific article published on 02 May 2016

iDHS-EL: identifying DNase I hypersensitive sites by fusing three different modes of pseudo nucleotide composition into an ensemble learning framework

scientific article published on 8 April 2016

iDNA-Methyl: identifying DNA methylation sites via pseudo trinucleotide composition

scientific article published on 14 January 2015

iDNA-Prot: identification of DNA binding proteins using random forest with grey model

scientific article

iDNA-Prot|dis: identifying DNA-binding proteins by incorporating amino acid distance-pairs and reduced alphabet profile into the general pseudo amino acid composition

scientific article

iDNA6mA-PseKNC: Identifying DNA N6-methyladenosine sites by incorporating nucleotide physicochemical properties into PseKNC.

scientific article published on 19 January 2018

iDrug-Target: predicting the interactions between drug compounds and target proteins in cellular networking via benchmark dataset optimization approach

scientific article published on 16 December 2014

iEnhancer-2L: a two-layer predictor for identifying enhancers and their strength by pseudo k-tuple nucleotide composition

scientific article

iEzy-drug: a web server for identifying the interaction between enzymes and drugs in cellular networking

scientific article (publication date: 2013)

iGPCR-drug: a web server for predicting interaction between GPCRs and drugs in cellular networking

scientific article (publication date: 2013)

iHSP-PseRAAAC: Identifying the heat shock protein families using pseudo reduced amino acid alphabet composition

scientific article published on 10 June 2013

iHyd-PseAAC: predicting hydroxyproline and hydroxylysine in proteins by incorporating dipeptide position-specific propensity into pseudo amino acid composition

scientific article

iHyd-PseCp: Identify hydroxyproline and hydroxylysine in proteins by incorporating sequence-coupled effects into general PseAAC.

scientific article published on 14 June 2016

iKcr-PseEns: Identify lysine crotonylation sites in histone proteins with pseudo components and ensemble classifier

scientific article

iLoc-Animal: a multi-label learning classifier for predicting subcellular localization of animal proteins

scientific article published on 31 January 2013

iLoc-Euk: a multi-label classifier for predicting the subcellular localization of singleplex and multiplex eukaryotic proteins

scientific article (publication date: 30 March 2011)

iLoc-Gpos: a multi-layer classifier for predicting the subcellular localization of singleplex and multiplex Gram-positive bacterial proteins

scientific article published on January 2012

iLoc-Hum: using the accumulation-label scale to predict subcellular locations of human proteins with both single and multiple sites.

scientific article

iLoc-Plant: a multi-label classifier for predicting the subcellular localization of plant proteins with both single and multiple sites

scientific article published on 10 October 2011

iLoc-Virus: a multi-label learning classifier for identifying the subcellular localization of virus proteins with both single and multiple sites

scientific article published on 17 June 2011

iMethyl-PseAAC: identification of protein methylation sites via a pseudo amino acid composition approach

scientific article

iMiRNA-PseDPC: microRNA precursor identification with a pseudo distance-pair composition approach

scientific article published on 3 February 2015

iNR-Drug: predicting the interaction of drugs with nuclear receptors in cellular networking

scientific article published on 19 March 2014

iNR-PhysChem: a sequence-based predictor for identifying nuclear receptors and their subfamilies via physical-chemical property matrix

scientific article

iNitro-Tyr: prediction of nitrotyrosine sites in proteins with general pseudo amino acid composition

scientific article

iNuc-PseKNC: a sequence-based predictor for predicting nucleosome positioning in genomes with pseudo k-tuple nucleotide composition

scientific article published on 6 February 2014

iOri-Human: identify human origin of replication by incorporating dinucleotide physicochemical properties into pseudo nucleotide composition

scientific article

iPGK-PseAAC: Identify Lysine Phosphoglycerylation Sites in Proteins by Incorporating Four Different Tiers of Amino Acid Pairwise Coupling Information into the General PseAAC.

scientific article

iPPBS-Opt: A Sequence-Based Ensemble Classifier for Identifying Protein-Protein Binding Sites by Optimizing Imbalanced Training Datasets.

scientific article published on 19 January 2016

iPPI-Esml: An ensemble classifier for identifying the interactions of proteins by incorporating their physicochemical properties and wavelet transforms into PseAAC.

scientific article published on 20 April 2015

iPPI-PseAAC(CGR): Identify protein-protein interactions by incorporating chaos game representation into PseAAC

scientific article published on 09 October 2018

iPTM-mLys: identifying multiple lysine PTM sites and their different types

scientific article

iPhos-PseEn: identifying phosphorylation sites in proteins by fusing different pseudo components into an ensemble classifier

scientific article published on 13 June 2016

iPhos-PseEvo: Identifying Human Phosphorylated Proteins by Incorporating Evolutionary Information into General PseAAC via Grey System Theory

scientific article published on 12 May 2016

iPreny-PseAAC: identify C-terminal cysteine prenylation sites in proteins by incorporating two tiers of sequence couplings into PseAAC.

scientific article published on 19 April 2017

iPro54-PseKNC: a sequence-based predictor for identifying sigma-54 promoters in prokaryote with pseudo k-tuple nucleotide composition

scientific article

iPromoter-2L: a two-layer predictor for identifying promoters and their types by multi-window-based PseKNC.

scientific article published on 14 September 2017

iProt-Sub: a comprehensive package for accurately mapping and predicting protease-specific substrates and cleavage sites

iRNA-2methyl: Identify RNA 2'-O-methylation Sites by Incorporating Sequence-Coupled Effects into General PseKNC and Ensemble Classifier

scientific article published on 22 June 2017

iRNA-3typeA: Identifying Three Types of Modification at RNA's Adenosine Sites.

scientific article

iRNA-AI: identifying the adenosine to inosine editing sites in RNA sequences.

scientific article published on December 2016

iRNA-Methyl: Identifying N(6)-methyladenosine sites using pseudo nucleotide composition

scientific article published on 24 August 2015

iRNA-PseColl: Identifying the Occurrence Sites of Different RNA Modifications by Incorporating Collective Effects of Nucleotides into PseKNC.

scientific article

iRNA-PseU: Identifying RNA pseudouridine sites

scientific article published on January 2016

iRNAm5C-PseDNC: identifying RNA 5-methylcytosine sites by incorporating physical-chemical properties into pseudo dinucleotide composition

scientific article published on 17 April 2017

iROS-gPseKNC: Predicting replication origin sites in DNA by incorporating dinucleotide position-specific propensity into general pseudo nucleotide composition

scientific article published on 27 April 2016

iRSpot-EL: identify recombination spots with an ensemble learning approach

scientific article

iRSpot-Pse6NC: Identifying recombination spots in Saccharomyces cerevisiae by incorporating hexamer composition into general PseKNC.

scientific article published on 22 May 2018

iRSpot-TNCPseAAC: identify recombination spots with trinucleotide composition and pseudo amino acid components

scientific article published on 24 January 2014

iSNO-AAPair: incorporating amino acid pairwise coupling into PseAAC for predicting cysteine S-nitrosylation sites in proteins

scientific article (publication date: 2013)

iSNO-PseAAC: predict cysteine S-nitrosylation sites in proteins by incorporating position specific amino acid propensity into pseudo amino acid composition

scientific article

iSuc-PseOpt: Identifying lysine succinylation sites in proteins by incorporating sequence-coupling effects into pseudo components and optimizing imbalanced training dataset

scientific article published on 23 December 2015

iTIS-PseTNC: a sequence-based predictor for identifying translation initiation site in human genes using pseudo trinucleotide composition

scientific article published on 10 July 2014

iUbiq-Lys: prediction of lysine ubiquitination sites in proteins by extracting sequence evolution information via a gray system model

scientific article published on 6 November 2014

pLoc-mAnimal: predict subcellular localization of animal proteins with both single and multiple sites

scientific article published on 24 July 2017

pLoc-mEuk: Predict subcellular localization of multi-label eukaryotic proteins by extracting the key GO information into general PseAAC.

scientific article published on 14 August 2017

pLoc-mGneg: Predict subcellular localization of Gram-negative bacterial proteins by deep gene ontology learning via general PseAAC.

scientific article

pLoc-mHum: predict subcellular localization of multi-location human proteins via general PseAAC to winnow out the crucial GO information

scientific article published on 2 November 2017

pLoc-mPlant: predict subcellular localization of multi-location plant proteins by incorporating the optimal GO information into general PseAAC.

scientific article published on 12 July 2017

pLoc-mVirus: Predict subcellular localization of multi-location virus proteins via incorporating the optimal GO information into general PseAAC.

scientific article published on 17 July 2017

pRNAm-PC: Predicting N(6)-methyladenosine sites in RNA sequences via physical-chemical properties

scientific article published on 31 December 2015

pSuc-Lys: Predict lysine succinylation sites in proteins with PseAAC and ensemble random forest approach

scientific article published on 22 January 2016

pSumo-CD: predicting sumoylation sites in proteins with covariance discriminant algorithm by incorporating sequence-coupled effects into general PseAAC.

scientific article published on 26 June 2016

repDNA: a Python package to generate various modes of feature vectors for DNA sequences by incorporating user-defined physicochemical properties and sequence-order effects

scientific article published on 10 December 2014

repRNA: a web server for generating various feature vectors of RNA sequences.

scientific article published on 18 June 2015

Paulina is supported by:

About Paulina

Help