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List of works by Cynthia Wolberger

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SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

scientific article
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

scientific article
Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme

scientific article
The biochemistry of sirtuins.

scientific article
A standard reference frame for the description of nucleic acid base-pair geometry.

scientific article
The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA

scientific article
New insights into ubiquitin E3 ligase mechanism

scientific article published on April 1, 2014
Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme

scientific article (publication date: 18 March 2005)
Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer

scientific article
Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation

scientific article (publication date: October 2006)
Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation

scientific article
Recognition of specific DNA sequences.

scientific article
Regulated nucleosome mobility and the histone code.

scientific article
The mechanism of OTUB1-mediated inhibition of ubiquitination

scientific article
Structure of a Sir2 enzyme bound to an acetylated p53 peptide

scientific article
Structural Insights into the Assembly and Function of the SAGA Deubiquitinating Module

scientific article
Structure of HoxA9 and Pbx1 bound to DNA: Hox hexapeptide and DNA recognition anterior to posterior

scientific article
Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

scientific article
Structural studies of Ets-1/Pax5 complex formation on DNA

scientific article
Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH

scientific article
A conserved catalytic residue in the ubiquitin-conjugating enzyme family.

scientific article published on October 2003
How does the histone code work?

scientific article
RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage.

scientific article
Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism.

scientific article published on 21 October 2008
A core nucleosome surface crucial for transcriptional silencing

scientific article published on 16 September 2002
N-lysine propionylation controls the activity of propionyl-CoA synthetase

scientific article published on 7 August 2007
Structure of a phage 434 Cro/DNA complex

scientific article published in Nature
The Structure and Conformation of Lys63-Linked Tetraubiquitin

scientific article
Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1

scientific article
Structural basis for the mechanism and regulation of Sir2 enzymes.

scientific article published in March 2004
Structural basis for histone H2B deubiquitination by the SAGA DUB module.

scientific article
Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD+ and Acetylated Peptide

scientific article published on 01 August 2006
Structural Insights into Intermediate Steps in the Sir2 Deacetylation Reaction

scientific article
The Substrate Specificity of Sirtuins

scientific article published on 18 April 2016
E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

scientific article
The Structural Basis of Sirtuin Substrate Affinity†,‡

scientific article published on 01 June 2006
Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships

scientific article
Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia

scientific article published on 3 November 2014
Preprints for the life sciences

scientific article
A spectrophotometric assay for conjugation of ubiquitin and ubiquitin-like proteins.

scientific article
A Hoogsteen base pair embedded in undistorted B-DNA.

scientific article
Combinatorial transcription factors.

scientific article
Characterization of the N-terminal Domain of the Yeast Transcriptional Repressor Tup1

scientific article published in Journal of Biological Chemistry
SIR2 family of NAD(+)-dependent protein deacetylases.

scientific article
A conserved asparagine has a structural role in ubiquitin-conjugating enzymes

scientific article
The 1.6 A crystal structure of the AraC sugar-binding and dimerization domain complexed with D-fucose

scientific article
A Tunable Brake for HECT Ubiquitin Ligases

scientific article published in May 2017
The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3

scientific article
Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera

scientific article
A new chapter in the transcription SAGA.

scientific article published on 18 October 2011

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