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List of works by Kai Wucherpfennig

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

article

A functional and structural basis for TCR cross-reactivity in multiple sclerosis

scientific article

A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing

scientific article published on 4 January 2018

A membrane-proximal tetracysteine motif contributes to assembly of CD3deltaepsilon and CD3gammaepsilon dimers with the T cell receptor.

scientific article published on 5 October 2006

ATIM-32. PERSONALIZED NEOANTIGEN-TARGETING VACCINE GENERATES ROBUST SYSTEMIC AND INTRATUMORAL T CELL RESPONSES IN GLIOBLASTOMA (GBM) PATIENTS

Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins

scientific article

An immunogenic personal neoantigen vaccine for patients with melanoma

scientific article

Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity.

scientific article

Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells

scientific article published on 20 February 2020

B cell homeostasis and follicle confines are governed by fibroblastic reticular cells

scientific article

Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling

scientific article published on 26 July 2016

Common themes in the assembly and architecture of activating immune receptors

scientific article published on November 2007

Convergence on a distinctive assembly mechanism by unrelated families of activating immune receptors.

scientific article

Corrigendum: An immunogenic personal neoantigen vaccine for patients with melanoma

scientific article published in Nature

Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection ⬇️

scientific article published on December 21, 2012

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

scientific article published in April 2018

Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient

scientific article published on 20 February 2020

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response

scientific article published on 01 March 2019

Ex vivo characterization and isolation of rare memory B cells with antigen tetramers

scientific article

HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide

scientific article

Immunotherapy for glioblastoma: on the sidelines or in the game?

scientific article published in November 2017

Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans

scientific article

Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain

scientific article

MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets

scientific article published on 13 May 2022

Mechanical checkpoint regulates monocyte differentiation in fibrotic niches

scientific article published in 2022

Mechanisms of peptide repertoire selection by HLA-DM

scientific article published on 05 July 2013

MicroRNA expression profiling identifies activated B cell status in chronic lymphocytic leukemia cells

scientific article

Molecular mechanisms for the assembly of the T cell receptor-CD3 complex.

scientific article published on April 2004

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

scientific article published on 19 December 2018

Positively selecting peptides: their job does not end in the thymus

scientific article published on 01 November 2009

Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity

scientific article published on 05 September 2018

Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

scientific article

Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway.

scientific article

Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters

scientific article published on 05 February 2020

Response multilayered control of T cell receptor phosphorylation

scientific article published on September 2010

Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4+ and CD8+ T cell responses

scientific article published on 8 January 2018

Stoichiometry of the T-cell receptor-CD3 complex and key intermediates assembled in the endoplasmic reticulum

scientific article

Structural biology of the T-cell receptor: insights into receptor assembly, ligand recognition, and initiation of signaling

scientific article

Systematic investigation of cytokine signaling activity at the tissue and single-cell levels

scientific article published on 30 September 2021

Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation

scientific article

The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure.

scientific article

The assembly of diverse immune receptors is focused on a polar membrane-embedded interaction site

scientific article

The organizing principle in the formation of the T cell receptor-CD3 complex.

scientific article

The solvent-inaccessible Cys67 residue of HLA-B27 contributes to T cell recognition of HLA-B27/peptide complexes.

scientific article

The structural basis for intramembrane assembly of an activating immunoreceptor complex

scientific article

The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor

scientific article

Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor

scientific article

Unusual features of self-peptide/MHC binding by autoimmune T cell receptors

scientific article

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