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List of works by Stuart Yuspa

A PMLRARA transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis ⬇️

scientific article published on September 1, 2003

A comparison of interfollicular and hair follicle derived cells as targets for the v-rasHa oncogene in mouse skin carcinogenesis

scientific article published on June 1991

A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes ⬇️

scientific article published on February 1, 1991

A humanized stromal bed is required for engraftment of isolated human primary squamous cell carcinoma cells in immunocompromised mice

scientific article published on 6 October 2011

A model for initiated mouse skin: suppression of papilloma but not carcinoma formation by normal epidermal cells in grafts on athymic nude mice ⬇️

scientific article published on March 15, 1992

A novel DLX3-PKC integrated signaling network drives keratinocyte differentiation

scientific article published on 10 February 2017

A pilot project in molecular cancer epidemiology: determination of benzo[a]pyrene — DNA adducts in animal and human tissues by immunoassays ⬇️

scientific article published on January 1, 1982

A procedure for the culture of hair follicles as functionally intact organoids

scientific article published on 01 October 1988

A splice variant of alpha 6 integrin is associated with malignant conversion in mouse skin tumorigenesis

scientific article

A survey of transformation markers in differentiating epidermal cell lines in culture.

scientific article published on December 1980

Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension

scientific article

Aberrant differentiation in mouse skin carcinogenesis

scientific article published on January 1988

Aberrant expression during two-stage mouse skin carcinogenesis of a type I 47-kDa keratin, K13, normally associated with terminal differentiation of internal stratified epithelia.

scientific article

Activation of cutaneous protein kinase C alpha induces keratinocyte apoptosis and intraepidermal inflammation by independent signaling pathways

scientific journal article

Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta

scientific article

Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion

scientific article published on September 1991

Activator protein 1 transcription factors are fundamental to v-rasHa-induced changes in gene expression in neoplastic keratinocytes

article

Activator protein-1 activity regulates epithelial tumor cell identity.

scientific article published in August 2006

Activity of diverse tumor promoters in a keratinocyte co-culture model of initiated epidermis

scientific article published on November 1, 1992

Acute or chronic topical retinoic acid treatment of human skin in vivo alters the expression of epidermal transglutaminase, loricrin, involucrin, filaggrin, and keratins 6 and 13 but not keratins 1, 10, and 14

scientific article published on March 1, 1992

Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis ⬇️

scientific article published on June 1, 1991

Alterations in epidermal functions resulting from exposure to initiators and promoters of carcinogenesis.

scientific article published on January 1983

Alterations in murine keratinocyte differentiation induced by activated rasHa genes are mediated by protein kinase C-alpha.

scientific article published in December 1994

Alterations in the biology and biochemistry of keratinocytes induced by the ras oncogene

scientific article published on January 1, 1992

Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro.

scientific article published in May 1974

Altered glycoprotein synthesis in mouse epidermal cells treated with retinyl acetate in vitro.

scientific article published in May 1974

Altered growth and differentiation of cultured mouse epidermal cells infected with oncogenic retrovirus: contrasting effects of viruses and chemicals ⬇️

scientific article published on December 1, 1983

Altered regulation of TGF-beta 1 and TGF-alpha in primary keratinocytes and papillomas expressing v-Ha-ras

scientific article published on January 1991

Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors ⬇️

scientific article published on November 1, 1991

Aluminum fluoride stimulates inositol phosphate metabolism and inhibits expression of differentiation markers in mouse keratinocytes ⬇️

scientific article published on July 1, 1991

An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue

scientific article published on October 1986

An antibody to p53 recognizes soluble keratins in epidermal keratinocyte cultures under differentiating, but not proliferating, conditions

scientific article published on 01 October 1997

Analysis of phospholipid metabolism in murine keratinocytes transformed by the v-ras oncogene: relationship of phosphatidylinositol turnover and cytokine stimulation to the transformed phenotype

scientific article published on December 1, 1992

Analysis of the rasH oncogene and its p21 product in chemically induced skin tumors and tumor-derived cell lines

scientific article published on December 1987

Analysis of v‐Ha‐ras and v‐fos oncogene transduction into a mouse epidermal cell line with “initiated” phenotype in culture but normal skin phenotype in vivo ⬇️

scientific article published on June 1, 1995

Antibodies elicited against cis-diamminedichloroplatinum(II)-modified DNA are specific for cis-diamminedichloroplatinum(II)-DNA adducts formed in vivo and in vitro

scientific article

Antisense suppression of the chloride intracellular channel family induces apoptosis, enhances tumor necrosis factor {alpha}-induced apoptosis, and inhibits tumor growth.

scientific article published on January 2005

Application of cantharidin or 12-O-tetradecanoylphorbol-13-acetate on mouse epidermis induces a cell population shift that causes altered keratin distribution

scientific article published on September 1994

Association of DNA strand breaks with accelerated terminal differentiation in mouse epidermal cells exposed to tumor promoters

scientific article published on October 1985

Association of resistance to terminal differentiation with initiation of carcinogenesis in adult mouse epidermal cells.

scientific article

Autocrine transforming growth factor alpha is dispensible for v-rasHa-induced epidermal neoplasia: potential involvement of alternate epidermal growth factor receptor ligands

scientific article published on 01 May 1995

Benzo(a)pyrene-DNA adduct formation and removal in mouse epidermis in vivo and in vitro: relationship of DNA binding to initiation of skin carcinogenesis ⬇️

scientific article published on September 1, 1984

Benzo[alpha]pyrene diol epoxide I binds to DNA at replication forks

scientific article

Biochemical Evidence for Keratinization by Mouse Epidermal Cells in Culture ⬇️

scientific article published on June 30, 1978

Biological activity of the bryostatin analog Merle 23 on mouse epidermal cells and mouse skin.

scientific article published on 9 February 2016

Biomonitoring of cisplatin-DNA adducts in cancer patients receiving cisplatin chemotherapy

scientific article published on 01 January 1986

Bryostatin 1 protects protein kinase C-delta from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester-induced differentiation

scientific article published on 01 November 1994

Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin

scientific article

CLIC4 and Schnurri-2: a dynamic duo in TGF-beta signaling with broader implications in cellular homeostasis and disease

scientific article

CLIC4 is a tumor suppressor for cutaneous squamous cell cancer.

scientific article published in March 2012

CLIC4 mediates and is required for Ca2+-induced keratinocyte differentiation

scientific article

CLIC4 regulates TGF-β-dependent myofibroblast differentiation to produce a cancer stroma

scientific article published on 18 February 2013

CLIC4, an intracellular chloride channel protein, is a novel molecular target for cancer therapy.

scientific article

CLIC4, skin homeostasis and cutaneous cancer: surprising connections

scientific article published on August 2007

CRE DNA binding proteins bind to the AP-1 target sequence and suppress AP-1 transcriptional activity in mouse keratinocytes

scientific article published on February 1999

CXCR2 ligands and G-CSF mediate PKCalpha-induced intraepidermal inflammation

scientific article

Calcium regulation of growth and differentiation of mouse epidermal cells in culture ⬇️

scientific article published on January 1, 1980

Cancer. An anchor for tumor cell invasion.

scientific article

Cell autonomous or systemic EGFR blockade alters the immune-environment in squamous cell carcinomas

scientific article

Cell protein cross-linking by erbstatin and related compounds.

scientific article

Cellular and molecular changes during chemical carcinogenesis in mouse skin cells.

scientific article

Cellular and molecular mechanisms of carcinogenesis in lining epithelia

scientific article published on January 1986

Changes in Photo-Aged Human Skin Following Topical Application of All-Trans Retinoic Acid ⬇️

scientific article published on 01 November 1990

Changes in inositol phosphate metabolism are associated with terminal differentiation and neoplasia in mouse keratinocytes

scientific article published on September 1991

Characterization of a novel cyclin-dependent kinase 1 inhibitor, BMI-1026 ⬇️

scientific article published on November 1, 2003

Characterization of bullous pemphigoid antigen: a unique basement membrane protein of stratified squamous epithelia

scientific article published on 01 June 1981

Chelation of intracellular Ca2+ inhibits murine keratinocyte differentiation in vitro

scientific article

Chemical Carcinogenesis Studies in Mouse Epidermal Cell Cultures ⬇️

scientific article published on January 1, 1980

Chemical carcinogenesis: from animal models to molecular models in one decade

scientific article published on January 1988

Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15

scientific article

Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets

scientific article

Cholesterol sulfate activates multiple protein kinase C isoenzymes and induces granular cell differentiation in cultured murine keratinocytes.

scientific article published on December 1995

Clonal growth of mouse epidermal cells in medium with reduced calcium concentration

scientific article published on 01 February 1981

Comparison of octahydromezerein and mezerein as protein kinase C activators and as mouse skin tumor promoters.

scientific article published in October 1989

Comparison of two-stage epidermal carcinogenesis initiated by 7,12-dimethylbenz(a)anthracene or N-methyl-N'-nitro-N-nitrosoguanidine in newborn and adult SENCAR and BALB/c mice.

scientific article published in March 1981

Consequences of exposure to initiating levels of carcinogens in vitro and in vivo: altered differentiation and growth, mutations, and transformation

scientific article

Contrasting actions of staurosporine, a protein kinase C inhibitor, on human neutrophils and primary mouse epidermal cells

scientific article published on 01 August 1988

Contrasting duration of inhibition of cell-cell communication in primary mouse epidermal cells by phorbol 12,13-dibutyrate and by bryostatin 1

scientific article published on 01 January 1988

Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C ⬇️

scientific article published on January 1, 1993

Correlation of initiating potency of skin carcinogens with potency to induce resistance to terminal differentiation in cultured mouse keratinocytes

scientific article published on May 1985

Critical aspects of initiation, promotion, and progression in multistage epidermal carcinogenesis

scientific article published on January 1993

Cross-talk between epidermal growth factor receptor and protein kinase C during calcium-induced differentiation of keratinocytes

scientific article published on June 2000

Cultivation and characterization of cells derived from mouse skin papillomas induced by an initiation-promotion protocol

scientific article published on June 1986

Cultivation of murine hair follicles as organoids in a collagen matrix

scientific article published on 01 October 1987

Cutaneous chemical carcinogenesis

scientific article

Cutaneous chemical carcinogenesis: past, present, and future

scientific article published on July 1976

Cutaneous retinoic acid levels determine hair follicle development and downgrowth

scientific article

Cytogenetic evidence for gene amplification in mouse skin carcinogenesis.

scientific article published in July 1986

Cytogenetic profile of mouse skin tumors induced by the viral Harvey-ras gene.

scientific article

DNA adduct formation and removal in N-acetoxy-2-acetylaminofluorene-exposed cultured cells and in organs from rats fed 2-acetylaminofluorene

scientific article published on 01 January 1983

DNA adducts of cisplatin and carboplatin in tissues of cancer patients

scientific article published on 01 January 1988

DNA adducts of cisplatin in nucleated peripheral blood cells and tissues of cancer patients

scientific article published on 01 January 1987

Defects in transforming growth factor-beta signaling cooperate with a Ras oncogene to cause rapid aneuploidy and malignant transformation of mouse keratinocytes

scientific article published on December 1999

Definition by specific antisense oligonucleotides of a role for protein kinase C alpha in expression of differentiation markers in normal and neoplastic mouse epidermal keratinocytes

scientific article published on January 1997

Detection and quantitation of acetylated and deacetylated N-2-fluorenylacetamide-DNA adducts by radioimmunoassay

scientific article published on December 1981

Detection of carcinogen-DNA adducts by radiommunoassay

scientific article published on November 10, 1977

Detection of differential fetal and adult expression of chloride intracellular channel 4 (CLIC4) protein by analysis of a green fluorescent protein knock-in mouse line.

scientific article

Detection of pemphigoid antigen, pemphigus antigen, and keratin filaments by indirect immunofluorescence in cultured human epidermal cells

scientific article published on 01 August 1980

Development of a rapid approach to identification of tyrosine phosphorylation sites: application to PKC delta phosphorylated upon activation of the high affinity receptor for IgE in rat basophilic leukemia cells

scientific article

Development of an in vitro analogue of initiated mouse epidermis to study tumor promoters and antipromoters

scientific article published on August 1990

Development of an in vitro model to study carcinogen-induced neoplastic progression of initiated mouse epidermal cells ⬇️

scientific article published on June 1, 1992

Development of murine epidermal cell lines which contain an activated rasHa oncogene and form papillomas in skin grafts on athymic nude mouse hosts

scientific article published on January 1988

Differences in the regulation of intracellular calcium in normal and neoplastic keratinocytes are not caused by ras gene mutations

scientific article published on August 1991

Differences in the regulation of phosphatidylinositol-specific phospholipase C in normal and neoplastic keratinocytes

scientific article

Different levels of v-Ha-ras p21 expression in primary keratinocytes transformed with Harvey sarcoma virus correlate with benign versus malignant behavior

scientific article published in January 1993

Differential regulation by anti-tumor-promoting 12-deoxyphorbol-13-phenylacetate reveals distinct roles of the classical and novel protein kinase C isozymes in biological responses of primary mouse keratinocytes.

scientific article published in February 1995

Differential regulation of integrins and extracellular matrix binding in epidermal differentiation and squamous tumor progression

scientific article

Differential retinoic acid inhibition of ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate and by germicidal ultraviolet light.

scientific article published in January 1981

Differentiation of cultured human epidermal keratinocytes at high cell densities is mediated by endogenous activation of the protein kinase C signaling pathway.

scientific article published in November 1998

Differentiation of mouse keratinocytes is accompanied by PKC-dependent changes in AP-1 proteins

scientific article

Dimethyl sulfoxide-induced enhancement of 7,12-dimethylbenz(a)anthracene metabolism and DNA binding in differentiating mouse epidermal cell cultures

scientific article published on 01 March 1976

Direct quantification of polo-like kinase 1 activity in cells and tissues using a highly sensitive and specific ELISA assay

scholarly article

Dissociation of tumor promoter-stimulated ornithine decarboxylase activity and DNA synthesis in mouse epidermis in vivo and in vitro by fluocinolone acetonide, a tumor-promotion inhibitor ⬇️

scientific article published on September 1, 1977

Divergent responses in epidermal basal cells exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate ⬇️

scientific article published on June 1, 1982

Dynamic aspects of the supramolecular organization of intermediate filament networks in cultured epidermal cells

scientific article published on 01 January 1982

EGFR enhances early healing after cutaneous incisional wounding

scientific article published on 01 November 2004

EGFR regulates the expression of keratinocyte-derived granulocyte/macrophage colony-stimulating factor in vitro and in vivo

scientific article published on 5 November 2009

Early signals for keratinocyte differentiation: role of Ca2+-mediated inositol lipid metabolism in normal and neoplastic epidermal cells

scientific article published on June 1988

Effect of a tyrosine 155 to phenylalanine mutation of protein kinase cdelta on the proliferative and tumorigenic properties of NIH 3T3 fibroblasts

scientific article

Effect of culture conditions, cell type, and species of origin on the distribution of acetylated and deacetylated deoxyguanosine C-8 adducts of N-acetoxy-2-acetylaminofluorene.

scientific article published in November 1980

Effect of retinoic acid on cornified envelope formation: difference between spontaneous envelope formation in vivo or in vitro and expression of envelope competence

scientific article

Effects of Tumor Promoters and Steroidal Anti-inflammatory Agents on Skin of Newborn Mice In Vivo and In Vitro2 ⬇️

scientific article published on 01 February 1978

Elevating CLIC4 in Multiple Cell Types Reveals a TGF- Dependent Induction of a Dominant Negative Smad7 Splice Variant

scientific article

Enhanced malignant conversion of benign mouse skin tumors by cisplatin.

scientific article published in May 1990

Epidermal cell culture

scientific article published on 01 September 1980

Epidermal growth factor receptor ligands regulate keratin 8 expression in keratinocytes, and transforming growth factor alpha mediates the induction of keratin 8 by the v-rasHa oncogene ⬇️

scientific article published on April 1, 1993

Evaluation of platinum-DNA adduct levels relative to known prognostic variables in a cohort of ovarian cancer patients

scientific article published on 01 April 1990

Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta.

scientific article published in December 1993

Expression of interferon-beta is associated with growth arrest of murine and human epidermal cells

scientific article published on 01 May 1999

Expression of keratin genes in mouse epidermis and normal and malignantly transformed epidermal cells in culture.

scientific article published in July 1983

Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro

scientific article

Expression of the BNLF-1 oncogene of Epstein-Barr virus in the skin of transgenic mice induces hyperplasia and aberrant expression of keratin 6 ⬇️

scientific article published on June 29, 1990

Expression of transfected DNA by primary murine keratinocytes

scientific article published on August 1988

Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion.

scientific article published on 21 May 2007

Extracellular matrix receptors and mouse skin carcinogenesis: altered expression linked to appearance of early markers of tumor progression ⬇️

scientific article published on May 15, 1992

FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin

scientific article published on 01 November 1993

Factors influencing calcium-induced terminal differentiation in cultured mouse epidermal cells.

scientific article published in September 1983

Factors mediating the interactions between epidermal and dermal cells in skin grafts that might be important for hair follicle development.

scientific article published on May 1995

Formation and removal of specific acetylaminofluorene-DNA adducts in mouse and human cells measured by radioimmunoassay ⬇️

scientific article published on April 1, 1979

Frequent codon 12 Ki-ras mutations in mouse skin tumors initiated by N-methyl-N'-nitro-N-nitrosoguanidine and promoted by mezerein.

scientific article published in April 2000

Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation ⬇️

scientific article published on July 15, 1997

Gene from a psoriasis susceptibility locus primes the skin for inflammation

scientific article

Genetic ablation of cyclooxygenase-2 in keratinocytes produces a cell-autonomous defect in tumor formation

scientific article

Genetic ablation of epidermal EGFR reveals the dynamic origin of adverse effects of anti-EGFR therapy.

scientific article

Genetic deletion of p21WAF1 enhances papilloma formation but not malignant conversion in experimental mouse skin carcinogenesis

scientific article published on 01 May 1999

Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development

scientific article published on June 1997

Genomic structure and promoter analysis of PKC-delta

scientific article

Germicidal ultraviolet light induces ornithine decarboxylase in mouse epidermal cells and modifies the induction caused by phorbol ester tumor promoters

scientific article published on 01 August 1980

Growth and Differentiation of Mouse Epidermal Cells in Culture: Effects of Extracellular Calcium ⬇️

scientific article published on January 1, 1980

Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination

scientific article published on December 1990

HIF-1alpha regulates epithelial inflammation by cell autonomous NFkappaB activation and paracrine stromal remodeling

scientific article published on 16 January 2008

Hair follicle development and hair growth from defined cell populations grafted onto nude mice

scientific article published on May 1995

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4

scientific article published on 31 December 2019

Heterogeneity of [3H]phorbol 12,13-dibutyrate binding in primary mouse keratinocytes at different stages of maturation.

scientific article published in November 1985

Highly homologous hS100A15 and hS100A7 proteins are distinctly expressed in normal breast tissue and breast cancer

scientific article

Hyperphosphorylation of cytokeratins by okadaic acid class tumor promoters in primary human keratinocytes ⬇️

scientific article published on March 1, 1993

Identification and characterization of tumor-initiating cells in human primary cutaneous squamous cell carcinoma

scientific article

Identification of control elements 3' to the human keratin 1 gene that regulate cell type and differentiation-specific expression ⬇️

scientific article published on January 5, 1993

Identification of differentially expressed genes in chemically induced skin tumors

scientific article published on September 1997

Identification of filaggrin in cultured mouse keratinocytes and its regulation by calcium

scientific article published on 01 July 1983

Immortalized Rat Whisker Dermal Papilla Cells Cooperate with Mouse Immature Hair Follicle Buds to Activate Type IV Procollagenases in Collagen Matrix Coculture: Correlation with Ability to Promote Hair Follicle Development in Nude Mouse Grafts ⬇️

scientific article published on August 1, 1995

In Vitro Cultivation of a Chemically Induced Epidermal Carcinoma: Establishment of Three Cell Lines and Isolation of Murine Leukemia Virus ⬇️

scientific article published on June 1, 1973

In Vitro Neoplastic Transformation of Mouse Skin Cells: Morphology and Ultrastructure of Cells and Tumors ⬇️

scientific article published on June 1, 1974

In vitro comparisons of SENCAR and BALB/c primary epidermal cells

scientific article

In vivo regulation of murine hair growth: insights from grafting defined cell populations onto nude mice

scientific article published on July 1993

Increased retinoic acid levels through ablation of Cyp26b1 determine the processes of embryonic skin barrier formation and peridermal development

scientific journal article

Indirect immunofluorescent localization of benzo[a]pyrene adducted to nucleic acids in cultured mouse keratinocyte nuclei

scientific article published on 01 January 1982

Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation.

scientific article published on 2 April 2012

Inducible cutaneous inflammation reveals a protumorigenic role for keratinocyte CXCR2 in skin carcinogenesis

scientific article

Induction and autocrine receptor binding of transforming growth factor-beta 2 during terminal differentiation of primary mouse keratinocytes

scientific article published on January 1990

Induction of common patterns of polypeptide synthesis and phosphorylation by calcium and 12-O-tetradecanoylphorbol-13-acetate in mouse epidermal cell culture

scientific article

Induction of papillomas with a high probability of conversion to malignancy

scientific article published in November 1985

Induction of specific protein synthesis by phorbol esters in mouse epidermal cell culture ⬇️

scientific article published on June 1, 1981

Inhibition of 12-O-tetradecanoylphorbol-13-acetate induction of epidermal transglutaminase activity by protease inhibitors

scientific article published on 01 September 1983

Inhibition of calcium-induced terminal differentiation of epidermal cells by ouabain and A23187.

scientific article published on January 1983

Inhibition of epidermal terminal differentiation and tumour promotion by retinoids.

scientific article published in January 1985

Inhibition of tumor formation from grafted murine papilloma cells by treatment of grafts with staurosporine, an inducer of squamous differentiation.

scientific article published in February 1993

Inhibitors of the intracellular Ca(2+)-ATPase in cultured mouse keratinocytes reveal components of terminal differentiation that are regulated by distinct intracellular Ca2+ compartments.

scientific article

Inhibitory Effect of Pyridoxine Deficiency on Growth of a Transplanted Tumor in Rats

scientific article published in November 1966

Initiator and promoter induced specific changes in epidermal function and biological potential ⬇️

scientific article published on January 1, 1981

Interacting signaling pathways in the pathogenesis of squamous cell carcinoma.

scientific article

Interaction of epidermal growth factor with basal and differentiating epidermal cells of mice resistant and sensitive to carcinogenesis ⬇️

scientific article published on June 1, 1984

Intracellular calcium alterations in response to increased external calcium in normal and neoplastic keratinocytes

scientific article

Intracellular chloride channels: critical mediators of cell viability and potential targets for cancer therapy

scientific article

Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta

scientific article published in March 2000

Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice

scientific article published on 01 January 2008

Keratin expression in mouse epidermal tumors

scientific article published on January 1989

Keratin gene expression in mouse epidermis and cultured epidermal cells ⬇️

scientific article published on February 1, 1983

Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate

scientific article

Keratinocyte differentiation is associated with changes in the expression and regulation of phospholipase C isoenzymes

scientific article

Keratinocyte growth factor receptor ligands induce transforming growth factor alpha expression and activate the epidermal growth factor receptor signaling pathway in cultured epidermal keratinocytes.

scientific article published on December 1994

Keratinocyte p38δ loss inhibits Ras-induced tumor formation, while systemic p38δ loss enhances skin inflammation in the early phase of chemical carcinogenesis in mouse skin.

scientific article published on 8 March 2015

Keratinocytes blocked in phorbol ester-responsive early stage of terminal differentiation by sarcoma viruses

scientific article

Local anesthetics inhibit induction of ornithine decarboxylase by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate

scientific article

Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion ⬇️

scientific article published on July 1, 1993

Loss of retinoic acid receptors in mouse skin and skin tumors is associated with activation of the ras(Ha) oncogene and high risk for premalignant progression.

scientific article published on November 1996

Loss of syndecan-1 is associated with malignant conversion in skin carcinogenesis

scientific article published on April 2010

MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis.

scientific article published on 21 June 2016

Magnesium and phosphate enrichment of culture medium stimulates the proliferation of epidermal cells from newborn and adult mice

scientific article published on June 1990

Maintenance of human skin on nude mice for studies of chemical carcinogenesis ⬇️

scientific article published on April 1, 1979

Malignant conversion and metastasis of mouse skin tumors: a comparison of SENCAR and CD-1 mice

scientific article

Malignant conversion of mouse skin tumours is increased by tumour initiators and unaffected by tumour promoters

scientific article published in Nature

Malignant conversion of murine squamous papilloma cell lines by transfection with the fos oncogene

scientific article published in January 1988

Measurement of benzo(a)pyrene-DNA adducts by enzyme immunoassays and radioimmunoassay

scientific article published on 01 March 1981

Mechanisms of initiation and promotion in mouse epidermis

scientific article published on January 1, 1984

Mechanisms of transformation and promotion of mouse epidermal cells.

scientific article

Milestones in skin carcinogenesis: the biology of multistage carcinogenesis

scientific article

Mode of action of retinol. Involvement in glycosylation reactions of cultured mouse epidermal cells.

scientific article published on May 1979

Modeling the transcriptional consequences of epidermal growth factor receptor ablation in Ras-initiated squamous cancer

scientific article published on 8 November 2011

Modulation of Hair Follicle Cell Proliferation and Collagenolytic Activity by Specific Growth Factorsa ⬇️

scientific article published on December 26, 1991

Modulation of terminal differentiation and responses to tumor promoters by retinoids in mouse epidermal cell cultures

scientific article published on February 1981

Modulation of tissue and epidermal transglutaminases in mouse epidermal cells after treatment with 12-O-tetradecanoylphorbol-13-acetate and/or retinoic acid in vivo and in culture

scientific article published in January 1988

Molecular and cellular basis for tumor promotion in mouse skin

scientific article published on 01 January 1983

Molecular cloning of mouse epidermal cystatin A and detection of regulated expression in differentiation and tumorigenesis

scientific article

Molecular mechanisms of malignant conversion in skin carcinogenesis

Montagna Symposium 2011: 60th Anniversary--Advances in Science and Medicine Catalyzed by Pioneering Skin Research.

scientific article

Mouse cell clones for improved quantitation of carcinogen-induced altered differentiation

scientific article

Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network ⬇️

scientific article published on March 1, 1993

Mouse keratinocytes derived from initiated skin or papillomas are resistant to DNA strand breakage by benzoyl peroxide: a possible mechanism for tumor promotion mediated by benzoyl peroxide

scientific article published in December 1987

Mouse skin cells resistant to terminal differentiation associated with initiation of carcinogenesis.

scientific article published in September 1981

Mouse skin tumor progression results in differential expression of retinoic acid and retinoid X receptors.

scientific article published on July 1995

Multigenic control of skin tumor susceptibility in SENCARA/Pt mice.

scientific article published in June 1998

Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice

scientific article

Multistage carcinogenesis in the skin.

scientific article published in April 1996

MyD88 and its divergent toll in carcinogenesis.

scientific article published on 07 May 2013

Natural Synchrony Of Newborn Mouse Epidermal Cells In Vitro ⬇️

scientific article published on 01 May 1976

New strains of inbred SENCAR mice with increased susceptibility to induction of papillomas and squamous cell carcinomas in skin

scientific article published in September 1997

Nonmelanoma skin cancer, melanomas, warts, and viral oncogenesis.

scientific article published on November 1984

Novel S100A7 (psoriasin)/S100A15 (koebnerisin) subfamily: highly homologous but distinct in regulation and function

scientific article

Opposing activities of c-Fos and Fra-2 on AP-1 regulated transcriptional activity in mouse keratinocytes induced to differentiate by calcium and phorbol esters ⬇️

scientific article published on September 1, 1997

Opposing functions of psoriasin (S100A7) and koebnerisin (S100A15) in epithelial carcinogenesis.

scientific article published on 09 May 2013

Optimized conditions for the growth of human epidermal cells in culture

scientific article published on 01 August 1980

Organ culture of rodent prostate. Effects of polyamines and testosterone

scientific article published on 01 July 1976

Organ specificity and tumor promotion

scientific article published on 01 January 1983

Overexpression of retinoic acid receptors alpha and gamma into neoplastic epidermal cells causes retinoic acid-induced growth arrest and apoptosis.

scientific article

Overview of carcinogenesis: past, present and future

scientific article

Partial parallelism and partial blockade by bryostatin 1 of effects of phorbol ester tumor promoters on primary mouse epidermal cells

scientific article

Phorbol ester tumor promoters induce epidermal transglutaminase activity ⬇️

scientific article published on November 28, 1980

Phorbol esters stimulate DNA synthesis and ornithine decarboxylase activity in mouse epidermal cell cultures

scientific article published on July 29, 1976

Platinum-DNA adducts in leukocyte DNA correlate with disease response in ovarian cancer patients receiving platinum-based chemotherapy

scientific article

Polyclonal antibodies to quantitate cis-diamminedichloroplatinum(II)--DNA adducts in cancer patients and animal models

scientific article

Potassium mediation of calcium-induced terminal differentiation of epidermal cells in culture

scientific article published on 01 July 1983

Progress in cutaneous cancer research

scientific article

Properties of carcinogen altered mouse epidermal cells resistant to calcium-induced terminal differentiation ⬇️

scientific article published on November 1, 1983

Properties of murine pelage hair follicles in monolayer and collagen matrix cultures.

scientific article published in May 1991

Protein kinase C alpha-mediated chemotaxis of neutrophils requires NF-kappa B activity but is independent of TNF alpha signaling in mouse skin in vivo

scientific article published in February 2005

Protein kinase C negatively regulates Akt activity and modifies UVC-induced apoptosis in mouse keratinocytes

scientific article

Protein kinase C regulates keratinocyte transglutaminase (TGK) gene expression in cultured primary mouse epidermal keratinocytes induced to terminally differentiate by calcium

scientific article

Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector

scientific article

Protein kinase Cdelta-mediated phosphorylation of alpha6beta4 is associated with reduced integrin localization to the hemidesmosome and decreased keratinocyte attachment.

scientific article published in June 2001

Proteomic analysis of vascular endothelial growth factor-induced endothelial cell differentiation reveals a role for chloride intracellular channel 4 (CLIC4) in tubular morphogenesis

scientific article

Proto-oncogene expression during two-stage carcinogenesis in mouse skin

scientific article

Purification, crystallization and preliminary X-ray diffraction of human S100A15

scientific article

Purified epidermal pentapeptide inhibits proliferation and enhances terminal differentiation in cultured mouse epidermal cells

scientific article published in November 1986

Quantitation by electron microscopy of the binding of highly specific antibodies to benzo[a]pyrene-DNA adducts.

scientific article

Quantitation of benzo(a)pyrene-deoxyguanosine adducts by radioimmunoassay.

scientific article published in February 1980

Quantitation of cis-diamminedichloroplatinum II (cisplatin)-DNA-intrastrand adducts in testicular and ovarian cancer patients receiving cisplatin chemotherapy

scientific article

Quantitative assay for carcinogen altered differentiation in mouse epidermal cells

scientific article

Quantitative proteomic analysis of myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4

scientific article

RasGRP3 contributes to formation and maintenance of the prostate cancer phenotype

scientific article

RasGRP3, a Ras activator, contributes to signaling and the tumorigenic phenotype in human melanoma

scientific article published on 23 May 2011

Reciprocal modifications of CLIC4 in tumor epithelium and stroma mark malignant progression of multiple human cancers

scientific article published on January 2007

Reconstitution of hair follicle development in vivo: determination of follicle formation, hair growth, and hair quality by dermal cells

scientific article

Reduced DNA repair in cultured melanocytes and nevus cells from a patient with xeroderma pigmentosum

scientific article published in February 1989

Reduced migration, altered matrix and enhanced TGFbeta1 signaling are signatures of mouse keratinocytes lacking Sdc1

scientific article published on 31 July 2007

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

scientific article

Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins

scientific article published on January 1987

Regulated synthesis of low-molecular-weight antigens in keratinocyte cell cultures

scientific article published in October 1986

Regulation of epidermal transglutaminase activity and terminal differentiation by retinoids and phorbol esters ⬇️

scientific article published on December 1, 1983

Regulation of hair follicle development: an in vitro model for hair follicle invasion of dermis and associated connective tissue remodeling

scientific article published on July 1993

Regulation of intracellular free calcium in normal murine keratinocytes

scientific article

Relationship between the expression of differentiation-specific keratins 1 and 10 and cell proliferation in epidermal tumors

scientific article published on January 1992

Repair of daughter strand gaps in nascent DNA from mouse epidermal cells treated with dihydrodiol epoxide derivatives of benzo[a]pyrene ⬇️

scientific article published on November 22, 1979

Replication of DNA after binding of the carcinogen 7,12-dimethylbenz [a] anthracene

scientific article published on 01 December 1970

Response of carcinogen-altered mouse epidermal cells to phorbol ester tumor promoters and calcium

scientific article

Restoration of differentiation and suppression of tumorigenicity in somatic cell hybrids of human squamous carcinoma cells and keratinocytes.

scientific article published on December 1994

Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis

scientific article published on November 1989

Retinoic acid induces transglutaminase activity but inhibits cornification of cultured epidermal cells ⬇️

scientific article published on September 10, 1982

Retinoic acid-induced transglutaminase in mouse epidermal cells is distinct from epidermal transglutaminase

scientific article published on 01 February 1985

Retinoids inhibit promoter-dependent preneoplastic progression in mouse epidermal cell lines.

scientific article published in February 1981

Retinyl Acetate: Effect on Cellular Content of RNA in Epidermis in Cell Culture in Chemically Defined Medium ⬇️

scientific article published on November 16, 1973

Retinyl acetate modulation of cell growth kinetics and carcinogen--cellular interaction in mouse epidermal cell cultures.

scientific article published in March 1977

Role of Retinoic Acid Receptor-γ in DNA Damage-Induced Necroptosis

scientific article published on 18 June 2019

Role of differentiation in determining responses of epidermal cells to phorbol esters

scientific article published on 01 January 1982

Role of oncogenes and tumor suppressor genes in multistage carcinogenesis.

scientific article published in November 1994

Role of ornithine decarboxylase in epidermal tumorigenesis

scientific article

S-nitrosylation regulates nuclear translocation of chloride intracellular channel protein CLIC4.

scientific article

S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways

scientific article

SENCAR mouse skin tumors produced by promotion alone have A to G mutations in codon 61 of the c-rasHa gene ⬇️

scientific article published on September 1, 1994

Science Signaling Podcast for 21 June 2016: MET and skin cancer.

scientific article published on 21 June 2016

Screening compounds with a novel high-throughput ABCB1-mediated efflux assay identifies drugs with known therapeutic targets at risk for multidrug resistance interference

scientific article

Selective changes in laminin adhesion and alpha 6 beta 4 integrin regulation are associated with the initial steps in keratinocyte maturation.

scientific article

Selective detachment of a tetraploid subline of primary keratinocytes after treatment with the tumor promoter 12-0-tetradecanoylphorbol-13-acetate.

scientific article

Selenoproteins are essential for proper keratinocyte function and skin development

scientific article

Sensitivity of subpopulations of mouse skin papillomas to malignant conversion by urethane or 4-nitroquinoline N-oxide.

scientific article

Sensitivity to two-stage carcinogenesis of SENCAR mouse skin grafted to nude mice.

scientific article

Short-term retinoic acid treatment increases in vivo, but decreases in vitro, epidermal transglutaminase-K enzyme activity and immunoreactivity

scientific article published in September 1992

Signal transduction for proliferation and differentiation in keratinocytes

scientific article published on January 1988

Skin calcium-binding protein is a parvalbumin of the panniculus carnosus

scientific article published in February 1986

Skin tumorigenesis and Ki-ras and Ha-ras mutations in tumors from adult mice exposed in utero to 3'-azido-2',3'-dideoxythymidine

scientific article published on September 1998

Specific epidermal protein markers are modulated during calcium-induced terminal differentiation ⬇️

scientific article published on June 1, 1983

Specific protein kinase C isozymes mediate the induction of keratinocyte differentiation markers by calcium.

scientific article published in February 1995

Specific quantification of mouse and human keratin proteins by radioimmunoassay

scientific article published on April 1980

Spontaneous Ha-ras gene activation in cultured primary murine keratinocytes: consequences of Ha-ras gene activation in malignant conversion and malignant progression

scientific article published on January 1989

Spontaneous skin erosions and reduced skin and corneal wound healing characterize CLIC4(NULL) mice

scientific article

Src family kinases phosphorylate protein kinase C delta on tyrosine residues and modify the neoplastic phenotype of skin keratinocytes

scientific article

Staurosporine induces a complete program of terminal differentiation in neoplastic mouse keratinocytes via activation of protein kinase C.

scientific article

Staurosporine induces a sequential program of mouse keratinocyte terminal differentiation through activation of PKC isozymes

scientific article

Staurosporine induces protein kinase C agonist effects and maturation of normal and neoplastic mouse keratinocytes in vitro ⬇️

scientific article published on September 1, 1991

Stimulated DNA synthesis in mouse epidermal cell cultures treated with 12-O-tetradecanoyl-phorbol-13-acetate ⬇️

scientific article published on 01 November 1976

Strain-dependent differences in malignant conversion of mouse skin tumors is an inherent property of the epidermal keratinocyte

scientific article published on 22 April 2004

Strontium induces murine keratinocyte differentiation in vitro in the presence of serum and calcium ⬇️

scientific article published on 01 March 1993

Subunit structure of the mouse epidermal keratin filament ⬇️

scientific article published on March 27, 1979

Susceptibility determinants for mouse epidermal carcinogenesis.

scientific article

Suspension-induced murine keratinocyte differentiation is mediated by calcium

scientific article published on 01 February 1996

Synthesis of hyaluronic acid is decreased and synthesis of proteoglycans is increased when cultured mouse epidermal cells differentiate

scientific article published on 01 June 1986

Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies ⬇️

scientific article published on July 10, 1984

T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis

scientific article published on 04 June 2019

TGF alpha stimulates growth of skin papillomas by autocrine and paracrine mechanisms but does not cause neoplastic progression

scientific article published in January 1988

TGF-beta signalling is regulated by Schnurri-2-dependent nuclear translocation of CLIC4 and consequent stabilization of phospho-Smad2 and 3

scientific article

Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma

scientific article published on 01 October 1994

Targeted disruption of glutathione peroxidase 4 in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2.

scientific article published on 30 January 2013

Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras ⬇️

scientific article published on August 1, 1997

Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation ⬇️

scientific article published on July 1, 1993

The Binding of Benz [a] anthracene to Replicating and NonReplicating DNA in Cell Culture

scientific article published on December 1, 1970

The binding of 7,12-dimethylbenz(a)anthracene to replicating and non-replicating DNA in cell culture ⬇️

scientific article published on 01 December 1969

The black box illuminated: signals and signaling

scientific article

The contribution of epidermal stem cells to skin cancer

scientific article published on January 2005

The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors.

scientific article published in July 2000

The erbstatin analogue methyl 2,5-dihydroxycinnamate cross-links proteins and is cytotoxic to normal and neoplastic epithelial cells by a mechanism independent of tyrosine kinase inhibition ⬇️

scientific article published on November 1, 1995

The growth of fetal mouse skin in cell culture and transplantation to F1 mice

scientific article

The high-risk benign tumor: evidence from the two-stage skin cancer model and relevance for human cancer

scientific article published on August 2007

The homeoprotein DLX3 and tumor suppressor p53 co-regulate cell cycle progression and squamous tumor growth

scientific article published on 2 November 2015

The human promyelocytic leukemia protein is a tumor suppressor for murine skin carcinogenesis

scientific article published on July 2009

The in vitro analysis of biochemical changes relevant to skin carcinogenesis

scientific article

The induction of epidermal transglutaminase and terminal differentiation by tumor promoters in cultured epidermal cells ⬇️

scientific article published on November 1, 1983

The malignant conversion step of mouse skin carcinogenesis

scientific article

The measurement of cisplatin-DNA adduct levels in testicular cancer patients

scientific article

The mouse S100A15 ortholog parallels genomic organization, structure, gene expression, and protein-processing pattern of the human S100A7/A15 subfamily during epidermal maturation

scientific article

The organellular chloride channel protein CLIC4/mtCLIC translocates to the nucleus in response to cellular stress and accelerates apoptosis

scientific article published on 10 November 2003

The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis

scientific article published in May 1998

The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis--thirty-third G. H. A. Clowes Memorial Award Lecture.

scientific article published on March 1994

The role of growth factors in mouse skin tumor promotion and premalignant progression

scientific article published on January 1995

The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature

scientific article

The study of tumor promotion in a cell culture model for mouse skin--a tissue that exhibits multistage carcinogenesis in vivo

scientific article published on 01 January 1982

The suprabasal expression of alpha 6 beta 4 integrin is associated with a high risk for malignant progression in mouse skin carcinogenesis.

scientific article

The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription

scientific article published on 06 May 2019

The tumor promoter 12-O-tetradecanoylphorbol-13-acetate induces ornithine decarboxylase in proliferating basal cells but not in differentiating cells from mouse epidermis

scientific article published on May 1981

The tumor promoter, 12-O-tetradecanoylphorbol-13-acetate accelerates keratinocyte differentiation and stimulates growth of an unidentified cell type in cultured human epidermis ⬇️

scientific article published on 01 January 1982

The use of cDNA clones and monospecific antibodies as probes to monitor keratin gene expression

scientific article published on 01 January 1985

The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes ⬇️

scientific article published on January 1, 1990

Thirteenth Aspen Cancer Conference: workshop on mechanisms of toxicity and carcinogenesis

scientific article published on 01 June 1999

Tissue homeostasis and the control of the neoplastic phenotype in epithelial cancers

scientific article

Topical Application of a Dual ABC Transporter Substrate and NF-κB Inhibitor Blocks Multiple Sources of Cutaneous Inflammation in Mouse Skin

scientific article published on 23 January 2019

Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion.

scientific article published on April 1998

Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis

scientific article published on June 1988

Transcripts encoding protein kinase C-alpha, -delta, -epsilon, -zeta, and -eta are expressed in basal and differentiating mouse keratinocytes in vitro and exhibit quantitative changes in neoplastic cells

scientific article published on January 1992

Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression

scientific article published on September 1986

Transformation of epidermal cells in culture.

scientific article

Transforming growth factor beta 1 suppresses genomic instability independent of a G1 arrest, p53, and Rb

scientific article published on 01 August 1996

Transforming growth factor beta1 enhances tumor promotion in mouse skin carcinogenesis

scientific article

Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys

scientific article published in November 1997

Tumor promoters induce the synthesis of a secreted glycoprotein in mouse skin and cultured primary mouse epidermal cells ⬇️

scientific article published on January 1, 1981

Tumorigenic suppression of a human cutaneous squamous cell carcinoma cell line in the nude mouse skin graft assay.

scientific article published on December 1992

Tumour promoter induces anchorage independence irreversibly ⬇️

scientific article published on October 18, 1979

Two oncogenes, v-fos and v-ras, cooperate to convert normal keratinocytes to squamous cell carcinoma

scientific article published on January 1990

Two-stage tumor promotion in mouse skin: an alternative interpretation

scientific article published on 01 April 1985

Ultrasensitive enzymatic radioimmunoassay (USERIA) detects femtomoles of acetylaminofluorene-DNA adducts.

scientific article published in May 1980

Ultraviolet Light Irradiation Increases Cellular Diacylglycerol and Induces Translocation of Diacylglycerol Kinase in Murine Keratinocytes ⬇️

scientific article published on August 1, 1992

Xeroderma pigmentosum and D. N. A. repair

scientific article published in March 1971

[1] Isolation and utilization of epidermal keratinocytes for oncogene research

scientific article published on 01 January 1995

c-fos is required for malignant progression of skin tumors.

scientific article

cis-Diamminedichloroplatinum (II)-DNA adduct formation in renal, gonadal, and tumor tissues of male and female rats.

scientific article published in February 1987

mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53

scientific article

p53 and tumor necrosis factor alpha regulate the expression of a mitochondrial chloride channel protein

scientific journal article

p53 gene dosage modifies growth and malignant progression of keratinocytes expressing the v-rasHa oncogene.

scientific article published in November 1994

p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein

scientific article published on June 1995

v-Ha-ras-induced mouse skin papillomas exhibit aberrant expression of keratin K13 as do their 7,12-dimethylbenz[a]anthracene/12-O-tetradecanoylphorbol-13-acetate -induced analogues

scientific article published on January 1991

‘Going green’ against skin cancer ⬇️

scientific article published on December 1, 2010

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