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List of works by Joel Gelernter

5-HTTLPR as a potential moderator of the effects of adverse childhood experiences on risk of antisocial personality disorder

scientific article

A CHRNA5 Smoking Risk Variant Decreases the Aversive Effects of Nicotine in Humans

scientific article published on 7 May 2015

A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African-American women

scientific article published on 13 October 2011

A Preliminary Examination of the Relationship Between the 5-HTTLPR and Childhood Emotional Abuse on Depressive Symptoms in 10-12-Year-Old Youth

scientific article

A chromosome 14 risk locus for simple phobia: results from a genomewide linkage scan

scientific article published in January 2003

A common genetic variant in the neurexin superfamily member CNTNAP2 is associated with increased risk for selective mutism and social anxiety-related traits

scientific article

A complex interplay between personality domains, marital status and a variant in CHRNA5 on the risks of cocaine, nicotine dependences and cocaine-induced paranoia

scientific article

A detailed physical map of the 6p reading disability locus, including new markers and confirmation of recombination suppression

scientific article published on 13 August 2002

A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients

scientific article

A genome-wide gene-by-trauma interaction study of alcohol misuse in two independent cohorts identifies PRKG1 as a risk locus

scientific article published on 07 March 2017

A genomewide linkage scan of cocaine dependence and major depressive episode in two populations

scientific article

A large-scale genome-wide association study meta-analysis of cannabis use disorder

scientific article published on 20 October 2020

A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia

scientific article

A polymorphism of the beta1-adrenergic receptor is associated with low extraversion

scientific article

A prospective cohort study investigating factors associated with depression during medical internship

scientific article

A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke.

scientific article published on 12 April 2016

A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder

scientific article published on 27 November 2017

A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus

scientific article

A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans

scientific article published on 18 November 2019

A sequencing-based survey of functional APAF1 alleles in a large sample of individuals with affective illness and population controls

scientific article published on January 2010

ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure

scientific article

ADH1A variation predisposes to personality traits and substance dependence

scientific article

ADH1B: From alcoholism, natural selection, and cancer to the human phenome

scientific article published on 27 March 2017

ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies

scientific article

ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case-control association studies

scientific article

ADH7 variation modulates extraversion and conscientiousness in substance-dependent subjects

scientific article

ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample

scientific journal article

Addictions biology: haplotype-based analysis for 130 candidate genes on a single array

scientific article published on 12 May 2008

Adolescent cannabis use increases risk for cocaine-induced paranoia

scientific article

Adverse childhood events as risk factors for substance dependence: partial mediation by mood and anxiety disorders

scientific article published on 08 August 2009

Agitated depression in substance dependence

scientific article

Alcohol Misuse and Co-Occurring Mental Disorders Among New Soldiers in the U.S. Army

scientific article published on 24 November 2016

Alcohol and nicotine codependence-associated DNA methylation changes in promoter regions of addiction-related genes

scientific article published on 06 February 2017

Alcohol-metabolizing genes and alcohol phenotypes in an Israeli household sample

scientific article published on 29 July 2013

Alcohol-responsive genes identified in human iPSC-derived neural cultures

article

Alleles of a functional serotonin transporter promoter polymorphism are associated with major depression in alcoholics

scientific article published in September 2003

Allelic Variation in the D4 Dopamine Receptor (DRD4) Gene Does Not Predict Response to Clozapine

article

Allelic variation of calsyntenin 2 (CLSTN2) modulates the impact of developmental tobacco smoke exposure on mnemonic processing in adolescents

scientific article

Analysis of variations in the tryptophan hydroxylase-2 (TPH2) gene in cocaine dependence

scientific article

Ancestry informative markers for distinguishing between Thai populations based on genome-wide association datasets

scientific article

Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors

scientific article published on 9 October 2017

Apolipoprotein E epsilon4 allele increases risk for psychotic symptoms in Alzheimer's disease

scientific article

Apolipoprotein E epsilon4 allele is unrelated to cognitive or functional decline in Alzheimer's disease: retrospective and prospective analysis

scientific article published on 12 May 2006

Apolipoprotein E epsilon4 is associated with atrophy of the amygdala in Alzheimer's disease

article

Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study

scientific article published on 06 August 2019

Apolipoprotein E gene polymorphism, trauma burden, and posttraumatic stress symptoms in U.S. military veterans: Results from the National Health and Resilience in Veterans Study.

scientific article published on 24 November 2017

Arguable assumptions, debatable conclusions

scientific article published on 14 December 2009

Array-based profiling of DNA methylation changes associated with alcohol dependence

scientific article

Assignment of the 5HT7 receptor gene (HTR7) to chromosome 10q and exclusion of genetic linkage with tourette syndrome

article

Assignment of the norepinephrine transporter protein (NET1) locusto chromosome 16

article

Association Study of Alcoholism Subtypes with a Functional Promoter Polymorphism in the Serotonin Transporter Protein Gene

article

Association between COMT, PTSD, and increased smoking following hurricane exposure in an epidemiologic sample

scientific article

Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population

scientific article published in April 2005

Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations

scientific article published on 08 June 2011

Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence

scientific article

Association of CHRNA4 polymorphisms with smoking behavior in two populations

scientific article published on 28 March 2011

Association of COL25A1 with comorbid antisocial personality disorder and substance dependence

scientific article published on 31 January 2012

Association of CRHR1 variants and posttraumatic stress symptoms in hurricane exposed adults

scientific article

Association of gamma-aminobutyric acid A receptor α2 gene (GABRA2) with alcohol use disorder

scientific article

Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case–control and family samples

Association of markers in the 3' region of the GluR5 kainate receptor subunit gene to alcohol dependence

scientific article published on May 2009

Association of psychiatric and substance use disorder comorbidity with cocaine dependence severity and treatment utilization in cocaine-dependent individuals

scientific article published on 04 September 2008

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

scientific article

Association of variants in MANEA with cocaine-related behaviors

scientific article published on March 2009

Association study of DTNBP1 with schizophrenia in a US sample

scientific article

Association study of cannabinoid receptor gene (CNR1) alleles and drug dependence

article

Association study of personality factors and the Asn40Asp polymorphism at the mu-opioid receptor gene (OPRM1).

scientific article

Association study of the CNR1 gene exon 3 alternative promoter region polymorphisms and substance dependence

scientific article published on July 2006

Attachment style moderates effects of FKBP5 polymorphisms and childhood abuse on post-traumatic stress symptoms: Results from the National Health and Resilience in Veterans Study

scientific article published on 11 September 2017

Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability

scientific article published on 01 July 2019

Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

scientific article published on 17 May 2019

Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

scientific article published on 03 September 2019

Author Correction: Genomewide Study of Epigenetic Biomarkers of Opioid Dependence in European- American Women

scientific article published on 05 December 2019

Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances

scientific article published on 21 February 2012

BDNF variants, premorbid educational attainment, and disease characteristics in Alzheimer's disease: an exploratory study

scientific article

Biases and errors on allele frequency estimation and disease association tests of next-generation sequencing of pooled samples

scientific article

Bipolar affective disorder is not linked to norepinephrine transporter protein or serotonin transporter protein genes

article

Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence

scientific article published on June 2006

Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children

scientific article published on 3 February 2006

C957T polymorphism of the dopamine D2 receptor gene modulates the effect of nicotine on working memory performance and cortical processing efficiency

scientific article published on 9 August 2006

CHRM2 gene predisposes to alcohol dependence, drug dependence and affective disorders: results from an extended case-control structured association study

scientific article published on 6 July 2005

CHRM2 variation predisposes to personality traits of agreeableness and conscientiousness

CHRNA4 and ANKK1 Polymorphisms Influence Smoking-Induced Nicotinic Acetylcholine Receptor Upregulation

scientific article published on 31 March 2016

CHRNA5/A3/B4 Variant rs3743078 and Nicotine-Related Phenotypes: Indirect Effects Through Nicotine Craving

scientific article published on March 2016

CNR1 variation modulates risk for drug and alcohol dependence

scientific article

COMT Val158Met modulates subjective responses to intravenous nicotine and cognitive performance in abstinent smokers

scientific article published on 5 March 2013

COMT polymorphisms and anxiety-related personality traits

scientific article

Candidate Genes and Psychiatric Genetics: Tomorrow Never Knows

article

Candidate gene study of the catecholamine system in schizophrenia

article

Case control and family-based studies of tryptophan hydroxylase gene A218C polymorphism and suicidality in adolescents.

scientific article published in July 2001

Central serotonin transporter availability measured with [123I]beta-CIT SPECT in relation to serotonin transporter genotype

scientific article

Characterization of a likelihood based method and effects of markers informativeness in evaluation of admixture and population group assignment

scientific article

Child abuse and epigenetic mechanisms of disease risk

scientific article published on February 2013

Child abuse, depression, and methylation in genes involved with stress, neural plasticity, and brain circuitry

scientific article

Childhood adversity increases risk for nicotine dependence and interacts with α5 nicotinic acetylcholine receptor genotype specifically in males

scientific article published on 19 October 2011

Childhood adversity moderates the effect of ADH1B on risk for alcohol-related phenotypes in Jewish Israeli drinkers

scientific article published on 24 October 2013

Clinical features of methamphetamine-induced paranoia and preliminary genetic association with DBH-1021C→T in a Thai treatment cohort

scientific article

Cognitive flexibility is associated with KIBRA variant and modulated by recent tobacco use.

scientific article

Comorbid psychiatric diagnoses and their association with cocaine-induced psychosis in cocaine-dependent subjects

scientific article published in September 2007

Comparing the utility of homogeneous subtypes of cocaine use and related behaviors with DSM-IV cocaine dependence as traits for genetic association analysis

scientific article

Components of cross-frequency modulation in health and disease

scientific article

Confirmation and fine mapping of the chromosome 1 alcohol dependence risk locus.

scientific article published in March 2004

Confirmation and generalization of an alcohol-dependence locus on chromosome 10q.

scientific article

Correlates of co-occurring ADHD in drug-dependent subjects: prevalence and features of substance dependence and psychiatric disorders

scientific article published on 13 May 2008

Cortical β-amyloid burden, gray matter, and memory in adults at varying APOE ε4 risk for Alzheimer's disease

scientific article

Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations.

scientific article

Cross-Phenotype Polygenic Risk Score Analysis of Persistent Post-Concussive Symptoms in U.S. Army Soldiers with Deployment-Acquired Traumatic Brain Injury

scientific article published on 20 July 2016

D2 Dopamine Receptor Gene (DRD2) Allele and Haplotype Frequencies in Alcohol Dependent and Control Subjects No Association with Phenotype or Severity of Phenotype

article

D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects

scientific article

DCDC2 is associated with reading disability and modulates neuronal development in the brain

scientific article

DNA co-methylation modules in postmortem prefrontal cortex tissues of European Australians with alcohol use disorders

scientific article

DOPA decarboxylase gene is associated with nicotine dependence

article

DRD2 allele frequencies and linkage disequilibria, including the -141CIns/Del promoter polymorphism, in European-American, African-American, and Japanese subjects

scientific article published in July 1998

DSM-5 gambling disorder: prevalence and characteristics in a substance use disorder sample

scientific article

Deciphering the Biological Mechanisms Underlying the Genome-Wide Associations between Computerized Device Use and Psychiatric Disorders

scientific article published on 21 November 2019

Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence

scientific article

Demographic changes and marker properties affect detection of human population differentiation

scientific article

Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10.

scientific article published on 18 October 2008

Developmental Perspective on the Role of Genes in Smoking Risk ⬇️

scientific article published on April 1, 2011

Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA).

scientific article published in December 2005

Differentially co-expressed genes in postmortem prefrontal cortex of individuals with alcohol use disorders: influence on alcohol metabolism-related pathways

scientific article

Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence

scientific article

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

scholarly article published 3 June 2017

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

scientific article published on 26 November 2018

Dissecting ancestry genomic background in substance dependence genome-wide association studies

scientific article

Dissecting the genetic association of C-reactive protein with PTSD, traumatic events, and social support

scientific article published on 16 March 2020

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

scientific article

Dopamine D2 Receptor and Tourette's Syndrome-Reply

scholarly article by Joel Gelernter et al published 1 May 1995 in Archives of Neurology

Dopamine beta-hydroxylase gene (DbetaH) -1021C-->T influences self-reported paranoia during cocaine self-administration

scientific article

Dopamine β-hydroxylase: two polymorphisms in linkage disequilibrium at the structural gene DBH associate with biochemical phenotypic variation

article

Drinking and smoking polygenic risk is associated with childhood and early-adulthood psychiatric and behavioral traits independently of substance use and psychiatric genetic risk

scientific article published on 13 November 2021

Early-life stress, corpus callosum development, hippocampal volumetrics, and anxious behavior in male nonhuman primates

scientific article

Early-life stress, corticotropin-releasing factor, and serotonin transporter gene: a pilot study

scientific article

Effects of ANK3 variation on gray and white matter in bipolar disorder

scientific article published on 31 May 2016

Effects of opioid receptor gene variation on targeted nalmefene treatment in heavy drinkers

scientific article

Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder

scientific article

Empirically derived subtypes of opioid use and related behaviors

scientific article

Epigenome-Wide DNA Methylation Association Analysis Identified Novel Loci in Peripheral Cells for Alcohol Consumption Among European American Male Veterans

scientific article published on 30 August 2019

Epigenome-wide association study of posttraumatic stress disorder identifies novel loci in U.S. military veterans

scientific article published on 17 February 2022

Erratum: Genetic risk prediction and neurobiological understanding of alcoholism

scholarly article published in Translational Psychiatry

Ethanol upregulates NMDA receptor subunit gene expression in human embryonic stem cell-derived cortical neurons

scientific article published on 12 August 2015

Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes.

scientific article

Evidence of CNIH3 involvement in opioid dependence.

scientific article published on 4 August 2015

Evidence of Polygenic Adaptation in the Systems Genetics of Anthropometric Traits

scientific article

Examining the relation between the serotonin transporter 5-HTTPLR genotype x trauma exposure interaction on a contemporary phenotypic model of posttraumatic stress symptomatology: a pilot study

scientific article published on 24 November 2012

Exome sequencing and genome-wide copy number variant mapping reveal novel associations with sensorineural hereditary hearing loss

scientific article

Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits

scientific article published on 03 November 2020

Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants

scientific article published on 03 December 2013

Eye color: A potential indicator of alcohol dependence risk in European Americans

scientific article published on 29 April 2015

FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study.

scientific article published on 5 April 2016

FKBP5 variation is associated with the acute and chronic effects of nicotine

scientific article

Family-based association study of serotonin transporter promoter in suicidal adolescents: no association with suicidality but possible role in violence traits.

scientific article

Functional impact of a single-nucleotide polymorphism in the OPRD1 promoter region

scientific article

Further analyses support the association between light eye color and alcohol dependence

Further clarification of the contribution of the ADH1C gene to vulnerability of alcoholism and selected liver diseases

scientific article published on 5 April 2012

GABRA2 and KIBRA genotypes predict early relapse to substance use.

scientific article published on 29 November 2011

GABRA2 genotype, impulsivity, and body mass

scientific article published on September 2012

GABRG1 and GABRA2 variation associated with alcohol dependence in African Americans

scientific article published on 15 September 2011

GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation

scientific article

GRIK1 genotype and daily expectations of alcohol's positive effects moderate the reduction of heavy drinking by topiramate

scientific article

GRIK1 genotype moderates topiramate's effects on daily drinking level, expectations of alcohol's positive effects and desire to drink

scientific article

GWAS and network analysis of co-occurring nicotine and alcohol dependence identifies significantly associated alleles and network

scientific article published on 28 November 2018

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia

scientific article published on 27 August 2018

Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment

scientific article published on September 2006

Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders

scientific article

Genetic Association between Dopamine Transporter Protein Alleles and Cocaine-Induced Paranoia

scholarly article by Joel Gelernter et al published April 1995 in Neuropsychopharmacology

Genetic Association between Dopamine Transporter Protein Alleles and Cocaine-Induced Paranoia

scholarly article by Joel Gelernter published April 1995 in Neuropsychopharmacology

Genetic Basis of Social Anxiety Disorder

article published in 2010

Genetic Relationship between Schizophrenia and Nicotine Dependence

scientific article published on 10 May 2016

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

scientific article published on 25 October 2017

Genetic and environmental predictors of early alcohol use.

scientific article published on 21 November 2006

Genetic and psychosocial predictors of alcohol use trajectories among disaster-exposed adolescents.

scientific article published on 8 June 2017

Genetic association between dopamine transporter protein alleles and cocaine-induced paranoia

scientific article published on November 1994

Genetic association of impulsivity in young adults: a multivariate study

scientific article

Genetic associations of brain structural networks in schizophrenia: a preliminary study

scientific article

Genetic associations with performance on a behavioral measure of distress intolerance

scientific article published on 22 October 2011

Genetic associations with suicide attempt severity and genetic overlap with major depression

scientific article published on 17 January 2019

Genetic factor common to schizophrenia and HIV infection is associated with risky sexual behavior: antagonistic vs. synergistic pleiotropic SNPs enriched for distinctly different biological functions

scientific article

Genetic influences of cortical gray matter in language-related regions in healthy controls and schizophrenia.

scientific article

Genetic influences of resting state fMRI activity in language-related brain regions in healthy controls and schizophrenia patients: a pilot study

scientific article published on March 2013

Genetic risk prediction and neurobiological understanding of alcoholism

scientific article

Genetic risk variants for social anxiety

scientific article

Genetic risk variants for social anxiety

Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth.

scientific article

Genetic variation in 5HTTLPR is associated with emotional resilience

scientific article

Genetic-epigenetic interactions in cis: a major focus in the post-GWAS era

scientific article

Genetically determined schizophrenia is not associated with impaired glucose homeostasis

scientific article published on 29 October 2017

Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits

scientific article published in 2022

Genetics of Substance Dependence

article

Genetics of alcohol dependence

article

Genetics of complex traits in psychiatry

scientific article

Genome scan for loci predisposing to anxiety disorders using a novel multivariate approach: strong evidence for a chromosome 4 risk locus

scientific article

Genome-Wide Association Study of Alcohol Dependence Implicates KIAA0040 on Chromosome 1q.

scientific article published on 13 December 2011

Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes

scientific article published on 11 July 2019

Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers

scientific article published on 11 May 2016

Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.

scientific article published on 11 January 2018

Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks

scientific article published on 30 March 2016

Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci

scientific article published on 08 April 2019

Genome-wide analysis of insomnia disorder

scientific article published on 8 March 2018

Genome-wide association meta-analysis of age at first cannabis use

scientific article published on 19 August 2018

Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence

scientific article published on 3 October 2017

Genome-wide association study identifies glutamate ionotropic receptor GRIA4 as a risk gene for comorbid nicotine dependence and major depression

article

Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder

scientific journal article

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci

scientific article published in 2022

Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

scientific article published on 02 April 2019

Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q

scientific journal article

Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison

scientific article published on 07 October 2019

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci

scientific article

Genome-wide association study of body mass index in subjects with alcohol dependence

scientific article published on 12 October 2015

Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene

scientific article published on 20 August 2013

Genome-wide association study of cognitive flexibility assessed by the Wisconsin Card Sorting Test

scientific article published on 01 July 2018

Genome-wide association study of copy number variations (CNVs) with opioid dependence

scientific article

Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium

scientific article

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans.

scientific article

Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways

scientific article published on 19 October 2013

Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans

scientific article published on 29 July 2019

Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals

scientific article published on 20 October 2020

Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1.

scientific article published on 24 January 2017

Genome-wide linkage scan for loci predisposing to social phobia: evidence for a chromosome 16 risk locus

scientific article

Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits

scientific article published on 25 May 2020

Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence

scientific article published on 06 October 2015

Genome-wide scan identifies opioid overdose risk locus close to MCOLN1

scientific article published on 30 July 2019

Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans

scientific article

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

scientific article published on 22 February 2017

Genomewide Gene-by-Sex Interaction Scans Identify ADGRV1 for Sex Differences in Opioid Dependent African Americans

scientific article published on 02 December 2019

Genomewide Linkage Scan for Nicotine Dependence: Identification of a Chromosome 5 Risk Locus

Genomewide Study of Epigenetic Biomarkers of Opioid Dependence in European- American Women

scientific article published on 15 March 2019

Genomewide association studies of suicide attempts in US soldiers

scientific article published on 13 September 2017

Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia

scientific article published in July 2005

Genomewide linkage scan for opioid dependence and related traits

scientific article

Genomic influences on self-reported childhood maltreatment

scientific article published on 27 January 2020

Genomic regions controlling corticosterone levels in rats

scientific article published in March 2004

Genotype-controlled analysis of plasma dopamine beta-hydroxylase activity in psychotic unipolar major depression

scientific article (publication date: March 2002)

Gilles de la Tourette Syndrome Is Not Linked to D2-Dopamine Receptor

scientific article published on 01 November 1990

Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations

scientific article published on 3 November 2006

Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence

scientific article

Heritability and Genetics of Anxiety Disorders

article

Human clock, PER1 and PER2 polymorphisms: lack of association with cocaine dependence susceptibility and cocaine-induced paranoia

scientific article published in December 2006

Hypermethylation of OPRM1 promoter region in European Americans with alcohol dependence

scientific article

Identification of POMC exonic variants associated with substance dependence and body mass index

scientific article

Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes

scientific article

Identification of population substructure among Jews using STR markers and dependence on reference populations included

scientific article

Improved methods to identify stable, highly heritable subtypes of opioid use and related behaviors

scientific article

Improving genetic risk prediction by leveraging pleiotropy

scientific article published on 13 December 2013

In Reply

Incentive program decreases no-shows in nontreatment substance abuse research

scientific article published in November 2005

Increased Risk of Multiple Outpatient Surgeries in African-American Carriers of Transthyretin Val122Ile Mutation Is Modulated by Non-Coding Variants

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

scientific article

Indoor tanning and tanning dependence in young people after a diagnosis of basal cell carcinoma

scientific article published on September 2013

Influence of RGS2 on anxiety-related temperament, personality, and brain function

scientific article published in March 2008

Influence of vascular endothelial growth factor variation on human hippocampus morphology

scientific article published on 15 August 2008

Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence

scientific article

Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits

scientific article published in 2022

Integration of evidence across human and model organism studies: A meeting report

scientific article published on 24 April 2021

Inter-observer reliability of DSM-5 substance use disorders

scientific article published on 27 May 2015

Inter-rater reliability and concurrent validity of DSM-IV opioid dependence in a Hmong isolate using the Thai version of the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA).

scientific article

Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample

scientific article

Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder

scientific article

Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity

scientific article

Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations

scientific article

Interleukin 1B gene (IL1B) variation and internalizing symptoms in maltreated preschoolers

scientific article published on November 2014

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

scientific article published on 08 October 2019

Interpopulation linkage disequilibrium patterns of GABRA2 and GABRG1 genes at the GABA cluster locus on human chromosome 4

scientific article

Intravenous physostigmine increases cerebrospinal fluid neuropeptide-Y

scientific article published on 01 October 1989

Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans

scientific article

Inviting in the Exome for Alcohol and Smoking Traits

scientific article published on 01 June 2019

It is time to take a stand for medical research and against terrorism targeting medical scientists

scientific article

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

article published in 2018

Letter to the Editor

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

scientific article published on 26 February 2020

Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans

scientific article published on 19 April 2012

Linkage genome scan for loci predisposing to panic disorder or agoraphobia

Linkage map of eight human chromosome 11q markers, including DRD2, spanning 60 cM

scientific article published on January 1, 1992

Linkage mapping of serotonin transporter protein gene SLC6A4 on chromosome 17

article

M(3): an improved SNP calling algorithm for Illumina BeadArray data

scientific article

MAOA genotype, maltreatment, and aggressive behavior: the changing impact of genotype at varying levels of trauma

scientific article

Markers in the 5'-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene

scientific article

Measurement of admixture proportions and description of admixture structure in different U.S. populations

scientific article

Medical informatics is a research field

scientific article published on 01 July 1984

Meta-Analyses of Genome-Wide Association Data Hold New Promise for Addiction Genetics

scientific article

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

scientific article

Meta-analysis of 15 genome-wide linkage scans of smoking behavior

scientific article

Methylation in OTX2 and related genes, maltreatment, and depression in children

scientific article published on 21 July 2018

Modification of the association between serotonin transporter genotype and risk of posttraumatic stress disorder in adults by county-level social environment

scientific article published on 19 February 2009

Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans

scientific article

Multiple OPR genes influence personality traits in substance dependent and healthy subjects in two American populations

scientific article

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

scientific article

Multivariate Imaging Genetics Study of MRI Gray Matter Volume and SNPs Reveals Biological Pathways Correlated with Brain Structural Differences in Attention Deficit Hyperactivity Disorder

scientific article published on 25 July 2016

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

scientific article published on 26 August 2021

Mutation screen of theGAD2 gene and association study of alcoholism in three populations

article

NOTCH4 gene haplotype is associated with schizophrenia in African Americans

scientific article

NPY moderates the relation between hurricane exposure and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults

scientific article

Neuropeptide Y-like immunoreactivity in schizophrenia. Relationships with clinical measures

scientific article published on October 1990

Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humans

scientific article published on 19 August 2014

No allelic association of an exon 13 polymorphism of the Gs? gene to alcohol and/or drug dependence

article

No association between ADCYAP1R1 and post-traumatic stress disorder in two independent samples

scientific article

No association between D2 dopamine receptor (DRD2) alleles or haplotypes and cocaine dependence or severity of cocaine dependence in European- and African-Americans

scientific article published in February 1999

No association between D2 dopamine receptor (DRD2) “A” system alleles, or DRD2 haplotypes, and posttraumatic stress disorder

scientific article published on 01 March 1999

No association between D3 dopamine receptor (DRD3) alleles and cocaine dependence

scholarly article by MARTIN FREIMER et al published June 1996 in Addiction Biology

No association between an allele at the D2 dopamine receptor gene (DRD2) and alcoholism

scientific article published in October 1991

No structural mutation in the dopamine D2 receptor gene in alcoholism or schizophrenia. Analysis using denaturing gradient gel electrophoresis

scientific article published in January 1994

Novel QTL at chromosome 6p22 for alcohol consumption: Implications for the genetic liability of alcohol use disorders

scientific article

Novel gene identified in an exome-wide association study of tanning dependence

scientific article

Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: results from the VA Cooperative Study

scientific article

Ordered subset linkage analysis based on admixture proportion identifies new linkage evidence for alcohol dependence in African-Americans

scientific article published on 13 December 2012

Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study

scientific article published on 08 July 2017

Personality traits of agreeableness and extraversion are associated with ADH4 variation

scientific article

Pervasive pleiotropy between psychiatric disorders and immune disorders revealed by integrative analysis of multiple GWAS.

scientific article

Pharmacogenetics of naltrexone and disulfiram in alcohol dependent, dually diagnosed veterans

scientific article

Phenome-Wide Association Study for Alcohol and Nicotine Risk Alleles in 26394 Women

scientific article published on 17 May 2016

Phenome-wide association study for CYP2A6 alleles: rs113288603 is associated with hearing loss symptoms in elderly smokers

scientific article

Phenomic Impact of Genetically-Determined Euthyroid Function and Molecular Differences between Thyroid Disorders

scientific article published on 21 September 2018

Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort

scientific article

Polygenic risk for autism spectrum disorder associates with anger recognition in a neurodevelopment-focused phenome-wide scan of unaffected youths from a population-based cohort

scientific article published on 17 September 2020

Polymorphism of DCDC2 Reveals Differences in Cortical Morphology of Healthy Individuals-A Preliminary Voxel Based Morphometry Study

scientific article published on March 2008

Polymorphism of the 5-HT1B receptor gene (HTR1B): strong within-locus linkage disequilibrium without association to antisocial substance dependence

scientific article published in January 2002

Population admixture modulates risk for alcohol dependence

scientific article published on 22 March 2009

Population studies of polymorphisms at loci of neuropsychiatric interest (tryptophan hydroxylase (TPH), dopamine transporter protein (SLC6A3), D3 dopamine receptor (DRD3), apolipoprotein E (APOE), mu opioid receptor (OPRM1), and ciliary neurotrophic

scientific article published in September 1998

Population-specific effects of the Asn40Asp polymorphism at the mu-opioid receptor gene (OPRM1) on HPA-axis activation

scientific article

Posttreatment effects of topiramate treatment for heavy drinking.

scientific article

Practical population group assignment with selected informative markers: Characteristics and properties of Bayesian clustering via STRUCTURE

Prediction of Dopamine Transporter Binding Availability by Genotype: A Preliminary Report

article

Predictors of tanning dependence in white non-Hispanic females and males

scientific article

Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample

scientific article published on 09 August 2012

Pro-opiomelanocortin gene variation related to alcohol or drug dependence: evidence and replications across family- and population-based studies

scientific article

Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls

scientific article

Pstl RFLP at the SERT locus

scientific article published on 01 February 1994

Psychiatric Genomics: An Update and an Agenda

scientific article published on 3 October 2017

Psychiatric Genomics: An Update and an Agenda

Quantitative trait locus analysis identifies rat genomic regions related to amphetamine-induced locomotion and Galpha(i3) levels in nucleus accumbens

scientific article

RDoC and translational perspectives on the genetics of trauma-related psychiatric disorders

scientific article published on 22 November 2015

RGS2 and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults

scientific article published on January 2009

Rare human nicotinic acetylcholine receptor α4 subunit (CHRNA4) variants affect expression and function of high-affinity nicotinic acetylcholine receptors.

scientific article published on 02 January 2014

Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence

scientific article

Rate of progression from first use to dependence on cocaine or opioids: a cross-substance examination of associated demographic, psychiatric, and childhood risk factors

scientific article published on 18 October 2013

Rating the severity and character of transient cocaine-induced delusions and hallucinations with a new instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP).

scientific article published in October 2005

Recessive genetic mode of an ADH4 variant in substance dependence in African-Americans: A model of utility of the HWD test

scientific article published on 18 September 2008

Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA).

scientific article

Reply

Reply

Report of the DNA committee and catalogs of cloned and mapped genes and DNA polymorphisms pp. 892–921

article

Response to Dr. Kopke's comments on haplotypes at the OPRM1 locus

article

Retrospective Association Analysis of Longitudinal Binary Traits Identifies Important Loci and Pathways in Cocaine Use

scientific article published on 07 October 2019

Review: DNA methylation and alcohol use disorders: Progress and challenges

scientific article published on 19 October 2016

Risk factors for cocaine-induced paranoia in cocaine-dependent sibling pairs

scientific article published on 18 January 2006

Role of variation in the serotonin transporter protein gene (SLC6A4) in trait disturbances in the ventral anterior cingulate in bipolar disorder

scientific article

S100A10 identified in a genome-wide gene × cannabis dependence interaction analysis of risky sexual behaviours

scientific article

SLC6A4 polymorphism, population genetics, and psychiatric traits

scientific article published on 03 January 2014

Schizophrenia and substance use comorbidity: a genome-wide perspective

scientific article published on 21 March 2017

Schizophrenia: instability in norepinephrine, serotonin, and gamma-aminobutyric acid systems.

scientific article published on January 1988

Self-efficacy mediates the effects of topiramate and GRIK1 genotype on drinking

scientific article published on 15 December 2014

Sensory gating and psychosis vulnerability in cocaine-dependent individuals: preliminary data

scientific article

Sequence tagged site (STS) TaqI RFLP at dopamine beta-hydroxylase (DBH).

scientific article published on April 1991

Sequence variation and linkage disequilibrium in the GABA transporter-1 gene (SLC6A1) in five populations: implications for pharmacogenetic research

scientific article

Serotonin transporter 5-HTTLPR genotype moderates the effects of childhood adversity on posttraumatic stress disorder risk: a replication study

scientific article

Serotonin transporter gene associations with psychopathic traits in youth vary as a function of socioeconomic resources

scientific article

Serotonin transporter gene promoter polymorphism predicts SSRI response in generalized social anxiety disorder

scientific article

Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects

scientific article published in December 1997

Sex Differences in Methamphetamine Use and Dependence in a Thai Treatment Center

scientific article

Sex-biased methylome and transcriptome in human prefrontal cortex

scientific article published on 24 October 2013

Sex-specific linkage scans in opioid dependence

scientific article

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

scientific article published on 16 February 2020

Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers

scientific article

Social supports and serotonin transporter gene moderate depression in maltreated children

scholarly article

Southeast Asian origins of five Hill Tribe populations and correlation of genetic to linguistic relationships inferred with genome-wide SNP data

scientific article

Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases

scientific article

Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians

scientific article published on 20 November 2011

Substance dependence low-density whole genome association study in two distinct American populations

scientific article

Subtypes of major depression in substance dependence.

scientific article

Suicide, impulsive aggression, and HTR1B genotype.

scientific article published in July 2001

Support for association of RORA variant and post traumatic stress symptoms in a population-based study of hurricane exposed adults

scientific article published on 15 January 2013

Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor

scientific article (publication date: February 2003)

Taql RFLP at norepinephrine transporter protein (NET) locus

scientific article published on 01 June 1993

The A1 allele at the D2 dopamine receptor gene and alcoholism. A reappraisal

scientific article published on April 1993

The D4 dopamine receptor (DRD4) maps to distal 11p close to HRAS

scientific article published on 01 May 1992

The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene

scientific article published on 17 August 2016

The OPRD1 and OPRK1 loci in alcohol or drug dependence: OPRD1 variation modulates substance dependence risk

scientific article

The Research Domain Criteria (RDoC) Project and Studies of Risk and Resilience in Maltreated Children

scientific article (publication date: August 2015)

The association of genetic variation in CACNA1C with structure and function of a frontotemporal system

scientific article published on November 2011

The dopamine transporter protein gene (SLC6A3): primary linkage mapping and linkage studies in Tourette syndrome.

scientific article published on December 1995

The effects of a MAP2K5 microRNA target site SNP on risk for anxiety and depressive disorders

scientific article

The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variation

scientific article

The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores

scientific article published on 14 September 2015

The joint effects of ADH1B variants and childhood adversity on alcohol related phenotypes in African-American and European-American women and men

scientific article published on 19 November 2014

The relationship between risk-taking propensity and the COMT Val(158)Met polymorphism among early adolescents as a function of sex.

scientific article published on 08 May 2012

The role of early life stress in development of the anterior limb of the internal capsule in nonhuman primates

scientific article

The role of genes involved in stress, neural plasticity, and brain circuitry in depressive phenotypes: Convergent findings in a mouse model of neglect

scientific article

The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults.

scientific article published on November 2007

The structure of linkage disequilibrium at the DBH locus strongly influences the magnitude of association between diallelic markers and plasma dopamine beta-hydroxylase activity

scientific article

The validity of cocaine dependence subtypes

scientific article

The variable number of tandem repeats polymorphism of the dopamine transporter gene is not associated with significant change in dopamine transporter phenotype in humans

scientific article

The α-endomannosidase gene (MANEA) is associated with panic disorder and social anxiety disorder

scientific article published on 28 January 2014

Topiramate treatment for heavy drinkers: moderation by a GRIK1 polymorphism

scientific article published on April 2014

Topiramate's reduction of body mass index in heavy drinkers: lack of moderation by a GRIK1 polymorphism

scientific article

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scholarly article published 10 March 2018

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scientific article published on 26 November 2018

Transcriptomic organization of the human brain in post-traumatic stress disorder

scientific article published on 21 December 2020

Transient Cocaine-Associated Behavioral Symptoms Rated with a New Instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP)

article

Translational studies support a role for serotonin 2B receptor (HTR2B) gene in aggression-related cannabis response

article

Trauma exposure interacts with the genetic risk of bipolar disorder in alcohol misuse of US soldiers.

scientific article published on 11 December 2017

Ttn as a likely causal gene for QTL of alcohol preference on mouse chromosome 2

article

Twenty-one-base-pair insertion polymorphism creates an enhancer element and potentiates SLC6A1 GABA transporter promoter activity

scientific article

Typologies of drug dependence: comparative validity of a multivariate and four univariate models

scientific article published in March 2004

Validating Harmful Alcohol Use as a Phenotype for Genetic Discovery Using Phosphatidylethanol and a Polymorphism in ADH1B.

scientific article

Variant callers for next-generation sequencing data: a comparison study

scientific article

Variant detection at the ? opioid receptor (OPRD1) locus and population genetics of a novel variant affecting protein sequence

article

Variant in RGS2 moderates posttraumatic stress symptoms following potentially traumatic event exposure

scientific article published on 25 December 2008

Variation at APOE and STH loci and Alzheimer's disease

scientific article

Variation in GABRA2 predicts drinking behavior in project MATCH subjects

scientific article

Variation in NGFB is associated with primary affective disorders in women

scientific article

Variation in OPRM1 and risk of suicidal behavior in drug-dependent individuals

scientific article published on 15 December 2011

Variation in RGS2 is associated with suicidal ideation in an epidemiological study of adults exposed to the 2004 Florida hurricanes

scientific article published on January 2009

Variation in genes encoding the neuroactive steroid synthetic enzymes 5α-reductase type 1 and 3α-reductase type 2 is associated with alcohol dependence

scientific article

Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes

scientific article

Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses

scientific article

Variation in the gene encoding the serotonin transporter is associated with a measure of sociopathy in alcoholics

scientific article

Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility

scientific article

Which alcohol use disorder criteria contribute to the association of ADH1B with alcohol dependence?

scientific article

Widespread signatures of positive selection in common risk alleles associated to autism spectrum disorder

scientific article

X-chromosome markers and manic-depressive illness. Rejection of linkage to Xq28 in nine bipolar pedigrees

scientific article published in April 1990

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