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List of works by Dirk Haller

15-deoxy-delta12,14-prostaglandin J2-mediated ERK signaling inhibits gram-negative bacteria-induced RelA phosphorylation and interleukin-6 gene expression in intestinal epithelial cells through modulation of protein phosphatase 2A activity

scientific article published on 15 June 2004

A consideration of biomarkers to be used for evaluation of inflammation in human nutritional studies

scientific article published on January 2013

A randomization-based causal inference framework for uncovering environmental exposure effects on human gut microbiota

scientific article published on 09 May 2022

Acetatifactor muris gen. nov., sp. nov., a novel bacterium isolated from the intestine of an obese mouse

scientific article

Activation of human NK cells by staphylococci and lactobacilli requires cell contact-dependent costimulation by autologous monocytes

scientific article published on May 2002

Activation of human peripheral blood mononuclear cells by nonpathogenic bacteria in vitro: evidence of NK cells as primary targets

scientific article published on February 2000

Analysis of factors contributing to variation in the C57BL/6J fecal microbiota across German animal facilities

scientific article

Bacterial proteases in IBD and IBS.

scientific article published on 07 September 2011

Balancing inflammatory, lipid, and xenobiotic signaling pathways by VSL#3, a biotherapeutic agent, in the treatment of inflammatory bowel disease

scientific article published in November 2009

C/EBP homologous protein inhibits tissue repair in response to gut injury and is inversely regulated with chronic inflammation

scientific article published on 21 May 2014

Catechols in caffeic acid phenethyl ester are essential for inhibition of TNF-mediated IP-10 expression through NF-κB-dependent but HO-1- and p38-independent mechanisms in mouse intestinal epithelial cells.

scientific article

Colonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation.

scientific article

Conversion of daidzein and genistein by an anaerobic bacterium newly isolated from the mouse intestine.

scientific article published on 6 June 2008

Critical review: vegetables and fruit in the prevention of chronic diseases

scientific article

Depletion of luminal iron alters the gut microbiota and prevents Crohn's disease-like ileitis.

scientific article published on 12 November 2010

Diet-induced obesity causes metabolic impairment independent of alterations in gut barrier integrity

scientific article published on 20 March 2015

Dietary fat and gut microbiota interactions determine diet-induced obesity in mice

scientific article

Differential effect of immune cells on non-pathogenic Gram-negative bacteria-induced nuclear factor-kappaB activation and pro-inflammatory gene expression in intestinal epithelial cells

scientific article published in June 2004

Differential protein expression profile in the intestinal epithelium from patients with inflammatory bowel disease

scientific article

Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development

scientific article published on 27 July 2016

Dysbiosis in Crohn's disease - Joint action of stochastic injuries and focal inflammation in the gut.

scientific article published on 19 January 2017

Dysbiosis in intestinal inflammation: Cause or consequence

scientific article

Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence.

scientific article published on 17 April 2015

Effects of increase in fish oil intake on intestinal eicosanoids and inflammation in a mouse model of colitis

scientific article published on 31 May 2013

Endoplasmic Reticulum Stress Response Promotes Cytotoxic Phenotype of CD8 + Intraepithelial Lymphocytes in a Mouse Model for Crohn's Disease-like Ileitis

article

Enterococcus faecalis metalloprotease compromises epithelial barrier and contributes to intestinal inflammation

scientific article published on 26 May 2011

Enterococcus faecalis strains differentially regulate Alix/AIP1 protein expression and ERK 1/2 activation in intestinal epithelial cells in the context of chronic experimental colitis.

scientific article

Enterorhabdus caecimuris sp. nov., a member of the family Coriobacteriaceae isolated from a mouse model of spontaneous colitis, and emended description of the genus Enterorhabdus Clavel et al. 2009.

scientific article published on 14 August 2009

Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice

scientific article published on 19 January 2021

Exclusive enteral nutrition in active pediatric Crohn disease: Effects on intestinal microbiota and immune regulation

scientific article published on 15 March 2016

Expression and regulation of the chemokine CXCL16 in Crohnʼs disease and models of intestinal inflammation ⬇️

scientific article published on November 1, 2010

Expression of heparan sulfate proteoglycans in murine models of experimental colitis.

scientific article

Fetal exposure to maternal inflammation does not affect postnatal development of genetically-driven ileitis and colitis

scientific article

Fetal gut laser microdissection in combination with RNA preamplification enables epithelial-specific transcriptional profiling.

scientific article

Gene-environment interaction in chronic disease: a European Science Foundation Forward Look

scientific article published on December 2011

Gene-environment interactions in chronic inflammatory disease

scientific article published on April 2011

Guidance for substantiating the evidence for beneficial effects of probiotics: current status and recommendations for future research

scientific article

Guidance for substantiating the evidence for beneficial effects of probiotics: probiotics in chronic inflammatory bowel disease and the functional disorder irritable bowel syndrome

scientific article published on 27 January 2010

Gut barrier impairment by high-fat diet in mice depends on housing conditions

scientific article published on 17 December 2015

Gut matters: microbe-host interactions in allergic diseases

scientific article published on 08 February 2012

Gut metabolites and bacterial community networks during a pilot intervention study with flaxseeds in healthy adult men.

scientific article published on 5 June 2015

Helicobacter pyloriγ-glutamyltranspeptidase impairs T-lymphocyte function by compromising metabolic adaption through inhibition of cMyc and IRF4 expression

scientific article published on 30 August 2014

High enrichment of MMP-9 and carboxypeptidase A by tweezing adsorptive bubble separation (TABS).

scientific article published on 14 March 2010

High fat diet accelerates pathogenesis of murine Crohn's disease-like ileitis independently of obesity

scientific article

High-fat diet alters gut microbiota physiology in mice

scientific article

IKK beta and phosphatidylinositol 3-kinase/Akt participate in non-pathogenic Gram-negative enteric bacteria-induced RelA phosphorylation and NF-kappa B activation in both primary and intestinal epithelial cell lines

scientific article published on 24 July 2002

IL-10 gene-deficient mice lack TGF-beta/Smad-mediated TLR2 degradation and fail to inhibit proinflammatory gene expression in intestinal epithelial cells under conditions of chronic inflammation

scientific article published on 01 August 2006

IMNGS: A comprehensive open resource of processed 16S rRNA microbial profiles for ecology and diversity studies

scientific article

Identification of an up-regulated anti-apoptotic network in the internal thoracic artery

scientific article

Identification of fitness determinants in Enterococcus faecalis by differential proteomics

scientific article published on 13 December 2012

Impact of a probiotic Enterococcus faecalis in a gnotobiotic mouse model of experimental colitis

scientific article published on 20 January 2011

Induction of dsRNA-activated protein kinase links mitochondrial unfolded protein response to the pathogenesis of intestinal inflammation

scientific article published on 13 October 2011

Innate mechanisms for Bifidobacterium lactis to activate transient pro-inflammatory host responses in intestinal epithelial cells after the colonization of germ-free rats.

scientific article published on August 2005

Integrated microbiota and metabolite profiles link Crohn's disease to sulfur metabolism

scientific article published on 28 August 2020

Interaction between humans and intestinal bacteria as a determinant for intestinal health : intestinal microbiome and inflammatory bowel diseases

scientific article published on February 2015

Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.

scientific article

Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation

scientific article

Intestinal Microbiota in Animal Models of Inflammatory Diseases

scientific article (publication date: 2015)

Intestinal epithelial cell proteome from wild-type and TNFDeltaARE/WT mice: effect of iron on the development of chronic ileitis.

scientific article published in July 2009

Intestinal epithelial cell proteome in IL-10 deficient mice and IL-10 receptor reconstituted epithelial cells: impact on chronic inflammation

scientific article published on 20 July 2007

Intestinal epithelial cell signalling and host-derived negative regulators under chronic inflammation: to be or not to be activated determines the balance towards commensal bacteria.

scientific article

Intestinal microbiota in metabolic diseases: from bacterial community structure and functions to species of pathophysiological relevance

scientific article

Intestinal microbiota: From sequencing to function

scientific article published on 21 February 2016

Intestinal organoids for assessing nutrient transport, sensing and incretin secretion

scientific article

Intestinal steroid profiles and microbiota composition in colitic mice.

scientific article

Intestinimonas butyriciproducens gen. nov., sp. nov., a butyrate-producing bacterium from the mouse intestine.

scientific article

Isolation of bacteria from mouse caecal samples and description of Bacteroides sartorii sp. nov.

scientific article

Isolation of bacteria from the ileal mucosa of TNFdeltaARE mice and description of Enterorhabdus mucosicola gen. nov., sp. nov.

scientific article published on 19 June 2009

Lactocepin as a protective microbial structure in the context of IBD.

scientific article published on 18 January 2013

Lactocepin secreted by Lactobacillus exerts anti-inflammatory effects by selectively degrading proinflammatory chemokines.

scientific article

Loss of Toll-like receptor 2 and 4 leads to differential induction of endoplasmic reticulum stress and proapoptotic responses in the intestinal epithelium under conditions of chronic inflammation.

scientific article

Maternal High-fat Diet Accelerates Development of Crohn's Disease-like Ileitis in TNFΔARE/WT Offspring.

scientific article published on September 2015

Mechanisms of Microbe-Host Interaction in Crohn's Disease: Dysbiosis vs. Pathobiont Selection

scientific article

Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes

scientific article

Metabolic phenotyping of an adoptive transfer mouse model of experimental colitis and impact of dietary fish oil intake

scientific article published on 9 March 2015

Metabolic phenotyping of the Crohn's disease-like IBD etiopathology in the TNF(ΔARE/WT) mouse model

article

Microbe-host interaction in chronic diseases

scientific article published on 24 September 2009

Mitochondria at the interface between danger signaling and metabolism: role of unfolded protein responses in chronic inflammation

scientific article published on 19 December 2011

Mitochondrial function controls intestinal epithelial stemness and proliferation

scientific article published on 27 October 2016

Mitochondrial impairment drives intestinal stem cell transition into dysfunctional Paneth cells predicting Crohn's disease recurrence

scientific article published on 28 February 2020

Modulation of Cytokine Release by Differentiated CACO-2 Cells in a Compartmentalized Coculture Model with Mononuclear Leucocytes and Nonpathogenic Bacteria

scientific article published on 01 November 2004

Molecular crosstalk of probiotic bacteria with the intestinal immune system: clinical relevance in the context of inflammatory bowel disease

scientific article published on 13 October 2009

Multi-omics in IBD biomarker discovery: the missing links

scientific article published on 01 October 2019

Murimonas intestini gen. nov., sp. nov., an acetate-producing bacterium of the family Lachnospiraceae isolated from the mouse gut.

scientific article

Non-pathogenic bacteria elicit a differential cytokine response by intestinal epithelial cell/leucocyte co-cultures

scientific article published on July 2000

Nutrigenomics and IBD: the intestinal microbiota at the cross-road between inflammation and metabolism

scientific article published on 01 September 2010

Nutrigenomics and nutrigenetics in inflammatory bowel diseases

scientific article published on October 2012

On the limits of 16S rRNA gene-based metagenome prediction and functional profiling

scientific article published in 2024

Oral versus intravenous iron replacement therapy distinctly alters the gut microbiota and metabolome in patients with IBD.

scientific article published on 4 February 2016

Orally administered allyl sulfides from garlic ameliorate murine colitis

scientific article published on 21 January 2015

PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins

scientific article published on 10 June 2013

PKR-signaling in DSS-induced colitis: detrime-N-tal or prote-C-tive?

scientific article published in March 2013

Physiological relevance of food grade microcapsules: Impact of milk protein based microcapsules on inflammation in mouse models for inflammatory bowel diseases.

scientific article published on 28 May 2015

Post-translational inhibition of IP-10 secretion in IEC by probiotic bacteria: impact on chronic inflammation

scientific article

Posttranslational inhibition of proinflammatory chemokine secretion in intestinal epithelial cells: implications for specific IBD indications

scientific article published on September 2010

Probiotics and immune response.

scientific article

Properties of myenteric neurones and mucosal functions in the distal colon of diet-induced obese mice

scientific article

Randomized controlled trial on the impact of early-life intervention with bifidobacteria on the healthy infant fecal microbiota and metabolome

scientific article

Reciprocal interaction of diet and microbiome in inflammatory bowel diseases.

scientific article published on 24 September 2015

Reduced microbial diversity and high numbers of one single Escherichia coli strain in the intestine of colitic mice

scientific article

Republished: bacterial proteases in IBD and IBS.

scientific article published on January 2013

Role of the adipocyte-specific NF-κB activity in the regulation of IP-10 and T cell migration

scientific article published on 9 November 2010

Semisynthetic diet ameliorates Crohn's disease-like ileitis in TNFΔARE/WT mice through antigen-independent mechanisms of gluten

scientific article

Septins arrange F-actin-containing fibers on the Chlamydia trachomatis inclusion and are required for normal release of the inclusion by extrusion

scientific article published on 07 October 2014

Streptococcus danieliae sp. nov., a novel bacterium isolated from the caecum of a mouse.

scientific article

Structure-function analysis of the tertiary bile acid TUDCA for the resolution of endoplasmic reticulum stress in intestinal epithelial cells

scientific article published on 14 May 2011

Surface-Associated Lipoproteins Link Enterococcus faecalis Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels

scientific article published on 12 June 2015

The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota

scientific article published on 8 August 2016

The peptide transporter PEPT1 is expressed in distal colon in rodents and humans and contributes to water absorption ⬇️

scientific article published on May 9, 2013

The role of the selenoprotein S (SELS) gene -105G>A promoter polymorphism in inflammatory bowel disease and regulation of SELS gene expression in intestinal inflammation

scientific article (publication date: September 2007)

TheATG16L1Gene Variants rs2241879 and rs2241880 (T300A) Are Strongly Associated With Susceptibility to Crohn's Disease in the German Population

article

Transcriptome analysis of Enterococcus faecalis toward its adaption to surviving in the mouse intestinal tract

scientific article

Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation

scientific article published on 2 April 2003

Unfolded protein responses in the intestinal epithelium: sensors for the microbial and metabolic environment

scientific article published on 01 October 2012

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