List of works by Thomas Pertel

A Versatile Safeguard for Chimeric Antigen Receptor T-Cell Immunotherapies.

scientific article

A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal

scientific article

A pharmacogenetic study implicates SLC9a9 in multiple sclerosis disease activity

scientific article

An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction

scientific article

An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding

scientific article published on 19 January 2009

Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacy.

scientific article published on 9 November 2017

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

scientific journal article

Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells

scientific article published on October 2008

Correction: Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

article

Cyclophilin B interacts with sodium-potassium ATPase and is required for pump activity in proximal tubule cells of the kidney

scientific article

Cyclosporine A-sensitive, cyclophilin B-dependent endoplasmic reticulum-associated degradation

scientific article

Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis

scientific article published on 8 December 2014

Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1

scientific journal article

Erratum: Corrigendum: An IL-27/NFIL3 signalling axis drives Tim-3 and IL–10 expression and T-cell dysfunction

scientific article published in Nature Communications

Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

scientific article

Expression and muscarinic receptor coupling of Lyn kinase in cultured human airway smooth muscle cells

scientific article

Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells

scientific article published in February 2004

HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome

scientific article published on February 2012

ICOS Promotes the Function of CD4+ Effector T Cells during Anti-OX40-Mediated Tumor Rejection

scientific article published on 4 May 2016

IFITM3 inhibits influenza A virus infection by preventing cytosolic entry

scientific article published in October 2011

IFITM3 restricts the morbidity and mortality associated with influenza

scientific article

Impairment of NK cell function by NKG2D modulation in NOD mice

scientific article published in January 2003

Isoproterenol induces actin depolymerization in human airway smooth muscle cells via activation of an Src kinase and GS.

scientific article published in May 2005

Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration

scientific article (publication date: July 2015)

Lv4, an activity that restricts nuclear entry of SIVMAC/SIVSM in human blood cells

scientific article published on 19 September 2013

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1

scientific article

Polarization of migrating monocytic cells is independent of PI 3-kinase activity

scientific article (publication date: 2010)

Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components

scientific article published on 08 September 2009

Reactivation of latent HIV-1 by inhibition of BRD4.

scientific article

Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa

scientific article

TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity

scientific article

TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-kappaB-responsive long terminal repeat elements

scientific article

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

scientific article

TRIM5alpha contributes to the anti-viral state

article by Thomas Pertel et al published 2009 in Retrovirology

The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication

scientific article published on 08 May 2013

Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells

scientific article

Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon

scientific article

p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha

scientific article

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