List of works - Zbynek Bozdech

A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression

scientific article

A comprehensive RNA handling and transcriptomics guide for high-throughput processing of Plasmodium blood-stage samples

scientific article published on 09 October 2020

A crucial piece in the puzzle of the artemisinin resistance mechanism in Plasmodium falciparum

scientific article

A heat-shock response regulated by the PfAP2-HS transcription factor protects human malaria parasites from febrile temperatures

scientific article published on 16 August 2021

A major role for the Plasmodium falciparum ApiAP2 protein PfSIP2 in chromosome end biology

scientific article (publication date: 26 February 2010)

A moonlighting function of Plasmodium falciparum histone 3, mono-methylated at lysine 9?

scientific article (publication date: 19 April 2010)

A role for the protease falcipain 1 in host cell invasion by the human malaria parasite

scientific article (publication date: 6 December 2002)

A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

scientific article

A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria

scientific article

Analysis of subtelomeric virulence gene families in Plasmodium falciparum by comparative transcriptional profiling

scientific article

Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites ⬇️

scientific article published on 11 July 2008

Antioxidant defense in Plasmodium falciparum--data mining of the transcriptome

scientific article

Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription

scientific article

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response

scientific article published on 28 March 2022

Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival

scientific article published on 22 January 2021

Biochemical analysis of the 20 S proteasome of Trypanosoma brucei

scientific article published on 24 February 2003

Cellular thermal shift assay for the identification of drug-target interactions in the Plasmodium falciparum proteome

scientific article published on 27 April 2020

Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitors

scientific article

Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates

scientific article published on 30 October 2009

Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains

scientific article

Crystal structure of the FK506 binding domain of Plasmodium falciparum FKBP35 in complex with FK506

scientific article

DNA damage regulation and its role in drug-related phenotypes in the malaria parasites

scientific article published on April 2016

DNA microarrays for malaria

scientific article published in January 2002

Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes

scientific article

Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai-Myanmar Border (2003-2013): The Role of Parasite Genetic Factors

scientific article published on 16 June 2016

Defining species specific genome differences in malaria parasites

scientific article published on 23 February 2010

Design of a variant surface antigen-supplemented microarray chip for whole transcriptome analysis of multiple Plasmodium falciparum cytoadherent strains, and identification of strain-transcendent rif and stevor genes

scientific article

Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

scientific article

Dynamic epigenetic regulation of gene expression during the life cycle of malaria parasite Plasmodium falciparum

scientific article

Epigenetic landscapes underlining global patterns of gene expression in the human malaria parasite, Plasmodium falciparum

scientific article

Epigenetic memory takes center stage in the survival strategy of malaria parasites.

scientific article

Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray

scientific article

Genome-wide analysis in Plasmodium falciparum reveals early and late phases of RNA polymerase II occupancy during the infectious cycle

scientific article

Genome-wide identification of genes upregulated at the onset of gametocytogenesis in Plasmodium falciparum

article

H2A.Z and H2B.Z double-variant nucleosomes define intergenic regions and dynamically occupy var gene promoters in the malaria parasite Plasmodium falciparum

scientific article published on 4 February 2013

Heterochromatin protein 1 secures survival and transmission of malaria parasites

scientific article (publication date: 13 August 2014)

Histone 4 lysine 8 acetylation regulates proliferation and host-pathogen interaction in Plasmodium falciparum

scientific article published on 22 August 2017

Histone deacetylases play a major role in the transcriptional regulation of the Plasmodium falciparum life cycle

scientific article

Identification of a new chemical class of antimalarials

scientific article

Integrated analysis of the Plasmodium species transcriptome.

scientific article published on 22 April 2016

It is all in your head: a model for cerebral malaria

scholarly article by Antoine Claessens et al published 2010 in Malaria Journal

Molecular approaches to malaria: on the way to integration

scientific article

New insights into the Plasmodium vivax transcriptome using RNA-Seq

scientific article published on 9 February 2016

Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites.

scientific article published on 14 March 2018

Plasmodium falciparum STEVOR proteins are highly expressed in patient isolates and located in the surface membranes of infected red blood cells and the apical tips of merozoites

scientific article published on 12 May 2008

Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors

scientific article published in September 2009

Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites

scientific article published on 17 December 2008

Quantitative proteomics reveals new insights into erythrocyte invasion by Plasmodium falciparum ⬇️

scientific article

Quantitative time-course profiling of parasite and host cell proteins in the human malaria parasite Plasmodium falciparum

scientific article

Role of calcium signaling in the transcriptional regulation of the apicoplast genome of Plasmodium falciparum

scientific article (publication date: 2014)

Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy

scientific article

Singapore Malaria Network Meeting (SingMalNet) 2016.

scientific article published in June 2017

Spread of artemisinin resistance in Plasmodium falciparum malaria

scientific article published on 31 July 2014

Stochastic expression of invasion genes in Plasmodium falciparum schizonts

scientific article published on 30 May 2022

Structural polymorphism in the promoter ofpfmrp2confersPlasmodium falciparumtolerance to quinoline drugs

scientific article (publication date: March 2014)

Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance

scientific article (publication date: April 2015)

The genomics of malaria infection

scientific article

The human malaria parasite Plasmodium falciparum exports the ATP-binding cassette protein PFGCN20 to membrane structures in the host red blood cell

scientific article

The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites

scholarly article

The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum

scientific article published in October 2003

Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum

scientific article (publication date: 2010)

Transcriptional variation in the malaria parasite Plasmodium falciparum

scientific article published on 13 March 2012

Transcriptomics and proteomics

scientific article published on 23 December 2016

List of works by Zbynek Bozdech

A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression

A comprehensive RNA handling and transcriptomics guide for high-throughput processing of Plasmodium blood-stage samples

A crucial piece in the puzzle of the artemisinin resistance mechanism in Plasmodium falciparum

A heat-shock response regulated by the PfAP2-HS transcription factor protects human malaria parasites from febrile temperatures

A major role for the Plasmodium falciparum ApiAP2 protein PfSIP2 in chromosome end biology

A moonlighting function of Plasmodium falciparum histone 3, mono-methylated at lysine 9?

A role for the protease falcipain 1 in host cell invasion by the human malaria parasite

A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria

Analysis of subtelomeric virulence gene families in Plasmodium falciparum by comparative transcriptional profiling

Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites ⬇️

Antioxidant defense in Plasmodium falciparum--data mining of the transcriptome

Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response

Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival

Biochemical analysis of the 20 S proteasome of Trypanosoma brucei

Cellular thermal shift assay for the identification of drug-target interactions in the Plasmodium falciparum proteome

Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitors

Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates

Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains

Crystal structure of the FK506 binding domain of Plasmodium falciparum FKBP35 in complex with FK506

DNA damage regulation and its role in drug-related phenotypes in the malaria parasites

DNA microarrays for malaria

Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes

Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai-Myanmar Border (2003-2013): The Role of Parasite Genetic Factors

Defining species specific genome differences in malaria parasites

Design of a variant surface antigen-supplemented microarray chip for whole transcriptome analysis of multiple Plasmodium falciparum cytoadherent strains, and identification of strain-transcendent rif and stevor genes

Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

Dynamic epigenetic regulation of gene expression during the life cycle of malaria parasite Plasmodium falciparum

Epigenetic landscapes underlining global patterns of gene expression in the human malaria parasite, Plasmodium falciparum

Epigenetic memory takes center stage in the survival strategy of malaria parasites.

Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray

Genome-wide analysis in Plasmodium falciparum reveals early and late phases of RNA polymerase II occupancy during the infectious cycle

Genome-wide identification of genes upregulated at the onset of gametocytogenesis in Plasmodium falciparum

H2A.Z and H2B.Z double-variant nucleosomes define intergenic regions and dynamically occupy var gene promoters in the malaria parasite Plasmodium falciparum

Heterochromatin protein 1 secures survival and transmission of malaria parasites

Histone 4 lysine 8 acetylation regulates proliferation and host-pathogen interaction in Plasmodium falciparum

Histone deacetylases play a major role in the transcriptional regulation of the Plasmodium falciparum life cycle

Identification of a new chemical class of antimalarials

Integrated analysis of the Plasmodium species transcriptome.

It is all in your head: a model for cerebral malaria

Molecular approaches to malaria: on the way to integration

New insights into the Plasmodium vivax transcriptome using RNA-Seq

Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites.

Plasmodium falciparum STEVOR proteins are highly expressed in patient isolates and located in the surface membranes of infected red blood cells and the apical tips of merozoites

Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors

Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites

Quantitative proteomics reveals new insights into erythrocyte invasion by Plasmodium falciparum ⬇️

Quantitative time-course profiling of parasite and host cell proteins in the human malaria parasite Plasmodium falciparum

Role of calcium signaling in the transcriptional regulation of the apicoplast genome of Plasmodium falciparum

Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy

Singapore Malaria Network Meeting (SingMalNet) 2016.

Spread of artemisinin resistance in Plasmodium falciparum malaria

Stochastic expression of invasion genes in Plasmodium falciparum schizonts

Structural polymorphism in the promoter ofpfmrp2confersPlasmodium falciparumtolerance to quinoline drugs

Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance

The genomics of malaria infection

The human malaria parasite Plasmodium falciparum exports the ATP-binding cassette protein PFGCN20 to membrane structures in the host red blood cell

The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites

The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum

Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum

Transcriptional variation in the malaria parasite Plasmodium falciparum

Transcriptomics and proteomics