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List of works by Matthias Kretzler

A Multicenter Randomized Controlled Trial of Rituximab versus Cyclosporine in the Treatment of Idiopathic Membranous Nephropathy (MENTOR).

scientific article

A Transcriptional Map of the Renal Tubule: Linking Structure to Function.

scientific article published on 27 March 2015

A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation

scientific article

A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians

scientific article published on 6 February 2015

A cognitive task analysis of a visual analytic workflow: Exploring molecular interaction networks in systems biology ⬇️

scientific article published on March 21, 2011

A molecular morphometric approach to diabetic kidney disease can link structure to function and outcome.

scientific article

A molecular profile of focal segmental glomerulosclerosis from formalin-fixed, paraffin-embedded tissue ⬇️

scientific article

A molecular signature of proteinuria in glomerulonephritis

scientific article

A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy

scientific article published on 20 February 2017

A pilot study of gene expression-based categorization of pancreas transplant biopsies

scientific article published on January 2009

A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease

scientific article

A reference panel of 64,976 haplotypes for genotype imputation

scientific article

A role for NPY-NPY2R signaling in albuminuric kidney disease

scientific article published on 19 June 2020

A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis

scientific article published on 22 February 2016

A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis

scientific article published on March 2016

A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes

scientific article published on 22 April 2019

A systems approach to renal inflammation in SLE.

scientific article

A systems view of genetics in chronic kidney disease ⬇️

scientific article published on October 19, 2011

A unique hybrid renal mononuclear phagocyte activation phenotype in murine systemic lupus erythematosus nephritis

scientific article

APOL1-associated glomerular disease among African-American children: a collaboration of the Chronic Kidney Disease in Children (CKiD) and Nephrotic Syndrome Study Network (NEPTUNE) cohorts

scientific article published on 27 April 2016

ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes

scientific article published on 22 July 2019

Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1.

scientific article

Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated nephropathy.

scientific article published on 14 September 2011

Activation of toll-like receptor-9 induces progression of renal disease in MRL-Fas(lpr) mice

scientific article published on 20 January 2004

Alpha-actinin-4 and CLP36 protein deficiencies contribute to podocyte defects in multiple human glomerulopathies

scientific article

Alteration of forkhead box O (foxo4) acetylation mediates apoptosis of podocytes in diabetes mellitus

scientific article

Alterations in the ubiquitin proteasome system in persistent but not reversible proteinuric diseases

scientific article

An Outcomes-Based Definition of Proteinuria Remission in Focal Segmental Glomerulosclerosis.

scientific article published on 22 November 2017

An atlas of healthy and injured cell states and niches in the human kidney ⬇️

An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome

scientific article published on 26 July 2018

An integrative systems biology approach for precision medicine in diabetic kidney disease

scientific article published on 01 October 2018

Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex

scientific article

BASP1 promotes apoptosis in diabetic nephropathy.

scientific article

BK virus associated nephropathy in native kidneys of a heart allograft recipient

scientific article

Bacterial CpG-DNA aggravates immune complex glomerulonephritis: role of TLR9-mediated expression of chemokines and chemokine receptors.

scientific article

Bcl-2–Modifying Factor Induces Renal Proximal Tubular Cell Apoptosis in Diabetic Mice ⬇️

scientific article published on December 30, 2011

Binding of the chemokine SLC/CCL21 to its receptor CCR7 increases adhesive properties of human mesangial cells

scientific article

Bioinformatic analysis of the urine proteome of acute allograft rejection

scientific article

Blood Pressure and Visit-to-Visit Blood Pressure Variability Among Individuals With Primary Proteinuric Glomerulopathies

scientific article

Bone morphogenetic protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis

scientific article

CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome

scientific article published in December 2004

CD20-positive infiltrates in human membranous glomerulonephritis

scientific article published on 01 May 2005

COVID-19 and Diabetes: A Collision and Collusion of Two Diseases

scientific article published on 16 September 2020

CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis

scientific article

Cell biology of the glomerular podocyte

scientific article

Changes in Albuminuria But Not GFR are Associated with Early Changes in Kidney Structure in Type 2 Diabetes

scientific article published on 01 June 2019

Characterization of a Na(+)-Ca(2+) exchanger in podocytes

scientific article published in October 2002

Chemokine receptor CCR1 but not CCR5 mediates leukocyte recruitment and subsequent renal fibrosis after unilateral ureteral obstruction

scientific article published on 01 February 2004

Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study

scientific article published on 03 August 2018

Co-regulation of Gremlin and Notch signalling in diabetic nephropathy

scientific article published on 11 October 2007

Comparative RNA-Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease.

scientific article

Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins

scholarly article

Comparative transcriptional profiling of 3 murine models of SLE nephritis reveals both unique and shared regulatory networks

scientific article

Complete Remission in the Nephrotic Syndrome Study Network

scientific article

Consent for Genetic Biobanking in a Diverse Multisite CKD Cohort

scientific article published on 12 June 2018

Correlation Between Baseline GFR and Subsequent Change in GFR in Norwegian Adults Without Diabetes and in Pima Indians

scientific article published on 28 January 2019

Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis

scientific article

CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease

scientific article published on 09 November 2018

Cyclodextrin protects podocytes in diabetic kidney disease

scientific article published on 08 July 2013

Decoding the genetic determinants of gene regulation in the kidney

scientific article published on 01 January 2019

Decrease and gain of gene expression are equally discriminatory markers for prostate carcinoma: a gene expression analysis on total and microdissected prostate tissue

scientific article

Defining Glomerular Disease in Mechanistic Terms: Implementing an Integrative Biology Approach in Nephrology

scientific article published on 14 September 2016

Defining Renal Neoplastic Disease, One Cell at a Time: Mass Cytometry, a New Tool for the Study of Kidney Biology and Disease

scientific article published on 11 October 2017

Defining cell-type specificity at the transcriptional level in human disease

scientific article published on 15 August 2013

Defining human diabetic nephropathy on the molecular level: integration of transcriptomic profiles with biological knowledge

scientific article published on December 2008

Defining nephrotic syndrome from an integrative genomics perspective

scientific article

Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease.

scientific article

Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach

scientific article published on 16 January 2013

Diabetic nephropathy: a national dialogue

scientific article published on 20 June 2013

Differential expression of profibrotic and growth factors in chronic allograft nephropathy

scientific article published on 01 February 2006

Differential regulation of chemokine CCL5 expression in monocytes/macrophages and renal cells by Y-box protein-1

scientific article published on 17 September 2008

Differentially spliced isoforms of FAT1 are asymmetrically distributed within migrating cells

scientific journal article

Digital pathology evaluation in the multicenter Nephrotic Syndrome Study Network (NEPTUNE)

scientific article

Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology

scientific article

Discovering hidden relationships between renal diseases and regulated genes through 3D network visualizations

scientific article

Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury

scientific article published on 15 May 2013

Early glomerular filtration defect and severe renal disease in podocin-deficient mice

scientific article

Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy

scientific article

Erratum to: Evaluating Mendelian nephrotic syndrome genes for evidence for risk alleles or oligogenicity that explain heritability

article

Estimated GFR Trajectories in Pediatric and Adult Nephrotic Syndrome: Results From the Nephrotic Syndrome Study Network (NEPTUNE)

scientific article published on 05 June 2020

Evaluating Mendelian nephrotic syndrome genes for evidence for risk alleles or oligogenicity that explain heritability

scientific article published on 20 October 2016

Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice

scientific article

Expression of filtrin in human glomerular diseases

scientific article published on 18 April 2007

Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy

scientific article published in June 2005

Expression of the chemokine receptor CCR1 in human renal allografts

scientific article published on 13 February 2007

FAR2 is Associated with Kidney Disease in Mice and Humans.

scientific article

FSGS as an Adaptive Response to Growth-Induced Podocyte Stress

scientific article

Fibroblast growth factor 23 and Inflammation in CKD ⬇️

scientific article published on May 3, 2012

Fn14 in podocytes and proteinuric kidney disease.

scientific article

Formal concept analysis of disease similarity ⬇️

scientific article published on March 19, 2012

Formation and phosphorylation of the PINCH-1-integrin linked kinase-alpha-parvin complex are important for regulation of renal glomerular podocyte adhesion, architecture, and survival

scientific article

From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy

scientific article

From single nucleotide polymorphism to transcriptional mechanism: a model for FRMD3 in diabetic nephropathy

scientific article published on 22 February 2013

From the Large Scale Expression Analysis of Lupus Nephritis to Targeted Molecular Medicine

scientific article published on March 2012

Functional consequences of integrin-linked kinase activation in podocyte damage

scientific article

GDF-15, Galectin 3, Soluble ST2, and Risk of Mortality and Cardiovascular Events in CKD

scientific article published on 14 June 2018

Gene Expression Profiles of Podocyte-Associated Molecules as Diagnostic Markers in Acquired Proteinuric Diseases ⬇️

scientific article published on November 1, 2003

Gene expression analysis in microdissected renal tissue. Current challenges and strategies

scientific article published on 01 January 2002

Gene expression analysis in renal biopsies

scientific article published on 19 March 2004

Gene expression analysis of human renal biopsies: recent developments towards molecular diagnosis of kidney disease

scientific article published on May 2004

Gene expression fingerprints in human tubulointerstitial inflammation and fibrosis as prognostic markers of disease progression.

scientific article published in March 2004

Gene expression profiling analysis in nephrology: towards molecular definition of renal disease

scientific article

Gene-expression analysis of microdissected renal biopsies.

scientific article

Gene-level integrated metric of negative selection (GIMS) prioritizes candidate genes for nephrotic syndrome

scientific article

Genetic and environmental risk factors for chronic kidney disease

scientific article published on 20 September 2017

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen

scientific article published on 19 September 2019

Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)

scientific article published on 25 August 2015

Genomic analysis in nephrology--towards systems biology and systematic medicine?

scientific article published on 30 June 2008

Genomic biomarkers for chronic kidney disease.

scientific article published on 9 February 2012

Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy

scientific article published on 20 April 2017

Glomerular disease: Personalized immunomonitoring in lupus and lupus nephritis.

scientific article published on 9 May 2016

Glomerular podocytes contain neuron-like functional synaptic vesicles

scientific article published on 03 April 2006

Glomerular podocytes in kidney health and disease

scientific article published on 01 March 2019

Glomerular podocytes possess the synaptic vesicle molecule Rab3A and its specific effector rabphilin-3a

scientific article

Growth Differentiation Factor-15 and Risk of CKD Progression

scientific article published on 3 February 2017

Health-related quality of life in glomerular disease

scientific article published on 27 February 2019

High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping

scientific article published on 17 May 2018

How to build a tight but permeable glomerular junction.

scientific article

Human nephrosclerosis triggers a hypoxia-related glomerulopathy

scientific article

Hydroxypropyl-β-cyclodextrin protects from kidney disease in experimental Alport syndrome and focal segmental glomerulosclerosis

scientific article published on 06 October 2018

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

scientific article

IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis.

scientific article published on 28 May 2008

Identification of Cross-Species Shared Transcriptional Networks of Diabetic Nephropathy in Human and Mouse Glomeruli ⬇️

scientific article published on November 8, 2012

Identification of a signal transduction pathway that regulates MMP-9 mRNA expression in glomerular injury

scientific article published on July 2002

Identification of dicarbonyl and L-xylulose reductase as a therapeutic target in human chronic kidney disease

scientific article published on 20 June 2019

Identification of glomerular and podocyte-specific genes and pathways activated by sera of patients with focal segmental glomerulosclerosis

scientific article published on 03 October 2019

Identification of nephropathy candidate genes by comparing sclerosis-prone and sclerosis-resistant mouse strain kidney transcriptomes

scientific article

Identification of stage-specific genes associated with lupus nephritis and response to remission induction in (NZB × NZW)F1 and NZM2410 mice.

scientific article

Identification of stage-specific genes associated with lupus nephritis and response to remission induction in NZB/W and NZM2410 mice.

scientific article published on 18 September 2014

Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis

scientific article

Increased lipogenesis and impaired β-oxidation predict type 2 diabetic kidney disease progression in American Indians

scientific article published on 01 November 2019

Induction of B7-1 in podocytes is associated with nephrotic syndrome

scientific article

Induction of B7-1 in podocytes is associated with nephrotic syndrome

article by Jochen Reiser et al published 15 May 2004 in Journal of Clinical Investigation

Induction of TRPC6 channel in acquired forms of proteinuric kidney disease

scientific article published on 13 December 2006

Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus

scientific article published on 4 November 2011

Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease

scientific article published on 22 December 2016

Influence of native and hypochlorite-modified low-density lipoprotein on gene expression in human proximal tubular epithelium

scientific article

Integrated multi-omics approaches to improve classification of chronic kidney disease

scientific article published on 18 May 2020

Integrating automated workflows, human intelligence and collaboration ⬇️

scientific article published on March 1, 2009

Integrative Biology of Diabetic Kidney Disease

scientific article published on 23 September 2015

Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects

scientific article published on 6 July 2015

Integrative analysis of prognostic biomarkers derived from multiomics panels helps discrimination of chronic kidney disease trajectories in people with type 2 diabetes

scientific article published on 30 August 2019

Integrative biology identifies shared transcriptional networks in CKD.

scientific article

Integrative biology of renal disease: toward a holistic understanding of the kidney's function and failure ⬇️

scientific article published on September 1, 2010

Integrin-linked kinase in renal disease: connecting cell-matrix interaction to the cytoskeleton

scientific article

Interaction of DAP3 and FADD only after cellular disruption

scientific article (publication date: 2002)

Interstitial fibrosis scored on whole-slide digital imaging of kidney biopsies is a predictor of outcome in proteinuric glomerulopathies.

scientific article published on 27 February 2017

Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy.

scientific article published on 2 May 2007

Intrarenal production of B-cell survival factors in human lupus nephritis ⬇️

scientific article published on October 1, 2010

Introduction: Precision Medicine for Glomerular Disease: The Road Forward.

scientific article

JAK inhibition in the treatment of diabetic kidney disease

scientific article published on 22 June 2016

JAK-STAT Activity in Peripheral Blood Cells and Kidney Tissue in IgA Nephropathy

scientific article published on 30 April 2020

JAK-STAT signaling is activated in the kidney and peripheral blood cells of patients with focal segmental glomerulosclerosis

scientific article published on 06 August 2018

JAK1/JAK2 inhibition by baricitinib in diabetic kidney disease: results from a Phase 2 randomized controlled clinical trial

scientific article published on 22 February 2018

Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins ⬇️

scientific article published on February 15, 2011

LRG1 Promotes Diabetic Kidney Disease Progression by Enhancing TGF-β-Induced Angiogenesis

scientific article published on 11 March 2019

Laser microdissection and gene expression analysis on formaldehyde-fixed archival tissue

scientific article

Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice

scientific article

Linking variants from genome-wide association analysis to function via transcriptional network analysis

scientific article published on March 2010

Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury

scientific article published on 02 August 2016

Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines

scientific article

Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease

scientific article

Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice

scientific article published on 13 August 2006

Low levels of urinary epidermal growth factor predict chronic kidney disease progression in children

scientific article published on 20 March 2019

Lupus nephritis susceptibility loci in women with systemic lupus erythematosus

scientific article

Machine learning, the kidney, and genotype-phenotype analysis

scientific article published on 01 April 2020

Maternal environment interacts with modifier genes to influence progression of nephrotic syndrome

scientific article published on 2 April 2008

Metabolic pathways and immunometabolism in rare kidney diseases

scientific article published on 03 May 2018

Metabolomics and Gene Expression Analysis Reveal Down-regulation of the Citric Acid (TCA) Cycle in Non-diabetic CKD Patients

scientific article published on 31 October 2017

Micro-dissection and integration of long and short reads to create a robust catalog of kidney compartment-specific isoforms

scientific article published on 25 April 2022

MicroRNA-21 in glomerular injury

scientific article

Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project

scientific article published on 16 September 2020

Modification of kidney barrier function by the urokinase receptor.

scientific article published on 16 December 2007

Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog.

scientific article published in August 2003

Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy

scientific article published on 01 November 2006

Molecular Profiling of Cutaneous Lupus Lesions Identifies Subgroups Distinct from Clinical Phenotypes

scientific article published on 17 August 2019

Molecular approaches to chronic kidney disease

scientific article

Molecular studies of lupus nephritis kidneys

scientific article published on 16 September 2015

Mouse models of diabetic nephropathy

scientific article

MultiPLIER: A Transfer Learning Framework for Transcriptomics Reveals Systemic Features of Rare Disease

scientific article published on 01 May 2019

MultiPLIER: a transfer learning framework reveals systemic features of rare autoimmune disease

Myeloperoxidase Levels and Its Product 3-Chlorotyrosine Predict Chronic Kidney Disease Severity and Associated Coronary Artery Disease

scientific article published in July 2017

NFkappaB promotes inflammation, coagulation, and fibrosis in the aging glomerulus

scientific article

Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus.

scientific article

Network analysis of genes regulated in renal diseases: implications for a molecular-based classification

scientific article

New immunosuppressive strategies in renal transplant recipients.

scientific article published on January 2004

New susceptibility loci associated with kidney disease in type 1 diabetes

scientific article

Nomenclature for kidney function and disease: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference

scientific article published on 09 March 2020

Notch inhibition reverses kidney failure

scientific article published on 01 March 2008

Novel Role of Toll-Like Receptor 3 in Hepatitis C-Associated Glomerulonephritis

scientific article (publication date: February 2006)

Novel avenues for drug discovery in diabetic kidney disease

scientific article published on 16 November 2017

ORAI channels are critical for receptor-mediated endocytosis of albumin.

scientific article published on 4 December 2017

Opponent's comments

scientific article published on 01 June 2015

Organoid single cell profiling identifies a transcriptional signature of glomerular disease

scientific article published on 10 January 2019

PDGF-C Expression in the Developing and Normal Adult Human Kidney and in Glomerular Diseases ⬇️

scientific article published on May 1, 2003

Palladin is a dynamic actin-associated protein in podocytes

scientific article

Pathogenetic Mechanisms in Lupus Nephritis

Periostin is induced in glomerular injury and expressed de novo in interstitial renal fibrosis

scientific article

Perspectives on Systems Biology Applications in Diabetic Kidney Disease ⬇️

scientific article published on June 26, 2012

Podocyte-specific JAK2 overexpression worsens diabetic kidney disease in mice.

scientific article

Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis.

scientific article

Polyomavirus DNA and RNA detection in renal allograft biopsies: results from a European multicenter study

scientific article published on 01 September 2005

Post‐translational and cell type‐specific regulation of CXCR4 expression by cytokines ⬇️

scientific article published on November 1, 2003

Prognostic imaging biomarkers for diabetic kidney disease (iBEAt): study protocol

scientific article published on 29 June 2020

Proteinuria and hyperglycemia induce endoplasmic reticulum stress

scientific article

Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease

scientific article published in August 2007

Proteome Analysis of Isolated Podocytes Reveals Stress Responses in Glomerular Sclerosis

scientific article published on 11 February 2020

Proteomic Analysis Identifies Distinct Glomerular Extracellular Matrix in Collapsing Focal Segmental Glomerulosclerosis

scientific article published on 19 June 2020

Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis

scientific article published on 01 October 2019

Quantitative gene expression analysis in renal biopsies: a novel protocol for a high-throughput multicenter application

scientific article published on 01 January 2002

Reduced intragraft mRNA expression of matrix metalloproteinases Mmp3, Mmp12, Mmp13 and Adam8, and diminished transplant arteriosclerosis in Ccr5-deficient mice

scientific article published on 01 September 2004

Regulation of adhesive interaction between podocytes and glomerular basement membrane

scientific article

Renal Pre-Competitive Consortium (RPC2): discovering therapeutic targets together

scientific article published on 18 May 2018

Renal SGLT mRNA expression in human health and disease: a study in two cohorts

scientific article published on 23 September 2019

Renal biopsy-driven molecular target identification in glomerular disease

scientific article

Renal gene and protein expression signatures for prediction of kidney disease progression

scientific article

Renal matrix Gla protein expression increases progressively with CKD and predicts renal outcome

scientific article published on 06 July 2018

Reproducibility of the NEPTUNE descriptor-based scoring system on whole-slide images and histologic and ultrastructural digital images

scientific article

Repuncturing the renal biopsy: strategies for molecular diagnosis in nephrology.

scientific article

Research capacity. Enabling the genomic revolution in Africa

scientific article published in June 2014

Role of basic fibroblast growth factor (FGF-2) in diabetic nephropathy and mechanisms of its induction by hyperglycemia in human renal fibroblasts

scientific article published on 11 March 2009

Role of endothelin receptors for renal protection and survival in hypertension: waiting for clinical trials

scientific article published on 02 October 2006

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

scientific article

Role of podocytes for reversal of glomerulosclerosis and proteinuria in the aging kidney after endothelin inhibition.

scientific article published on 15 November 2004

Role of podocytes in focal sclerosis: defining the point of no return

scientific article published on 07 September 2005

Roles of PINCH-2 in regulation of glomerular cell shape change and fibronectin matrix deposition

scientific article published on 14 May 2008

Roles of SLC/CCL21 and CCR7 in human kidney for mesangial proliferation, migration, apoptosis, and tissue homeostasis

scientific article (publication date: May 2002)

Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy.

scientific article published on 30 July 2008

Rosiglitazone treatment reduces diabetic neuropathy in streptozotocin-treated DBA/2J mice

scientific article published on 26 June 2008

SARS-CoV-2 receptor networks in diabetic and COVID-19 associated kidney disease

scientific article published on 07 October 2020

SARS-CoV-2 receptor networks in diabetic kidney disease, BK-Virus nephropathy and COVID-19 associated acute kidney injury

scientific article published on 13 May 2020

Sam68-like mammalian protein 2, identified by digital differential display as expressed by podocytes, is induced in proteinuria and involved in splice site selection of vascular endothelial growth factor

scientific article published on 18 May 2005

Serum amyloid A and Janus kinase 2 in a mouse model of diabetic kidney disease

scientific article published on 14 February 2019

Shared and distinct lipid-lipid interactions in plasma and affected tissues in a diabetic mouse model.

scientific article published on 13 December 2017

Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker

scientific article published on 26 March 2020

Single-Cell Sequencing the Glomerulus, Unraveling the Molecular Programs of Glomerular Filtration, One Cell at a Time

scientific article published on 12 July 2018

Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney

scientific article published on 30 August 2018

Soluble RARRES1 induces podocyte apoptosis to promote glomerular disease progression

scientific article published on 07 July 2020

Soluble ST2 and Galectin-3 and Progression of CKD

scientific article published on 21 September 2018

Spatial and temporally restricted expression of chemokines and chemokine receptors in the developing human kidney.

scientific article

Sphingomyelinase-like phosphodiesterase 3b expression levels determine podocyte injury phenotypes in glomerular disease

scientific article

Stra13, a prostaglandin E2-induced gene, regulates the cellular redox state of podocytes

scientific article published on 19 February 2003

Strategies to improve monitoring disease progression, assessing cardiovascular risk, and defining prognostic biomarkers in chronic kidney disease

Strategy and rationale for urine collection protocols employed in the NEPTUNE study

scientific article published on 17 November 2015

Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset

scientific article

Systematically differentiating functions for alternatively spliced isoforms through integrating RNA-seq data

scientific article

Systems Biology and Kidney Disease

scientific article published on 28 January 2020

Systems biology analysis reveals role of MDM2 in diabetic nephropathy

scientific article (publication date: 20 October 2016)

Systems biology approaches to identify disease mechanisms and facilitate targeted therapy in the management of glomerular disease

scientific article published on 01 November 2018

TGF-beta1 regulates the PINCH-1-integrin-linked kinase-alpha-parvin complex in glomerular cells

scientific journal article

TRAIL-induced apoptosis is independent of the mitochondrial apoptosis mediator DAP3

scientific article (publication date: 4 October 2002)

Targeted Lipidomic and Transcriptomic Analysis Identifies Dysregulated Renal Ceramide Metabolism in a Mouse Model of Diabetic Kidney Disease

scientific article

Targeted glomerular angiopoietin-1 therapy for early diabetic kidney disease.

scientific article published on 5 September 2013

The MIF receptor CD74 in diabetic podocyte injury

scientific article published on 08 October 2008

The Metabolic Syndrome and Microvascular Complications in a Murine Model of Type 2 Diabetes.

scientific article

The NIH National Center for Integrative Biomedical Informatics (NCIBI).

scientific article published on 19 November 2011

The contribution of B cells to renal interstitial inflammation

scientific article published on February 2007

The death ligand TRAIL in diabetic nephropathy

scientific article published on 20 February 2008

The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction

scientific article

The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis

scientific article published on 30 March 2020

The identification of gene expression profiles associated with progression of human diabetic neuropathy

scientific article published on 16 September 2011

The immune cell landscape in kidneys of patients with lupus nephritis

scientific article published on 17 June 2019

The longitudinal relationship between patient-reported outcomes and clinical characteristics among patients with focal segmental glomerulosclerosis in the Nephrotic Syndrome Study Network

scientific article published on 05 August 2019

The molecular phenotype of endocapillary proliferation: novel therapeutic targets for IgA nephropathy

scientific article

The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus.

scientific article published on 20 July 2009

The peroxisome-proliferator activated receptor-γ agonist pioglitazone modulates aberrant T cell responses in systemic lupus erythematosus

scientific article

The relatively poor correlation between random and 24-hour urine protein excretion in patients with biopsy-proven glomerular diseases

scientific article published on 12 August 2016

The role of bone morphogenetic protein-5 (BMP-5) in human nephrosclerosis ⬇️

scientific article published on September 1, 2011

The role of renin-angiotensin-aldosterone system genes in the progression of chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) study ⬇️

scientific article published on 23 April 2015

The ubiquitin-like protein FAT10 mediates NF-kappaB activation

scientific article

Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker

scientific article published on December 2015

Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications

scientific article published on 22 September 2016

Toll-like receptor-4: renal cells and bone marrow cells signal for neutrophil recruitment during pyelonephritis.

scientific article

Toll-like receptor-7 modulates immune complex glomerulonephritis

scientific article published on 9 November 2005

Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays

scientific article

Transcriptional networks of murine diabetic peripheral neuropathy and nephropathy: common and distinct gene expression patterns.

scientific article published on 21 March 2016

Transcriptional profiling of diabetic neuropathy in the BKS db/db mouse: a model of type 2 diabetes.

scientific article

Transcriptome analysis of primary podocytes reveals novel calcium regulated regulatory networks

scientific article published on 15 September 2020

Transcriptome analysis of proximal tubular cells (HK-2) exposed to urines of type 1 diabetes patients at risk of early progressive renal function decline

scientific article

Transcriptome-based network analysis reveals renal cell type-specific dysregulation of hypoxia-associated transcripts

scientific article

Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy

scientific article

Transethnic, Genome-Wide Analysis Reveals Immune-Related Risk Alleles and Phenotypic Correlates in Pediatric Steroid-Sensitive Nephrotic Syndrome

scientific article published on 14 June 2018

Tyro3 is a podocyte protective factor in glomerular disease

scientific article published on 15 November 2018

Upregulation of Tumor Susceptibility Gene 101 (TSG101) by mechanical stress in podocytes

scientific article published on 31 January 2019

Urinary Epidermal Growth Factor as a Marker of Disease Progression in Children With Nephrotic Syndrome

scientific article published on 05 December 2019

Urinary Epidermal Growth Factor/Creatinine Ratio and Graft Failure in Renal Transplant Recipients: A Prospective Cohort Study

scientific article published on 13 October 2019

Urinary epidermal growth factor as a prognostic marker for the progression of Alport syndrome in children

Urinary epidermal growth factor predicts renal prognosis in antineutrophil cytoplasmic antibody-associated vasculitis

scientific article published on 03 May 2018

Urinary excretion of epidermal growth factor and rapid loss of kidney function

scientific article published on 17 October 2020

Urine glycoprotein profile reveals novel markers for chronic kidney disease

scientific article

Urine podocyte mRNAs mark progression of renal disease

scientific article published on 23 April 2009

Using Population Genetics to Interrogate the Monogenic Nephrotic Syndrome Diagnosis in a Case Cohort

scientific article

Validation of Plasma Biomarker Candidates for the Prediction of eGFR Decline in Patients With Type 2 Diabetes

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Validation of endogenous controls for gene expression analysis in microdissected human renal biopsies

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Vascular endothelial growth factor production and regulation in human peritoneal mesothelial cells

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Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor 3 on glomerular mesangial cells and antigen-presenting cells

scientific article published on 16 March 2005

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

scientific article published on 23 May 2011

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