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List of works by Helle Krogh Johansen

A cohort study of the Copenhagen CF Centre eradication strategy against Staphylococcus aureus in patients with CF ⬇️

scientific article published on July 10, 2012

A novel knee prosthesis model of implant-related osteomyelitis in rats

scientific article published on February 2013

Active and Passive Immunization Against Staphylococcus aureus Periprosthetic Osteomyelitis in Rats

scientific article published on January 2017

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

scientific article

Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients

scientific article published on 16 October 2019

Alpha1-antitrypsin deficiency

scientific article published on 01 November 2009

Amphotericin B lipid soluble formulations versus amphotericin B in cancer patients with neutropenia

scientific article

Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients

scientific article

An exploratory study of microbial diversity in sinus infections of cystic fibrosis patients by molecular methods

scientific article

Antibiofilm Properties of Acetic Acid

scientific article published on July 2015

Antibiotic resistance in Pseudomonas aeruginosa and adaptation to complex dynamic environments

scientific article published on 29 April 2020

Antibody response to Pseudomonas aeruginosa in cystic fibrosis patients: a marker of therapeutic success?--A 30-year cohort study of survival in Danish CF patients after onset of chronic P. aeruginosa lung infection

scientific article published on May 2004

Are encasings effective in asthma caused by house dust mite allergens?

scientific article published on 01 July 2003

Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole resistance.

scientific article

Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr(-/-) mice

scientific article

Azole-Resistant Aspergillus fumigatus Among Danish Cystic Fibrosis Patients: Increasing Prevalence and Dominance of TR34/L98H

scientific article published on 13 August 2020

Bacterial evolution in PCD and CF patients follows the same mutational steps

scientific article

Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment

scientific article published on 14 December 2020

Bacteriocin-mediated competition in cystic fibrosis lung infections.

scientific article published in September 2015

Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

scientific article

CT of the paranasal sinuses is not a valid indicator for sinus surgery in CF patients.

scientific article published on 20 October 2011

Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study

scientific article published on 12 July 2018

Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection

scientific article

Characterization of carbapenem nonsusceptible Pseudomonas aeruginosa in Denmark: a nationwide, prospective study

scientific article published on 21 August 2013

Clinical Relevance ofPseudomonas aeruginosa: A Master of Adaptation and Survival Strategies

Clinical care of children with primary ciliary dyskinesia

scientific article

Coexistence and within-host evolution of diversified lineages of hypermutable Pseudomonas aeruginosa in long-term cystic fibrosis infections.

scientific article

Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response.

scientific article published on 15 May 2012

Comparing whole-genome sequencing with Sanger sequencing for spa typing of methicillin-resistant Staphylococcus aureus

scientific article

Constraints on publication rights in industry-initiated clinical trials

scientific article published on 01 April 2006

Convergent Metabolic Specialization through Distinct Evolutionary Paths in Pseudomonas aeruginosa

scientific article published on 10 April 2018

Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis

scientific article published on 17 November 2014

Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis

scientific article published on 03 January 2011

Defining antimicrobial resistance in cystic fibrosis

scientific article published on 25 September 2018

Diagnostic issues, clinical characteristics, and outcomes for patients with fungemia ⬇️

scientific article

Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection

scientific article

Diversity, Prevalence, and Longitudinal Occurrence of Type II Toxin-Antitoxin Systems of Pseudomonas aeruginosa Infecting Cystic Fibrosis Lungs

scientific article published on 23 June 2017

Draft Genome Sequences of Pseudomonas aeruginosa B3 Strains Isolated from a Cystic Fibrosis Patient Undergoing Antibiotic Chemotherapy

scientific article published on 17 October 2013

Drug-Driven Phenotypic Convergence Supports Rational Treatment Strategies of Chronic Infections.

scientific article published on 26 December 2017

Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts

scientific article published on 7 April 2010

Effect of long-term voluntary exercise wheel running on susceptibility to bacterial pulmonary infections in a mouse model.

scientific article

Electrochemical sensing of biomarker for diagnostics of bacteria-specific infections

scientific article published on 27 July 2016

Emergence of extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae in Danish hospitals; this is in part explained by spread of two CTX-M-15 clones with multilocus sequence types 15 and 16 in Zealand

scientific article published on 25 May 2011

Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa

scientific article

Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain

scientific article published on 30 August 2010

Epidemic spread of Pandoraea apista, a new pathogen causing severe lung disease in cystic fibrosis patients

scientific article

Evaluation of caspofungin susceptibility testing by the new Vitek 2 AST-YS06 yeast card using a unique collection of FKS wild-type and hot spot mutant isolates, including the five most common candida species

scientific article published on 22 October 2012

Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

scientific article

Evolution of metabolic divergence in Pseudomonas aeruginosa during long-term infection facilitates a proto-cooperative interspecies interaction

scientific article published on 18 December 2015

Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone

scientific article

Evolutionary dynamics of bacteria in a human host environment

scientific article

Evolutionary highways to persistent bacterial infection

Evolutionary highways to persistent bacterial infection

scientific article published in Nature Communications

Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients

scientific article published on January 2015

Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry

scientific article published on 19 March 2016

Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis

scientific article published on 01 April 2019

Flaws in design, analysis and interpretation of Pfizer's antifungal trials of voriconazole and uncritical subsequent quotations

scientific article

Fungal infection-related mortality versus total mortality as an outcome in trials of antifungal agents

scientific article

Gene Loss and Acquisition in Lineages of Pseudomonas aeruginosa Evolving in Cystic Fibrosis Patient Airways

scientific article published on 27 October 2020

Genome analysis of a transmissible lineage of pseudomonas aeruginosa reveals pathoadaptive mutations and distinct evolutionary paths of hypermutators

scientific article (publication date: 2013)

Ghost authorship in industry-initiated randomised trials

scientific article

Has the new technology made Gram's staining method redundant? The Danish Society of Clinical Microbiology

scientific article published in March 2008

High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs

scientific article published in Nature Communications

House dust mite control measures for asthma

scientific article

Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia

scientific article published on 05 October 2018

Hypermutation as an Evolutionary Mechanism for Achromobacter xylosoxidans in Cystic Fibrosis Lung Infection

scientific article published on 21 January 2020

In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections

scientific article published on 21 December 2007

In vivo emergence of Aspergillus terreus with reduced azole susceptibility and a Cyp51a M217I alteration

scientific article published on 10 July 2012

Increasing prevalence of group B streptococcal infection among pregnant women

scientific article published on September 2014

Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa

scientific article published on 20 March 2006

Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease

scientific article

Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease

scientific article (publication date: 15 April 2009)

Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease.

scientific article

Intravenous alpha-1 antitrypsin augmentation therapy: systematic review

scientific article published on September 1, 2010

Is genotyping of single isolates sufficient for population structure analysis of Pseudomonas aeruginosa in cystic fibrosis airways?

scientific article

Is new prescription of antibiotics after treatment with sulfonamide or pivmecillinam a validated method for assessment of treatment failure?

scientific article published in February 2002

Is parotid saliva sterile on entry to the oral cavity?

journal article; published in Acta Oto-Laryngologica in 2017

Long-term social dynamics drive loss of function in pathogenic bacteria

scientific article

Loss of social behaviours in populations of Pseudomonas aeruginosa infecting lungs of patients with cystic fibrosis

scientific article published on 14 January 2014

Meropenem in cystic fibrosis patients infected with resistant Pseudomonas aeruginosa or Burkholderia cepacia and with hypersensitivity to beta-lactam antibiotics

scientific article published on January 1996

Microcontainer Delivery of Antibiotic Improves Treatment of Pseudomonas aeruginosa Biofilms

scientific article published on 22 April 2020

Misleading statements in industry-sponsored meta-analysis of itraconazole

scientific article published in December 2005

Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients

scientific article published on 29 January 2007

Molecular screening for Candida orthopsilosis and Candida metapsilosis among Danish Candida parapsilosis group blood culture isolates: proposal of a new RFLP profile for differentiation

scientific article published on 7 January 2010

Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media

scientific article

Mucosal biofilm detection in chronic otitis media: a study of middle ear biopsies from Greenlandic patients.

scientific article

Mutations causing low level antibiotic resistance ensure bacterial survival in antibiotic-treated hosts

scientific article published in Scientific Reports

Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa

scientific article published on 29 May 2012

Mycoplasma hominis meningitis in a premature baby with hydrocephalus

scientific article published in May 2005

Nanograss sensor for selective detection of Pseudomonas aeruginosa by pyocyanin identification in airway samples

scientific article published on 22 January 2020

National surveillance of fungemia in Denmark (2004 to 2009)

scientific article (publication date: 2011)

Novel Mouse Model of Chronic Pseudomonas aeruginosa Lung Infection Mimicking Cystic Fibrosis.

scientific article published in August 2005

Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis

scientific article

Nystatin prophylaxis and treatment in severely immunodepressed patients

scientific article

Omics-based tracking of Pseudomonas aeruginosa persistence in "eradicated" CF patients

scientific article published on 22 October 2020

Oropharyngeal Candidiasis in Palliative Care Patients in Denmark

scientific article

P. aeruginosa in the paranasal sinuses and transplanted lungs have similar adaptive mutations as isolates from chronically infected CF lungs

scientific article

Paper-based sensors for rapid detection of virulence factor produced by Pseudomonas aeruginosa

scientific article published on 22 March 2018

PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients

scientific article published on 3 October 2011

PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients

scientific article published on 21 November 2011

Polymyxin resistance of Pseudomonas aeruginosa phoQ mutants is dependent on additional two-component regulatory systems

scientific article published on 4 March 2013

Prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia: the value of screening with echocardiography

scientific article

Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs

scientific article published on 16 January 2020

Privatisation rescues function following loss of cooperation

Privatisation rescues function following loss of cooperation

Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients

scientific article published on 5 October 2010

Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis

scientific article published on 19 November 2020

Pseudomonas aeruginosa adaptation to lungs of cystic fibrosis patients leads to lowered resistance to phage and protist enemies

scientific article

Reconciling Antimicrobial Susceptibility Testing and Clinical Response in Antimicrobial Treatment of Chronic Cystic Fibrosis Lung Infections

scientific article published in October 2019

Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?

scientific article published on 2 May 2017

Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice.

scientific article published in December 2009

Routine versus selective antifungal administration for control of fungal infections in patients with cancer

scientific article

SERS detection of the biomarker hydrogen cyanide from Pseudomonas aeruginosa cultures isolated from cystic fibrosis patients

scientific article published on 28 March 2017

SERS spectroscopy for detection of hydrogen cyanide in breath from children colonised with P. aeruginosa

Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization

scientific article published on 20 July 2012

Short-term low-dose corticosteroids vs placebo and nonsteroidal antiinflammatory drugs in rheumatoid arthritis

scientific article

Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia

scientific article published on 5 November 2014

Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?

scientific article published on 9 October 2014

Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia

scientific article

Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients

scientific article published on 20 March 2008

Stepwise development of a homozygous S80P substitution in Fks1p, conferring echinocandin resistance in Candida tropicalis.

scientific article published on 22 October 2012

Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate

scientific article published on 14 October 2019

The Effect of Sinus Surgery with Intensive follow-up on Pathogenic Sinus Bacteria in Patients with Cystic Fibrosis

scientific article published in January 2013

The Small RNA ErsA of Pseudomonas aeruginosa Contributes to Biofilm Development and Motility through Post-transcriptional Modulation of AmrZ.

scientific article published on 15 February 2018

The clinical impact of bacterial biofilms

scientific article

The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection -- a pilot study

scientific article published on 23 October 2014

The high persister phenotype of Pseudomonas aeruginosa is associated with increased fitness and persistence in cystic fibrosis airways

scholarly article published 27 February 2019

Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes

scientific article

Towards quantitative SERS detection of hydrogen cyanide at ppb level for human breath analysis

Treatment of candidemia in a nationwide setting: increased survival with primary echinocandin treatment

scientific article published on 23 November 2018

Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients

scientific article published on 2 June 2010

Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis

scientific article

Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis

scientific article (publication date: 17 June 2013)

Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis

scientific article (publication date: 8 October 2008)

Voriconazole versus amphotericin B in cancer patients with neutropenia

scientific article

Voriconazole versus amphotericin B or fluconazole in cancer patients with neutropenia

scientific article

Whole-genome sequencing of bloodstream Staphylococcus aureus isolates does not distinguish bacteraemia from endocarditis

scientific article published in November 2017

Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients

scientific article published on 19 October 2015

[Acute infections of the hand]

scientific article published on 01 March 2009

[Constraints on publication rights in industry-initiated clinical trials--secondary publication]

scientific article published on 01 June 2006

[Epiglottitis with an abscess caused by Haemophilus parainfluenzae] ⬇️

scientific article published on 01 March 2014

[Foreign body infections--biofilms and quorum sensing]

scientific article published on 01 November 2007

[Ginseng modulates the immune response via its effect on cytokine production--secondary publication]

scientific article published on 01 August 2005

[Microbial biofilm in rhinosinusitis and cystic fibrosis]

scientific article published on 7 February 2011

[The 2nd white coat revolution?].

scientific article

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