List of works by George Kirov

5-HT2A receptor and bipolar affective disorder: association studies in affected patients

scientific article

A comprehensive family-based replication study of schizophrenia genes

scientific article

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A cross-sectional and a prospective study of thyroid disorders in lithium-treated patients.

scientific article published in August 2005

A family-based study of common polygenic variation and risk of schizophrenia

scientific article published on 12 April 2011

A genome-wide association study in 574 schizophrenia trios using DNA pooling

scientific journal article

A genome-wide study shows a limited contribution of rare copy number variants to Alzheimer's disease risk

scientific article published on 11 November 2012

A network of dopaminergic gene variations implicated as risk factors for schizophrenia

scientific article

A new form of familial multi-nodular goitre with progression to differentiated thyroid cancer.

scientific article published in June 2006

Absence of de novo point mutations in exons of GRIN2B in a large schizophrenia trio sample

Add-on topiramate reduces weight in overweight patients with affective disorders: a clinical case series

scientific article

Age-at-onset in bipolar-I disorder: mixture analysis of 1369 cases identifies three distinct clinical sub-groups

scientific article published on 4 December 2008

An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis

scientific article

An international collaborative family-based whole-genome linkage scan for high-grade myopia

scientific article published on 25 March 2009

Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2.

scientific article

Analysis of Intellectual Disability Copy Number Variants for Association With Schizophrenia

scientific article published on September 2016

Analysis of ProDH, COMT and ZDHHC8 risk variants does not support individual or interactive effects on schizophrenia susceptibility.

scientific article published on 21 July 2006

Analysis of a structural polymorphism in the 5-HT2A receptor and clinical response to clozapine

article

Analysis of copy number variations at 15 schizophrenia-associated loci.

scientific article published on 05 December 2013

Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia.

scientific article published on 21 July 2015

Analysis of neurogranin (NRGN) in schizophrenia

article published in 2011

Apolipoprotein E: depressive illness, depressive symptoms, and Alzheimer's disease.

scientific article published in February 1998

Association analysis between dopamine receptor genes and bipolar affective disorder

article

Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls

scientific article

Association between PRODH and schizophrenia is not confirmed

scientific article published in July 2003

Association of Per1 and Npas2 with autistic disorder: support for the clock genes/social timing hypothesis

scientific article published on 30 January 2007

Association of copy number variation across the genome with neuropsychiatric traits in the general population

scientific article published on 24 April 2018

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

Association study in the 5q31-32 linkage region for schizophrenia using pooled DNA genotyping

scientific article

Association study of myo-inositol monophosphatase 2 (IMPA2) polymorphisms with bipolar affective disorder and response to lithium treatment

scientific article published in January 2005

Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1).

scientific article published in April 2005

Bipolar disorder and the serotonin transporter gene: a family-based association study

article

CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1

scientific article

CNVs in neuropsychiatric disorders

scientific article

Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.

scientific article published on 16 January 2009

Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population

scientific article (publication date: September 2009)

Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools

scientific article published on 01 November 2000

Chromosome 22q11 deletions, velo-cardio-facial syndrome and early-onset psychosis

article

Clinical indicators of treatment-resistant psychosis

scientific article published on 03 June 2019

Cognitive Performance Among Carriers of Pathogenic Copy Number Variants: Analysis of 152,000 UK Biobank Subjects

scientific article

Cognitive performance and functional outcomes of carriers of pathogenic copy number variants: analysis of the UK Biobank.

scientific article

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

scientific article

Common alleles contribute to schizophrenia in CNV carriers.

scientific article published on 22 September 2015

Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia

scientific article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Contribution of de novo and inherited rare CNVs to very preterm birth

scientific article published on 12 February 2020

Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia

scientific article

Convergent patterns of association between phenylalanine hydroxylase variants and schizophrenia in four independent samples

scientific article

Copy number variation in bipolar disorder

scientific article published on 06 January 2015

Copy number variation in schizophrenia in Sweden

scientific article

Copy number variation in schizophrenia in the Japanese population

scientific article

Creativity and mental disorder

scientific article published in April 2012

DISC1 exon 11 rare variants found more commonly in schizoaffective spectrum cases than controls

scientific article published on 28 March 2011

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.

scientific article

De novo CNVs in bipolar affective disorder and schizophrenia

scientific article

De novo mutation in schizophrenia

scientific article published on 26 March 2012

De novo mutations in schizophrenia implicate synaptic networks

scientific article

De novo rates and selection of schizophrenia-associated copy number variants

scientific article published on 19 August 2011

Direct analysis of the genes encoding G proteins G alpha T2, G alpha o, G alpha Z in ADHD.

scientific article published in May 2004

Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth

scientific article

Do obstetric complications cause the earlier age at onset in male than female schizophrenics?

scientific article published in May 1996

Dopamine transporter gene (DAT1) VNTR polymorphism in major psychiatric disorders: family-based association study in the Bulgarian population

scientific article published in May 2002

Effects of genomic copy number variants penetrant for schizophrenia on cortical thickness and surface area in healthy individuals: analysis of the UK Biobank

scientific article published on 14 August 2020

Effects of pathogenic CNVs on physical traits in participants of the UK Biobank

scientific article published on 04 December 2018

Erratum: Stage 2 of the Wellcome Trust UK–Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16–q21, 4q12–q21, 9p21, 10p14–p12 and 18q22

article

Erratum: Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype

article

Ethnic differences in the presentation of bipolar affective disorder

scientific article published in July 1999

Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples

scientific article

Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha.

scientific article published on 29 September 2009

Evidence that a DISC1 frame-shift deletion associated with psychosis in a single family may not be a pathogenic mutation

scientific article published in September 2006

Evidence that duplications of 22q11.2 protect against schizophrenia

scientific article

Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia

scientific article

Family aggregation of high myopia: estimation of the sibling recurrence risk ratio.

scientific article published in September 2004

Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor

scientific article

Finding schizophrenia genes

scientific article

Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder

scientific article published on 06 April 2010

Fine-mapping reveals novel alternative splicing of the dopamine transporter

scientific article

Four years of successful maintenance electroconvulsive therapy

scientific article published in September 2009

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

scientific article

Gender differences in CNV burden do not confound schizophrenia CNV associations.

scientific article published on 17 May 2016

Genetic association of FMRP targets with psychiatric disorders

scientific article published on 19 October 2020

Genetic differences between five European populations

scientific article published on 08 July 2010

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept

scientific article

Genetic variation in the seven-pass transmembrane cadherin CELSR1: lack of association with schizophrenia

scientific article

Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK.

scientific article published in January 2006

Genetics of epilepsy: epilepsy research foundation workshop report

scientific article published in June 2007

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

scientific article

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

scientific article published on 20 June 2017

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genome-wide association study on bipolar disorder in the Bulgarian population

scientific journal article

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

scientific article published on 11 December 2015

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

scientific article published on 9 August 2016

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.

scientific article published on 12 July 2016

Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms.

scientific article

Genome-wide pooling approach identifies SPATA5 as a new susceptibility locus for alopecia areata

scientific article published on 26 October 2011

Genomewide Linkage Scan in Schizoaffective Disorder

scientific article published on 01 October 2005

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

scientific article published on 8 August 2017

IGF1, growth pathway polymorphisms and schizophrenia: A pooling study

scientific article published on 01 January 2007

Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).

scientific article

Identification of a potential bipolar risk haplotype in the gene encoding the winged-helix transcription factor RFX4.

scientific article

Identification of loci associated with schizophrenia by genome-wide association and follow-up

scientific article

Impact of schizophrenia genetic liability on the association between schizophrenia and physical illness: data-linkage study

scientific article published on 10 November 2020

Implication of a rare deletion at distal 16p11.2 in schizophrenia

scientific article published on March 2013

Independent estimation of the frequency of rare CNVs in the UK population confirms their role in schizophrenia

scientific article published on 29 November 2011

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia

scientific article

International Consortium on the Genetics of Electroconvulsive Therapy and Severe Depressive Disorders (Gen-ECT-ic)

scientific article published on 04 December 2019

Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin

scientific article published in August 2004

Linkage Analysis of the Genetic Loci for High Myopia on 18p, 12q, and 17q in 51 U.K. Families

article

Linkage disequilibrium mapping of bipolar affective disorder at 12q23-q24 provides evidence for association at CUX2 and FLJ32356

scientific article

Linkage studies in bipolar affective disorder with markers on chromosome 21

scientific article published on 01 December 1996

Localization of bipolar susceptibility locus by molecular genetic analysis of the chromosome 12q23-q24 region in two pedigrees with bipolar disorder and Darier's disease

scientific article published in January 2005

Major psychiatric disorders and the serotonin transporter gene (SLC6A4): family-based association studies

scientific article published in September 2002

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

scientific article published on 8 April 2022

Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness

scientific article

Medical and neurobehavioural phenotypes in carriers of X-linked ichthyosis-associated genetic deletions in the UK Biobank

scientific article published on 05 March 2020

Medical consequences of pathogenic CNVs in adults: analysis of the UK Biobank

scientific article published on 20 October 2018

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

scientific article

Meta-analysis of studies on genetic variation in 5-HT2A receptors and clozapine response.

scientific article published in July 1998

Microduplications of 16p11.2 are associated with schizophrenia

scientific article

Mood-incongruent psychosis in bipolar disorder: conditional linkage analysis shows genome-wide suggestive linkage at 1q32.3, 7p13 and 20q13.31

article

Mosaic copy number variation in schizophrenia

scientific article

Mutation screening and LD mapping in the VCFS deleted region of chromosome 22q11 in schizophrenia using a novel DNA pooling approach.

scientific article published in January 2002

Mutation screening of SCN2A in schizophrenia and identification of a novel loss-of-function mutation

scientific article published on 9 November 2015

Mutation screening of the 3q29 microdeletion syndrome candidate genes DLG1 and PAK2 in schizophrenia

scientific article published on 17 August 2011

Neurexin 1 (NRXN1) deletions in schizophrenia

scientific article

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

scientific article

No association between schizophrenia and polymorphisms in COMT in two large samples

scientific article published in September 2005

No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples

scientific article

No evidence for an association of affective disorders with high- or low-activity allele of catechol-o-methyltransferase gene

article

Non-random mating, parent-of-origin, and maternal-fetal incompatibility effects in schizophrenia

scientific article

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia

scientific article

Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder

scientific article published in June 2005

P2RX7: A bipolar and unipolar disorder candidate susceptibility gene?

scientific article published in December 2009

Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders.

scientific article

Pathogenic copy number variants and SCN1A mutations in patients with intellectual disability and childhood-onset epilepsy

scientific article

Phenotypic variations on the theme of CNVs

Plasma magnesium levels in a population of psychiatric patients: correlations with symptoms.

scientific article published in January 1994

Polygenic dissection of the bipolar phenotype

scientific article

Pooled DNA genotyping on Affymetrix SNP genotyping arrays

scientific article

Population structure and genome-wide patterns of variation in Ireland and Britain

scientific article

Positional cloning, association analysis and expression studies provide convergent evidence that the cadherin gene FAT contains a bipolar disorder susceptibility allele.

scientific article

Quick recovery of orientation after magnetic seizure therapy for major depressive disorder

scientific article published on August 2008

Rare chromosomal deletions and duplications increase risk of schizophrenia

scientific article

Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia

scientific article published on April 2010

Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures

scientific article published on 7 February 2013

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.

scientific article

Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia

scientific article published on 17 July 2013

Reduced burden of very large and rare CNVs in bipolar affective disorder

scientific article published on 16 October 2013

Relative suppression of magical thinking: a transcranial magnetic stimulation study

scientific article

Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample

scientific article published on 16 October 2012

SGCE and myoclonus dystonia: motor characteristics, diagnostic criteria and clinical predictors of genotype.

scientific article published on 11 September 2014

SGCE mutations cause psychiatric disorders: clinical and genetic characterization

scientific article

Schizophrenia and functional polymorphisms in the MAOA and COMT genes: no evidence for association or epistasis.

scientific article published in July 2002

Schizophrenia copy number variants and associative learning

scientific article published on 13 December 2016

Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain

scientific article published on 22 February 2011

Schizophrenia two-hit hypothesis in velo-cardio facial syndrome

scientific article published on 17 January 2013

Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder.

scientific article

Screening the human protocadherin 8 (PCDH8) gene in schizophrenia.

scientific article

Sequence analysis of 17 NRXN1 deletions.

scientific article published on 25 September 2013

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

scientific article

Stage 2 of the Wellcome Trust UK-Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16-q21, 4q12-q21, 9p21, 10p14-p12 and 18q22.

scientific article published on September 2005

Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria

scientific article

Strong evidence that GNB1L is associated with schizophrenia

scientific article

Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype

scientific article

Support for RGS4 as a susceptibility gene for schizophrenia

scientific article

Support for neuregulin 1 as a susceptibility gene for bipolar disorder and schizophrenia

scientific article published on 7 May 2008

Support for the involvement of large copy number variants in the pathogenesis of schizophrenia

scientific article published on 29 January 2009

The Bipolar Affective Disorder Dimension Scale (BADDS)--a dimensional scale for rating lifetime psychopathology in bipolar spectrum disorders

scientific article

The Effectiveness of Electroconvulsive Therapy in Treatment-Resistant Depression

article

The Wellcome trust UK–Irish bipolar affective disorder sibling-pair genome screen: first stage report

article by P Bennett et al published February 2002 in Molecular Psychiatry

The antidepressant debate should move on

The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia

scientific article

The effects of etomidate on seizure duration and electrical stimulus dose in seizure-resistant patients during electroconvulsive therapy

scientific article published in September 2006

The molecular genetics of schizophrenia: progress so far.

scientific article published on March 1997

The penetrance of copy number variations for schizophrenia and developmental delay.

scientific article

Thyroid disorders in lithium-treated patients

scientific article published in July 1998

Tryptophan Hydroxylase Gene and Manic-Depressive Illness

article

Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools.

scientific article published on 23 March 2002

Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder

scientific article published in April 2006

Variation in the protocadherin gamma A gene cluster.

scientific article published in October 2003

Whole genome association study in a homogenous population in Shandong peninsula of China reveals JARID2 as a susceptibility gene for schizophrenia

scientific article published on 27 October 2009

Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene

scientific journal article

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