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List of works by Corey Nislow

"Chemogenomics: tools for protein families" and "Chemical genomics: chemical and biological integration".

scientific article

14-3-3ζ coordinates adipogenesis of visceral fat.

scientific article published on 29 July 2015

17 Chemical Genomic Tools for Understanding Gene Function and Drug Action

article

A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction

scientific article

A comparative analysis of DNA barcode microarray feature size

scientific article

A compendium of nucleosome and transcript profiles reveals determinants of chromatin architecture and transcription

scientific article

A competence-regulated toxin-antitoxin system in Haemophilus influenzae

scientific article published on 13 January 2020

A comprehensive platform for highly multiplexed mammalian functional genetic screens

scientific article

A genome scale overexpression screen to reveal drug activity in human cells

scientific article

A high-resolution atlas of nucleosome occupancy in yeast

scientific article

A high-throughput yeast assay identifies synergistic drug combinations

scientific article published on June 2013

A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters

scientific article

A novel calcineurin-independent activity of cyclosporin A in Saccharomyces cerevisiae

scientific article published on 01 October 2012

A novel small molecule methyltransferase is important for virulence in Candida albicans

scientific article published on 16 October 2013

A phenotypic screening platform to identify small molecule modulators of Chlamydomonas reinhardtii growth, motility and photosynthesis.

scientific article

A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles

scientific article

A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans

scientific article published on 30 May 2010

A survey of yeast genomic assays for drug and target discovery

scientific article published on 28 May 2010

A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis

scientific article

A unified model for yeast transcript definition

scientific article published on 29 October 2013

A unique and universal molecular barcode array

scientific article

Absence of Activation of DNA Repair Genes and Excellent Efficacy of Phosphaplatins against Human Ovarian Cancers: Implications To Treat Resistant Cancers

scientific article published on 12 October 2015

Accelerating the discovery of biologically active small molecules using a high-throughput yeast halo assay

scientific article published on 10 February 2007

Alternative splicing of PTC7 in Saccharomyces cerevisiae determines protein localization

scientific article

An algorithm for chemical genomic profiling that minimizes batch effects: bucket evaluations

scientific article

An integrated platform of genomic assays reveals small-molecule bioactivities

scientific article

Barcode Sequencing for Understanding Drug–Gene Interactions

article

Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance

scientific article published on 08 February 2022

Biological and therapeutic implications of a unique subtype of NPM1 mutated AML

scientific article published on 16 February 2021

Broad metabolic sensitivity profiling of a prototrophic yeast deletion collection

scientific article

Bugs, drugs and chemical genomics

scientific article published on 15 December 2011

CHIP-MYTH: a novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β₂-adrenergic receptor

scientific article published on 19 February 2014

Caenorhabditis elegans is a useful model for anthelmintic discovery.

scientific article published on 25 June 2015

Chemical genomic profiling for identifying intracellular targets of toxicants producing Parkinson's disease

scientific article published on 16 October 2006

Chemical-genetic approaches for exploring the mode of action of natural products

Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells

scientific article

Chemogenomic Profiling

Chemogenomic approaches to elucidation of gene function and genetic pathways

scientific article published on January 2009

Chromatin is an ancient innovation conserved between Archaea and Eukarya

scientific article

Chromosome-wide histone deacetylation by sirtuins prevents hyperactivation of DNA damage-induced signaling upon replicative stress

scientific article published on 8 January 2016

Combination chemical genetics

scientific article

Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis

scientific article published on 14 January 2009

Comparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agents

scientific article

Comparative functional genomic screens of three yeast deletion collections reveal unexpected effects of genotype in response to diverse stress

scientific article

Competitive genomic screens of barcoded yeast libraries

scientific article

Compound prioritization methods increase rates of chemical probe discovery in model organisms

scientific article

Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis

scientific article

Conserved substitution patterns around nucleosome footprints in eukaryotes and Archaea derive from frequent nucleosome repositioning through evolution

scientific article

Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation

scientific article published on 9 September 2011

DNA-damaging agents in cancer chemotherapy: serendipity and chemical biology

scientific article published on May 2013

Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans

scientific article published on 6 November 2011

Design, synthesis and characterization of a highly effective inhibitor for analog-sensitive (as) kinases

scientific article

Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast

scientific article

Discovery of novel small molecule modulators of Clavibacter michiganensis subsp. michiganensis

scientific article published on 19 October 2015

Displaying chemical information on a biological network using Cytoscape

scientific article published on January 2011

Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

scientific article

Diversity of eukaryotic DNA replication origins revealed by genome-wide analysis of chromatin structure

scientific article

Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell.

scientific article

Dual action antifungal small molecule modulates multidrug efflux and TOR signaling

scientific article

Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation

scientific article

Endophytic colonization of barley (Hordeum vulgare) roots by the nematophagous fungus Pochonia chlamydosporia reveals plant growth promotion and a general defense and stress transcriptomic response

scientific article published on 17 May 2015

Endosomal protein sorting and autophagy genes contribute to the regulation of yeast life span.

scientific article published on 16 November 2010

Erratum: Corrigendum: An integrated platform of genomic assays reveals small-molecule bioactivities

article

Erratum: Corrigendum: Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans

scholarly article published in Nature Chemical Biology

Experimental approaches to identify genetic networks

scientific article published on 8 September 2006

Exploring Gene Function and Drug Action Using Chemogenomic Dosage Assays

article

Faculty of 1000 evaluation for A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

Faculty of 1000 evaluation for Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution

Faculty of 1000 evaluation for Decoupling Epigenetic and Genetic Effects through Systematic Analysis of Gene Position

article

Faculty of 1000 evaluation for One-step purification of assembly competent tubulin from diverse eukaryotic sources

Faculty of 1000 evaluation for Parallel mapping and simultaneous sequencing reveals deletions in BCAN and FAM83H associated with discrete inherited disorders in a domestic dog breed

Faculty of 1000 evaluation for Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform

article published in 2012

GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris

scientific article

Gene annotation and drug target discovery in Candida albicans with a tagged transposon mutant collection

scientific article

Genes required for survival in microgravity revealed by genome-wide yeast deletion collections cultured during spaceflight

scientific article published on 13 January 2015

Genetic and genomic architecture of the evolution of resistance to antifungal drug combinations

scientific article

Genome sequence of Shigella flexneri serotype 5a strain M90T Sm

scientific article

Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death.

scientific article

Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures.

scientific article published in January 2007

Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pH(c) in Saccharomyces cerevisiae

scientific article published on 10 September 2012

Genome-wide requirements for resistance to functionally distinct DNA-damaging agents

scientific article

Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation

scientific article

Genomic approaches for determining nucleosome occupancy in yeast

scientific article

Genotype to phenotype: a complex problem

Scientific article

Global Analysis of the Fungal Microbiome in Cystic Fibrosis Patients Reveals Loss of Function of the Transcriptional Repressor Nrg1 as a Mechanism of Pathogen Adaptation

scientific article (publication date: November 2015)

Idebenone and coenzyme Q10are novel PPARα/γ ligands, with potential for treatment of fatty liver diseases

scientific article published on 31 August 2018

Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids

scientific article published on 23 June 2015

Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen

scientific article

Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics

scientific article

Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia

scientific article published on November 2011

Insight into the Recent Genome Duplication of the Halophilic Yeast Hortaea werneckii: Combining an Improved Genome with Gene Expression and Chromatin Structure

scientific article

Interactively AUDIT Your Growth Curves with a Suite of R Packages

scientific article published on 05 March 2020

Introns regulate RNA and protein abundance in yeast

scientific article (publication date: September 2006)

Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection

scientific article

Knocking sense into regulatory pathways

scientific article published in February 2009

List of Contributors

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors

scientific article

Microbial and biochemical basis of a Fusarium wilt-suppressive soil

scientific article

Microtubule Dynamics and Chromosome Movement

article

Mitochondrial electron transport is the cellular target of the oncology drug elesclomol

scientific article

Molecular components of the mitotic spindle

scientific article

Most "dark matter" transcripts are associated with known genes

scientific article published in May 2010

Multiple means to the same end: the genetic basis of acquired stress resistance in yeast

scientific article

New azole antifungal agents with novel modes of action: synthesis and biological studies of new tridentate ligands based on pyrazole and triazole

scientific article

Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae

scientific article

Nucleosome-coupled expression differences in closely-related species

scientific article

Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast

scientific article

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

scientific article published on 14 September 2016

PITPs as targets for selectively interfering with phosphoinositide signaling in cells

scientific article

Pharmacogenomics at the Point of Care: A Community Pharmacy Project in British Columbia

scientific article published on 24 December 2020

Phenotypic diversity and genotypic flexibility of Burkholderia cenocepacia during long-term chronic infection of cystic fibrosis lungs

scientific article published on 21 March 2017

Precise gene-dose alleles for chemical genetics

scientific article published on 30 March 2009

Quantitative phenotyping via deep barcode sequencing.

scientific article

Recent advances and method development for drug target identification

scientific article published on 07 December 2009

Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system

scientific article

Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation

scientific article

Regionalized Cell Division during Sea Urchin Gastrulation Contributes to Archenteron Formation and Is Correlated with the Establishment of Larval Symmetry. (sea urchin/gastrulation/cell division/autoradiography)

Response to “The Reality of Pervasive Transcription”

scientific article

Reverse Chemical Genetics: Comprehensive Fitness Profiling Reveals the Spectrum of Drug Target Interactions

scientific article

SET1, a yeast member of the trithorax family, functions in transcriptional silencing and diverse cellular processes

scientific article

Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells

scientific article published on July 2015

Self-reporting cells

scientific article published on April 2009

Sequencing and functional analysis of the genome of a nematode egg-parasitic fungus, Pochonia chlamydosporia.

scientific article published on 13 February 2014

Serum MicroRNAs Reflect Injury Severity in a Large Animal Model of Thoracic Spinal Cord Injury

scientific article

Signature-tagged mutagenesis to characterize genes through competitive selection of bar-coded genome libraries

scientific article

Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action

scientific article

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

scientific article published on 27 March 2011

Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions

scientific article published on 07 January 2007

The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4.

scientific article published on 19 April 2011

The automated cell: compound and environment screening system (ACCESS) for chemogenomic screening

scientific article published in January 2011

The genetic landscape of a cell

scientific article

The origin of skeleton forming cells in the sea urchin embryo

scientific article published in January 1988

The synthetic genetic interaction network reveals small molecules that target specific pathways in Sacchromyces cerevisiae

scientific article

The yeast deletion collection: a decade of functional genomics

scientific article

Timing of transcriptional quiescence during gametogenesis is controlled by global histone H3K4 demethylation

scientific article

Transcriptome analysis of Campylobacter jejuni polyphosphate kinase (ppk1 and ppk2) mutants

scientific article published on 5 November 2015

Two-color cell array screen reveals interdependent roles for histone chaperones and a chromatin boundary regulator in histone gene repression

scientific article

Using C. elegans Forward and Reverse Genetics to Identify New Compounds with Anthelmintic Activity

scientific article

Whole genome duplication and enrichment of metal cation transporters revealed by de novo genome sequencing of extremely halotolerant black yeast Hortaea werneckii

scientific article published in 2013

Yeast Barcoders: a chemogenomic application of a universal donor-strain collection carrying bar-code identifiers

scientific article published on 11 July 2008

Yeast chemical genomics and drug discovery: an update

scientific article published on 26 August 2008

You too can play with an edge

scientific article published in November 2009

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