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List of works by Nenad Sestan

A MARKOV RANDOM FIELD-BASED APPROACH TO CHARACTERIZING HUMAN BRAIN DEVELOPMENT USING SPATIAL-TEMPORAL TRANSCRIPTOME DATA. ⬇️

scientific article

A Markov random field-based approach for joint estimation of differentially expressed genes in mouse transcriptome data

scientific article

A multiregional proteomic survey of the postnatal human brain.

scientific article published on 13 November 2017

An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder

scientific article published on 26 April 2018

Axonal ribosomes and mRNAs associate with fragile X granules in adult rodent and human brains.

scientific article published on 12 January 2017

Cis-regulatory control of corticospinal system development and evolution ⬇️

scientific article published on May 30, 2012

Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism

scientific article

Comprehensive cellular-resolution atlas of the adult human brain

scientific article published on 15 July 2016

Comprehensive cellular-resolution atlas of the adult human brain

Comprehensive cellular-resolution atlas of the adult human brain.

scientific article published in February 2017

Comprehensive functional genomic resource and integrative model for the human brain

scientific article published on 01 December 2018

Control of species-dependent cortico-motoneuronal connections underlying manual dexterity.

scientific article published in July 2017

Cortical projection neurons: sprung from the same root

scientific article

Coupling diffusion imaging with histological and gene expression analysis to examine the dynamics of cortical areas across the fetal period of human brain development.

scientific article published on 28 August 2012

Cux2 expression regulated by Lhx2 in the upper layer neurons of the developing cortex

scientific article published on 08 November 2019

DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics

scientific article

Developmentally regulated and evolutionarily conserved expression of SLITRK1 in brain circuits implicated in Tourette syndrome

scientific article

Different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis.

scientific article published on 7 December 2017

Differential Gene Expression in the Human Brain Is Associated with Conserved, but Not Accelerated, Noncoding Sequences

scientific article

Disruption of NEUROD2 causes a neurodevelopmental syndrome with autistic features via cell-autonomous defects in forebrain glutamatergic neurons

scientific article published on 29 June 2021

Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly

scientific article published on 08 March 2017

Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination

scientific article published on 24 February 2016

Dynamic and Cell-Specific DACH1 Expression in Human Neocortical and Striatal Development.

scientific article published on 24 April 2018

Early emergence of cortical interneuron diversity in the mouse embryo.

scientific article published on 22 February 2018

Evolution of Osteocrin as an activity-regulated factor in the primate brain

scientific journal article

Evolution of the Human Nervous System Function, Structure, and Development

scientific article published in July 2017

Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus

scientific article published on 19 October 2020

From trans to cis: transcriptional regulatory networks in neocortical development

scientific article

Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development

scientific article

Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder

scientific article published on 01 December 2018

Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes

scientific article published on 20 March 2020

Hominini-specific regulation of CBLN2 increases prefrontal spinogenesis

scientific article published on 01 October 2021

Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit

scientific article published in Nature Communications

Integrative functional genomic analysis of human brain development and neuropsychiatric risks

scientific article published on 01 December 2018

Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex.

scientific article

Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network

scientific article

Isoform-Level Interpretation of High-Throughput Proteomics Data Enabled by Deep Integration with RNA-seq

article

Laminar and columnar development of barrel cortex relies on thalamocortical neurotransmission

scientific article published on September 2013

Laminar and temporal expression dynamics of coding and noncoding RNAs in the mouse neocortex

scientific article published on 20 February 2014

Lost in Translation: Traversing the Complex Path from Genomics to Therapeutics in Autism Spectrum Disorder

scientific article published on 01 October 2018

Microarray analysis of microRNA expression in the developing mammalian brain

scientific article published in 2004

Midline radial glia translocation and corpus callosum formation require FGF signaling

scientific article published on 21 May 2006

Modeling the Evolution of Human Brain Development Using Organoids

scientific article published on 01 November 2019

Molecular and cellular reorganization of neural circuits in the human lineage.

scientific article published in November 2017

Molecular programs of regional specification and neural stem cell fate progression in macaque telencephalon

scientific article published on 12 October 2023

Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities

scientific article

Neocortical networks entrain neuronal circuits in cerebellar cortex

scientific article

Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold

scientific article published on 22 July 2020

Neuregulin 1-erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex

scientific journal article

Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus

scholarly article

Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors

scientific journal article

Population-averaged macaque brain atlas with high-resolution ex vivo DTI integrated into in vivo space

scientific article published on 20 June 2017

Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins

scientific article published on 9 August 2017

Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche

scientific journal article

Prolonged myelination in human neocortical evolution

scientific article

Rare deleterious mutations of the gene EFR3A in autism spectrum disorders.

scientific article

Recessive LAMC3 mutations cause malformations of occipital cortical development

scientific article published on 15 May 2011

Reciprocal Connections Between Cortex and Thalamus Contribute to Retinal Axon Targeting to Dorsal Lateral Geniculate Nucleus

scientific article published on 10 March 2017

Regulation of prefrontal patterning and connectivity by retinoic acid

scientific article published on 01 October 2021

Restoration of brain circulation and cellular functions hours post-mortem

scientific article published on 17 April 2019

SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons

scholarly article

Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex

scientific journal article

Selective depletion of molecularly defined cortical interneurons in human holoprosencephaly with severe striatal hypoplasia

scientific article published on 20 February 2009

Sequence variants in SLITRK1 are associated with Tourette's syndrome

scientific article

Shared and derived features of cellular diversity in the human cerebral cortex

scientific article published on 21 January 2019

Simultaneous dimension reduction and adjustment for confounding variation

scientific article published on 07 December 2016

Spatial and cell type transcriptional landscape of human cerebellar development

scientific article published on 17 June 2021

Spatial and single-cell transcriptional landscape of human cerebellar development ⬇️

journal article from 'bioRxiv' published in 2020

Spatial mapping of structural and connectional imaging data for the developing human brain with diffusion tensor imaging

scientific article

Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production.

scientific article

Spatio-temporal transcriptome of the human brain

scientific article (publication date: 26 October 2011)

Spatiotemporal transcriptomic divergence across human and macaque brain development

scientific article

Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex.

scientific article published on May 2012

TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract

scientific article

TSHZ3 deletion causes an autism syndrome and defects in cortical projection neurons

scientific article

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms

scientific article

Temporal specification and bilaterality of human neocortical topographic gene expression

scientific article

The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development

article

The BRAIN Initiative Cell Census Consortium: Lessons Learned toward Generating a Comprehensive Brain Cell Atlas

scientific article published on November 2017

The CeNGEN Project: The Complete Gene Expression Map of an Entire Nervous System.

scientific article

The Cellular and Molecular Landscapes of the Developing Human Central Nervous System

scientific article published on January 2016

The PsychENCODE project

scientific article

The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders

article by A Jeremy Willsey et al published 26 July 2018 in Cell

The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment

scientific article

The developmental transcriptome of the human brain: implications for neurodevelopmental disorders

scientific article

The ethics of experimenting with human brain tissue

scientific article published in Nature

The evolution of the human brain and disease susceptibility

scientific article published on 03 July 2020

The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling

scientific article

The long noncoding RNA may regulate expression of several schizophrenia-related genes

article

The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity

scientific article published on 12 April 2007

Transcriptional co-regulation of neuronal migration and laminar identity in the neocortex ⬇️

scientific article published on May 1, 2012

Transcriptional landscape of the prenatal human brain

scientific article

Transcriptional priming as a conserved mechanism of lineage diversification in the developing mouse and human neocortex

scientific article published on 06 November 2020

Transcriptome Analysis of the Human Striatum in Tourette Syndrome

scientific article

Transcriptome and epigenome landscape of human cortical development modeled in organoids

scientific article

Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates

scientific article published on 01 May 2020

Whole-Genome and RNA Sequencing Reveal Variation and Transcriptomic Coordination in the Developing Human Prefrontal Cortex

scientific article published on 01 April 2020

Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations

scientific article

XSAnno: a framework for building ortholog models in cross-species transcriptome comparisons

scientific article

Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex

scientific journal article

Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia

scientific article

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