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List of works by Mariano Esteban

A 14,000-Mr envelope protein of vaccinia virus is involved in cell fusion and forms covalently linked trimers

scientific article published on February 1987

A 14K envelope protein of vaccinia virus with an important role in virus-host cell interactions is altered during virus persistence and determines the plaque size phenotype of the virus

scientific article

A Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV Immunogen

scientific article

A Comparative Phase I Study of Combination, Homologous Subtype-C DNA, MVA, and Env gp140 Protein/Adjuvant HIV Vaccines in Two Immunization Regimes

scientific article published on 22 February 2017

A Novel MVA-Based HIV Vaccine Candidate (MVA-gp145-GPN) Co-Expressing Clade C Membrane-Bound Trimeric gp145 Env and Gag-Induced Virus-Like Particles (VLPs) Triggered Broad and Multifunctional HIV-1-Specific T Cell and Antibody Responses

article

A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART.

scientific article

A Prime/Boost PfCS14KM/MVA-sPfCSM Vaccination Protocol Generates Robust CD8+ T Cell and Antibody Responses to Plasmodium falciparum Circumsporozoite Protein and Protects Mice against Malaria

scientific article published on 15 March 2017

A Vaccine Based on a Modified Vaccinia Virus Ankara Vector Expressing Zika Virus Structural Proteins Controls Zika Virus Replication in Mice

scientific article published in Scientific Reports

A candidate HIV/AIDS vaccine (MVA-B) lacking vaccinia virus gene C6L enhances memory HIV-1-specific T-cell responses

scientific article published in 2011

A heterologous prime-boost regime using DNA and recombinant vaccinia virus expressing the Leishmania infantum P36/LACK antigen protects BALB/c mice from cutaneous leishmaniasis.

scientific article published in January 2002

A human immunodeficiency virus type 1 Env-granulocyte-macrophage colony-stimulating factor fusion protein enhances the cellular immune response to Env in a vaccinia virus-based vaccine

scientific article published on January 1999

A human multi-epitope recombinant vaccinia virus as a universal T cell vaccine candidate against influenza virus

scientific article

A mutation of the nucleoside triphosphate phosphohydrolase I (NPH-I) gene confers sensitivity of vaccinia virus to interferon.

scientific article published on November 1993

A novel HIV vaccine adjuvanted by IC31 induces robust and persistent humoral and cellular immunity

scientific article

A novel poxvirus-based vaccine, MVA-CHIKV, is highly immunogenic and protects mice against chikungunya infection.

scientific article published on 08 January 2014

A poxvirus Bcl-2-like gene family involved in regulation of host immune response: sequence similarity and evolutionary history

scientific article published on 15 March 2010

A random DNA sequencing, computer-based approach for the generation of a gene map of molluscum contagiosum virus

scientific article published on January 1997

A single point mutation of Ala-25 to Asp in the 14,000-Mr envelope protein of vaccinia virus induces a size change that leads to the small plaque size phenotype of the virus

scientific article published on November 1989

A striking property of recombinant poxviruses: efficient inducers of in vivo expansion of primed CD8(+) T cells

scientific article

A vaccinia virus core protein, p39, is membrane associated.

scientific article published in October 1996

A vaccinia virus lacking A10L: viral core proteins accumulate on structures derived from the endoplasmic reticulum.

scientific article published on March 2006

Activation of NF-kB pathway by virus infection requires Rb expression

scientific article

Activation of NF-kappa B by the dsRNA-dependent protein kinase, PKR involves the I kappa B kinase complex

scientific article published in March 2000

Activation of the IFN-Inducible Enzyme RNase L Causes Apoptosis of Animal Cells ⬇️

scientific article published on September 29, 1997

Activation of the double-stranded RNA-dependent protein kinase PKR by small ubiquitin-like modifier (SUMO).

scientific article published on 29 July 2014

Adjuvant-like effect of vaccinia virus 14K protein: a case study with malaria vaccine based on the circumsporozoite protein

scientific article

Administration to mice of a monoclonal antibody that neutralizes the intracellular mature virus form of vaccinia virus limits virus replication efficiently under prophylactic and therapeutic conditions

scientific article published in May 2002

Aerosol immunization with NYVAC and MVA vectored vaccines is safe, simple, and immunogenic

scholarly article

African swine fever virus gene A179L, a viral homologue of bcl-2, protects cells from programmed cell death

scientific article published on November 1996

Alphavirus replicon DNA expressing HIV antigens is an excellent prime for boosting with recombinant modified vaccinia Ankara (MVA) or with HIV gp140 protein antigen.

scientific article

An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses

scientific article

An MVA Vector Expressing HIV-1 Envelope under the Control of a Potent Vaccinia Virus Promoter as a Promising Strategy in HIV/AIDS Vaccine Design

scientific article published on 06 December 2019

Anti-apoptotic and oncogenic properties of the dsRNA-binding protein of vaccinia virus, E3L.

scientific article published on December 2002

Antigenicity of Leishmania-Activated C-Kinase Antigen (LACK) in Human Peripheral Blood Mononuclear Cells, and Protective Effect of Prime-Boost Vaccination With pCI-neo-LACK Plus Attenuated LACK-Expressing Vaccinia Viruses in Hamsters.

scientific article

Antiviral action of the tumor suppressor ARF

scientific article

Antiviral effect of prostaglandins of the A series: inhibition of vaccinia virus replication in cultured cells

scientific article published in December 1982

Assembly of vaccinia virus: incorporation of p14 and p32 into the membrane of the intracellular mature virus.

scientific article published in June 1995

Attenuated and replication-competent vaccinia virus strains M65 and M101 with distinct biology and immunogenicity as potential vaccine candidates against pathogens.

scientific article published on 17 April 2013

Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus

scientific article published on 23 March 2017

Attenuated modified vaccinia virus Ankara can be used as an immunizing agent under conditions of preexisting immunity to the vector

scientific article published on August 2000

Attenuated poxviruses expressing a synthetic HIV protein stimulate HLA-A2-restricted cytotoxic T-cell responses

scientific article published on 01 September 2004

Balance between activation and regulation of HIV-specific CD8+ T-cell response after modified vaccinia Ankara B therapeutic vaccination

scientific article

Bcl-2 prevents nitric oxide-mediated apoptosis and poly(ADP-ribose) polymerase cleavage

scientific article published on 01 February 1997

Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: virus fate and activation of B- and T-cell immune responses in comparison with the Western Reserve strain and advantages as a vaccine

scientific article published on January 2000

Bioluminescence Imaging as a Tool for Poxvirus Biology

scientific article published on 01 January 2019

COVID-19 vaccine candidates based on modified vaccinia virus Ankara expressing the SARS-CoV-2 spike induce robust T- and B-cell immune responses and full efficacy in mice

scientific article published on 07 January 2021

Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: molecular mechanism and relevance.

scientific article published in October 2002

Cellular and biochemical differences between two attenuated poxvirus vaccine candidates (MVA and NYVAC) and role of the C7L gene

scientific article

Cellular gene expression survey of vaccinia virus infection of human HeLa cells.

scientific article

Characterization of early stages in vaccinia virus membrane biogenesis: implications of the 21-kilodalton protein and a newly identified 15-kilodalton envelope protein.

scientific article

Characterization ofin VivoPrimary and Secondary CD8+T Cell Responses Induced by Recombinant Influenza and Vaccinia Viruses

article

Chimeras between the human immunodeficiency virus (HIV-1) Env and vaccinia virus immunogenic proteins p14 and p39 generate in mice broadly reactive antibodies and specific activation of CD8+ T cell responses to Env.

scientific article published in July 2000

Clinical applications of attenuated MVA poxvirus strain.

scientific article published on 30 October 2013

Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization

scientific article published on 6 February 2013

Comparison of Immunogenicity in Rhesus Macaques of Transmitted-Founder, HIV-1 Group M Consensus, and Trivalent Mosaic Envelope Vaccines Formulated as a DNA Prime, NYVAC, and Envelope Protein Boost

scientific article published on 8 April 2015

Comparison of Safety and Vector-Specific Immune Responses in Healthy and HIV-Infected Populations Vaccinated with MVA-B

scientific article published on 07 November 2019

Comparison of the depth of vaccine-elicited HIV-1 Env epitope-specific CD8+ T lymphocyte responses

scientific article

Conjugation of SUMO to p85 leads to a novel mechanism of PI3K regulation.

scientific article

Control of virus infection by tumour suppressors.

scientific article published on 7 March 2007

Correction for Kibler et al., "Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC"

scientific article published on 15 October 2019

Correction: F11-Mediated Inhibition of RhoA Signalling Enhances the Spread of Vaccinia Virus In Vitro and In Vivo in an Intranasal Mouse Model of Infection.

scientific article published on 8 June 2010

Correction: ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection

scientific article published on 13 October 2016

Correction: ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection.

scientific article published on 30 October 2013

Correction: Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization.

scientific article

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C

scientific article published in PLoS ONE

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C.

scientific article published on 17 May 2012

Corrigendum to "A heterologous prime-boosting strategy with replicating Vaccinia virus vectors and plant-produced HIV-1 Gag/dgp41 virus-like particles" [Virology 507 (2017) 242-256]

scientific article published on 06 June 2019

Cryo X-ray nano-tomography of vaccinia virus infected cells

scientific article

Cryo-X-ray tomography of vaccinia virus membranes and inner compartments.

scientific article published on 16 July 2009

Current situation in the development of a preventive HIV vaccine

scientific article

DNA-binding proteins in the cytoplasm of vaccinia virus-infected mouse L-cells ⬇️

scientific article published on January 1, 1978

DNA/NYVAC vaccine regimen induces HIV-specific CD4 and CD8 T-cell responses in intestinal mucosa.

scientific article

Deletion of Vaccinia Virus A40R Gene Improves the Immunogenicity of the HIV-1 Vaccine Candidate MVA-B

scientific article published on 06 February 2020

Deletion of the vaccinia virus N2L gene encoding an inhibitor of IRF3 improves the immunogenicity of modified vaccinia virus Ankara expressing HIV-1 antigens.

scientific article published on 03 January 2014

Deletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity in mice of the HIV/AIDS vaccine candidate NYVAC-C

scientific article (publication date: 2013)

Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigens

scientific article

Dendritic cells exposed to MVA-based HIV-1 vaccine induce highly functional HIV-1-specific CD8(+) T cell responses in HIV-1-infected individuals

scientific article

Detection and typing of molluscum contagiosum virus in skin lesions by using a simple lysis method and polymerase chain reaction

scientific article

Development of a Safe and Effective Vaccinia Virus Oncolytic Vector WR-Δ4 with a Set of Gene Deletions on Several Viral Pathways

scientific article published on 5 December 2017

Differences in virus-induced cell morphology and in virus maturation between MVA and other strains (WR, Ankara, and NYCBH) of vaccinia virus in infected human cells

scientific article

Differential CD4+ versus CD8+ T-cell responses elicited by different poxvirus-based human immunodeficiency virus type 1 vaccine candidates provide comparable efficacies in primates

scientific article published on 9 January 2008

Distinct Immunogenicity and Efficacy of Poxvirus-based Vaccine Candidates against Ebola Virus expressing GP and VP40 Proteins

scientific article published on 7 March 2018

Distinct Roles of Vaccinia Virus NF-κB Inhibitor Proteins A52, B15, and K7 in the Immune Response.

scientific article published on 19 April 2017

Distinct gene expression profiling after infection of immature human monocyte-derived dendritic cells by the attenuated poxvirus vectors MVA and NYVAC.

scientific article

Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-γ production.

scientific article

Diversity in viral anti-PKR mechanisms: a remarkable case of evolutionary convergence

scientific article

EV01: a phase I trial in healthy HIV negative volunteers to evaluate a clade C HIV vaccine, NYVAC-C undertaken by the EuroVacc Consortium.

scientific article

Early virus protein synthesis in vaccinia virus-infected cells

scientific article published in May 1973

Effect of interferon on integrity of vaccinia virus and ribosomal RNA in infected cells.

scientific article published in April 1984

Efficient CD8+ T cell response to the HIV-env V3 loop epitope from multiple virus isolates by a DNA prime/vaccinia virus boost (rWR and rMVA strains) immunization regime and enhancement by the cytokine IFN-gamma

scientific article published in September 2004

Electron microscopic studies of transcriptional complexes released from vaccinia cores during RNA-synthesis in vitro: Methods for fractionation of transcriptional complexes ⬇️

scientific article published on 01 August 1983

Emerging SARS-CoV-2 Variants and Impact in Global Vaccination Programs against SARS-CoV-2/COVID-19

scientific article

Endoplasmic reticulum-Golgi intermediate compartment membranes and vimentin filaments participate in vaccinia virus assembly

scientific article

Enhanced CD8+ T cell immune response against a V3 loop multi-epitope polypeptide (TAB13) of HIV-1 Env after priming with purified fusion protein and booster with modified vaccinia virus Ankara (MVA-TAB) recombinant: a comparison of humoral and cellu

scientific article published in December 2001

Enhanced CD8+ T cell response to HIV-1 env by combined immunization with influenza and vaccinia virus recombinants

scientific article published in February 1999

Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells

scientific article

Enhanced proteolytic processing of the human immunodeficiency virus type 1 envelope protein in murine Ltk(-) cells

scientific article published on January 1995

Enhancement of HIV-1 Env-specific CD8 T cell responses using IFN-Stimulated Gene 15 (ISG15) as an immune adjuvant

scientific article published on 28 October 2020

Enhancing poxvirus vectors vaccine immunogenicity.

scientific article published on January 2014

Expression of the E3L gene of vaccinia virus in transgenic mice decreases host resistance to vaccinia virus and Leishmania major infections.

scientific article

Expression of the firefly luciferase gene in vaccinia virus: a highly sensitive gene marker to follow virus dissemination in tissues of infected animals

scientific article

F11-mediated inhibition of RhoA signalling enhances the spread of vaccinia virus in vitro and in vivo in an intranasal mouse model of infection

scientific article

Full activation of RNaseL in animal cells requires binding of 2-5A within ankyrin repeats 6 to 9 of this interferon-inducible enzyme.

scientific article

Generation and immunogenicity of novel HIV/AIDS vaccine candidates targeting HIV-1 Env/Gag-Pol-Nef antigens of clade C

scientific article published on 06 December 2006

Generation of a dominant 8-MDa deletion at the left terminus of vaccinia virus DNA

scientific article published on May 1985

Glucopyranosyl lipid A adjuvant significantly enhances HIV specific T and B cell responses elicited by a DNA-MVA-protein vaccine regimen

scientific article published in 2014

Growth of Escherichia coli in acetate as a sole carbon source is inhibited by ankyrin-like repeats present in the 2',5'-linked oligoadenylate-dependent human RNase L enzyme.

scientific article published in April 1997

HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140 and Gag-Derived Virus-Like Particles or Lacking the Viral Molecule B19 That Inhibits Type I Interferon Activate Relevant HIV-1-Speci

scientific article published on 8 February 2017

Head-to-Head Comparison of Poxvirus NYVAC and ALVAC Vectors Expressing Identical HIV-1 Clade C Immunogens in Prime-Boost Combination with Env Protein in Nonhuman Primates

scientific article published on 3 June 2015

Head-to-head comparison on the immunogenicity of two HIV/AIDS vaccine candidates based on the attenuated poxvirus strains MVA and NYVAC co-expressing in a single locus the HIV-1BX08 gp120 and HIV-1(IIIB) Gag-Pol-Nef proteins of clade B.

scientific article published on 16 October 2006

Heterologous Combination of VSV-GP and NYVAC Vectors Expressing HIV-1 Trimeric gp145 Env as Vaccination Strategy to Induce Balanced B and T Cell Immune Responses

scientific article published on 18 December 2019

Heterologous prime-boost vaccination with the LACK antigen protects against murine visceral leishmaniasis

scientific article published on August 2005

High quality long-term CD4+ and CD8+ effector memory populations stimulated by DNA-LACK/MVA-LACK regimen in Leishmania major BALB/c model of infection

scientific article

High, broad, polyfunctional, and durable T cell immune responses induced in mice by a novel hepatitis C virus (HCV) vaccine candidate (MVA-HCV) based on modified vaccinia virus Ankara expressing the nearly full-length HCV genome

scientific article published on 17 April 2013

Highly attenuated vaccinia virus mutants for the generation of safe recombinant viruses

scientific article

Host response to the attenuated poxvirus vector NYVAC: upregulation of apoptotic genes and NF-kappaB-responsive genes in infected HeLa cells.

scientific article published on January 2006

Host-range restriction of vaccinia virus E3L deletion mutant can be overcome in vitro, but not in vivo, by expression of the influenza virus NS1 protein

scientific article (publication date: 2011)

Human cytomegalovirus final envelopment on membranes containing both trans-Golgi network and endosomal markers

scientific article

Human gene profiling in response to the active protein kinase, interferon-induced serine/threonine protein kinase (PKR), in infected cells. Involvement of the transcription factor ATF-3 IN PKR-induced apoptosis.

scientific article published on 13 April 2006

Humoral immune response elicited by highly attenuated variants of vaccinia virus and by an attenuated recombinant expressing HIV-1 envelope protein

scientific article published on November 1989

IL-12 and IL-18 act in synergy to clear vaccinia virus infection: involvement of innate and adaptive components of the immune system

scientific article published in August 2003

IL-12 delivery from recombinant vaccinia virus attenuates the vector and enhances the cellular immune response against HIV-1 Env in a dose-dependent manner

scientific article published in June 1999

ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection

scientific article (publication date: 2013)

Identification and characterization of vaccinia virus genes encoding proteins that are highly antigenic in animals and are immunodominant in vaccinated humans

scientific article

Identification of cellular genes induced in human cells after activation of the OAS/RNaseL pathway by vaccinia virus recombinants expressing these antiviral enzymes

scientific article

Identification of functional domains of the interferon-induced enzyme PKR in cells lacking endogenous PKR.

scientific article published on November 1999

Identification of the point mutations in two vaccinia virus nucleoside triphosphate phosphohydrolase I temperature-sensitive mutants and role of this DNA-dependent ATPase enzyme in virus gene expression

scientific article published in February 1990

Immune Modulation of NYVAC-Based HIV Vaccines by Combined Deletion of Viral Genes that Act on Several Signalling Pathways

scientific article

Immune Profiles Identification by Vaccinomics After MVA Immunization in Randomized Clinical Study

scientific article published on 10 November 2020

Immune responses triggered by HIV/AIDS vaccine candidates, derived from MVA-B, with deletions in several immune regulatory genes

scientific article

Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates.

scientific article

Immunization with recombinant DNA and modified vaccinia virus Ankara (MVA) vectors delivering PSCA and STEAP1 antigens inhibits prostate cancer progression.

scientific article published on 21 December 2010

Immunogenic profiling in mice of a HIV/AIDS vaccine candidate (MVA-B) expressing four HIV-1 antigens and potentiation by specific gene deletions

scientific article (publication date: 2010)

Immunogenicity of NYVAC prime-protein boost HIV-1 envelope vaccination and SHIV challenge of nonhuman primates

scientific article published on 7 February 2018

Immunogenicity of Ty-VLP bearing a CD8(+) T cell epitope of the CS protein of P. yoelii: enhanced memory response by boosting with recombinant vaccinia virus

scientific article published in June 2000

Immunogenicity of Ty-VLP bearing a CD8(+) T cell epitope of the CS protein of P. yoelii: enhanced memory response by boosting with recombinant vaccinia virus

scientific article published in March 2000

Improved NYVAC-based vaccine vectors

scientific article (publication date: 2011)

Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors

scientific article (publication date: 15 February 2011)

Improving Adaptive and Memory Immune Responses of an HIV/AIDS Vaccine Candidate MVA-B by Deletion of Vaccinia Virus Genes (C6L and K7R) Blocking Interferon Signaling Pathways

scientific article

Improving recombinant MVA immune responses: potentiation of the immune responses to HIV-1 with MVA and DNA vectors expressing Env and the cytokines IL-12 and IFN-gamma

scientific article

Improving the MVA vaccine potential by deleting the viral gene coding for the IL-18 binding protein

scientific article

In vivo regulation of protein synthesis by phosphorylation of the alpha subunit of wheat eukaryotic initiation factor 2

scientific article published on 01 June 2000

In vivo regulation of the dsRNA-dependent protein kinase PKR by the cellular glycoprotein p67

scientific article (publication date: 26 December 2000)

Indiscriminate degradation of RNAs in interferon-treated, vaccinia virus-infected mouse L cells

scientific article published on September 1984

Inducible expression of the 2-5A synthetase/RNase L system results in inhibition of vaccinia virus replication

scientific article published on January 1997

Inducible expression of the vaccinia virus A17L gene provides a synchronized system to monitor sorting of viral proteins during morphogenesis.

scientific article

Induction of Broad and Polyfunctional HIV-1-Specific T Cell Responses by the Multiepitopic Protein TMEP-B Vectored by MVA Virus

scientific article published on 29 June 2019

Induction of HIV immunity in the genital tract after intranasal delivery of a MVA vector: enhanced immunogenicity after DNA prime-modified vaccinia virus Ankara boost immunization schedule

scientific article published in May 2004

Induction of an anti-viral response and 2′,5′-oligo a synthetase by interferon in several thymidine kinase-deficient cell lines ⬇️

scientific article published on 01 March 1984

Induction of an antiviral response by interferon requires thymidine kinase ⬇️

scientific article published on January 1, 1983

Induction of protective immunity against malaria by priming-boosting immunization with recombinant cold-adapted influenza and modified vaccinia Ankara viruses expressing a CD8+-T-cell epitope derived from the circumsporozoite protein of Plasmodium y

scientific article published on November 2003

Inhibition of early vaccinia virus protein synthesis in interferon-treated chicken embryo fibroblasts

scientific article published in July 1973

Inhibition of protein synthesis by vaccinia virus. III. The effect of ultraviolet-irradiated virus on the inhibition of protein synthesis

scientific article

Inhibition of protein synthesis by vaccinia virus. IV. The role of low-molecular-weight viral RNA in the inhibition of protein synthesis

scientific article

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome

scientific article

Insertion of vaccinia virus C7L host range gene into NYVAC-B genome potentiates immune responses against HIV-1 antigens

scientific article

Insertional inactivation of the vaccinia virus 32-kilodalton gene is associated with attenuation in mice and reduction of viral gene expression in polarized epithelial cells

scientific article published on January 1992

Interferon inhibits marker rescue of vaccinia virus

scientific article published in January 1985

Interferon inhibits viral protein synthesis in L cells infected with vaccinia virus

scientific article published in August 1972

Interferon prevents the generation of spontaneous deletions at the left terminus of vaccinia virus DNA.

scientific article published on October 1985

Interferon treatment inhibits early events in vaccinia virus gene expression in infected mice

scientific article

Interferon-gamma severely inhibits DNA synthesis of vaccinia virus in a macrophage cell line.

scientific article published on February 1994

Interleukin-1- and type I interferon-dependent enhanced immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef vaccine vector with dual deletions of type I and type II interferon-binding proteins

scientific article

Interleukin-12 (IL-12) enhancement of the cellular immune response against human immunodeficiency virus type 1 env antigen in a DNA prime/vaccinia virus boost vaccine regimen is time and dose dependent: suppressive effects of IL-12 boost are mediate

scientific article published on July 2000

Intradermal NKT cell activation during DNA priming in heterologous prime-boost vaccination enhances T cell responses and protection against Leishmania

scientific article

Involvement of PKR and RNase L in translational control and induction of apoptosis after Hepatitis C polyprotein expression from a vaccinia virus recombinant

scientific article

Involvement of the cellular phosphatase DUSP1 in vaccinia virus infection.

scientific article

Isolation and characterization of attenuated mutants of vaccinia virus

scientific article published in August 1987

Isolation and characterization of neutralizing monoclonal antibodies to vaccinia virus

scientific article published on November 1985

Kinetic and phenotypic analysis of CD8+ T cell responses after priming with alphavirus replicons and homologous or heterologous booster immunizations

scientific article

Low Immune Cross-Reactivity between West Nile Virus and a Zika Virus Vaccine Based on Modified Vaccinia Virus Ankara

scientific article published in 2022

MC159L protein from the poxvirus molluscum contagiosum virus inhibits NF-κB activation and apoptosis induced by PKR ⬇️

scientific article published on December 1, 2001

MVA and NYVAC as vaccines against emergent infectious diseases and cancer.

scientific article published on June 2011

MVA-LACK as a safe and efficient vector for vaccination against leishmaniasis

scientific article published on 13 January 2006

Mapping and nucleotide sequence of the vaccinia virus gene that encodes a 14-kilodalton fusion protein

scientific article

Membrane cell fusion activity of the vaccinia virus A17-A27 protein complex

scientific article published on 15 August 2007

Membrane remodelling during vaccinia virus morphogenesis.

scientific article

Microarray analysis reveals characteristic changes of host cell gene expression in response to attenuated modified vaccinia virus Ankara infection of human HeLa cells.

scientific article

Mode of sensitivity and resistance of vaccinia virus replication to interferon.

scientific article published on April 1986

Model for vaccinia virus DNA replication

scientific article

Modification of promoter spacer length in vaccinia virus as a strategy to control the antigen expression

scientific article published on 13 May 2015

Molecular cloning, encoding sequence, and expression of vaccinia virus nucleic acid-dependent nucleoside triphosphatase gene

scientific article

Molecular epidemiology of molluscum contagiosum virus and analysis of the host-serum antibody response in Spanish HIV-negative patients

scientific article (publication date: February 2002)

Mucosal immunization of sheep with a Maedi-Visna virus (MVV) env DNA vaccine protects against early MVV productive infection.

scientific article

Multimeric soluble CD40 ligand (sCD40L) efficiently enhances HIV specific cellular immune responses during DNA prime and boost with attenuated poxvirus vectors MVA and NYVAC expressing HIV antigens

scientific article published on 8 April 2009

NFκB activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses.

scientific article

Nature and mode of action of vaccinia virus products that block activation of the interferon-mediated ppp(A2'p)nA-synthetase

scientific article published in April 1984

Neutrophil and vaccine

scientific article published in January 2015

Neutrophil subtypes shape HIV-specific CD8 T-cell responses after vaccinia virus infection

scientific article published on 12 April 2021

New vaccinia virus promoter as a potential candidate for future vaccines

scientific article published on 28 September 2013

Novel and unexpected role for the tumor suppressor ARF in viral infection surveillance

Novel insights on the progression of intermediate viral forms in the morphogenesis of vaccinia virus.

scientific article published on 24 January 2014

Optimized Hepatitis C Virus (HCV) E2 Glycoproteins and their Immunogenicity in Combination with MVA-HCV

scientific article published on 05 August 2020

P17-07. Insertion of a vaccinia virus host range (hr) gene into NYVAC-B genome potentiates immune responses against HIV-1 antigens.

scientific article published on 22 October 2009

P17-23. Enhanced expression of HIV antigens and improved antigen presentation after infection with replication competent attenuated vaccinia virus in vitro

article

Phosphorylable tyrosine residue 162 in the double-stranded RNA-dependent kinase PKR modulates its interaction with SUMO

scientific article published on 25 October 2017

Plaque size phenotype as a selectable marker to generate vaccinia virus recombinants

scientific article published on February 1989

Potent Anti-hepatitis C Virus (HCV) T Cell Immune Responses Induced in Mice Vaccinated with DNA-Launched RNA Replicons and Modified Vaccinia Virus Ankara-HCV

scientific article published on 21 March 2019

Potent HIV-1-Specific CD8 T Cell Responses Induced in Mice after Priming with a Multiepitopic DNA-TMEP and Boosting with the HIV Vaccine MVA-B

article

Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens

scientific article published on 10 February 2016

Poxvirus vector-based HIV vaccines

scientific article published on September 2010

Poxvirus vectors as HIV/AIDS vaccines in humans

scientific article

Preclinical evaluation of the immunogenicity of C-type HIV-1-based DNA and NYVAC vaccines in the Balb/C mouse model

scientific article published on October 2009

Prime-boost immunization schedules based on influenza virus and vaccinia virus vectors potentiate cellular immune responses against human immunodeficiency virus Env protein systemically and in the genitorectal draining lymph nodes

scientific article

Prime-boost immunization strategies against Chikungunya virus

scientific article

Priming with a potent HIV-1 DNA vaccine frames the quality of immune responses prior to a poxvirus and protein boost

article

Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malaria

scientific article

Procedure for purification of intact DNA from vaccinia virus

scientific article published on January 1978

Proceedings of the Frontiers of Retrovirology Conference 2016.

scientific article published on 26 September 2016

Prostaglandin A inhibits the replication of vesicular stomatitis virus: effect on virus glycoprotein

scientific article published in December 1983

Protection in dogs against visceral leishmaniasis caused by Leishmania infantum is achieved by immunization with a heterologous prime-boost regime using DNA and vaccinia recombinant vectors expressing LACK

scientific article published on 01 June 2003

Protective immune response against cutaneous leishmaniasis by prime/booster immunization regimens with vaccinia virus recombinants expressing Leishmania infantum p36/LACK and IL-12 in combination with purified p36.

scientific article published in July 2001

Quantification of antigen specific CD8+ T cells using an ELISPOT assay

scientific article published in April 1995

Reasons for not participating in a phase 1 preventive HIV vaccine study in a resource-rich country

scientific article published on 13 June 2012

Recombinant poxviruses as mucosal vaccine vectors

scientific article

Recombinant proteins produced by vaccinia virus vectors can be incorporated within the virion (IMV form) into different compartments.

scientific article

Recombinant viruses expressing a human malaria antigen can elicit potentially protective immune CD8+ responses in mice

scientific article

Regulated expression of nuclear genes by T3 RNA polymerase and lac repressor, using recombinant vaccinia virus vectors

scientific article published on October 1990

Regulated expression of the interferon-induced protein kinase p68 (PKR) by vaccinia virus recombinants inhibits the replication of vesicular stomatitis virus but not that of poliovirus

scientific article published on December 1996

Regulation of the tumor suppressor PTEN by SUMO.

scientific article

Regulation of vaccinia virus E3 protein by small ubiquitin-like modifier proteins

scientific article published on 28 September 2011

Removal of the C6 Vaccinia Virus Interferon-β Inhibitor in the Hepatitis C Vaccine Candidate MVA-HCV Elicited in Mice High Immunogenicity in Spite of Reduced Host Gene Expression

article

Removal of vaccinia virus genes that block interferon type I and II pathways improves adaptive and memory responses of the HIV/AIDS vaccine candidate NYVAC-C in mice

scientific article

Replication of Vaccinia DNA and Studies on the Structure of the Viral Chromosome ⬇️

scientific article published on January 1, 1979

Replication of vaccinia DNA in mouse L cells. II. In vitro DNA synthesis in cytoplasmic extracts

scientific article

Replication of vaccinia DNA in mouse L cells. III. Intracellular forms of viral DNA.

scientific article published in October 1977

Replication of vaccinia DNA in mouse L cells. IV. Protein synthesis and viral DNA replication

scientific article published on May 15, 1978

Replication-competent NYVAC-KC yields improved immunogenicity to HIV-1 antigens in rhesus macaques, compared to non-replicating NYVAC

article

Resistance of vaccinia virus to interferon is related to an interference phenomenon between the virus and the interferon system

scientific article published in April 1984

Resistance to viral infection of super p53 mice.

scientific article published in April 2005

Rifampin and vaccinia DNA ⬇️

scientific article published on February 1, 1977

Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys

scientific article

SIRT1 stabilizes PML promoting its sumoylation

scientific article

Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02).

scientific article published on 09 September 2011

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

scientific article published on 26 February 2015

Safety and immunogenicity of a multivalent HIV vaccine comprising envelope protein with either DNA or NYVAC vectors (HVTN 096): a phase 1b, double-blind, placebo-controlled trial

scientific article published on 07 October 2019

Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization.

scientific article published on 24 October 2017

Selective induction of host genes by MVA-B, a candidate vaccine against HIV/AIDS

scientific article published on 9 June 2010

Selective inhibition of protein synthesis by synthetic and vaccinia virus-core synthesized poly(riboadenylic acids).

scientific article

Selective inhibition of viral gene expression as the mechanism of the antiviral action of PGA1 in vaccinia virus-infected cells.

scientific article

Sequence analysis of a Molluscum contagiosum virus DNA region which includes the gene encoding protein kinase 2 and other genes with unique organization

scientific article

Stability of vaccinia virus DNA during persistent infections: accumulation of left-end deletions and of tandem repeats at both ends of the viral genome and prevention by interferon

scientific article

Structural and functional characterization of a cell surface binding protein of vaccinia virus.

scientific article published on January 1990

Structural and functional properties of the 14-kDa envelope protein of vaccinia virus synthesized in Escherichia coli

scientific article published in December 1990

Structural and functional studies of a 39,000-Mr immunodominant protein of vaccinia virus.

scientific article

Structural properties of HIV-1 Env fused with the 14-kDa vaccinia virus envelope protein

scientific article published in April 1991

Structure of vaccinia DNA: analysis of the viral genome by restriction endonucleases

scientific article published on May 1978

Studies concerning the structure and organization of the vaccinia virus nucleoid. I. Isolation and characterization of subviral particles prepared by treating virions with guanidine-HCL, nonidet-P40, and 2-mercaptoethanol

scientific article published in December 1979

Studies on the Mechanisms of Vaccinia Virus Cytopathic Effects: I. Inhibition of Protein Synthesis in Infected Cells is Associated with Virus-induced RNA Synthesis

scientific article published on June 1, 1978

Studies on the mechanism of entry of vaccinia virus in animal cells

scientific article published on January 1987

Studies on the mechanisms of vaccinia virus cytopathic effects. II. Early cell rounding is associated with virus polypeptide synthesis

scientific article published in June 1978

Subcellular forms and biochemical events triggered in human cells by HCV polyprotein expression from a viral vector

scientific article (publication date: 15 September 2008)

Suppression of NYVAC Infection in HeLa Cells Requires RNase L but Is Independent of Protein Kinase R Activity

scientific article

Synthetic long peptide booster immunization in rhesus macaques primed with replication-competent NYVAC-C-KC induces a balanced CD4/CD8 T-cell and antibody response against the conserved regions of HIV-1.

scientific article published on 9 February 2015

Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C.

scientific article

T-cell immune responses against Env from CRF12_BF and subtype B HIV-1 show high clade-specificity that can be overridden by multiclade immunizations

scientific article

TRAF family proteins link PKR with NF-kappa B activation

scientific article

Tauopathy Analysis in P301S Mouse Model of Alzheimer Disease Immunized With DNA and MVA Poxvirus-Based Vaccines Expressing Human Full-Length 4R2N or 3RC Tau Proteins

scientific article published on 13 March 2020

The 2-5A system and vaccinia virus.

scientific article published on January 1985

The 32-kilodalton envelope protein of vaccinia virus synthesized in Escherichia coli binds with specificity to cell surfaces

scientific article published on January 1991

The A17L gene product of vaccinia virus is exposed on the surface of IMV.

scientific article published on November 2001

The ESCRT machinery is not required for human cytomegalovirus envelopment

scientific article published on 29 August 2007

The Envelope-Based Fusion Antigen GP120C14K Forming Hexamer-Like Structures Triggers T Cell and Neutralizing Antibody Responses Against HIV-1

scientific article published on 04 December 2019

The HIV/AIDS vaccine candidate MVA-B administered as a single immunogen in humans triggers robust, polyfunctional, and selective effector memory T cell responses to HIV-1 antigens.

scientific article published on 24 August 2011

The Interferon-Induced Double-Stranded RNA-Activated Human p68 Protein Kinase Potently Inhibits Protein Synthesis in Cultured Cells

scientific article published on 01 January 1993

The apoptosis pathway triggered by the interferon-induced protein kinase PKR requires the third basic domain, initiates upstream of Bcl-2, and involves ICE-like proteases

scientific article published on 01 April 1997

The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.

scientific article published in January 2001

The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells

scientific article

The combination of DNA vectors expressing IL-12 + IL-18 elicits high protective immune response against cutaneous leishmaniasis after priming with DNA-p36/LACK and the cytokines, followed by a booster with a vaccinia virus recombinant expressing p36

scientific article published in February 2003

The combined vaccination protocol of DNA/MVA expressing Zika virus structural proteins as efficient inducer of T and B cell immune responses

The effect of interferon on the formation of virus polyribosomes in L cells infected with vaccinia virus

scientific article published in May 1975

The evolution of poxvirus vaccines

scientific article

The formation of virus polyribosomes in L cells infected with vaccinia virus

scientific article

The impact of PKR activation: from neurodegeneration to cancer.

scientific article published on 12 February 2014

The interferon system and vaccinia virus evasion mechanisms

scientific article published on September 2009

The interferon-induced double-stranded RNA-activated human p68 protein kinase inhibits the replication of vaccinia virus

scientific article published on April 1993

The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis

scientific article published on 01 March 1994

The interferon-induced protein kinase (PKR), triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors.

scientific article published on July 2000

The latency protein LANA2 from Kaposi's sarcoma-associated herpesvirus inhibits apoptosis induced by dsRNA-activated protein kinase but not RNase L activation

scientific article published on June 2003

The major core protein P4a (A10L gene) of vaccinia virus is essential for correct assembly of viral DNA into the nucleoprotein complex to form immature viral particles.

scientific article published on July 2001

The poxvirus vectors MVA and NYVAC as gene delivery systems for vaccination against infectious diseases and cancer.

scientific article published on April 2008

The purified 14-kilodalton envelope protein of vaccinia virus produced in Escherichia coli induces virus immunity in animals.

scientific article published on October 1991

The relationship between the antiviral action of interferon and prostaglandins in virus-infected murine cells ⬇️

scientific article published on October 31, 1983

The translation of vaccinia virus messenger RNA in animal cell-free systems

scientific article published in March 1973

The vaccinia virus 14-kilodalton fusion protein forms a stable complex with the processed protein encoded by the vaccinia virus A17L gene.

scientific article published on June 1993

The vaccinia virus 39-kDa protein forms a stable complex with the p4a/4a major core protein early in morphogenesis

scientific article

Thymidine kinase genes and the induction of anti-rival responses by interferon ⬇️

scientific article published on 01 July 1983

Tissue distribution of the Ankara strain of vaccinia virus (MVA) after mucosal or systemic administration ⬇️

scientific article published on May 1, 2003

Topography of vaccinia virus DNA.

scientific article

Use of persistent infections with vaccinia virus recombinants to introduce alterations in foreign proteins: an application to HIV-1 env protein

scientific article published on December 1996

Vaccine efficacy against malaria by the combination of porcine parvovirus-like particles and vaccinia virus vectors expressing CS of Plasmodium

scientific article (publication date: 2012)

Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates

scientific article published on 27 May 2015

Vaccinia Virus E3L Protein Is an Inhibitor of the Interferon (IFN)-Induced 2-5A Synthetase Enzyme ⬇️

scientific article published on April 10, 1998

Vaccinia virus 15-kilodalton (A14L) protein is essential for assembly and attachment of viral crescents to virosomes

scientific article published on February 1998

Vaccinia virus A17L gene product is essential for an early step in virion morphogenesis

scientific article published in August 1995

Vaccinia virus E3 protein prevents the antiviral action of ISG15

scientific article

Vaccinia virus induces cell fusion at acid pH and this activity is mediated by the N-terminus of the 14-kDa virus envelope protein

scientific article

Vaccinia virus membrane proteins p8 and p16 are cotranslationally inserted into the rough endoplasmic reticulum and retained in the intermediate compartment

scientific article

Vaccinia virus preferentially enters polarized epithelial cells through the basolateral surface

scientific article published on January 1991

Vaccinia virus transcription: hybridization of mRNA to restriction fragments of vaccinia DNA.

scientific article published in May 1978

Vector replication and expression of HIV-1 antigens by the HIV/AIDS vaccine candidate MVA-B is not affected by HIV-1 protease inhibitors

scientific article

Virological and immunological characterization of novel NYVAC-based HIV/AIDS vaccine candidates expressing clade C trimeric soluble gp140(ZM96) and Gag(ZM96)-Pol-Nef(CN54) as virus-like particles.

scientific article

Virological and immunological outcome of treatment interruption in HIV-1-infected subjects vaccinated with MVA-B.

scientific article published on 27 September 2017

Virus attenuation and identification of structural proteins of vaccinia virus that are selectively modified during virus persistence

scientific article published on August 1987

Virus distribution of the attenuated MVA and NYVAC poxvirus strains in mice

scientific article

Virus infection rapidly activates the P58IPK pathway, delaying peak kinase activation to enhance viral replication ⬇️

scientific article published on May 25, 2011

Visna/maedi virus Env protein expressed by a vaccinia virus recombinant induces cell-to-cell fusion in cells of different origins in the apparent absence of Env cleavage: role of glycosylation and of proteoglycans

scientific article (publication date: December 2002)

Wiskott-Aldrich syndrome protein is needed for vaccinia virus pathogenesis

scientific article published on February 2005

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