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List of works by Elina Hyppönen

25-Hydroxyvitamin D Concentration and Leukocyte Telomere Length in Young Adults: Findings From the Northern Finland Birth Cohort 1966.

scientific article

25-Hydroxyvitamin D and cognitive performance in mid-life

scientific article

25-Hydroxyvitamin D and pre-clinical alterations in inflammatory and hemostatic markers: a cross sectional analysis in the 1958 British Birth Cohort

scientific article

25-hydroxyvitamin D, APOE ɛ4 genotype and cognitive function: findings from the 1958 British birth cohort

scientific article published on 8 October 2014

25-hydroxyvitamin D, IGF-1, and metabolic syndrome at 45 years of age: a cross-sectional study in the 1958 British Birth Cohort

scientific article published on 14 November 2007

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

scientific article published on 18 June 2015

A genome-wide association meta-analysis identifies new childhood obesity loci

scientific article

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

scientific article published on 01 October 2019

APOA5 genotype influences the association between 25-hydroxyvitamin D and high density lipoprotein cholesterol

scientific article published on 13 February 2013

Adiposity, vitamin D requirements, and clinical implications for obesity-related metabolic abnormalities

scientific article published on 01 September 2018

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

scientific article published in December 2016

An intergenerational and lifecourse study of health and mortality risk in parents of the 1958 birth cohort: (II) mortality rates and study representativeness

scientific article published in July 2005

An intergenerational study of birthweight: investigating the birth order effect

scientific article published on 01 April 2004

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

scientific article

Association between major depressive disorder and multiple disease outcomes: a phenome-wide Mendelian randomisation study in the UK Biobank

scientific article published on 19 August 2019

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

scientific article published on 04 September 2019

Association of Lifestyle and Genetic Risk With Incidence of Dementia

scientific article published on 14 July 2019

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

scientific article published on 30 October 2018

Association of supplemental calcium and dairy milk intake with all-cause and cause-specific mortality in the UK Biobank: a prospective cohort study

scientific article published on 29 November 2019

Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes

scientific article published on 2 July 2007

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

scientific article

Associations between parental and offspring adiposity up to midlife: the contribution of adult lifestyle factors in the 1958 British Birth Cohort Study

scientific article published on 11 August 2010

Associations of childhood 25-hydroxyvitamin D2 and D3 and cardiovascular risk factors in adolescence: prospective findings from the Avon Longitudinal Study of Parents and Children

scientific article published on 26 November 2012

Associations of genetically determined iron status across the phenome: A mendelian randomization study.

scientific article published on 20 June 2019

Avoidance of vitamin D deficiency in pregnancy in the United Kingdom: the case for a unified approach in National policy

scientific article published on 2 July 2010

Birth weight and risk of type 2 diabetes: a systematic review

scientific article published in December 2008

Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis

scientific article

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

scientific article (publication date: 2013)

Childhood hardship, maternal smoking, and birth outcomes: a prospective cohort study

scientific article

Common Genetic Determinants of Vitamin D Insufficiency: A Genome-Wide Association Study

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

scientific article published on 30 July 2011

Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis

scientific article

Correction: Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.

scientific article published on 24 September 2013

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on November 2016

Cow's milk consumption, HLA-DQB1 genotype, and type 1 diabetes: a nested case-control study of siblings of children with diabetes. Childhood diabetes in Finland study group

scientific article published on 01 June 2000

Cow's milk consumption, disease-associated autoantibodies and type 1 diabetes mellitus: a follow-up study in siblings of diabetic children. Childhood Diabetes in Finland Study Group

scientific article published in September 1998

DHCR7 mutations linked to higher vitamin D status allowed early human migration to northern latitudes ⬇️

scientific article

Daily supplementation with 15 μg vitamin D2 compared with vitamin D3 to increase wintertime 25-hydroxyvitamin D status in healthy South Asian and white European women: a 12-wk randomized, placebo-controlled food-fortification trial

scientific article published on 5 July 2017

Death of siblings in childhood and subsequent mortality: prospective observational study

scientific article published on 30 October 2014

Deaths of children aged under 5 years and related factors in the Islamic Republic of Iran: a populationbased case-control study.

scientific article published on 25 September 2016

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Depression increases the genetic susceptibility to high body mass index: Evidence from UK Biobank

scientific article published on 14 October 2019

Determinants of vitamin D status: focus on genetic variations.

scientific article published on July 2011

Diabetes risk in British adults in mid life: a national prevalence study of glycated haemoglobin

scientific article published in March 2007

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Does vitamin D supplementation in infancy reduce the risk of pre-eclampsia?

scientific article published on 31 January 2007

Early-life nutritional exposures and lifelong health: immediate and long-lasting impacts of probiotics, vitamin D, and breastfeeding

scientific article published on 27 January 2017

Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomization Meta-Analysis in the CARTA Consortium

scientific article

Effects of grandmothers' smoking in pregnancy on birth weight: intergenerational cohort study.

scientific article

Environmental and genetic determinants of vitamin D status among older adults in London, UK.

scientific article published on 14 January 2016

Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

article

Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D

scientific article (publication date: 2012)

Evidence for a genetic interaction in allergy-related responsiveness to vitamin D deficiency

scientific article published on 12 June 2012

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

scientific article published on 04 September 2019

Genetic association analysis of vitamin D pathway with obesity traits.

scientific article published on 05 February 2013

Genetic evidence of assortative mating in humans

scholarly article

Genetic loci influencing kidney function and chronic kidney disease

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip

scientific article published on 28 April 2011

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on 18 April 2016

Genetic variants influencing biomarkers of nutrition are not associated with cognitive capability in middle-aged and older adults

scientific article published on 06 March 2013

Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight

scientific article

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

scientific article published on 7 September 2022

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

scientific article published on 24 November 2015

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

scientific article

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

scientific article published on 17 January 2018

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.

scientific article

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

scientific article

Genotype-covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model

scientific article published on 20 May 2019

Gestational and Early Infancy Exposure to Margarine Fortified with Vitamin D through a National Danish Programme and the Risk of Type 1 Diabetes: The D-Tect Study

scientific article published on June 2015

Global Consensus Recommendations on Prevention and Management of Nutritional Rickets

scientific article

Global Consensus Recommendations on Prevention and Management of Nutritional Rickets

scientific article published on 8 January 2016

Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants.

scientific article

Harmonization Study Between LC-MS/MS and Diasorin RIA for Measurement of 25-Hydroxyvitamin D Concentrations in a Large Population Survey

scientific article

Health effects associated with serum calcium concentrations: evidence from MR-PheWAS analysis in UK Biobank

scientific article published on 08 August 2019

Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

scientific article

High-Dose Vitamin D Supplements Are Not Associated with Linear Growth in a Large Finnish Cohort

scientific article published on 23 March 2011

Hypothesis‐free discovery of novel cancer predictors using machine learning

scientific article published in 2023

Infant feeding patterns in the Finnish type I diabetes prediction and prevention nutrition study cohort

scientific article published on 01 January 2005

Infant feeding, early weight gain, and risk of type 1 diabetes. Childhood Diabetes in Finland (DiMe) Study Group

scientific article

Information bias in measures of self-reported physical activity

article

Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes

scientific article published on 25 March 2011

Inhibition of cytokine secretion from adipocytes by 1,25-dihydroxyvitamin D3 via the NF-κB pathway

scientific article published on 13 July 2012

Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study

scientific article (publication date: 3 November 2001)

Interaction between allelic variations in vitamin D receptor and retinoid X receptor genes on metabolic traits

scientific article

Interaction between vitamin D receptor gene polymorphisms and 25-hydroxyvitamin D concentrations on metabolic and cardiovascular disease outcomes

scientific article

Investigating the association of vitamin D seasonality on inflammatory and hemostatic markers

scientific article published on 11 June 2013

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

scientific article

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

scientific article published on 7 October 2014

List of Contributors

Long-term coffee consumption, caffeine metabolism genetics, and risk of cardiovascular disease: a prospective analysis of up to 347,077 individuals and 8368 cases

scientific article published on 01 March 2019

Maternal Hb during pregnancy and offspring's educational achievement: a prospective cohort study over 30 years

scientific article published on 4 June 2010

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

scientific article published on 07 May 2020

Micronutrients and the risk of type 1 diabetes: vitamin D, vitamin E, and nicotinamide.

scientific article published in September 2004

Month of birth, vitamin D and risk of immune-mediated disease: a case control study

scientific article

Need to be implemented in UK

scientific article published in the British Medical Journal

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

scientific article published on 2 December 2012

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

scientific article published on 12 October 2020

Obesity and depressive symptoms in mid-life: a population-based cohort study

scientific article published on 17 September 2018

Obesity and type 2 diabetes risk in midadult life: the role of childhood adversity

scientific article published in May 2008

Obesity, increased linear growth, and risk of type 1 diabetes in children

scientific article

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016

Parental and offspring adiposity associations: insights from the 1958 British birth cohort

scientific article published on 15 June 2011

Parental diabetes and birth weight of offspring: intergenerational cohort study.

scientific article

Parental growth at different life stages and offspring birthweight: an intergenerational cohort study

article published in 2004

Parental obesity and risk factors for cardiovascular disease among their offspring in mid-life: findings from the 1958 British Birth Cohort Study.

scientific article published on 09 April 2013

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Physical Activity, APOE Genotype, and Cognitive Decline: Exploring Gene-Environment Interactions in the UK Biobank

scientific article published on 01 January 2019

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

scientific article

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

scientific article published on 15 January 2016

Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

scientific article (publication date: 2013)

Potential determinants of vitamin D in Finnish adults: a cross-sectional study from the Northern Finland birth cohort 1966.

scientific article published on 06 March 2017

Prenatal Growth, BMI, and Risk of Type 2 Diabetes by Early Midlife

scientific article published on 01 September 2003

Prenatal exposures and glucose metabolism in adulthood: are effects mediated through birth weight and adiposity?

scientific article published on 2 February 2007

Prenatal growth and risk of occlusive and haemorrhagic stroke in Swedish men and women born 1915-29: historical cohort study

scientific article

Prevalence, determinants and clinical correlates of vitamin D deficiency in adults with inhaled corticosteroid-treated asthma in London, UK.

scientific article published on 4 November 2016

Prevalence, determinants and clinical correlates of vitamin D deficiency in patients with Chronic Obstructive Pulmonary Disease in London, UK.

scientific article published in February 2017

Preventing Vitamin D Deficiency in Pregnancy – Importance for the Mother and Child

scientific article published on 25 November 2011

Proceedings of the Rank Forum on Vitamin D.

scientific article

Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans

scientific article published on 09 June 2016

Reply to PA Atroszko

scientific article published on 01 November 2019

Schizophrenia and co-morbidity risk: Evidence from a data driven phenomewide association study

scientific article published in 2023

Serum 25-Hydroxyvitamin D Status and Longitudinal Changes in Weight and Waist Circumference: Influence of Genetic Predisposition to Adiposity.

scientific article

Serum 25-hydroxyvitamin D and IgE - a significant but nonlinear relationship

scientific article

Serum 25-hydroxyvitamin D measurement in a large population survey with statistical harmonization of assay variation to an international standard

scientific article published on 28 August 2007

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers

scientific article published on 4 December 2014

The D2-D3 Study: a randomised, double-blind, placebo-controlled food-fortification trial in women, comparing the efficacy of 15ug/d vitamin D2 vs vitamin D3 in raising serum 25OHD levels

The D2-D3 Study: comparing the efficacy of 15μg/d vitamin D2 vs. D3 in raising vitamin D status in both South Asian and Caucasian women, and the ethical implications of placebo treatment

article

The impact of low-frequency and rare variants on lipid levels

scientific article published on 11 May 2015

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

scientific article (publication date: 2013)

Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individuals

scientific article published on 23 April 2007

Using genetics to understand the causal influence of higher BMI on depression

article

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

scientific article

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

article

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

scientific article published on 02 September 2019

Vitamin D Status and Glucose Homeostasis in the 1958 British Birth Cohort: The role of obesity

article by Elina Hyppönen & C. Power published 26 September 2006 in Diabetes Care

Vitamin D and adipose tissue-more than storage

scientific article

Vitamin D and chronic widespread pain in a white middle-aged British population: evidence from a cross-sectional population survey

scientific article published on 12 August 2008

Vitamin D and cognitive function: A Mendelian randomisation study

scientific article published on 16 October 2017

Vitamin D and common mental disorders in mid-life: cross-sectional and prospective findings

scientific article published on 21 January 2013

Vitamin D and multiple sclerosis hospital admissions in Scotland.

scientific article published on 29 June 2011

Vitamin D for the prevention of preeclampsia? A hypothesis.

scientific article

Vitamin D fortification and seasonality of birth in type 1 diabetic cases: D-tect study

scientific article published on 27 October 2015

Vitamin D fortification and seasonality of birth in type 1 diabetic cases: D-tect study – ERRATUM

scientific article published on 18 April 2016

Vitamin D serum levels and allergic rhinitis

scientific article published on 01 September 2007

Vitamin D status has a linear association with seasonal infections and lung function in British adults

scientific article published on 6 June 2011

Vitamin D: do we get enough? A discussion between vitamin D experts in order to make a step towards the harmonisation of dietary reference intakes for vitamin D across Europe.

scientific article published on 11 December 2012

Which Risk Factors Causally Influence Dementia? A Systematic Review of Mendelian Randomization Studies.

scientific article published in January 2018

Working patterns and vitamin D status in mid-life: a cross-sectional study of the 1958 British birth cohort.

scientific article

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