Search filters

List of works by Karl-Heinz Herzig

(Neuro) Peptides, Physical Activity, and Cognition

scientific article published on 10 August 2020

A dietary biomarker approach captures compliance and cardiometabolic effects of a healthy Nordic diet in individuals with metabolic syndrome.

scientific article

A high intake of dietary fiber influences C-reactive protein and fibrinogen, but not glucose and lipid metabolism, in mildly hypercholesterolemic subjects ⬇️

scientific article published on 07 February 2013

A polygenic biomarker to identify patients with severe hypercholesterolemia of polygenic origin

scientific article published on 19 April 2020

A psyllium fiber-enriched meal strongly attenuates postprandial gastrointestinal peptide release in healthy young adults

scientific article published on 10 February 2010

Acid steatocrit determination is not helpful in cystic fibrosis patients without or with mild steatorrhea.

scientific article

Adherence to the Nordic Nutrition Recommendations in a Nordic population with metabolic syndrome: high salt consumption and low dietary fibre intake (The SYSDIET study).

scientific article published on 16 December 2013

Adipocyte-derived extracellular vesicles as new communication signals in the regulation of food intake

scientific article published on 26 November 2019

Adipokines and inflammatory markers in elderly subjects with high risk of type 2 diabetes and cardiovascular disease

scientific article published in Scientific Reports

Adipose gene expression profiles reveal insights into the adaptation of northern Eurasian semi-domestic reindeer (Rangifer tarandus)

scientific article published on 07 October 2021

Adipose tissue INSR splicing in humans associates with fasting insulin level and is regulated by weight loss

scientific article published on 7 November 2013

Alterations in serum amino-acid profile in the progression of colorectal cancer: associations with systemic inflammation, tumour stage and patient survival

scientific article published on 19 December 2018

An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study

scientific article published on 03 December 2019

Ancient DNA suggests modern wolves trace their origin to a Late Pleistocene expansion from Beringia

scientific article published on 16 December 2019

Antimicrobial peptides in chronic anal fistula epithelium

scientific article published on 01 September 2007

App-assured essential physical activity for the prevention of cognitive decline: changing paradigms in public health – a study protocol for a randomised controlled trial

scientific article published on 1 September 2021

Association of Body Mass Index with Fecal Microbial Diversity and Metabolites in the Northern Finland Birth Cohort

scientific article published on 27 August 2020

Association of Physical Activity With Telomere Length Among Elderly Adults - The Oulu Cohort 1945

scientific article published on 24 April 2019

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

scientific article

CCK-stimulated changes in pancreatic acinar morphology are mediated by rho

scientific article published on 01 January 2002

Cardiac repolarization and autonomic regulation during short-term cold exposure in hypertensive men: an experimental study

scientific article

Cardiovascular effects of ghrelin antagonist in conscious rats.

scientific article published on 6 May 2009

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

scientific article (publication date: 2013)

Central aortic blood pressure of hypertensive men during short-term cold exposure

scientific article published on 20 August 2013

Changing Incidence of Acute Appendicitis and Nonspecific Abdominal Pain Between 1987 and 2007 in Finland ⬇️

scientific article published on April 1, 2011

Characteristics and significance of colorectal cancer associated lymphoid reaction

scientific article

Chronic pouchitis is not related to small intestine bacterial overgrowth

scientific article published in August 2008

Circadian rhythms-Daylight saving time, health and body clocks

scientific article published on 14 December 2018

Co-delivery of a hydrophobic small molecule and a hydrophilic peptide by porous silicon nanoparticles.

scientific article published on 10 June 2013

Cohort Profile: The DynaHEALTH consortium - a European consortium for a life-course bio-psychosocial model of healthy ageing of glucose homeostasis

scientific article published on 01 August 2019

Cold exposure enhances fat utilization but not non-esterified fatty acids, glycerol or catecholamines availability during submaximal walking and running

scientific article published on 10 May 2013

Comparison of Subjective and Objective Methods to Measure the Physical Activity of Non-Depressed Middle-Aged Healthy Subjects with Normal Cognitive Function and Mild Cognitive Impairment-A Cross-Sectional Study

scientific article

Concentrated arabinoxylan but not concentrated β-glucan in wheat bread has similar effects on postprandial insulin as whole-grain rye in porto-arterial catheterized pigs

scientific article published on 6 August 2013

Could vitamin D reduce obesity-associated inflammation? Observational and Mendelian randomization study

scientific article published on 31 March 2020

Cross-linking of sodium caseinate-structured emulsion with transglutaminase alters postprandial metabolic and appetite responses in healthy young individuals

article

Crosslinking with transglutaminase does not change metabolic effects of sodium caseinate in model beverage in healthy young individuals

scientific article

DNA methylation links prenatal smoking exposure to later life health outcomes in offspring

scientific article published on 01 July 2019

Dairy products influence gut hormone secretion and appetite differently: A randomized controlled crossover trial

scientific article published on 20 November 2019

Decreased preoperative serum 25-Hydroxyvitamin D levels in colorectal cancer are associated with systemic inflammation and serrated morphology

scientific article

Development of porous silicon nanocarriers for parenteral peptide delivery

scientific article published on 07 December 2012

Diazepam binding inhibitor overexpression in mice causes hydrocephalus, decreases plasticity in excitatory synapses and impairs hippocampus-dependent learning

scientific journal article

Differential activation of p42ERK2 and p125FAK by cholecystokinin and bombesin in the secretion and proliferation of the pancreatic amphicrine cell line AR42J.

scientific article published on January 2002

Differential effects of dietary protein sources on postprandial low-grade inflammation after a single high fat meal in obese non-diabetic subjects

scientific article published on 19 October 2011

Differential regulated expression of keratinocyte growth factor and its receptor in experimental and human liver fibrosis

scientific article published on 03 July 2007

Dipeptidyl peptidase 4 and GLP-1 interplay in STC-1 and GLUTag cell lines

scientific article published on 27 September 2020

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Distinct effects of calorie restriction and resveratrol on diet-induced obesity and Fatty liver formation

scientific article

Downregulation of PPARs and SREBP by acyl-CoA-binding protein overexpression in transgenic rats

scientific article published on 22 December 2007

Early decline of pancreatic function in cystic fibrosis patients with class 1 or 2 CFTR mutations

scientific article published on 01 February 2005

Early determinants of metabolically healthy obesity in young adults: study of the Northern Finland Birth Cohort 1966

scientific article published on 24 May 2018

Effect of Physical Activity on Plasma PCSK9 in Subjects With High Risk for Type 2 Diabetes

Effect of isotonic solutions and peptide adsorption on zeta potential of porous silicon nanoparticle drug delivery formulations

scientific article published on 28 April 2012

Effect of physical activity on pulse wave velocity in elderly subjects with normal glucose, prediabetes or Type 2 Diabetes.

scientific article

Effect of surface chemistry of porous silicon microparticles on glucagon-like peptide-1 (GLP-1) loading, release and biological activity

scientific article

Effect of the fat composition of a single high-fat meal on inflammatory markers in healthy young women

scientific article published on 7 June 2011

Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study

scientific article published on 17 March 2016

Effects of a healthy Nordic diet on plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome: a randomized, placebo-controlled trial (SYSDIET)

scientific article published on 26 February 2014

Effects of polydextrose with breakfast or with a midmorning preload on food intake and other appetite-related parameters in healthy normal-weight and overweight females: An acute, randomized, double-blind, placebo-controlled, and crossover study.

scientific article published in December 2016

Elevated resting metabolic rates among female, but not male, reindeer herders from subarctic Finland

scientific article published on 27 June 2020

Elevated serum S-100β in patients with septic shock is associated with delirium

scientific article published on 05 August 2018

Epigenomic Modifications in Modern and Ancient Genomes

scientific article published on 20 January 2022

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Exocrine pancreatic function in children with progressive familial intrahepatic cholestasis type 2

scientific article published on 01 April 2006

Expression of functional prolactin and its receptor in human colorectal cancer

scientific article published on 27 June 2002

Expression of keratinocyte growth factor and its receptor in adaptive changes of ileorectal pouch mucosa

scientific article published in September 2005

Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue

scientific article

Fecal elastase-1 is superior to fecal chymotrypsin in the assessment of pancreatic involvement in cystic fibrosis

scientific article published in July 2002

Fecal pancreatic elastase-1 levels in older individuals without known gastrointestinal diseases or diabetes mellitus

scientific article

Fecal pyruvate kinase (M2-PK): a new predictor for inflammation and severity of pouchitis.

scientific article

Fecal pyruvate kinase: a potential new marker for intestinal inflammation in children with inflammatory bowel disease

scientific article published on 01 October 2007

Fuel selection during short-term submaximal treadmill exercise in the cold is not affected by pre-exercise low-intensity shivering.

scientific article

Full-length visfatin levels are associated with inflammation in women with polycystic ovary syndrome

article by Taina K Lajunen et al published March 2012 in European Journal of Clinical Investigation

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

scientific article published on 04 September 2019

Gene regulatory potential of nonsteroidal vitamin D receptor ligands

scientific article published on 28 April 2005

Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

Genetic evidence of assortative mating in humans

article

Genetic study of circulating cytokines offers insight into the determinants, cascades and effects of systemic inflammation

scientific article

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns

scientific article published on 19 June 2019

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns:

Gunnar Flemström's legacy in intestinal bicarbonate secretion-A homage to Gunnar Flemström and his work in intestinal bicarbonate secretion

scientific article published on 19 June 2019

HIF Prolyl 4-Hydroxylase-2 Inhibition Improves Glucose and Lipid Metabolism and Protects Against Obesity and Metabolic Dysfunction

scientific article published on 01 May 2014

HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD

scientific article published on 15 April 2020

Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with Metabolic Syndrome-A SYSDIET Sub-Study

scientific article published on 09 April 2019

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome

scientific article

High Home Blood Pressure Variability Associates With Exaggerated Blood Pressure Response to Cold Stress

scientific article published on 01 May 2019

High-serum MMP-8 levels are associated with decreased survival and systemic inflammation in colorectal cancer

scientific article published on 29 May 2018

Human information behaviour and physiological measurements as a basis to tailor health information. An explorative study in a physical activity intervention among prediabetic individuals in Northern Finland

scientific article published in November 2011

Hypertension Does Not Alter the Increase in Cardiac Baroreflex Sensitivity Caused by Moderate Cold Exposure

scientific article published on 02 June 2016

Hypocholesterolemic Effect of the Lignin-Rich Insoluble Residue of Brewer's Spent Grain in Mice Fed a High-Fat Diet

scientific article published on 15 January 2019

Increased Serum PAI-1 Levels in Subjects with Metabolic Syndrome and Long-Term Adverse Mental Symptoms: A Population-Based Study

scientific article

Increased protein intake affects pro-opiomelanocortin (POMC) processing, immune function and IGF signaling in peripheral blood mononuclear cells of home-dwelling old subjects using a genome-wide gene expression approach

scientific article published on 28 November 2019

Independent and Combined Effects of Lactitol, Polydextrose, and Bacteroides thetaiotaomicron on Postprandial Metabolism and Body Weight in Rats Fed a High-Fat Diet

scientific article published on 08 June 2016

Inflammation, hippocampal volume, and cognition in schizophrenia: results from the Northern Finland Birth Cohort 1966

scientific article published on 07 May 2020

Inhibition of cytokine secretion from adipocytes by 1,25-dihydroxyvitamin D3 via the NF-κB pathway

scientific article published on 13 July 2012

Inhibitory effects of serum from sepsis patients on epithelial cell migration in vitro: a case control study

scientific article published on 13 January 2017

Injected nanoparticles: the combination of experimental systems to assess cardiovascular adverse effects

scientific article published on 14 February 2014

Inorganic mesoporous particles for controlled α-linolenic acid delivery to stimulate GLP-1 secretion in vitro

scientific article published on 12 September 2019

Interactions of Insoluble Residue from Enzymatic Hydrolysis of Brewer's Spent Grain with Intestinal Microbiota in Mice.

scientific article

Lack of Effects of a Single High-Fat Meal Enriched with Vegetable n-3 or a Combination of Vegetable and Marine n-3 Fatty Acids on Intestinal Peptide Release and Adipokines in Healthy Female Subjects

scientific article published on 31 August 2016

Lack of collagen XVIII leads to lipodystrophy and perturbs hepatic glucose and lipid homeostasis

scientific article published on 25 May 2020

Leukocyte Telomere Length Is Not Reduced in Children and Adults with Cystic Fibrosis but Associates with Clinical Characteristics-A Cross-Sectional Study

scientific article

Life course structural equation model of the effects of prenatal and postnatal growth on adult blood pressure

scientific article published on 8 August 2014

Life-course analysis of a fat mass and obesity-associated (FTO) gene variant and body mass index in the Northern Finland Birth Cohort 1966 using structural equation modeling

scientific article

Longitudinal follow-up of exocrine pancreatic function in pancreatic sufficient cystic fibrosis patients using the fecal elastase-1 test

scientific article published on 01 April 2003

Low level activity thresholds for changes in NMR biomarkers and genes in high risk subjects for Type 2 Diabetes

scientific article published on 18 September 2017

Low-affinity CCK-1 receptors inhibit bombesin-stimulated secretion in rat pancreatic acini--implication of the actin cytoskeleton

scientific journal article

Meals with Similar Fat Content from Different Dairy Products Induce Different Postprandial Triglyceride Responses in Healthy Adults: A Randomized Controlled Cross-Over Trial

article

Measuring Physical Activity in Free-Living Conditions-Comparison of Three Accelerometry-Based Methods

scientific article published on January 2016

Mesoporous silicon (PSi) for sustained peptide delivery: effect of psi microparticle surface chemistry on peptide YY3-36 release.

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Metabolomic changes in fatty liver can be modified by dietary protein and calcium during energy restriction

scientific article published on July 2008

Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis

scientific article

Modern wolves trace their origin to a late Pleistocene expansion from Beringia

article published in 2018

Multi-Day Prolonged Low- to Moderate-Intensity Endurance Exercise Mimics Training Improvements in Metabolic and Oxidative Profiles Without Concurrent Chromosomal Changes in Healthy Adults

scientific article published on 03 September 2019

Nanocarriers and the delivered drug: effect interference due to intravenous administration.

scientific article published on 22 June 2014

Nanostructured porous silicon microparticles enable sustained peptide (Melanotan II) delivery

scientific article published on 20 October 2010

Neuroendocrinological regulation of food intake

scientific article published on 11 April 2008

Neurogenic pulmonary edema in patients with nontraumatic intracerebral hemorrhage: predictors and association with outcome.

scientific article published on 21 February 2013

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Normal pancreatic secretion in children with progressive familial intrahepatic cholestasis type 1

scientific article published on 01 December 2006

Novel delivery systems for improving the clinical use of peptides.

scientific article published on July 2015

Oesophageal defensin expression during Candida infection and reflux disease.

scientific article

Outpatient Antibiotic Use and the Incidence of Acute Appendicitis in Finland: A Nationwide Study from 1990–2008 ⬇️

scientific article published on July 16, 2013

PCSK9 Levels and Metabolic Profiles in Elderly Subjects with Different Glucose Tolerance under Statin Therapy

scientific article

Photocrosslinked poly(ester anhydride)s for peptide delivery: Effect of oligomer hydrophobicity on PYY3-36 delivery

scientific article published on 22 September 2011

Plasma Orexin-A Levels Do Not Undergo Circadian Rhythm in Young Healthy Male Subjects

Plasma alkylresorcinols reflect important whole-grain components of a healthy Nordic diet.

scientific article published on 10 July 2013

Plasma ghrelin levels after two high-carbohydrate meals producing different insulin responses in patients with metabolic syndrome

scientific article

Platelet count, aspirin use, and characteristics of host inflammatory responses in colorectal cancer.

scientific article published on 13 June 2019

Polydextrose changes the gut microbiome and attenuates fasting triglyceride and cholesterol levels in Western diet fed mice.

scientific article

Portal vein cytokines in the early phase of acute experimental oedematous and necrotizing porcine pancreatitis

scientific article published on 07 September 2012

Possible Modifiers of the Association Between Change in Weight Status From Child Through Adult Ages and Later Risk of Type 2 Diabetes

scientific article published on 05 March 2020

Post-weight loss changes in fasting appetite- and energy balance-related hormone concentrations and the effect of the macronutrient content of a weight maintenance diet: a randomised controlled trial

scientific article published on 02 December 2020

Postprandial PYY increase by resistant starch supplementation is independent of net portal appearance of short-chain fatty acids in pigs

scientific article published on 5 October 2017

Potential determinants of vitamin D in Finnish adults: a cross-sectional study from the Northern Finland birth cohort 1966.

scientific article published on 06 March 2017

Preoperative anemia in colorectal cancer: relationships with tumor characteristics, systemic inflammation, and survival

scientific article published on 18 January 2018

Prevalence of Helicobacter pylori infection in patients with cystic fibrosis.

scientific article

Regulation of alternative splicing in human obesity loci

scientific article

Release of Cholecystokinin from Rat Intestinal Mucosal Cells and the Enteroendocrine Cell Line STC-1 in Response to Maleic and Succinic Acid, Fermentation Products of Alcoholic Beverages

scientific article published on 16 January 2020

Retinal arterial blood flow and retinal changes in patients with sepsis: preliminary study using fluorescein angiography

scientific article published on 10 April 2017

Role of Brown and Beige Adipose Tissues in Seasonal Adaptation in the Raccoon Dog ()

scientific article

Seasonal Regulation of Metabolism: The Effect of Wintertime Fasting and Autumnal Fattening on Key Central Regulators of Metabolism and the Metabolic Profile of the Raccoon Dog ()

scientific article

Seasonal variations of acute appendicitis and nonspecific abdominal pain in Finland

scientific article published on April 2014

Serum 25-Hydroxyvitamin D Status and Longitudinal Changes in Weight and Waist Circumference: Influence of Genetic Predisposition to Adiposity.

scientific article

Serum enterolactone concentrations are low in colon but not in rectal cancer patients

scientific article published on 01 August 2019

Serum lipase after secretin stimulation detects mild pancreatic involvement in cystic fibrosis.

scientific article

Stricture of ileo-anal J pouch anastomosis increased the intensity of pouchitis in an experimental rat model ⬇️

scientific article published on October 1, 2012

Structure modification of a milk protein-based model food affects postprandial intestinal peptide release and fullness in healthy young men

scientific article published on 21 June 2011

Systemic inflammation is associated with circulating cell death released keratin 18 fragments in colorectal cancer

scientific article published on 24 June 2020

The Circadian Clock Protein CRY1 Is a Negative Regulator of HIF-1α

The Gut Microbiome in Polycystic Ovary Syndrome and its Association with Metabolic Traits

scientific article published on 17 November 2020

The association between impaired glucose tolerance and soluble CD40 ligand: a 15-year prospective cohort study

scientific article published on 9 January 2016

The effects of cold exposure on leukocytes, hormones and cytokines during acute exercise in humans

scientific article

The effects of group and single housing and automated animal monitoring on urinary corticosterone levels in male C57BL/6 mice.

scientific article published on February 2016

The effects of skin and core tissue cooling on oxygenation of the vastus lateralis muscle during walking and running

scientific article published in November 2016

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors.

scientific article published on 24 October 2006

The relationships between serum cytokine levels and tumor infiltrating immune cells and their clinical significance in colorectal cancer.

scientific article published on 13 February 2016

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

scientific article (publication date: 2013)

The vagal nerves important connectors of the gut and brain for energy balance

scientific article published on 17 December 2020

Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta

scientific article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

scientific article published on 21 December 2018

Understanding the complexity of glycaemic health: systematic bio-psychosocial modelling of fasting glucose in middle-age adults; a DynaHEALTH study

article

Understanding the cumulative risk of maternal prenatal biopsychosocial factors on birth weight: a DynaHEALTH study on two birth cohorts

scientific article published on 24 June 2020

Unresponsive or non-compliant steatorrhea in cystic fibrosis?

scientific article published on 09 June 2006

Vegetarian Diet Alters the Assessment of Exocrine Pancreatic Function With the Use of Fecal Tests

scientific article published in February 2004

Viscosity of oat bran-enriched beverages influences gastrointestinal hormonal responses in healthy humans

scientific article published on 28 January 2009

Vitamin D Deficiency Induces Insulin Resistance and Re-Supplementation Attenuates Hepatic Glucose Output via the PI3K-AKT-FOXO1 Mediated Pathway

scientific article published on 01 January 2020

Vitamin D Levels in Women with Polycystic Ovary Syndrome: A Population-Based Study

scientific article published on 19 November 2019

Vitamin D and adipose tissue-more than storage

scientific article

Vitamin D and cognitive function: A Mendelian randomisation study

scientific article published on 16 October 2017

Vitamin D and living in northern latitudes--an endemic risk area for vitamin D deficiency

scientific article published on June 2008

Vitamin D deficiency at admission is not associated with 90-day mortality in patients with severe sepsis or septic shock: Observational FINNAKI cohort study.

scientific article

Whole grain rye intake, reflected by a biomarker, is associated with favorable blood lipid outcomes in subjects with the metabolic syndrome--a randomized study

scientific article

Wild blueberries (Vaccinium myrtillus) alleviate inflammation and hypertension associated with developing obesity in mice fed with a high-fat diet

scientific article published in 2014

[Comparison of faecal lipase test and faecal elastase-1 test in the assessment of exocrine pancreatic function in cystic fibrosis]

scientific article published on 01 April 2003

[Objective measurement of physical activity in adults]

scientific article published on 01 January 2012

[Regulation of food intake by gastrointestinal peptides]

scientific article published on 01 January 2009

Paulina is supported by:

About Paulina

Help