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List of works by Albert Jeltsch

A Continuous Protein Methyltransferase (G9a) Assay for Enzyme Activity Measurement and Inhibitor Screening

scientific article published on 04 September 2009

A Fast and Accurate Enzyme-Linked Immunosorbent Assay for the Determination of the DNA Cleavage Activity of Restriction Endonucleases

scientific article published on 01 September 1993

A Fluorescence-Based Supramolecular Tandem Assay for Monitoring Lysine Methyltransferase Activity in Homogeneous Solution

scientific article published on 24 February 2012

A dodecapeptide comprising the extended chain-alpha 4 region of the restriction endonuclease EcoRI specifically binds to the EcoRI recognition site

scientific article published on March 1995

A fluorimetric assay for on-line detection of DNA cleavage by restriction endonucleases

scientific article published in June 2002

A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes

scientific article

Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase

scientific article

Activity and specificity of the human SUV39H2 protein lysine methyltransferase

scientific article published on 22 November 2014

Affinity reagents for studying histone modifications & guidelines for their quality control

scientific article

Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm

scientific article published on 12 August 2016

An ATPase-deficient variant of the SNF2 family member HELLS shows altered dynamics at pericentromeric heterochromatin.

scientific article published on 28 March 2015

Analysis of the Substrate Specificity of the SMYD2 Protein Lysine Methyltransferase and Discovery of Novel Non-Histone Substrates

scientific article published on 29 October 2019

Analysis of the substrate specificity of the Dim-5 histone lysine methyltransferase using peptide arrays

scientific article

Anomalous mobility of polymerase chain reaction products after bisulfite treatment of DNA.

scientific article published in October 2004

Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails

scientific article

Application of DNA methyltransferases in targeted DNA methylation

scientific article published on 13 April 2007

Application of dual reading domains as novel reagents in chromatin biology reveals a new H3K9me3 and H3K36me2/3 bivalent chromatin state.

scientific article published on 25 September 2017

Application of histone modification-specific interaction domains as an alternative to antibodies

scientific article published on 9 October 2014

Application of mixed peptide arrays to study combinatorial readout of chromatin modifications

scientific article published on 10 November 2017

Application of modified histone peptide arrays in chromatin research

scientific article published on 02 November 2018

Application of recombinant TAF3 PHD domain instead of anti-H3K4me3 antibody.

scientific article

Approaches and Guidelines for the Identification of Novel Substrates of Protein Lysine Methyltransferases

scientific article

Approaches to enzyme and substrate design of the murine Dnmt3a DNA methyltransferase.

scientific article

Author Correction: Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate

scientific article published on 19 October 2020

Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue.

scientific article

Automated purification of His6-tagged proteins allows exhaustive screening of libraries generated by random mutagenesis

scientific article

Avidin plate assay system for enzymatic characterization of a histone lysine methyltransferase

scientific article published on July 2005

BISMA--fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences

scientific article

Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases

scientific article

Biochemistry and biology of mammalian DNA methyltransferases

scientific article

Biotechnological Applications of MBD Domain Proteins for DNA Methylation Analysis

scientific article published on 05 September 2019

Biotin-avidin microplate assay for the quantitative analysis of enzymatic methylation of DNA by DNA methyltransferases

scientific article published on March 2000

Bisulfite sequencing Data Presentation and Compilation (BDPC) web server--a useful tool for DNA methylation analysis.

scientific article

Burning off DNA Methylation: New Evidence for Oxygen-Dependent DNA Demethylation

article

C5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development.

scientific article

Catalytic mechanism of DNA-(cytosine-C5)-methyltransferases revisited: covalent intermediate formation is not essential for methyl group transfer by the murine Dnmt3a enzyme

scientific article

Changing the DNA recognition specificity of the EcoDam DNA-(adenine-N6)-methyltransferase by directed evolution

scientific article published on 18 September 2009

Changing the target base specificity of the EcoRV DNA methyltransferase by rational de novo protein-design

scientific article published on August 2001

Chimeric DNA methyltransferases target DNA methylation to specific DNA sequences and repress expression of target genes.

scientific article published on 6 December 2006

Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail

scientific article published on 11 March 2010

Chromatin targeting of de novo DNA methyltransferases by the PWWP domain

scientific article published on 3 March 2004

Circular Permutations in the Molecular Evolution of DNA Methyltransferases

scientific article

Clr4 specificity and catalytic activity beyond H3K9 methylation.

scientific article

Complex DNA sequence readout mechanisms of the DNMT3B DNA methyltransferase

scientific article published on 26 October 2020

Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms

scientific article published on 03 July 2020

Conserved motif VIII of murine DNA methyltransferase Dnmt3a is essential for methylation activity

scientific article

Continuous enzymatic assay for histone lysine methyltransferases

scientific article

Cooperative DNA binding and protein/DNA fiber formation increases the activity of the Dnmt3a DNA methyltransferase

scientific article published on 21 August 2014

Correction of aberrant imprinting by allele-specific epigenome editing

scientific article published on 4 November 2015

Crosslinking the EcoRV restriction endonuclease across the DNA-binding site reveals transient intermediates and conformational changes of the enzyme during DNA binding and catalytic turnover

scientific article

Cyclical DNA methylation of a transcriptionally active promoter

scientific article

Cyclin D1 integrates G9a-mediated histone methylation

scientific article published on 04 February 2019

Cytosine methylation of tRNA-Asp by DNMT2 has a role in translation of proteins containing poly-Asp sequences

scientific article published on 09 June 2015

DNA binding specificity of the EcoRV restriction endonuclease is increased by Mg2+ binding to a metal ion binding site distinct from the catalytic center of the enzyme.

scientific article published on May 1995

DNA from Aspergillus flavus contains 5-methylcytosine

scientific article published in November 2001

DNA interaction of the CcrM DNA methyltransferase: a mutational and modeling study

scientific article published on 25 May 2012

DNA methylation analysis by bisulfite conversion, cloning, and sequencing of individual clones

scientific article

DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution

scientific article

DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies

scientific article published on 03 October 2012

DNA of Drosophila melanogaster contains 5-methylcytosine

scientific article

DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation

scientific article published on 24 July 2020

DNMT1-associated DNA methylation changes in cancer

scientific article published in January 2015

De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases

scientific article published in July 2005

Deoxyribonucleic Acid Methyl Transferases 3a and 3b Associate with the Nuclear Orphan Receptor COUP-TFI during Gene Activation

article

Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation

scientific article published on 24 May 2017

Design, synthesis and biological evaluation of 4-amino-N- (4-aminophenyl)benzamide analogues of quinoline-based SGI-1027 as inhibitors of DNA methylation

scientific article published in March 2014

Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays

scientific article published on February 2011

Detection and analysis of enzymatic DNA methylation of oligonucleotide substrates by matrix-assisted laser desorption ionization time-of-flight mass spectrometry

scientific article

Detection and quantitation of the activity of DNA methyltransferases using a biotin/avidin microplate assay.

scientific article

Developing a programmed restriction endonuclease for highly specific DNA cleavage

scientific article

Development of an epigenetic tetracycline sensor system based on DNA methylation

scientific article published on 07 May 2020

Distinct specificities of the <scp>HEMK2</scp> protein methyltransferase in methylation of glutamine and lysine residues

scientific article published in 2024

Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA.

scientific article

Does the Restriction EndonucleaseEcoRV Employ a Two-Metal-Ion Mechanism for DNA Cleavage?†

scientific article published on 01 September 1997

Editorial: Alfred Pingoud (1945-2015).

scientific article published on September 2015

Editorial: Molecular Epigenetics: Connecting Human Biology and Disease with Little Marks

scientific article published on 01 January 2011

Engineering novel restriction endonucleases: principles and applications

scientific article published on July 1996

Engineering of Effector Domains for Targeted DNA Methylation with Reduced Off-Target Effects

scientific article published on 13 January 2020

Enzymes that keep DNA under control: Meeting: DNA enzymes: structures and mechanisms

scientific article published in April 2001

Enzymology of Mammalian DNA Methyltransferases

scientific article published on January 2016

Epigenetics Europe conference. Munich, Germany, 8-9 September 2011.

scientific article

Epigenome Editing: State of the Art, Concepts, and Perspectives

scientific article

Evidence for an evolutionary relationship among type-II restriction endonucleases

scientific article

Evidence for substrate-assisted catalysis in the DNA cleavage of several restriction endonucleases

scientific article published on May 1995

Evolutionary analysis indicates that DNA alkylation damage is a byproduct of cytosine DNA methyltransferase activity.

scientific article published on 19 February 2018

Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns

scientific article published on 24 January 2022

Flexibility of DNA in complex with proteins deduced from the distribution of bending angles observed by scanning force microscopy

scientific article published on August 1998

Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L.

scientific article published on 22 October 2008

Function and disruption of DNA methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation

scientific article published on 16 September 2011

Functional mapping of the EcoRV DNA methyltransferase by random mutagenesis and screening for catalytically inactive mutants

scientific article

Functional roles of conserved amino acid residues in DNA methyltransferases investigated by site-directed mutagenesis of the EcoRV adenine-N6-methyltransferase

scientific article published in July 1998

Genomic imprinting--the struggle of the genders at the molecular level

scientific article

German Human Methylome Project Started

article

Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone

scientific article published on 27 October 2020

H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.

scientific article published on 12 December 2017

H3K36me2/3 Binding and DNA Binding of the DNA Methyltransferase DNMT3A PWWP Domain Both Contribute to its Chromatin Interaction

scientific article published on 18 October 2019

High-throughput purification of polyHis-tagged recombinant fusion proteins.

scientific article

Histone tails regulate DNA methylation by allosterically activating de novo methyltransferase.

scientific article

Horizontal gene transfer contributes to the wide distribution and evolution of type II restriction-modification systems

scientific article

How does a DNA interacting enzyme change its specificity during molecular evolution? A site-directed mutagenesis study at the DNA binding site of the DNA-(adenine-N6)-methyltransferase EcoRV.

scientific article

Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism

scientific journal article

Identification of ICAD-derived peptides capable of inhibiting caspase-activated DNase

scientific article

Identification of novel inhibitors of DNA methylation by screening of a chemical library.

scientific article

Identification of protein lysine methylation readers with a yeast three-hybrid approach.

scientific article

Identification, cloning and heterologous expression of active [NiFe]-hydrogenase 2 from Citrobacter sp. SG in Escherichia coli

scientific article

Impact of 7,8-dihydro-8-oxoguanine on methylation of the CpG site by Dnmt3a

scientific article published in February 2009

Intra- vs intersubunit communication in the homodimeric restriction enzyme EcoRV: Thr 37 and Lys 38 involved in indirect readout are only important for the catalytic activity of their own subunit

scientific article

Introduction of asymmetry in the naturally symmetric restriction endonuclease EcoRV to investigate intersubunit communication in the homodimeric protein

scientific article published on June 1996

Investigation of H2AX methylation by the SUV39H2 protein lysine methyltransferase

scientific article

Investigation of the C-terminal domain of the bacterial DNA-(adenine N6)-methyltransferase CcrM.

scientific article

Investigation of the methylation of Numb by the SET8 protein lysine methyltransferase

scientific article published on 22 September 2015

Kinetic characterization of linear diffusion of the restriction endonuclease EcoRV on DNA.

scientific article

Kinetics of methylation and binding of DNA by the EcoRV adenine-N6 methyltransferase

scientific article

Label-free measurement of histone lysine methyltransferases activity by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

scientific article

Level of tissue differentiation influences the activation of a heat-inducible flower-specific system for genetic containment in poplar (Populus tremula L.).

scientific article published on 31 October 2015

Linear diffusion of the restriction endonuclease EcoRV on DNA is essential for the in vivo function of the enzyme

scientific article

Maintenance of species identity and controlling speciation of bacteria: a new function for restriction/modification systems? ⬇️

scientific article published on October 23, 2003

Mapping of protein-protein interaction sites by the 'absence of interference' approach.

scientific article

Mapping the tRNA binding site on the surface of human DNMT2 methyltransferase

scientific article published on 23 May 2012

Mechanism and biological role of Dnmt2 in Nucleic Acid Methylation.

scientific article published on 27 May 2016

Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy

scientific article

Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L.

scientific article published on 24 January 2005

Mechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges

scientific article published on January 2016

Mechanistic Insights into the Allosteric Regulation of the Clr4 Protein Lysine Methyltransferase by Autoinhibition and Automethylation

scientific article published on 22 November 2020

Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase

scientific article published on 26 May 2012

Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine

scientific article

Methods for determining activity and specificity of DNA binding and DNA cleavage by class II restriction endonucleases

scientific article

Methylation of recombinant mononucleosomes by DNMT3A demonstrates efficient linker DNA methylation and a role of H3K36me3

scientific article published on 02 March 2022

Methylation sensitivity of restriction enzymes interacting with GATC sites

scientific article published on 01 May 2003

Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites

scientific article published on 21 September 2017

Molecular Processes Connecting DNA Methylation Patterns with DNA Methyltransferases and Histone Modifications in Mammalian Genomes

article

Molecular Processes Connecting DNA Methylation Patterns with DNA Methyltransferases and Histone Modifications in Mammalian Genomes

scientific article published on 21 May 2019

Molecular enzymology of mammalian DNA methyltransferases

scientific journal article

Molecular enzymology of the EcoRV DNA-(Adenine-N (6))-methyltransferase: kinetics of DNA binding and bending, kinetic mechanism and linear diffusion of the enzyme on DNA.

scientific article published on October 2000

Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases

scientific journal article

Multimerization of the dnmt3a DNA methyltransferase and its functional implications

scientific article published on January 2013

Mutational Analysis of the Function of Gln115 in the EcoRI Restriction Endonuclease, a Critical Amino Acid for Recognition of the Inner Thymidine Residue in the Sequence -GAATTC- and for Coupling Specific DNA Binding to Catalysis

article

Mutational analysis of target base flipping by the EcoRV adenine-N6 DNA methyltransferase

scientific article

Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase.

scientific article published on 30 January 2006

Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L

scientific article

Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns

scientific article published on 01 December 2019

New clustering module in BDPC bisulfite sequencing data presentation and compilation web application for DNA methylation analyses

scientific article

New concepts in DNA methylation

scientific article

Non-imprinted allele-specific DNA methylation on human autosomes.

scientific article

Non-radioactive protein lysine methyltransferase microplate assay based on reading domains

scientific article published on 13 May 2013

Nucleosome stability measured in situ by automated quantitative imaging.

scientific article published on 6 October 2017

Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules: heterochromatic localization and role of Dnmt3L.

scientific article published on 12 May 2011

On the Divalent Metal Ion Dependence of DNA Cleavage by Restriction Endonucleases of the EcoRI Family

scientific article published on 13 August 2009

On the Evolutionary Origin of Eukaryotic DNA Methyltransferases and Dnmt2 ⬇️

scientific article published on November 30, 2011

On the Substrate Specificity of DNA Methyltransferases

scientific article published in Journal of Biological Chemistry

On the enzymatic properties of Dnmt1: specificity, processivity, mechanism of linear diffusion and allosteric regulation of the enzyme

scientific article published on 05 April 2006

On the possibilities and limitations of rational protein design to expand the specificity of restriction enzymes: a case study employing EcoRV as the target

scientific article published on 01 April 2000

Oxygen, epigenetic signaling, and the evolution of early life

scientific article published on 28 February 2013

PCR-based random mutagenesis method using spiked oligonucleotides to randomize selected parts of a gene without any wild-type background

article

PWWP-DOMAIN INTERACTOR OF POLYCOMBS11 interacts with Polycomb-group proteins and histones and regulates Arabidopsis flowering and development.

scientific article published on 12 January 2018

Pausing of the restriction endonuclease EcoRI during linear diffusion on DNA.

scientific article published on August 1994

Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation

scientific article

Phosphorylation of serine-515 activates the Mammalian maintenance methyltransferase Dnmt1.

scientific article

Phylogeny of Methylomes

scientific article published in Science

Pmt1, a Dnmt2 homolog in Schizosaccharomyces pombe, mediates tRNA methylation in response to nutrient signaling.

scientific article published on 15 October 2012

Probing the DNA interface of the EcoRV DNA-(adenine-N6)-methyltransferase by site-directed mutagenesis, fluorescence spectroscopy, and UV cross-linking

scientific article

Probing the indirect readout of the restriction enzyme EcoRV. Mutational analysis of contacts to the DNA backbone

scientific article

Profound Flanking Sequence Preference of Dnmt3a and Dnmt3b Mammalian DNA Methyltransferases Shape the Human Epigenome

scientific article published on 29 March 2005

Protein engineering of the restriction endonuclease EcoRV . Structure-guided design of enzyme variants that recognize the base pairs flanking the recognition site

scientific article published on 01 November 1998

Protein engineering of the restriction endonuclease EcoRV: replacement of an amino acid residue in the DNA binding site leads to an altered selectivity towards unmodified and modified substrates

scientific article published on September 1994

Protein lysine methyltransferase G9a acts on non-histone targets

scientific article published on 27 April 2008

Putting the pieces together: histone H2B ubiquitylation directly stimulates histone H3K79 methylation

scientific article published in September 2008

Quality of histone modification antibodies undermines chromatin biology research

scientific article

Rapid synthesis of new DNMT inhibitors derivatives of procainamide

scientific article

Reading and writing DNA methylation

scientific article published on 01 October 2008

Recognition and cleavage of DNA by type-II restriction endonucleases

scientific article

Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a.

scientific article

Reversible inactivation of the CG specific SssI DNA (cytosine-C5)-methyltransferase with a photocleavable protecting group

scientific article published in January 2007

Role of somatic cancer mutations in human protein lysine methyltransferases

scientific article

Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate

scientific article published on 16 September 2020

Silencing of Gene Expression by Targeted DNA Methylation: Concepts and Approaches ⬇️

scientific article published on January 1, 2010

Site-directed mutagenesis by polymerase chain reaction

scientific article published on 01 January 2002

Site-directed mutagenesis in the catalytic center of the restriction endonuclease EcoRI.

scientific article

Somatic cancer mutations in the DNMT2 tRNA methyltransferase alter its catalytic properties

scientific article published on 05 March 2015

Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex

scientific article

Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme

scientific article published on 28 March 2015

Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

scientific article published in 2024

Specificity Analysis of Histone Modification-Specific Antibodies or Reading Domains on Histone Peptide Arrays

scientific article published in January 2015

Specificity Analysis-Based Identification of New Methylation Targets of the SET7/9 Protein Lysine Methyltransferase

article

Specificity analysis of protein lysine methyltransferases using SPOT peptide arrays

scientific article

Specificity of DNA binding and methylation by the M.FokI DNA methyltransferase

scientific article published on July 2000

Specificity of DNA triple helix formation analyzed by a FRET assay

scientific article

Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain.

scientific article published in May 2012

Specificity of protein lysine methyltransferases and methods for detection of lysine methylation of non-histone proteins

scientific article published on 20 October 2008

Specificity of the SUV4-20H1 and SUV4-20H2 protein lysine methyltransferases and methylation of novel substrates

scientific article published on 19 April 2016

Stopped-flow and mutational analysis of base flipping by the Escherichia coli Dam DNA-(adenine-N6)-methyltransferase

scientific article

Structural and biochemical characterization of a new Mg(2+) binding site near Tyr94 in the restriction endonuclease PvuII

scientific article

Structural and biochemical insight into the mechanism of dual CpG site binding and methylation by the DNMT3A DNA methyltransferase

scientific article published on 01 August 2021

Structure and function of mammalian DNA methyltransferases.

scientific article

Structure and function of type II restriction endonucleases

scientific article

Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase

scientific article published on 28 February 2006

Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

scientific article

Structure prediction of the EcoRV DNA methyltransferase based on mutant profiling, secondary structure analysis, comparison with known structures of methyltransferases and isolation of catalytically inactive single mutants

article

Substrate Specificity of the HEMK2 Protein Glutamine Methyltransferase and Identification of Novel Substrates

scientific article published on 21 January 2016

Substrate specificity analysis and novel substrates of the protein lysine methyltransferase NSD1.

scientific article

Substrate-assisted catalysis in the cleavage of DNA by the EcoRI and EcoRV restriction enzymes

scientific article published on September 1993

Synthesis and evaluation of analogues of N-phthaloyl-l-tryptophan (RG108) as inhibitors of DNA methyltransferase 1.

scientific article published on 9 January 2014

Target recognition, RNA methylation activity and transcriptional regulation of the Dictyostelium discoideum Dnmt2-homologue (DnmA)

scientific article

Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained.

scientific article

Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity

scientific article published on 4 December 2012

Targeted methylation of the epithelial cell adhesion molecule (EpCAM) promoter to silence its expression in ovarian cancer cells

scientific article

Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain

scientific article published on 13 February 2014

The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9

scientific article

The Caulobacter crescentus DNA-(adenine-N6)-methyltransferase CcrM methylates DNA in a distributive manner.

scientific article published on 16 September 2011

The DNMT3A R882H mutant displays altered flanking sequence preferences

scientific article published on 6 March 2018

The DNMT3A R882H mutation does not cause dominant negative effects in purified mixed DNMT3A/R882H complexes

scientific article published in Scientific Reports

The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites

scientific article

The Dnmt2 RNA methyltransferase homolog of Geobacter sulfurreducens specifically methylates tRNA-Glu

scientific article

The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation

scientific article

The Escherichia coli dam DNA methyltransferase modifies DNA in a highly processive reaction

scientific article

The Flavobacterium okeanokoites adenine-N6-specific DNA-methyltransferase M.FokI is a tandem enzyme of two independent domains with very different kinetic properties.

scientific article

The M.EcoRV DNA-(adenine N6)-methyltransferase uses DNA bending for recognition of an expanded EcoDam recognition site.

scientific article published on 31 October 2007

The Mechanism of DNA Cleavage by the Type II. Restriction Enzyme EcoRV: Asp36 Is Not Directly Involved in DNA Cleavage but Serves to Couple Indirect. Readout to Catalysis

scientific article published on 01 April 1998

The RNA methyltransferase Dnmt2 methylates DNA in the structural context of a tRNA.

scientific article

The SET8 H4K20 protein lysine methyltransferase has a long recognition sequence covering seven amino acid residues.

scientific article published on 11 May 2012

The SUV39H1 Protein Lysine Methyltransferase Methylates Chromatin Proteins Involved in Heterochromatin Formation and VDJ Recombination

scientific article published on 7 February 2017

The Tudor domain of the PHD finger protein 1 is a dual reader of lysine trimethylation at lysine 36 of histone H3 and lysine 27 of histone variant H3t.

scientific article

The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism

scientific article published on 24 December 2013

The ankyrin repeat domain of Huntingtin interacting protein 14 contains a surface aromatic cage, a potential site for methyl-lysine binding

scientific article

The application of next generation sequencing in DNA methylation analysis

scientific article published on 04 June 2010

The cytosine N4-methyltransferase M.PvuII also modifies adenine residues

scientific article published in April 2001

The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates

scientific article published in Nature Communications

The human Dnmt2 has residual DNA-(cytosine-C5) methyltransferase activity.

scientific article

The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols.

scientific article

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

scientific article published on 09 February 2021

Towards the design of rare cutting restriction endonucleases: using directed evolution to generate variants of EcoRV differing in their substrate specificity by two orders of magnitude ⬇️

article by T Lanio et al published October 1998 in Journal of Molecular Biology

Transition from EcoDam to T4Dam DNA recognition mechanism without loss of activity and specificity

scientific article published in October 2009

Transition from nonspecific to specific DNA interactions along the substrate-recognition pathway of dam methyltransferase.

scientific article

Two alternative conformations of S-adenosyl-L-homocysteine bound to Escherichia coli DNA adenine methyltransferase and the implication of conformational changes in regulating the catalytic cycle

scientific article

Two substrates are better than one: dual specificities for Dnmt2 methyltransferases

scientific article

Using the fluorescence decay of 2-aminopurine to investigate conformational change in the recognition sequence of the EcoRV DNA-(adenine-N6)-methyltransferase on enzyme binding

scientific article published on 10 September 2011

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