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List of works by Guilherme Suarez-Kurtz

4th ESPT Conference: pharmacogenomics and personalized medicine - research progress and clinical implementation

scientific article published on 01 October 2019

A background subtraction approach for determination of endogenous cortisol and 6β-hydroxycortisol in urine by UPLC-MS/MS with application in a within-day variability study in HIV-infected pregnant women

scientific article published on 19 March 2020

A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library

scientific article

A new model for the population pharmacokinetics of didanosine in healthy subjects

A phase I study of mTOR inhibitor everolimus in association with cisplatin and radiotherapy for the treatment of locally advanced cervix cancer: PHOENIX I.

scientific article

A rapid and sensitive method for simultaneous determination of lamivudine and zidovudine in human serum by on-line solid-phase extraction coupled to liquid chromatography/tandem mass spectrometry detection

scientific article published on January 2004

ABCB1 polymorphisms and the concentrations of lopinavir and ritonavir in blood, semen and saliva of HIV-infected men under antiretroviral therapy.

scientific article published in February 2009

Accuracy of NAT2 SNP genotyping panels to infer acetylator phenotypes in African, Asian, Amerindian and admixed populations

article

Aminoglycoside-induced suppression of CYP2C19*3 premature stop codon

scientific article published on 01 November 2011

Antagonism of the myotoxic effects of Bothrops jararacussu venom and bothropstoxin by polyanions.

scientific article published in March 1993

Application of the F(ST) statistics to explore pharmacogenomic diversity in the Brazilian population

scientific article

Association of genetic variants with self-assessed color categories in Brazilians

scientific article

Association of the UGT1A1-53(TA)n polymorphism with L-thyroxine doses required for thyrotropin suppression in patients with differentiated thyroid cancer

scientific article published on 01 June 2011

BRCA1 recruitment to damaged DNA sites is dependent on CDK9.

scientific article

Basic polyaminoacids and protamine stimulate enzyme release from frog muscles

Birefringence signals and calcium transients in skeletal muscle

scientific article published in Nature

Bovine serum albumin potentiates caffeine- or ATP-induced tension in human skinned skeletal muscle fibers

scientific article published on 01 May 1997

CYP2A6 genetic polymorphisms and correlation with smoking status in Brazilians.

scientific article published in January 2005

CYP2C9 genotypes and the pharmacokinetics of tenoxicam in Brazilians

scientific article

CYP2D6 activity and the risk of recurrence of Plasmodium vivax malaria in the Brazilian Amazon: a prospective cohort study

scientific article published in February 2018

CYP3A5 genotype has no impact on plasma trough concentrations of lopinavir and ritonavir in HIV-infected subjects.

scientific article published on 20 February 2008

CYP3A5 genotype, but not CYP3A4*1b, CYP3A4*22, or hematocrit, predicts tacrolimus dose requirements in Brazilian renal transplant patients.

scientific article published on 2 April 2013

Ca2+-entry blockade by CAF603, a carotane sesquiterpene isolated from Trichoderma virens

scientific article published on 01 September 1997

Characterization of LGALS3 (galectin-3) as a player in DNA damage response.

scientific article published on 22 April 2014

Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update

scientific article published on 20 January 2019

Clinically Actionable Genotypes Among Brazilians

article

Conference Report: First Pharmacogenetics and Precision Medicine Conference in Africa (April 7-9, 2016, Cape Town, South Africa).

scientific article published on September 2016

Conference Scene: Latin American Pharmacogenomics and Personalized Medicine Conference ⬇️

scientific article published on October 1, 2012

Conference report: pharmacogenomics in special populations at WCP2018

scientific article published on 24 January 2019

Currents carried by sodium ions through transient calcium channels in clonal GH3 pituitary cells.

scientific article published in October 1987

DNA repair genes PAXIP1 and TP53BP1 expression is associated with breast cancer prognosis

scientific article published on 5 May 2017

Demographic history and human genetic diversity: pharmacogenomic implications.

scientific article

Detection of CYP2C9*5 in a white Brazilian subject

scientific article published in June 2005

Determination of didanosine in human serum by on-line solid-phase extraction coupled to high-performance liquid chromatography with electrospray ionization tandem mass spectrometric detection: application to a bioequivalence study

scientific article published in April 2003

Determination of lopinavir and ritonavir in blood plasma, seminal plasma, saliva and plasma ultra-filtrate by liquid chromatography/tandem mass spectrometry detection.

scientific article published in January 2008

Determination of stavudine in human serum by on-line solid-phase extraction coupled to high-performance liquid chromatography with electrospray ionization tandem mass spectrometry: application to a bioequivalence study

scientific article published in January 2003

Development and validation of limited-sampling strategies for predicting amoxicillin pharmacokinetic and pharmacodynamic parameters

scientific article

Development of a rapid and specific assay for detection of busulfan in human plasma by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry

scientific article published in January 2005

Differential effects of predictors of warfarin dose according to race/color categories in the admixed Brazilian population

article

Dissociation of action potentials from contraction in single crab muscle fibers ⬇️

scientific article published on June 1, 1979

Distribution and linkage disequilibrium of the enhancer SNP rs5758550 among Latin American populations: influence of continental ancestry

scientific article published on 16 March 2020

Distribution of CYP2C Polymorphisms in an Amerindian Population of Brazil

article

Distribution of CYP2D6 alleles and phenotypes in the Brazilian population

scientific article

Distribution of the GNB3 825C>T polymorphism among Brazilians: impact of population structure

article

Distribution ofABCB1polymorphisms among Brazilians: impact of population admixture

article

Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals

scientific article published on 17 February 2019

Effect of UGT1A1, UGT1A3, DIO1 and DIO2 polymorphisms on L-thyroxine doses required for TSH suppression in patients with differentiated thyroid cancer

scientific article

Effect of bovine serum albumin on the calcium release channel of sarcoplasmic reticulum from rabbit skeletal muscle.

scientific article published on July 1997

Effect of local anesthetics on radiocalcium binding in nerve ⬇️

scientific article published on April 1, 1970

Effects of NS1608, a BK(Ca) channel agonist, on the contractility of guinea-pig urinary bladder in vitro

scientific article published in March 2005

Effects of neomycin on calcium channel currents in clonal GH3 pituitary cells.

scientific article

Effects of phenytoin on the ventricular tachyarrhythmias of chronic Chagas' disease

Effects of verapamil on excitation-contraction coupling in single crab muscle fibers

scientific article published on April 25, 1977

Estimating the genetic component (RGC) in pharmacokinetic variability of the antiretroviral didanosine among healthy Brazilians

scientific article

Ether à go-go potassium channel expression in soft tissue sarcoma patients

scientific article

Ethnic differences in drug therapy: a pharmacogenomics perspective

scientific article published on 01 May 2008

Excitation-contraction coupling: role of K-activation within the transverse tubular system.

scientific article published on February 1983

Exploring the distribution of genetic markers of pharmacogenomics relevance in Brazilian and Mexican populations

scientific article

Exploring warfarin pharmacogenomics with the extreme-discordant-phenotype methodology: impact of FVII polymorphisms on stable anticoagulation with warfarin.

scientific article published on 23 April 2009

Functional effects of uridine triphosphate on human skinned skeletal muscle fibers

scientific article published on 01 February 1998

Genetic Factors Influencing Warfarin Dose in Black-African Patients: A Systematic Review and Meta-Analysis

scientific article published on 23 December 2019

Genome-wide association study of warfarin maintenance dose in a Brazilian sample

scientific article

Global pharmacogenomics: Impact of population diversity on the distribution of polymorphisms in the CYP2C cluster among Brazilians.

scientific article

Global pharmacogenomics: distribution of CYP3A5 polymorphisms and phenotypes in the Brazilian population

scientific article published on 10 January 2014

High prevalence of the GSTM3*A/B polymorphism in sub-Sarahan African populations

scientific article published on 11 June 2010

Hormonal status affects plasma exposure of tamoxifen and its main metabolites in tamoxifen-treated breast cancer patients

scientific article published on 19 December 2019

INFLUENCE OF PHARMACOGENETIC POLYMORPHISMS AND DEMOGRAPHIC VARIABLES ON METFORMIN PHARMACOKINETICS IN AN ADMIXED BRAZILIAN COHORT.

scientific article published on 20 January 2018

Impact of CYP2C9*3/*3 genotype on the pharmacokinetics and pharmacodynamics of oxicam NSAIDs

scientific article published on 01 August 2014

Impact of CYP2C93/3 genotype on the pharmacokinetics and pharmacodynamics of piroxicam

scientific article published on 01 November 2006

Impact of CYP4F2 rs2108622 on the stable warfarin dose in an admixed patient cohort.

scientific article published on 24 February 2010

Impact of Plasmodium vivax malaria and antimalarial treatment on cytochrome P450 activity in Brazilian patients

scientific article published on 30 September 2020

Impact of amino acid substitutions at secondary structures in the BRCT domains of the tumor suppressor BRCA1: Implications for clinical annotation

scientific article published on 14 February 2019

Impact of population admixture on the distribution of theCYP3A5*3polymorphism

scientific article published on 01 October 2007

Impact of population diversity on the prediction of 7-SNP NAT2 phenotypes using the tagSNP rs1495741 or paired SNPs

scientific article

Impact of the CYP4F2 p.V433M polymorphism on coumarin dose requirement: systematic review and meta-analysis

scientific article

Impact of visceral leishmaniasis and curative chemotherapy on cytochrome P450 activity in Brazilian patients

scientific article

Implementation of a pharmacogenomic program in a Brazilian Public Institution

scientific article published on 07 May 2020

Influence of CYP2C9 genotypes on the pharmacokinetics and pharmacodynamics of piroxicam.

scientific article published in October 2005

Influence of Genomic Ancestry on the Distribution of SLCO1B1, SLCO1B3 and ABCB1 Gene Polymorphisms among Brazilians

article

Influence of the CYP2C9*3 allele on the pharmacological interaction between warfarin and simvastatin

scientific article published on 01 November 2012

Inhibition by hypertonic solutions of Ca-dependent electrogenesis in single crab muscle fibers ⬇️

scientific article published on October 1, 1977

Inhibition of membrane calcium activation by neomycin and streptomycin in crab muscle fibers ⬇️

scientific article published on January 1, 1974

Inhibition of the myotoxic activities of three African Bitis venoms (B. rhinoceros, B. arietans and B. nasicornis) by a polyvalent antivenom

scientific article published on 24 October 2009

Inhibition of the myotoxic and hemorrhagic activities of crotalid venoms by Eclipta prostrata (Asteraceae) extracts and constituents

scientific article published on 01 May 1994

L-thyroxine doses required for TSH suppression in patients with differentiated thyroid cancer: Effect of a novel UGT1 marker, rs11563250A > G.

scientific article published on 16 August 2016

Letter to the Editor: Combined CYP2C9, VKORC1 and CYP4F2 frequencies among Amerindians, Mozambicans and Brazilians

article

Limited Penetration of Lopinavir and Ritonavir in the Genital Tract of Men Infected with HIV-1 in Brazil

article

Limited Sampling Modeling for Estimation of Phenotypic Metrics for CYP Enzymes and the ABCB1 Transporter Using a Cocktail Approach

scientific article published on 14 February 2020

Limited sampling approach.

scientific article published in June 2001

Limited sampling strategy for determining metformin area under the plasma concentration-time curve

scientific article published on 20 June 2016

Limited-sampling strategy models for estimating the area under the plasma concentration-time curve for amlodipine

article

Limited-sampling strategy models for estimating the pharmacokinetic parameters of 4-methylaminoantipyrine, an active metabolite of dipyrone

scientific article published in November 2001

Linkage disequilibrium between the CYP2C19*17 and CYP2C8*2 alleles in populations of African descent

article

Malaria downmodulates mRNA expression and catalytic activities of CYP1A2, 2E1 and 3A11 in mouse liver.

scientific article published on 6 June 2009

Modulation of the Ca(2+) release channel of sarcoplasmic reticulum by amiloride analogs.

scientific article published in March 2000

NUDT15 Polymorphism in Native American Populations of Brazil

scientific article published on 21 March 2019

Network of Interactions between ZIKA Virus Non-Structural Proteins and Human Host Proteins

scientific article published on 08 January 2020

Neutralization of lethal and myotoxic activities of South American rattlesnake venom by extracts and constituents of the plant Eclipta prostrata (Asteraceae)

article

Pharmacogene Variation Consortium Gene Introduction: NUDT15

article

Pharmacogenetic testing in oncology: a Brazilian perspective

article

Pharmacogenetics in the Brazilian Population ⬇️

scientific article published on October 4, 2010

Pharmacogenetics of calcineurin inhibitors in Brazilian renal transplant patients

scientific article published on 01 August 2011

Pharmacogenetics of coumarin anticoagulants in Brazilians

scientific article

Pharmacogenetics of warfarin: development of a dosing algorithm for brazilian patients

scientific article published on 27 August 2008

Pharmacogenomic Diversity among Brazilians: Influence of Ancestry, Self-Reported Color, and Geographical Origin

scientific article

Pharmacogenomic implications of population admixture: Brazil as a model case

scientific article published on February 2014

Pharmacogenomics and the genetic diversity of the Brazilian population

scientific article

Pharmacogenomics in Brazil

article

Pharmacogenomics in admixed populations

scientific article

Pharmacogenomics in admixed populations: the Brazilian pharmacogenetics/pharmacogenomics network—REFARGEN

article

Pharmacogenomics in the Americas: the impact of genetic admixture.

scientific article published on December 2006

Pharmacogenomics of thiopurines: distribution of TPMT and NUDT15 polymorphisms in the Brazilian Amazon

scientific article published on 22 May 2020

Pharmacogenomics of warfarin in populations of African descent

scientific article published on February 2013

Pharmacogenomics research and clinical implementation in Brazil

scientific article published on 24 January 2019

Pharmacogeomic implications of population diversity in Latin America: TPMT and NUDT15 polymorphisms and thiopurine dosing

scientific article published on 01 January 2020

Population Diversity in Pharmacogenetics: A Latin American Perspective

scientific article published on 19 March 2018

Population diversity and the performance of warfarin dosing algorithms ⬇️

scientific article published on September 1, 2011

Population impact of pharmacogenetic tests in admixed populations across the Americas

scientific article published on 27 October 2020

Post-marketing assessment of generic tamoxifen in Brazilian breast cancer patients

scientific article published on 23 November 2019

Potassium channels in T lymphocytes: therapeutic targets for autoimmune disorders?

scientific article published in January 2004

Prednisolone: limited sampling strategies for estimating pharmacokinetic parameters

scientific article published in February 2004

Probing structure-function relationships in missense variants in the carboxy-terminal region of BRCA1

scientific article (publication date: 2014)

Race and ancestry in biomedical research: exploring the challenges

scientific article

Relative contribution of VKORC1, CYP2C9, and INR response to warfarin stable dose.

scientific article published in April 2009

Release of sarcoplasmic enzymes from skeletal muscle by Bothrops jararacussu venom: antagonism by heparin and by the serum of South American marsupials

scientific article published on 01 January 1988

Risk assessment and communication tools for genotype associations with multifactorial phenotypes: the concept of "edge effect" and cultivating an ethical bridge between omics innovations and society

scientific article

Selective, direct activation of high-conductance, calcium-activated potassium channels causes smooth muscle relaxation

scientific article published on 12 January 2012

Self-reported skin color, genomic ancestry and the distribution of GST polymorphisms

scientific article published on 01 September 2007

Shaker-type Kv1 channel blockers increase the peristaltic activity of guinea-pig ileum by stimulating acetylcholine and tachykinins release by the enteric nervous system. ⬇️

scientific article

Single nucleotide polymorphism coverage and inference of N-acetyltransferase-2 acetylator phenotypes in wordwide population groups

scientific article

Species differences in the influence of chlorothiazide on curarization.

scientific article

Study of membrane potential in T lymphocytes subpopulations using flow cytometry

scientific article

The Implications of Population Admixture in Race-based Drug Prescription

scientific article published on 01 March 2008

The Role of PALB2 in the DNA Damage Response and Cancer Predisposition.

scientific article published on 31 August 2017

The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected

scientific article published on 16 February 2011

The impact of SLCO1B1 polymorphisms on the plasma concentration of lopinavir and ritonavir in HIV-infected men.

scientific article published on January 2010

Thiopurine methyltransferase phenotypes and genotypes in Brazilians

article

Uncovering association networks through an eQTL analysis involving human miRNAs and lincRNAs ⬇️

scientific article published in Scientific Reports

Uridine triphosphate-sensitive pathway of Ca2+ release from the sarcoplasmic reticulum of rat skeletal muscle fibers

article

VKORC1 polymorphisms in Amerindian populations of Brazil

scientific article published in November 2008

VKORC1 polymorphisms in Brazilians: comparison with the Portuguese and Portuguese-speaking Africans and pharmacogenetic implications

scientific article published on September 2010

Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups

scientific article

Worldwide allele frequency distribution of four polymorphisms associated with warfarin dose requirements.

scientific article published on 17 June 2010

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