List of works - Marie-Laure Yaspo

5-Fluorouracil treatment induces characteristic T>G mutations in human cancer

scientific article published on 08 October 2019

A gene expression map of human chromosome 21 orthologues in the mouse

scientific article

A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome

scientific article (publication date: 15 August 2008)

A high-resolution anatomical atlas of the transcriptome in the mouse embryo

scientific article

A simple strand-specific RNA-Seq library preparation protocol combining the Illumina TruSeq RNA and the dUTP methods ⬇️

scientific article published on May 15, 2012

ARH-seq: identification of differential splicing in RNA-seq data

scientific article

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

scientific article published on 27 January 2016

An efficient and economic enhancer mix for PCR

article

An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

scientific article

Analysis of the DNA-binding profile and function of TALE homeoproteins reveals their specialization and specific interactions with Hox genes/proteins.

scientific article published on 18 April 2013

Applicability of liquid biopsies to represent the mutational profile of tumor tissue from different cancer entities

scientific article published on 06 July 2021

Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules

scientific article

BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence

scientific article

Cancer Precision Medicine: Why More Is More and DNA Is Not Enough

scientific article published on 09 June 2017

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

scientific article

Cell type specific novel lncRNAs and circRNAs in the BLUEPRINT haematopoietic transcriptomes atlas

scientific article published on 23 July 2020

ChIP-Seq and RNA-Seq analyses identify components of the Wnt and Fgf signaling pathways as Prep1 target genes in mouse embryonic stem cells

scientific article published on 13 April 2015

Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes

scientific article published on 01 January 2019

Combined HAT/EZH2 modulation leads to cancer-selective cell death.

scientific article published on 22 May 2018

Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains

scientific article

Comparative analysis of neutrophil and monocyte epigenomes

Construction and analysis of a human-chimpanzee comparative clone map.

scientific article

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

scientific article

Dissecting the genomic complexity underlying medulloblastoma

scientific article

Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils

scientific article published on 01 September 2018

Endocytosis-mediated replenishment of amino acids favors cancer cell proliferation and survival in chromophobe renal cell carcinoma

scientific article published on 28 October 2020

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

scientific article

Epigenomic and functional dynamics of human bone marrow myeloid differentiation to mature blood neutrophils

Erratum to: 'The direction of cross affects obesity after puberty in male but not female offspring'.

scientific article published on 30 November 2015

Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters

scientific article

Gene expression variation in Down's syndrome mice allows prioritization of candidate genes

scientific article published in January 2007

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells

scientific article

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

scientific article

Human Lineage-Specific Transcriptional Regulation through GA-Binding Protein Transcription Factor Alpha (GABPa).

scientific article published on 26 January 2016

Hypermutation of the inactive X chromosome is a frequent event in cancer

scientific article published on 17 October 2013

ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing.

scientific article

Impact of congenital cytomegalovirus infection on transcriptomes from archived dried blood spots in relation to long-term clinical outcome

scientific article published in PLoS ONE

Impaired Planar Germ Cell Division in the Testis, Caused by Dissociation of RHAMM from the Spindle, Results in Hypofertility and Seminoma

scientific article published on 19 August 2016

Influence of RNA extraction methods and library selection schemes on RNA-seq data

scientific article

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer

scientific article

Mass Cytometry-A Tool for the Curious: Networking in Berlin

scientific article published on 16 April 2020

Matrin 3 Binds and Stabilizes mRNA ⬇️

scientific article published on August 17, 2011

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome

scientific article published on 01 September 2019

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome

scientific article published on 11 July 2019

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

scientific article published on 05 April 2016

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

scientific article

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

scientific article published on 01 December 2018

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

scientific article published on 10 February 2017

Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia.

scientific article

Network and systems biology: essential steps in virtualising drug discovery and development

scientific article published on 08 August 2015

Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation

scientific article published on 13 May 2014

Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments

scientific article

Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells

scientific article

Rational therapy with vigabatrin and a ketogenic diet in a patient with GAD1 deficiency

scientific article published on 04 November 2020

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

scientific article

Regulation of the MID1 protein function is fine-tuned by a complex pattern of alternative splicing

scientific article

Screening of human gene promoter activities using transfected-cell arrays

scientific article published on January 2010

Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes

scientific article published on 27 April 2018

Support of a molecular tumour board by an evidence-based decision management system for precision oncology

scientific article published on 23 January 2020

The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle

scientific article

The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability

scientific article published on 14 November 2019

The direction of cross affects [corrected] obesity after puberty in male but not female offspring

scientific article published on 6 November 2015

The hematopoietic stem cell marker VNN2 is associated with chemoresistance in pediatric B-cell precursor ALL

scientific article published on 01 September 2020

The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells

scientific article

The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

scientific article published on 21 May 2018

The whole-genome landscape of medulloblastoma subtypes

scientific article published in July 2017

Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome

scientific article published on July 2004

List of works by Marie-Laure Yaspo

5-Fluorouracil treatment induces characteristic T>G mutations in human cancer

A gene expression map of human chromosome 21 orthologues in the mouse

A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome

A high-resolution anatomical atlas of the transcriptome in the mouse embryo

A simple strand-specific RNA-Seq library preparation protocol combining the Illumina TruSeq RNA and the dUTP methods ⬇️

ARH-seq: identification of differential splicing in RNA-seq data

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

An efficient and economic enhancer mix for PCR

An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

Analysis of the DNA-binding profile and function of TALE homeoproteins reveals their specialization and specific interactions with Hox genes/proteins.

Applicability of liquid biopsies to represent the mutational profile of tumor tissue from different cancer entities

Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules

BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence

Cancer Precision Medicine: Why More Is More and DNA Is Not Enough

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

Cell type specific novel lncRNAs and circRNAs in the BLUEPRINT haematopoietic transcriptomes atlas

ChIP-Seq and RNA-Seq analyses identify components of the Wnt and Fgf signaling pathways as Prep1 target genes in mouse embryonic stem cells

Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes

Combined HAT/EZH2 modulation leads to cancer-selective cell death.

Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains

Comparative analysis of neutrophil and monocyte epigenomes

Construction and analysis of a human-chimpanzee comparative clone map.

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

Dissecting the genomic complexity underlying medulloblastoma

Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils

Endocytosis-mediated replenishment of amino acids favors cancer cell proliferation and survival in chromophobe renal cell carcinoma

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

Epigenomic and functional dynamics of human bone marrow myeloid differentiation to mature blood neutrophils

Erratum to: 'The direction of cross affects obesity after puberty in male but not female offspring'.

Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters

Gene expression variation in Down's syndrome mice allows prioritization of candidate genes

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

Human Lineage-Specific Transcriptional Regulation through GA-Binding Protein Transcription Factor Alpha (GABPa).

Hypermutation of the inactive X chromosome is a frequent event in cancer

ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing.

Impact of congenital cytomegalovirus infection on transcriptomes from archived dried blood spots in relation to long-term clinical outcome

Impaired Planar Germ Cell Division in the Testis, Caused by Dissociation of RHAMM from the Spindle, Results in Hypofertility and Seminoma

Influence of RNA extraction methods and library selection schemes on RNA-seq data

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer

Mass Cytometry-A Tool for the Curious: Networking in Berlin

Matrin 3 Binds and Stabilizes mRNA ⬇️

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia.

Network and systems biology: essential steps in virtualising drug discovery and development

Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation

Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments

Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells

Rational therapy with vigabatrin and a ketogenic diet in a patient with GAD1 deficiency

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

Regulation of the MID1 protein function is fine-tuned by a complex pattern of alternative splicing

Screening of human gene promoter activities using transfected-cell arrays

Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes

Support of a molecular tumour board by an evidence-based decision management system for precision oncology

The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle

The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability

The direction of cross affects [corrected] obesity after puberty in male but not female offspring

The hematopoietic stem cell marker VNN2 is associated with chemoresistance in pediatric B-cell precursor ALL

The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells

The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

The whole-genome landscape of medulloblastoma subtypes

Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome