List of works - Hidemasa Goto

14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage

scientific article

Aurora-B and Rho-kinase/ROCK, the two cleavage furrow kinases, independently regulate the progression of cytokinesis: possible existence of a novel cleavage furrow kinase phosphorylates ezrin/radixin/moesin (ERM)

scientific article published on 01 February 2005

Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation

scientific article (publication date: 2002)

Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process

scientific article (publication date: 7 March 2003)

Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila.

scientific article

Cdk1 coordinates timely activation of MKlp2 kinesin with relocation of the chromosome passenger complex for cytokinesis

scientific article published on 20 March 2014

Cell cycle progression by the repression of primary cilia formation in proliferating cells

scientific article

Cell cycle regulation of human CDC6 protein. Intracellular localization, interaction with the human mcm complex, and CDC2 kinase-mediated hyperphosphorylation.

scientific article

Characterization of a monoclonal antibody, HTA28, recognizing a histone H3 phosphorylation site as a useful marker of M-phase cells.

scientific article

Chk1-mediated Cdc25A degradation as a critical mechanism for normal cell cycle progression

scientific article published on 25 January 2019

Complex formation of Plk1 and INCENP required for metaphase-anaphase transition

scientific article

Current topics of functional links between primary cilia and cell cycle

scientific article

Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle.

scientific article

Cytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice

scientific article published on 6 April 2015

DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development

scientific article

Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells.

scientific article published on 18 October 2013

Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole.

scientific article

Domain- and Site-Specific Phosphorylation of Bovine NF-L by Rho-Associated Kinase ⬇️

scientific article published on April 17, 1998

Functional significance of the specific sites phosphorylated in desmin at cleavage furrow: Aurora-B may phosphorylate and regulate type III intermediate filaments during cytokinesis coordinatedly with Rho-kinase

scientific article

Inhibition of endocytic vesicle fusion by Plk1-mediated phosphorylation of vimentin during mitosis

scientific article published on 25 October 2013

Localized phosphorylation of vimentin by rho-kinase in neuroblastoma N2a cells

scientific article published on 01 October 2000

MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2.

scientific article

Mechanisms of ciliogenesis suppression in dividing cells

scientific article published on 26 September 2016

Method for the generation of antibodies specific for site and posttranslational modifications.

scientific article published in January 2014

Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1

scientific article

Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein-Aurora A pathway.

scientific article published on February 2016

New insights into roles of intermediate filament phosphorylation and progeria pathogenesis.

scientific article published on 23 March 2014

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition

scientific article

Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy?

scientific article

Nuclear Chk1 prevents premature mitotic entry.

scientific article published on 31 May 2011

PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition

scientific article

Phospho-Specific Antibody Probes of Intermediate Filament Proteins.

scientific article

Phosphorylation and reorganization of vimentin by p21-activated kinase (PAK)

scientific article (publication date: February 2002)

Phosphorylation at serine 28 and acetylation at lysine 9 of histone H3 induced by trichostatin A.

scientific article published in August 2003

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis

scientific article published on 31 October 2005

Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesis

scientific article published on 01 May 1998

Plk1 phosphorylates CLIP-170 and regulates its binding to microtubules for chromosome alignment

scientific article published on 22 January 2014

Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase.

scientific article published on 5 March 2018

Spatial Patterns of Ca2+ Signals Define Intracellular Distribution of a Signaling by Ca2+/Calmodulin-dependent Protein Kinase II ⬇️

scientific article published on October 3, 1997

Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: cleavage furrow-specific phosphorylation of intermediate filaments

scientific article published on 01 April 1999

Sphingolipids inhibit vimentin-dependent cell migration.

scientific article published on 23 April 2015

Tetraploidy in cancer and its possible link to aging

article by Kozo Tanaka et al published 1 September 2018 in Cancer Science

The p90 ribosomal S6 kinase (RSK) inhibitor BI-D1870 prevents gamma irradiation-induced apoptosis and mediates senescence via RSK- and p53-independent accumulation of p21WAF1/CIP1.

scientific article

Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells.

scientific article published on 23 April 2012

Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein

scientific journal article

p21-activated kinase PAK phosphorylates desmin at sites different from those for Rho-associated kinase

scientific article published on 01 June 2000

List of works by Hidemasa Goto

14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage

Aurora-B and Rho-kinase/ROCK, the two cleavage furrow kinases, independently regulate the progression of cytokinesis: possible existence of a novel cleavage furrow kinase phosphorylates ezrin/radixin/moesin (ERM)

Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation

Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process

Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila.

Cdk1 coordinates timely activation of MKlp2 kinesin with relocation of the chromosome passenger complex for cytokinesis

Cell cycle progression by the repression of primary cilia formation in proliferating cells

Cell cycle regulation of human CDC6 protein. Intracellular localization, interaction with the human mcm complex, and CDC2 kinase-mediated hyperphosphorylation.

Characterization of a monoclonal antibody, HTA28, recognizing a histone H3 phosphorylation site as a useful marker of M-phase cells.

Chk1-mediated Cdc25A degradation as a critical mechanism for normal cell cycle progression

Complex formation of Plk1 and INCENP required for metaphase-anaphase transition

Current topics of functional links between primary cilia and cell cycle

Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle.

Cytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice

DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development

Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells.

Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole.

Domain- and Site-Specific Phosphorylation of Bovine NF-L by Rho-Associated Kinase ⬇️

Functional significance of the specific sites phosphorylated in desmin at cleavage furrow: Aurora-B may phosphorylate and regulate type III intermediate filaments during cytokinesis coordinatedly with Rho-kinase

Inhibition of endocytic vesicle fusion by Plk1-mediated phosphorylation of vimentin during mitosis

Localized phosphorylation of vimentin by rho-kinase in neuroblastoma N2a cells

MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2.

Mechanisms of ciliogenesis suppression in dividing cells

Method for the generation of antibodies specific for site and posttranslational modifications.

Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1

Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein-Aurora A pathway.

New insights into roles of intermediate filament phosphorylation and progeria pathogenesis.

Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition

Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy?

Nuclear Chk1 prevents premature mitotic entry.

PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition

Phospho-Specific Antibody Probes of Intermediate Filament Proteins.

Phosphorylation and reorganization of vimentin by p21-activated kinase (PAK)

Phosphorylation at serine 28 and acetylation at lysine 9 of histone H3 induced by trichostatin A.

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis

Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesis

Plk1 phosphorylates CLIP-170 and regulates its binding to microtubules for chromosome alignment

Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase.

Spatial Patterns of Ca2+ Signals Define Intracellular Distribution of a Signaling by Ca2+/Calmodulin-dependent Protein Kinase II ⬇️

Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: cleavage furrow-specific phosphorylation of intermediate filaments

Sphingolipids inhibit vimentin-dependent cell migration.

Tetraploidy in cancer and its possible link to aging

The p90 ribosomal S6 kinase (RSK) inhibitor BI-D1870 prevents gamma irradiation-induced apoptosis and mediates senescence via RSK- and p53-independent accumulation of p21WAF1/CIP1.

Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells.

Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein

p21-activated kinase PAK phosphorylates desmin at sites different from those for Rho-associated kinase