Search filters

List of works by Olli-Pekka Kallioniemi

15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.

scientific article

234 Drugs with known pharmacological profiles, such as monensin, disulfiram and salinomycin, show cancer-selective inhibition of prostate cancer cell growth by increasing oxidative stress

scholarly article by Kirsi Ketola et al published June 2010 in EJC supplements

316 POSTER ErbB4 suppresses proteasomal degradation of HIF-1a and promotes survival of cancer cells in hypoxia

3Precision systems medicine in urological Tumors – Molecular profiling and functional testing

458 INVITED High-throughput RNAi screening using cell microarray technology

558 Systematic functional analysis of microRNAs by transfection of 1129 miRNAs into prostate cancer cells

A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer

scientific article published on 28 July 2002

A cell spot microarray method for production of high density siRNA transfection microarrays

scientific article

A community effort to assess and improve drug sensitivity prediction algorithms.

scientific article

A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses

scientific article

A decade of cancer gene profiling: from molecular portraits to molecular function

scientific article published on January 2010

A functional genetic screen reveals new regulators of β1-integrin activity

scientific article

A genetic epidemiological study of hereditary prostate cancer (HPC) in Finland: frequent HPCX linkage in families with late-onset disease

scientific article

A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes

scientific article

A loss-of-function genetic screening identifies novel mediators of thyroid cancer cell viability.

scientific article

A major locus for hereditary prostate cancer in Finland: localization by linkage disequilibrium of a haplotype in the HPCX region

scientific article published on 20 May 2005

A missense substitution A49T in the steroid 5-alpha-reductase gene (SRD5A2) is not associated with prostate cancer in Finland

scientific article

A new look towards BAC-based array CGH through a comprehensive comparison with oligo-based array CGH.

scientific article

A novel strategy for microarray quality control using Bayesian networks

scientific article published in November 2003

A novel transcript, VNN1-AB, as a biomarker for colorectal cancer

scientific article published on 29 March 2014

A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo

scientific article

A physical map of chromosome 20 established using fluorescence in situ hybridization and digital image analysis

scientific article published on March 1995

A strategy for identifying putative causes of gene expression variation in human cancers

article

AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

scientific article (publication date: 15 August 1997)

ANDROGEN RECEPTOR GENE AMPLIFICATION AT PRIMARY PROGRESSION PREDICTS RESPONSE TO COMBINED ANDROGEN BLOCKADE AS SECOND LINE THERAPY FOR ADVANCED PROSTATE CANCER

article

ANX7 as a Bio‐Marker in Prostate and Breast Cancer Progression

scientific article published on January 1, 2001

ANX7, a candidate tumor suppressor gene for prostate cancer

scientific article

ARLTS1 and prostate cancer risk--analysis of expression and regulation

scientific article

Abstract 5588: Functional drug sensitivity and resistance profiling of AML patient cells defines a disease-specific combination of druggable signal addictions

Abstract A62: Monensin-induced oxidative stress reduces prostate cancer cell motility and cancer stem cell markers

Aggressiveness of screen-detected breast cancers

scientific article published in January 1995

Akt inhibitor MK2206 prevents influenza pH1N1 virus infection in vitro.

scientific article

Alignment of gene expression profiles from test samples against a reference database: New method for context-specific interpretation of microarray data

scientific article

Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity

scientific article published on October 2001

An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer

scientific article

Anagrelide for Gastrointestinal Stromal Tumor

scientific article published on 07 December 2018

Analysis and Visualization of Gene Expression Microarray Data in Human Cancer Using Self-Organizing Maps

Analysis of DNA synthesis in herpes simplex virus infected cells by dual parameter flow cytometry

scientific article published in January 1989

Analysis of genetic changes underlying local recurrence of prostate carcinoma during androgen deprivation therapy.

scientific article published on December 1995

Analysis of kinase gene expression patterns across 5681 human tissue samples reveals functional genomic taxonomy of the kinome

scientific article

Androgen Receptor Gene Alterations in Finnish Male Breast Cancer

article

Androgen receptor gene alterations and chromosomal gains and losses in prostate carcinomas appearing during finasteride treatment for benign prostatic hyperplasia

scientific article published on 01 November 1999

Androgen receptor gene amplification in a recurrent prostate cancer after monotherapy with the nonsteroidal potent antiandrogen Casodex (bicalutamide) with a subsequent favorable response to maximal androgen blockade

scientific article published on 01 January 1997

Androgen receptor gene amplification: a novel molecular mechanism for endocrine therapy resistance in human prostate cancer

scientific article

Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer

scientific article published on 01 January 1997

Androgen receptor gene and hormonal therapy failure of prostate cancer

scientific article published on January 1, 1998

Androgen receptor-interacting protein HSPBAP1 facilitates growth of prostate cancer cells in androgen-deficient conditions

scientific article

Androgen regulation of micro-RNAs in prostate cancer

scientific article published on 13 October 2010

Aneuploid DNA content and high S-phase fraction of tumour cells are related to poor prognosis in patients with primary breast cancer

scientific article published on 01 March 1987

Aneuploidy facilitates oncogenic transformation via specific genetic alterations, including Twist2 upregulation

scientific article published on 20 May 2013

Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling

scientific article

Applications of fluorescence in situ hybridization in biological dosimetry and detection of disease-specific chromosome aberrations

scientific article published on January 1991

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer

scientific article

Are data from different gene expression microarray platforms comparable?

scientific article

Association of E-cadherin germ-line alterations with prostate cancer

scientific article published on 01 November 2001

Association of c-erbB-2 protein over-expression with high rate of cell proliferation, increased risk of visceral metastasis and poor long-term survival in breast cancer

scientific article published in November 1991

Association of overexpression of tumor suppressor protein p53 with rapid cell proliferation and poor prognosis in node-negative breast cancer patients

scientific article published on July 1992

Automated peak detection and cell cycle analysis of flow cytometric DNA histograms

scientific article published in July 1994

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies

scientific article

Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation

scientific article

BARD1 variants Cys557Ser and Val507Met in breast cancer predisposition

BRCA1 and BRCA2 mutations have no major role in predisposition to prostate cancer in Finland

scientific article

BRCA2 mutations in 154 finnish male breast cancer patients

scientific article

Biochip technologies in cancer research

scientific article

Break-induced replication repair of damaged forks induces genomic duplications in human cells.

scientific article

Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies

scientific article published in July 2005

Building an International Consortium for Tracking Coronavirus Health Status

scientific article published on 06 April 2020

Building an international consortium for tracking coronavirus health status

scientific article published on 02 June 2020

CGH, cDNA and tissue microarray analyses implicate FGFR2 amplification in a small subset of breast tumors.

scientific article

CHEK2 1100delC is not a risk factor for male breast cancer population

scientific article published in January 2004

CHEK2 variant I157T may be associated with increased breast cancer risk

scientific article published in September 2004

CIP2A is associated with human breast cancer aggressivity

scientific article

CIP2A signature reveals the MYC dependency of CIP2A-regulated phenotypes and its clinical association with breast cancer subtypes

scientific article

Cancer Genomes

scientific article published on 03 September 2010

Candidate genes for testicular cancer evaluated by in situ protein expression analyses on tissue microarrays

scientific article

Case studies investigating genetic heterogeneity between anatomically distinct bone marrow compartments in acute myeloid leukemia

scientific article published on 04 April 2018

Cathepsin D expression detected by immunohistochemistry has independent prognostic value in axillary node-negative breast cancer

scientific article published on January 1993

Cell of Origin Links Histotype Spectrum to Immune Microenvironment Diversity in Non-small-Cell Lung Cancer Driven by Mutant Kras and Loss of Lkb1.

scientific article published on January 2017

Chemical biology drug sensitivity screen identifies sunitinib as synergistic agent with disulfiram in prostate cancer cells

scientific article

Cigarette Smoking Alters Sympathoadrenal Regulation by Decreasing the Density of β2-Adrenoceptors. A Study of Monitored Smoking Cessation

scientific article published on 01 June 1991

Circulating tumor DNA in early-stage breast cancer: personalized biomarkers for occult metastatic disease and risk of relapse?

scientific article

Claes Lundsteen—in Memoriam

Classification of unknown primary tumors with a data-driven method based on a large microarray reference database

scientific article

Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility

scientific article published on 11 December 2006

Clinical and functional target validation using tissue and cell microarrays

scientific article

Clinical relevance of integrin alpha 4 in gastrointestinal stromal tumours.

scientific article

Clinical validation of candidate genes associated with prostate cancer progression in the CWR22 model system using tissue microarrays

article

Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies

scientific article published on 14 December 2017

Comparative genomic hybridization analysis of 38 breast cancer cell lines: a basis for interpreting complementary DNA microarray data.

scholarly article published in August 2000

Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

scientific article (publication date: 30 October 1992)

Comparative genomic hybridization gaining in popularity

article published in 1996

Comparative genomic hybridization reveals frequent gains of 20q, 8q, 11q, 12p, and 17q, and losses of 18q, 9p, and 15q in pancreatic cancer

article

Comparative genomic hybridization: a rapid new method for detecting and mapping DNA amplification in tumors

scientific article

Comparison of Affymetrix data normalization methods using 6,926 experiments across five array generations

scientific article

Comparison of CA 125 and placental alkaline phosphatase as ovarian tumor markers

scientific article published on 01 June 1987

Comparison of fresh and paraffin-embedded tissue as starting material for DNA flow cytometry and evaluation of intratumor heterogeneity

scientific article published on 01 March 1988

Comparison of structure fingerprint and molecular interaction field based methods in explaining biological similarity of small molecules in cell-based screens

scientific article

Comprehensive Drug Testing of Patient-derived Conditionally Reprogrammed Cells from Castration-resistant Prostate Cancer

scientific article

Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs

scientific article

Computer image analysis of comparative genomic hybridization.

scientific article published on January 1995

Consensus review of the clinical utility of DNA content cytometry in prostate cancer

scientific article

Consistency in drug response profiling

scientific article published in November 2016

Construction of evolutionary tree models for renal cell carcinoma from comparative genomic hybridization data.

scientific article

Contribution of ARLTS1 Cys148Arg (T442C) variant with prostate cancer risk and ARLTS1 function in prostate cancer cells

scientific article

Correction: GTI: A Novel Algorithm for Identifying Outlier Gene Expression Profiles from Integrated Microarray Datasets

scientific article published in PLoS ONE

Correction: Plasticity of Blood- and Lymphatic Endothelial Cells and Marker Identification.

scientific article published on 15 October 2013

Correction: miRNA-mRNA Integrated Analysis Reveals Roles for miRNAs in Primary Breast Tumors

scientific article published in PLoS ONE

Correlation between serum tumor marker levels and tumor proliferation in small cell lung cancer

scientific article published on 01 January 1988

Correlation of CHEK2 protein expression and c.1100delC mutation status with tumor characteristics among unselected breast cancer patients

scientific article published in February 2005

Critical comparison of virtual screening methods against the MUV data set.

scientific article

Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo

scientific article

DNA Ploidy Level and Cell Cycle Distribution in Ovarian Cancer

DNA flow cytometric analysis indicates that many breast cancers detected in the first round of mammographic screening have a low malignant potential

scientific article published in November 1988

DNA ploidy level and cell cycle distribution in ovarian cancer: relation to histopathological features of the tumor

scientific article published on 01 January 1988

Data integration from two microarray platforms identifies bi-allelic genetic inactivation of RIC8A in a breast cancer cell line

scientific article

Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer

scientific article published on December 2008

Deletion of chromosome 17p loci in breast cancer cells detected by fluorescence in situ hybridization

scientific article published in June 1992

Detecting activation of ribosomal protein S6 kinase by complementary DNA and tissue microarray analysis

scholarly article

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

scientific article

Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization

scientific article published on January 1, 1992

Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint

scientific article

Different opinions on classification of DNA histograms produced from paraffin-embedded tissue

scientific article published on 01 November 1989

Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development

scientific article

Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors

scientific article

Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling.

scientific article published on 14 August 2017

Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

scientific article published on 17 April 2013

Distance-based reconstruction of tree models for oncogenesis

scientific article published in January 2000

Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations

scientific article published on 01 April 1997

Drug response prediction by inferring pathway-response associations with kernelized Bayesian matrix factorization

scientific article published on September 2016

Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors

scientific article published on 29 May 2017

Drug-Sensitivity Screening and Genomic Characterization of 45 HPV-Negative Head and Neck Carcinoma Cell Lines for Novel Biomarkers of Drug Efficacy

scientific article published on 03 July 2018

Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response

scientific article published on 21 March 2017

Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer

scientific article

ELAC2/HPC2 involvement in hereditary and sporadic prostate cancer

scientific article (publication date: 15 August 2001)

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization

scientific article published on June 15, 1992

Elevated expression of S100A8 and S100A9 correlates with resistance to the BCL-2 inhibitor venetoclax in AML

scientific article published on 07 June 2019

Elevated expression of inhibitor of apoptosis proteins in prostate cancer

scientific article published on October 2003

ElevatederbB-2 oncoprotein levels in preoperative and follow-up serum samples define an aggressive disease course in patients with breast cancer

scientific article published on 01 February 1994

Emerging molecular biomarkers--blood-based strategies to detect and monitor cancer

scientific article published on March 2011

Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML

scientific article published on 11 November 2016

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

scientific article published on 30 March 2010

EphB2 expression across 138 human tumor types in a tissue microarray: high levels of expression in gastrointestinal cancers

scientific article published in September 2005

Epigenetics of prostate cancer and the prospect of identification of novel drug targets by RNAi screening of epigenetic enzymes

scientific article

Erratum to: Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

scholarly article published in Breast Cancer Research and Treatment

Erratum: Genome-wide scanning for linkage in Finnish breast cancer families

scholarly article published in European Journal of Human Genetics

Evaluation of camera requirements for comparative genomic hybridization

scientific article

Evaluation of cell proliferation in breast carcinoma. Comparison of Ki-67 immunohistochemical study, DNA flow cytometric analysis, and mitotic count

scientific article published on 01 March 1990

Evaluation of the role of Finnish ataxia-telangiectasia mutations in hereditary predisposition to breast cancer

scientific article published on 13 December 2006

Evaluation of the value of fluorometric serum heat stable alkaline phosphatase assay in patients operated on for ovarian tumors

Evidence for a prostate cancer susceptibility locus on the X chromosome.

article

Expression of Bcl-2 family member Bid in normal and malignant tissues

scientific article

Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome

scientific article

Expression of epidermal growth factor receptor and ERBB2 (HER-2/Neu) oncoprotein in prostatic carcinomas

scientific article published on November 1, 1992

Expression of mammary derived growth inhibitor (MDGI) results in phenotypic reversal in breast cancer

Extrachromosomal gene amplification in acute myeloid leukemia; Characterization by metaphase analysis, comparative genomic hybridization, and semi-quantitative PCR

article

FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells.

scientific article published on 16 August 2010

Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling

scientific article published in October 2001

Fiber-FISH: experiences and a refined protocol

scientific article published on 01 March 1996

Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation

scientific article

Flow Cytometric Analysis of Tumour dna Profile Related to Response to Radiotherapy and Survival in Inoperable Lung Cancer

scientific article published on 01 January 1990

Flow cytometric DNA analysis of 199 histologically favourable or unfavourable non-Hodgkin lymphomas

scientific article published on January 1989

Flow cytometric analysis of DNA ploidy and S-phase fraction from prostatic carcinomas: implications for prognosis and response to endocrine therapy

scientific article published on September 1991

Frequent loss of the 11q14-24 region in chronic lymphocytic leukemia: A study by comparative genomic hybridization

article

Frequent loss of the 11q14-24 region in chronic lymphocytic leukemia: a study by comparative genomic hybridization. Tampere CLL Group

scientific article published on 01 August 1997

From chromosomal alterations to target genes for therapy: integrating cytogenetic and functional genomic views of the breast cancer genome

scientific article

Functional evidence implicating S100P in prostate cancer progression

scientific article

Functional genomics and transcriptomics of prostate cancer: promises and limitations

scientific article

Functional profiling of precursor MicroRNAs identifies MicroRNAs essential for glioma proliferation

scientific article

Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer

scientific article

GTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets

scientific article

Gain of 17q24-qter detected by comparative genomic hybridization in malignant tumors from patients with von Recklinghausen's neurofibromatosis

scientific article published on 01 October 1996

Gains and losses of DNA sequences in malignant mesothelioma by comparative genomic hybridization

scientific article published on 01 July 1996

Gene Copy Number Analysis by Fluorescencein SituHybridization and Comparative Genomic Hybridization

scientific article published on February 1, 1996

Gene chip technique and associated bioinformatics

scientific article published in January 2002

Gene-Expression Profiles in Hereditary Breast Cancer

article

Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome

scientific article

Genetic Instability of Influenza pH1N1 Viruses

scientific article published on 2 October 2014

Genetic aberrations detected by comparative genomic hybridization predict outcome in node-negative breast cancer

scientific article published on October 1995

Genetic aberrations in adrenocortical tumors detected using comparative genomic hybridization correlate with tumor size and malignancy

scientific article published in September 1996

Genetic basis and clonal evolution of human prostate cancer

scientific article published on January 1996

Genetic changes associated with the acquisition of androgen-independent growth, tumorigenicity and metastatic potential in a prostate cancer model

scientific article

Genetic changes in familial prostate cancer by comparative genomic hybridization

scientific article published on 01 February 2001

Genetic changes in intraductal breast cancer detected by comparative genomic hybridization.

scientific article published on April 1997

Genetic changes in primary and recurrent prostate cancer by comparative genomic hybridization

scientific article published on 01 January 1995

Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer.

scientific article

Genome screening by comparative genomic hybridization

scientific article published on October 1, 1997

Genome-wide scan for linkage in finnish hereditary prostate cancer (HPC) families identifies novel susceptibility loci at 11q14 and 3p25-26.

scientific article

Genome-wide scanning for linkage in Finnish breast cancer families

article

Genotyping of adrenocortical tumors: very frequent deletions of the MEN1 locus in 11q13 and of a 1-centimorgan region in 2p16

scientific article published on 01 February 1999

Germline TP53 alterations in Finnish breast cancer families are rare and occur at conserved mutation-prone sites

scientific article published on January 2001

Germline TP53 mutations in Finnish breast cancer patients

scientific article published on 12 March 2000

Germline alterations of the RNASEL gene, a candidate HPC1 gene at 1q25, in patients and families with prostate cancer

scientific article published on 8 April 2002

Germline mutations in the ribonuclease L gene in families showing linkage with HPC1

scientific article (publication date: February 2002)

Growth properties and composition of cytoskeletal and cytocontractile proteins in aortic cells isolated and cultured from normal and atherosclerotic rabbits

article

HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation

scientific article

HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia.

scientific article published on 8 August 2016

Haplotype analysis in Icelandic and Finnish BRCA2 999del5 breast cancer families

scientific article published in October 2001

Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis

scientific article

Hereditary prostate cancer in Finland: fine-mapping validates 3p26 as a major predisposition locus

scholarly article by Annika R�kman et al published 11 November 2004 in Human Genetics

Herpes virus specified early proteins induce cellular DNA synthesis in virus infected cervical cancer cells

High frequency of BRAF mutations in nevi

scientific article

High resolution mapping using fluorescence in situ hybridization to extended DNA fibers prepared from agarose-embedded cells

scientific article published on November 1994

High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells

scientific article (publication date: 2013)

High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion

scientific article

High-throughput cell-based compound screen identifies pinosylvin methyl ether and tanshinone IIA as inhibitors of castration-resistant prostate cancer

scientific article published on March 2016

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth

scientific article

High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth

scientific article

High-throughput tissue microarray analysis of cyclin E gene amplification and overexpression in urinary bladder cancer

scientific article published in September 2000

High-throughput tissue microarray analysis to evaluate genes uncovered by cDNA microarray screening in renal cell carcinoma

scientific article published on April 1999

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer

scientific article

Hormone therapy failure in human prostate cancer: analysis by complementary DNA and tissue microarrays.

scholarly article

Human Protein Atlas charts a diverse terrain

ITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer

scientific article

Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia

scientific article

Identification of differentially expressed genes in human gliomas by DNA microarray and tissue chip techniques.

scientific article published on December 2000

Identification of fusion genes in breast cancer by paired-end RNA-sequencing

scientific article

Identification of gains and losses of DNA sequences in primary bladder cancer by comparative genomic hybridization

scientific article published on 01 March 1995

Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact

scientific article

Identification of microRNAs inhibiting TGF-β-induced IL-11 production in bone metastatic breast cancer cells

scientific article

Identification of structural features in chemicals associated with cancer drug response: a systematic data-driven analysis.

scientific article

Identification of target genes in laryngeal squamous cell carcinoma by high-resolution copy number and gene expression microarray analyses

scientific article published on 22 May 2006

Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML

scholarly article by Oscar Brück et al published 20 June 2018 in Leukemia

Immunoelectron-microscopic localization of a proliferation-associated antigen Ki-67 in MCF-7 cells

scientific article published in September 1990

Immunohistochemical determination of estrogen and progesterone receptors in human breast carcinoma. Correlation with histopathology and DNA flow cytometry

scientific article published on 01 May 1989

Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose-response data

scientific article

Improved prognostic impact of S-phase values from paraffin-embedded breast and prostate carcinomas after correcting for nuclear slicing.

scientific article published on January 1991

Improved technique for analysis of formalin-fixed, paraffin-embedded tumors by fluorescence in situ hybridization

scientific article published on June 1994

Improving the prognostic value of DNA flow cytometry in breast cancer by combining DNA index and S-phase fraction: A proposed classification of DNA histograms in breast cancer

scientific article published on 01 November 1988

In vivo amplification of the androgen receptor gene and progression of human prostate cancer

scientific article

Increased copy number at 17q22-q24 by CGH in breast cancer is due to high-level amplification of two separate regions

scientific article published on 01 December 1997

Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer

scientific article

Individual and stable autoantibody repertoires in healthy individuals

scientific article published on 01 February 2019

Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.

scientific article published on 20 September 2013

Inferring tree models for oncogenesis from comparative genome hybridization data

scientific article

Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis

scientific article published on 9 September 2013

Integrated breast cancer genomics

scientific article published on December 2006

Integration of metabolomics and expression of glycerol-3-phosphate acyltransferase (GPAM) in breast cancer-link to patient survival, hormone receptor status, and metabolic profiling

scientific article published on 15 December 2011

Integrative and personalized QSAR analysis in cancer by kernelized Bayesian matrix factorization

scientific article

Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2

scientific article

Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer

scientific article published on 14 September 2011

Integrin trafficking regulated by Rab21 is necessary for cytokinesis

scientific article published on September 2008

Inter-laboratory comparison of DNA flow cytometric results from paraffin-embedded breast carcinomas

scientific article published on 01 November 1990

Interaction with ErbB4 promotes hypoxia-inducible factor-1α signaling.

scientific article published on 3 February 2012

Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells

article published in 2010

International network of cancer genome projects

scientific article

Intrinsic resistance to PIM kinase inhibition in AML through p38α-mediated feedback activation of mTOR signaling

scientific article published on 05 June 2016

Introducing Tissue Microarrays to Molecular Pathology

scientific article published on 11 October 2012

JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell-induced protection of AML.

scientific article

KIT pathway upregulation predicts dasatinib efficacy in acute myeloid leukemia

scientific article published on 17 July 2020

KRAS Oncogene Rearrangements and Gene Fusions: Unexpected Rare Encounters in Late-Stage Prostate Cancers: Table 1.

article

Linking chromosomal clues

scientific article published on 01 January 1997

Lipoprotein uptake in primary cell cultures of rabbit atherosclerotic lesions

article

Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression

scientific article

Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast

scientific article (publication date: 3 April 2003)

Low biological aggressiveness of screen-detected lung cancers may indicate over-diagnosis

scientific article published on 01 March 1996

Low proportion of BRCA1 and BRCA2 mutations in Finnish breast cancer families: evidence for additional susceptibility genes

article

Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models

scientific article published on 26 September 2011

Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search

scientific article

Mammary-derived growth inhibitor alters traffic of EGFR and induces a novel form of cetuximab resistance

scientific article published on 13 October 2009

Mechanically stretched chromosomes as targets for high-resolution FISH mapping

scientific article published on 01 August 1995

Medicine: Profile of a tumour

Metabolomic Profiling of Extracellular Vesicles and Alternative Normalization Methods Reveal Enriched Metabolites and Strategies to Study Prostate Cancer-Related Changes

scientific article published on 23 August 2017

MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer

scientific article

MicroRNA in prostate, bladder, and kidney cancer: a systematic review.

scientific article published on February 2011

MicroRNA-135b regulates ERα, AR and HIF1AN and affects breast and prostate cancer cell growth

scientific article published on 21 March 2015

Molecular Cytogenetics of Human Breast Cancer

scientific article published on January 1, 1994

Molecular characteristics of inherited breast tumors.

scientific article published on 12 March 2000

Molecular cytogenetic analysis of 11 new breast cancer cell lines

scientific article published on December 1999

Molecular cytogenetic mapping of 24 CEPH YACs and 24 gene-specific large insert probes to chromosome 17

article

Molecular cytogenetics of primary breast cancer by CGH

article by Mika Tirkkonen et al published March 1998 in Genes, Chromosomes and Cancer

Molecular cytogenetics: diagnosis and prognostic assessment

scientific article published on December 1, 1992

Monensin Induced Oxidative Stress Reduces Prostate Cancer Cell Migration and Cancer Stem Cell Population

Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells

scientific article published on December 2010

Monitoring therapy responses at the leukemic subclone level by ultra-deep amplicon resequencing in acute myeloid leukemia

scientific article published on 31 October 2016

Morphological spot counting from stacked images for automated analysis of gene copy numbers by fluorescence in situ hybridization

scientific article published on January 2002

Multiple founder effects and geographical clustering of BRCA1 and BRCA2 families in Finland

article

NMD microarray analysis for rapid genome-wide screen of mutated genes in cancer.

scientific article

Nationwide cancer family ascertainment using Finnish Cancer Registry data on family names and places of birth for 35,761 prostate cancer patients

scientific article

New paraoxonase 1 polymorphism I102V and the risk of prostate cancer in Finnish men.

scientific article

New prognostic factors in prostatic carcinoma

scientific article published on January 1993

New studies on breast cancer to predict disease outcome and clinical use of these new tests

scientific article published on 01 January 1991

No fumarate hydratase (FH) mutations in hereditary prostate cancer

scientific article published in March 2003

Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ.

scientific article published on 26 November 2012

Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer

scientific article published on 8 August 2004

Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia

scientific article published on 27 February 2014

Novel drug candidates for blast phase chronic myeloid leukemia from high-throughput drug sensitivity and resistance testing

scientific article published on May 2015

Novel findings in gene expression detected in human osteosarcoma by cDNA microarray

scientific article published on December 2000

Novel genomic aberrations in testicular germ cell tumors by array-CGH, and associated gene expression changes

scientific article

Novel human vascular endothelial growth factor genes VEGF-B and VEGF-C localize to chromosomes 11q13 and 4q34, respectively

scientific article

Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation

scientific article published on 06 December 2013

Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression

scientific article published on 17 March 2011

Nuclear DNA content characteristics of 129 high grade malignancy non-Hodgkin lymphomas

Nuclear DNA content of non-endemic Burkitt's lymphoma

scientific article

On the organization of bioinformatics core services in biology-based research institutes

scientific article published in 2011

Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication

scientific article published on 18 February 2016

Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors

scientific article published on August 1, 1994

P26. MicroRNA expression profiling and functional screening in bone metastatic breast cancer cells

PD-L1 tumor-associated macrophages and PD-1 tumor-infiltrating lymphocytes predict survival in primary testicular lymphoma

scholarly article by Marjukka Pollari et al published November 2018 in Haematologica

PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cells

scientific article

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.

scientific article

Physical mapping of chromosome 17 cosmids by fluorescence in situ hybridization and digital image analysis

scientific article published on March 1994

Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells

scientific article

Plasticity of blood- and lymphatic endothelial cells and marker identification

scientific article (publication date: 2013)

Population-Based Study of BRCA1 and BRCA2 Mutations in 1035 Unselected Finnish Breast Cancer Patients

scientific article published on 01 September 2000

Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma

scientific article

Primary invasive and in situ vaginal carcinoma. Flow cytometric analysis of DNA aneuploidy and cell proliferation from archival paraffin-embedded tissue

scientific article published on September 1989

Primary undifferentiated small cell carcinoma of the esophagus: clinicopathological and flow cytometric evaluation of eight cases

scientific article

Profiling Genetic Variation along the Androgen Biosynthesis and Metabolism Pathways Implicates Several Single Nucleotide Polymorphisms and Their Combinations as Prostate Cancer Risk Factors

scholarly article by Nina Mononen et al published 15 January 2006 in Cancer Research

Prognosis of breast tumors by DNA flow cytometric analysis

scientific article published on 01 January 1989

Prognostic assessment in stage I ovarian cancer using a discriminant analysis with clinicopathological and DNA flow cytometric data

scientific article

Prognostic factors in recurrent breast cancer: relationships to site of recurrence, disease-free interval, female sex steroid receptors, ploidy and histological malignancy grading

scientific article

Prognostic impact of ANX7-GTPase in metastatic and HER2-negative breast cancer patients

scientific article published in April 2004

Prognostic impact of DNA-ploidy and S-phase fraction

Prognostic significance of dna index, multiploidy, and S-phase fraction in ovarian cancer

scientific article published on 01 January 1988

Prognostic value of analysis of DNA in pancreatic adenocarcinoma by flow cytometry

scientific article published on 01 October 1991

Prognostic value of cells with more than 5c DNA content in node-negative breast cancer as determined by image cytometry from tissue sections

article

Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer

scholarly article by Jarle Bruun et al published September 2018 in Molecular Oncology

Proliferating cell nuclear antigen immunohistochemistry using monoclonal antibody 19A2 and a new antigen retrieval technique has prognostic impact in archival paraffin-embedded node-negative breast cancer.

scientific article published in April 1993

Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines

scientific article

ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

article

Publisher Correction: Building an international consortium for tracking coronavirus health status

scientific article published on 26 June 2020

Quality control of CGH: Impact of metaphase chromosomes and the dynamic range of hybridization

scientific article published on 01 July 1997

Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies

scientific article

RESPONSE: Re: Population-Based Study of BRCA1 and BRCA2 Mutations in 1035 Unselected Finnish Breast Cancer Patients

article

RNAi microarray analysis in cultured mammalian cells

scientific article

Reanalysis of RNA-sequencing data reveals several additional fusion genes with multiple isoforms

scientific article

Relatives of prostate cancer patients have an increased risk of prostate and stomach cancers: a population-based, cancer registry study in Finland

scientific article published on 01 April 2001

Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.

scientific article

Role of ErbB4 in breast cancer

scientific article published on 03 May 2008

SATB2 in Combination With Cytokeratin 20 Identifies Over 95% of all Colorectal Carcinomas

article

SHARPIN is an endogenous inhibitor of β1-integrin activation

scientific article

STRN-ALK rearranged pediatric malignant peritoneal mesothelioma - Functional testing of 527 cancer drugs in patient-derived cancer cells

scientific article published on 30 January 2021

Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress

scientific article published on January 2012

Sensitive detection of chromosome copy number aberrations in prostate cancer by fluorescence in situ hybridization

scientific article published on September 1994

Serum CA 125 in acute pelvic inflammatory disease

scientific article published on 01 May 1989

Serum CA 15-3 assay in the diagnosis and follow-up of breast cancer

scientific article

Simulation Toolbox for 3D-FISH Spot-Counting Algorithms

scholarly article by A.M. Grigoryan et al published June 2002 in Real Time Imaging

Small Subgroup of Aggressive, Highly Proliferative Prostatic Carcinomas Defined by p53 Accumulation

scientific article published on 01 June 1992

Somatic STAT3 mutations in large granular lymphocytic leukemia

scientific article

Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus

scientific article

Somatic genetic alterations inBRCA2-associated and sporadic male breast cancer

scientific article published on 01 January 1999

Spatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras-driven lung tumours

scientific article published on 14 February 2018

Steroid receptors and Ki-67 reactivity in ovarian cancer and in normal ovary: Correlation with dna flow cytometry, biochemical receptor assay, and patient survival

scientific article published on 01 December 1990

Suppression of autologous mixed leukocyte reaction in type 1 diabetes mellitus by in vivo-activated T lymphocytes

Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays.

scientific article published in February 1999

Susceptibility genes of familial breast cancer in Finland

scientific paper

Systematic Identification of MicroRNAs That Impact on Proliferation of Prostate Cancer Cells and Display Changed Expression in Tumor Tissue

scientific article published on 19 October 2015

Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells

scientific article

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

scientific article published on 19 September 2008

Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer

scientific article

Systematic drug sensitivity testing reveals synergistic growth inhibition by dasatinib or mTOR inhibitors with paclitaxel in ovarian granulosa cell tumor cells

scientific article published on 16 January 2017

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion

scientific article published on 28 November 2011

Systemic analysis of gene expression profiles identifies ErbB3 as a potential drug target in pediatric alveolar rhabdomyosarcoma

scientific article

Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis.

scientific article published on 14 November 2017

T-cell inflamed tumor microenvironment predicts favorable prognosis in primary testicular lymphoma

scholarly article by Suvi-Katri Leivonen et al published February 2019 in Haematologica

TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming

scientific article published on November 2006

The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions

scientific article published on 18 March 2008

The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions.

scientific article

The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells

scientific article published on 24 November 2012

The gene expression landscape of breast cancer is shaped by tumor protein p53 status and epithelial-mesenchymal transition

scientific article published on 27 July 2012

The human gene for xanthine dehydrogenase (XDH) is localized on chromosome band 2q22.

scientific article

The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia

scientific article published on 17 August 2017

The impact of low-frequency and rare variants on lipid levels

scientific article published on 11 May 2015

The miR-15a-miR-16-1 locus is homozygously deleted in a subset of prostate cancers

scientific article published on 31 March 2011

The transcription factor Sox11 is a prognostic factor for improved recurrence-free survival in epithelial ovarian cancer

scientific article published on 9 March 2009

The weibull distribution based normalization method for affymetrix gene expression microarray data

article

Thymidylate synthase expression predicts the response to 5-fluorouracil-based adjuvant therapy in pancreatic cancer

scientific article published in September 2003

Tissue microarray technology for high-throughput molecular profiling of cancer

scientific article

Tissue microarrays (TMAs) for high-throughput molecular pathology research

scientific article published in October 2001

Tissue microarrays for gene amplification surveys in many different tumor types.

scientific article published in August 1999

Tissue microarrays for high-throughput molecular profiling of tumor specimens

scientific article (publication date: July 1998)

Tissue microarrays for high-throughput profiling in molecular oncology.

scientific article published on 12 March 2000

Tissue microarrays for rapid linking of molecular changes to clinical endpoints

scientific article

Tissue microarrays: what will they bring to molecular and anatomic pathology?

scientific article

Topoisomerase-II alpha is upregulated in malignant peripheral nerve sheath tumors and associated with clinical outcome

scientific article published in December 2003

Transcriptome teleonomy and scavenger lipidomics of albumin and alpha 1-acid glycoproteins: contextual genome-wide ontology enrichment as evidence for the epigenetic code?

Tumour DNA ploidy as an independent prognostic factor in breast cancer

scientific article

Two percent of Finnish prostate cancer patients have a germ-line mutation in the hormone-binding domain of the androgen receptor gene

scientific article published on 01 November 2000

Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors

scientific article

Visual mapping by fiber-FISH.

scientific article published on November 1995

[Flow cytometry of cervical cell changes]

scientific article published on 01 January 1988

[From gene chips to biochips: challenges and possibilities of the new biotechnology]

scientific article published on 01 January 2002

[Identification of prognostic parameters for renal cell carcinoma by cDNA arrays and cell chips]

scientific article published on 01 January 1999

[Mammographic screening confirmation of breast cancer biological characteristics--a flow cytometric study]

scientific article published on 01 January 1989

c-Jun N-terminal kinase phosphorylation of MARCKSL1 determines actin stability and migration in neurons and in cancer cells

scientific article

c-erbB-2 in astrocytomas: infrequent overexpression by immunohistochemistry and absence of gene amplification by fluorescence in situ hybridization

scientific article

miR-183 in prostate cancer cells positively regulates synthesis and serum levels of prostate-specific antigen

scientific article

miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors

scientific article (publication date: 22 February 2011)