List of works - Karl Werdan

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data

scientific article

Mechanical circulatory support in cardiogenic shock

scientific article

Cardiovascular disease, risk factors and heart rate variability in the elderly general population: design and objectives of the CARdiovascular disease, Living and Ageing in Halle (CARLA) Study

scientific article

Cardiovascular diseases, risk factors and short-term heart rate variability in an elderly general population: the CARLA study 2002-2006.

scientific article

Further evaluation of plasma sphingomyelin levels as a risk factor for coronary artery disease

scientific article

Mechanisms of infective endocarditis: pathogen-host interaction and risk states

scientific article published on 19 November 2013

Impaired regulation of cardiac function in sepsis, SIRS, and MODS.

scientific article

Association of statin therapy and increased survival in patients with multiple organ dysfunction syndrome

scientific article

Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanisms

scientific article

Ivabradine in combination with beta-blocker improves symptoms and quality of life in patients with stable angina pectoris: results from the ADDITIONS study

scientific article

Cardiogenic shock due to myocardial infarction: diagnosis, monitoring and treatment: a German-Austrian S3 Guideline

scientific article

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

scientific article (publication date: 27 March 2015)

Septic cardiomyopathy - A not yet discovered cardiomyopathy?

scientific article

Prevalence of symptomatic heart failure with reduced and with normal ejection fraction in an elderly general population-the CARLA study

scientific article

Interaction of vascular smooth muscle cells and monocytes by soluble factors synergistically enhances IL-6 and MCP-1 production

scientific article

Heart rate as an independent risk factor in patients with multiple organ dysfunction: a prospective, observational study

scientific article published on November 3, 2011

Septic cardiomyopathy: hemodynamic quantification, occurrence, and prognostic implications

scientific article

Apoptosis contributes to septic cardiomyopathy and is improved by simvastatin therapy

scientific article

Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome

scientific article

Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures

scientific article

The ICM research agenda on extracorporeal life support

scientific article

Reducing elevated heart rate in patients with multiple organ dysfunction syndrome by the I f (funny channel current) inhibitor ivabradine

scientific article published on June 3, 2011

Mitochondrial dysfunction in sepsis: evidence from bacteraemic baboons and endotoxaemic rabbits

scientific article

Concept for a study design in patients with severe community-acquired pneumonia: A randomised controlled trial with a novel IGM-enriched immunoglobulin preparation - The CIGMA study

scientific article

In vitro comparison of dabigatran, unfractionated heparin, and low-molecular-weight heparin in preventing thrombus formation on mechanical heart valves

scientific article

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

scientific article (published 2011-07-06)

Chemo- and ergoreflexes in health, disease and ageing

scientific article

Association of childhood and adult socioeconomic indicators with cardiovascular risk factors and its modification by age: the CARLA Study 2002-2006

scientific article published on May 10, 2011

Impedance cardiography: a useful and reliable tool in optimization of cardiac resynchronization devices

scientific article

Is external defibrillation an electric threat for bystanders?

scientific article

Contribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis

scientific article

Severity of cardiac impairment in the early stage of community-acquired sepsis determines worse prognosis

scientific article

Endotoxin-activated cultured neonatal rat cardiomyocytes express functional surface-associated interleukin-1alpha

scientific journal article

Effectiveness of Ivabradine Treatment in Different Subpopulations with Stable Angina in Clinical Practice: A Pooled Analysis of Observational Studies

scientific article

The alteration of autonomic function in multiple organ dysfunction syndrome

scientific article

Staphylococcus aureus α-Toxin Triggers the Synthesis of B-Cell Lymphoma 3 by Human Platelets

scientific article published on January 28, 2011

Effects of aprotinin on gene expression and protein synthesis after ischemia and reperfusion in rats

scientific article

Regional differences in body fat distributions among people with comparable body mass index: a comparison across six German population-based surveys

scientific article

Inhibition of cardiac pacemaker channel hHCN2 depends on intercalation of lipopolysaccharide into channel-containing membrane microdomains

scientific article

Rehabilitation in Patients With Coronary Heart Disease: Participation and Its Effect on Prognosis

scientific article

Different treatment options in chronic coronary artery disease: when is it the time for medical treatment, percutaneous coronary intervention or aortocoronary bypass surgery?

scientific article

Association of Serum Thyrotropin with Anthropometric Markers of Obesity in the General Population

scientific article

Ivabradine in Combination with Metoprolol Improves Symptoms and Quality of Life in Patients with Stable Angina Pectoris: A post hoc Analysis from the ADDITIONS Trial

scientific article published on October 27, 2015

C-reactive protein levels and genetic variants of CRP as prognostic markers for combined cardiovascular endpoint (cardiovascular death, death from stroke, myocardial infarction, and stroke/TIA).

scientific article

Association of health behaviour with heart rate variability: a population-based study

scientific article

Altered interleukin-1 receptor antagonist and interleukin-18 mRNA expression in myocardial tissues of patients with dilatated cardiomyopathy

scientific article

Effect of inflammatory mediators on cardiovascular function

scientific article

Impaired chemoreflex sensitivity in adult patients with multiple organ dysfunction syndrome--the potential role of disease severity

scientific article

Advances in the management of heart failure: the role of ivabradine

scientific article

List of works by Karl Werdan

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data

Mechanical circulatory support in cardiogenic shock

Cardiovascular disease, risk factors and heart rate variability in the elderly general population: design and objectives of the CARdiovascular disease, Living and Ageing in Halle (CARLA) Study

Cardiovascular diseases, risk factors and short-term heart rate variability in an elderly general population: the CARLA study 2002-2006.

Further evaluation of plasma sphingomyelin levels as a risk factor for coronary artery disease

Mechanisms of infective endocarditis: pathogen-host interaction and risk states

Impaired regulation of cardiac function in sepsis, SIRS, and MODS.

Association of statin therapy and increased survival in patients with multiple organ dysfunction syndrome

Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanisms

Ivabradine in combination with beta-blocker improves symptoms and quality of life in patients with stable angina pectoris: results from the ADDITIONS study

Cardiogenic shock due to myocardial infarction: diagnosis, monitoring and treatment: a German-Austrian S3 Guideline

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

Septic cardiomyopathy - A not yet discovered cardiomyopathy?

Prevalence of symptomatic heart failure with reduced and with normal ejection fraction in an elderly general population-the CARLA study

Interaction of vascular smooth muscle cells and monocytes by soluble factors synergistically enhances IL-6 and MCP-1 production

Heart rate as an independent risk factor in patients with multiple organ dysfunction: a prospective, observational study

Septic cardiomyopathy: hemodynamic quantification, occurrence, and prognostic implications

Apoptosis contributes to septic cardiomyopathy and is improved by simvastatin therapy

Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome

Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures

The ICM research agenda on extracorporeal life support

Reducing elevated heart rate in patients with multiple organ dysfunction syndrome by the I f (funny channel current) inhibitor ivabradine

Mitochondrial dysfunction in sepsis: evidence from bacteraemic baboons and endotoxaemic rabbits

Concept for a study design in patients with severe community-acquired pneumonia: A randomised controlled trial with a novel IGM-enriched immunoglobulin preparation - The CIGMA study

In vitro comparison of dabigatran, unfractionated heparin, and low-molecular-weight heparin in preventing thrombus formation on mechanical heart valves

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

Chemo- and ergoreflexes in health, disease and ageing

Association of childhood and adult socioeconomic indicators with cardiovascular risk factors and its modification by age: the CARLA Study 2002-2006

Impedance cardiography: a useful and reliable tool in optimization of cardiac resynchronization devices

Is external defibrillation an electric threat for bystanders?

Contribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis

Severity of cardiac impairment in the early stage of community-acquired sepsis determines worse prognosis

Endotoxin-activated cultured neonatal rat cardiomyocytes express functional surface-associated interleukin-1alpha

Effectiveness of Ivabradine Treatment in Different Subpopulations with Stable Angina in Clinical Practice: A Pooled Analysis of Observational Studies

The alteration of autonomic function in multiple organ dysfunction syndrome

Staphylococcus aureus α-Toxin Triggers the Synthesis of B-Cell Lymphoma 3 by Human Platelets

Effects of aprotinin on gene expression and protein synthesis after ischemia and reperfusion in rats

Regional differences in body fat distributions among people with comparable body mass index: a comparison across six German population-based surveys

Inhibition of cardiac pacemaker channel hHCN2 depends on intercalation of lipopolysaccharide into channel-containing membrane microdomains

Rehabilitation in Patients With Coronary Heart Disease: Participation and Its Effect on Prognosis

Different treatment options in chronic coronary artery disease: when is it the time for medical treatment, percutaneous coronary intervention or aortocoronary bypass surgery?

Association of Serum Thyrotropin with Anthropometric Markers of Obesity in the General Population

Ivabradine in Combination with Metoprolol Improves Symptoms and Quality of Life in Patients with Stable Angina Pectoris: A post hoc Analysis from the ADDITIONS Trial

C-reactive protein levels and genetic variants of CRP as prognostic markers for combined cardiovascular endpoint (cardiovascular death, death from stroke, myocardial infarction, and stroke/TIA).

Association of health behaviour with heart rate variability: a population-based study

Altered interleukin-1 receptor antagonist and interleukin-18 mRNA expression in myocardial tissues of patients with dilatated cardiomyopathy

Effect of inflammatory mediators on cardiovascular function

Impaired chemoreflex sensitivity in adult patients with multiple organ dysfunction syndrome--the potential role of disease severity

Advances in the management of heart failure: the role of ivabradine