List of works - Karl Werdan

Advances in the management of heart failure: the role of ivabradine

scientific article

Altered interleukin-1 receptor antagonist and interleukin-18 mRNA expression in myocardial tissues of patients with dilatated cardiomyopathy

scientific article

Anticoagulation in atrial fibrillation: NOAC's the word

scientific article

Apoptosis contributes to septic cardiomyopathy and is improved by simvastatin therapy

scientific article

Association between autonomic nervous dysfunction and cellular inflammation in end-stage renal disease

scientific article

Association of Serum Thyrotropin with Anthropometric Markers of Obesity in the General Population

scientific article

Association of childhood and adult socioeconomic indicators with cardiovascular risk factors and its modification by age: the CARLA Study 2002-2006 ⬇️

scientific article published on May 10, 2011

Association of health behaviour with heart rate variability: a population-based study

scientific article

Association of statin therapy and increased survival in patients with multiple organ dysfunction syndrome

scientific article

Atypical course of a persistent left superior vena cava through the left atrium ⬇️

scientific article published on June 17, 2011

C-reactive protein levels and genetic variants of CRP as prognostic markers for combined cardiovascular endpoint (cardiovascular death, death from stroke, myocardial infarction, and stroke/TIA).

scientific article

Cardiogenic shock due to myocardial infarction: diagnosis, monitoring and treatment: a German-Austrian S3 Guideline

scientific article

Cardiovascular disease, risk factors and heart rate variability in the elderly general population: design and objectives of the CARdiovascular disease, Living and Ageing in Halle (CARLA) Study

scientific article

Cardiovascular diseases, risk factors and short-term heart rate variability in an elderly general population: the CARLA study 2002-2006.

scientific article

Changes of individual perception in psychosocial stressors related to German reunification in 1989/1990 and cardiovascular risk factors and cardiovascular diseases in a population-based study in East Germany

scientific article

Chemo- and ergoreflexes in health, disease and ageing

scientific article

Concept for a study design in patients with severe community-acquired pneumonia: A randomised controlled trial with a novel IGM-enriched immunoglobulin preparation - The CIGMA study

scientific article

Contribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis

scientific article

Different treatment options in chronic coronary artery disease: when is it the time for medical treatment, percutaneous coronary intervention or aortocoronary bypass surgery?

scientific article

Direct inhibition, but indirect sensitization of pacemaker activity to sympathetic tone by the interaction of endotoxin with HCN-channels

scientific article

Directed expression of dominant-negative p73 enables proliferation of cardiomyocytes in mice

scientific article

Drug-eluting stents versus bare-metal stents in acute myocardial infarction with cardiogenic shock

scientific article

Effect of inflammatory mediators on cardiovascular function

scientific article

Effectiveness of Ivabradine Treatment in Different Subpopulations with Stable Angina in Clinical Practice: A Pooled Analysis of Observational Studies

scientific article

Effects of aprotinin on gene expression and protein synthesis after ischemia and reperfusion in rats

scientific article

Efficacy of enoxaparin, certoparin and dalteparin in preventing cardiac catheter thrombosis: an in vitro approach

scientific article

Embolic events caused by aortic thrombi: An underestimated entity? ⬇️

scientific article published on February 1, 2013

Endotoxin-activated cultured neonatal rat cardiomyocytes express functional surface-associated interleukin-1alpha

scientific journal article

Extracorporeal life support during cardiac arrest and cardiogenic shock-how good is the evidence really?

scientific article

Further evaluation of plasma sphingomyelin levels as a risk factor for coronary artery disease

scientific article

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data

scientific article

Heart rate as an independent risk factor in patients with multiple organ dysfunction: a prospective, observational study ⬇️

scientific article published on November 3, 2011

Impaired chemoreflex sensitivity in adult patients with multiple organ dysfunction syndrome--the potential role of disease severity

scientific article

Impaired regulation of cardiac function in sepsis, SIRS, and MODS.

scientific article

Impedance cardiography: a useful and reliable tool in optimization of cardiac resynchronization devices

scientific article

In vitro comparison of dabigatran, unfractionated heparin, and low-molecular-weight heparin in preventing thrombus formation on mechanical heart valves

scientific article

Inhibition of cardiac pacemaker channel hHCN2 depends on intercalation of lipopolysaccharide into channel-containing membrane microdomains

scientific article

Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome

scientific article

Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome

scientific article (published 2012-02-15)

Interaction of vascular smooth muscle cells and monocytes by soluble factors synergistically enhances IL-6 and MCP-1 production

scientific article

Interleukin-1 potently contributes to 25-hydroxycholesterol-induced synergistic cytokine production in smooth muscle cell-monocyte interactions

scientific article

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

scientific article (publication date: 27 March 2015)

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

scientific article (published 2011-07-06)

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

scientific article

Is external defibrillation an electric threat for bystanders?

scientific article

Ivabradine in Combination with Metoprolol Improves Symptoms and Quality of Life in Patients with Stable Angina Pectoris: A post hoc Analysis from the ADDITIONS Trial

scientific article

Ivabradine in combination with Beta-blockers in patients with chronic stable angina after percutaneous coronary intervention

scientific article

Ivabradine in combination with beta-blocker improves symptoms and quality of life in patients with stable angina pectoris: results from the ADDITIONS study

scientific article

Mechanical circulatory support in cardiogenic shock

scientific article

Mechanisms of infective endocarditis: pathogen-host interaction and risk states

scientific article published on 19 November 2013

Mitochondrial dysfunction in sepsis: evidence from bacteraemic baboons and endotoxaemic rabbits

scientific article

Neutrophils process interleukin-1beta and interleukin-18 precursors in a caspase-1-like fashion--processing is inhibited by human vascular smooth muscle cells.

scientific article

Non-compaction cardiomyopathy with diffuse left coronary artery fistulae as a rare cause of congestive heart failure ⬇️

scientific article published on June 19, 2012

Performance of Sokolow-Lyon index in detection of echocardiographically diagnosed left ventricular hypertrophy in a normal Eastern German population - results of the CARLA study

scientific article

Periodontal conditions and incidence of new cardiovascular events among patients with coronary vascular disease

scientific article

Prevalence of symptomatic heart failure with reduced and with normal ejection fraction in an elderly general population-the CARLA study

scientific article

Reducing elevated heart rate in patients with multiple organ dysfunction syndrome by the I f (funny channel current) inhibitor ivabradine ⬇️

scientific article published on June 3, 2011

Regional differences in body fat distributions among people with comparable body mass index: a comparison across six German population-based surveys

scientific article

Rehabilitation in Patients With Coronary Heart Disease: Participation and Its Effect on Prognosis

scientific article

Septic cardiomyopathy - A not yet discovered cardiomyopathy?

scientific article

Septic cardiomyopathy: hemodynamic quantification, occurrence, and prognostic implications

scientific article

Serum Thyrotropin Concentrations Are Not Associated with the Ankle-Brachial Index: Results from Three Population-Based Studies

scientific article

Severity of cardiac impairment in the early stage of community-acquired sepsis determines worse prognosis

scientific article

Staphylococcus aureus α-Toxin Triggers the Synthesis of B-Cell Lymphoma 3 by Human Platelets ⬇️

scientific article published on January 28, 2011

Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures

scientific article

The ICM research agenda on extracorporeal life support

scientific article

The alteration of autonomic function in multiple organ dysfunction syndrome

scientific article

The enhanced plasma levels of soluble tumor necrosis factor receptors (sTNF-R1; sTNF-R2) and interleukin-10 (IL-10) in patients suffering from chronic heart failure are reversed in patients treated with beta-adrenoceptor antagonist

scientific article

Transesophageal echocardiographic image of a thrombus crossing a persistent foramen ovale from the right into the left atrium

scientific article

Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanisms

scientific article

List of works by Karl Werdan

Advances in the management of heart failure: the role of ivabradine

Altered interleukin-1 receptor antagonist and interleukin-18 mRNA expression in myocardial tissues of patients with dilatated cardiomyopathy

Anticoagulation in atrial fibrillation: NOAC's the word

Apoptosis contributes to septic cardiomyopathy and is improved by simvastatin therapy

Association between autonomic nervous dysfunction and cellular inflammation in end-stage renal disease

Association of Serum Thyrotropin with Anthropometric Markers of Obesity in the General Population

Association of childhood and adult socioeconomic indicators with cardiovascular risk factors and its modification by age: the CARLA Study 2002-2006 ⬇️

Association of health behaviour with heart rate variability: a population-based study

Association of statin therapy and increased survival in patients with multiple organ dysfunction syndrome

Atypical course of a persistent left superior vena cava through the left atrium ⬇️

C-reactive protein levels and genetic variants of CRP as prognostic markers for combined cardiovascular endpoint (cardiovascular death, death from stroke, myocardial infarction, and stroke/TIA).

Cardiogenic shock due to myocardial infarction: diagnosis, monitoring and treatment: a German-Austrian S3 Guideline

Cardiovascular disease, risk factors and heart rate variability in the elderly general population: design and objectives of the CARdiovascular disease, Living and Ageing in Halle (CARLA) Study

Cardiovascular diseases, risk factors and short-term heart rate variability in an elderly general population: the CARLA study 2002-2006.

Changes of individual perception in psychosocial stressors related to German reunification in 1989/1990 and cardiovascular risk factors and cardiovascular diseases in a population-based study in East Germany

Chemo- and ergoreflexes in health, disease and ageing

Concept for a study design in patients with severe community-acquired pneumonia: A randomised controlled trial with a novel IGM-enriched immunoglobulin preparation - The CIGMA study

Contribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis

Different treatment options in chronic coronary artery disease: when is it the time for medical treatment, percutaneous coronary intervention or aortocoronary bypass surgery?

Direct inhibition, but indirect sensitization of pacemaker activity to sympathetic tone by the interaction of endotoxin with HCN-channels

Directed expression of dominant-negative p73 enables proliferation of cardiomyocytes in mice

Drug-eluting stents versus bare-metal stents in acute myocardial infarction with cardiogenic shock

Effect of inflammatory mediators on cardiovascular function

Effectiveness of Ivabradine Treatment in Different Subpopulations with Stable Angina in Clinical Practice: A Pooled Analysis of Observational Studies

Effects of aprotinin on gene expression and protein synthesis after ischemia and reperfusion in rats

Efficacy of enoxaparin, certoparin and dalteparin in preventing cardiac catheter thrombosis: an in vitro approach

Embolic events caused by aortic thrombi: An underestimated entity? ⬇️

Endotoxin-activated cultured neonatal rat cardiomyocytes express functional surface-associated interleukin-1alpha

Extracorporeal life support during cardiac arrest and cardiogenic shock-how good is the evidence really?

Further evaluation of plasma sphingomyelin levels as a risk factor for coronary artery disease

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data

Heart rate as an independent risk factor in patients with multiple organ dysfunction: a prospective, observational study ⬇️

Impaired chemoreflex sensitivity in adult patients with multiple organ dysfunction syndrome--the potential role of disease severity

Impaired regulation of cardiac function in sepsis, SIRS, and MODS.

Impedance cardiography: a useful and reliable tool in optimization of cardiac resynchronization devices

In vitro comparison of dabigatran, unfractionated heparin, and low-molecular-weight heparin in preventing thrombus formation on mechanical heart valves

Inhibition of cardiac pacemaker channel hHCN2 depends on intercalation of lipopolysaccharide into channel-containing membrane microdomains

Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome

Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome

Interaction of vascular smooth muscle cells and monocytes by soluble factors synergistically enhances IL-6 and MCP-1 production

Interleukin-1 potently contributes to 25-hydroxycholesterol-induced synergistic cytokine production in smooth muscle cell-monocyte interactions

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

Is external defibrillation an electric threat for bystanders?

Ivabradine in Combination with Metoprolol Improves Symptoms and Quality of Life in Patients with Stable Angina Pectoris: A post hoc Analysis from the ADDITIONS Trial

Ivabradine in combination with Beta-blockers in patients with chronic stable angina after percutaneous coronary intervention

Ivabradine in combination with beta-blocker improves symptoms and quality of life in patients with stable angina pectoris: results from the ADDITIONS study

Mechanical circulatory support in cardiogenic shock

Mechanisms of infective endocarditis: pathogen-host interaction and risk states

Mitochondrial dysfunction in sepsis: evidence from bacteraemic baboons and endotoxaemic rabbits

Neutrophils process interleukin-1beta and interleukin-18 precursors in a caspase-1-like fashion--processing is inhibited by human vascular smooth muscle cells.

Non-compaction cardiomyopathy with diffuse left coronary artery fistulae as a rare cause of congestive heart failure ⬇️

Performance of Sokolow-Lyon index in detection of echocardiographically diagnosed left ventricular hypertrophy in a normal Eastern German population - results of the CARLA study

Periodontal conditions and incidence of new cardiovascular events among patients with coronary vascular disease

Prevalence of symptomatic heart failure with reduced and with normal ejection fraction in an elderly general population-the CARLA study

Reducing elevated heart rate in patients with multiple organ dysfunction syndrome by the I f (funny channel current) inhibitor ivabradine ⬇️

Regional differences in body fat distributions among people with comparable body mass index: a comparison across six German population-based surveys

Rehabilitation in Patients With Coronary Heart Disease: Participation and Its Effect on Prognosis

Septic cardiomyopathy - A not yet discovered cardiomyopathy?

Septic cardiomyopathy: hemodynamic quantification, occurrence, and prognostic implications

Serum Thyrotropin Concentrations Are Not Associated with the Ankle-Brachial Index: Results from Three Population-Based Studies

Severity of cardiac impairment in the early stage of community-acquired sepsis determines worse prognosis

Staphylococcus aureus α-Toxin Triggers the Synthesis of B-Cell Lymphoma 3 by Human Platelets ⬇️

Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures

The ICM research agenda on extracorporeal life support

The alteration of autonomic function in multiple organ dysfunction syndrome

The enhanced plasma levels of soluble tumor necrosis factor receptors (sTNF-R1; sTNF-R2) and interleukin-10 (IL-10) in patients suffering from chronic heart failure are reversed in patients treated with beta-adrenoceptor antagonist

Transesophageal echocardiographic image of a thrombus crossing a persistent foramen ovale from the right into the left atrium

Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanisms