List of works by Angus W. Thomson

"Alternatively activated" dendritic cells preferentially secrete IL-10, expand Foxp3+CD4+ T cells, and induce long-term organ allograft survival in combination with CTLA4-Ig

scientific article published on 01 November 2006

A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells.

scientific article published on 11 July 2016

A Tale of Two Pathways: Renewing the Promise of Anti-CD40L Blockade

scientific article published on 31 January 2017

A simplified method for growing dendritic cells from rat bone marrow

scientific article published on 01 January 1995

A toxicological study in rats receiving immunotherapeutic doses of cyclosporin A

scientific article published on 01 February 1981

Abstract

Abstract 102: inflammatory mediators modulate alloreactive T cell susceptibility to immune-regulation in reconstructive transplantation

scientific article published on 01 March 2014

Activation of parenchymal CD47 promotes renal ischemia-reperfusion injury

scientific article

Adenoviral delivery of CTLA4Ig into myeloid dendritic cells promotes their in vitro tolerogenicity and survival in allogeneic recipients

scientific article published in April 1999

All-trans retinoic acid and rapamycin synergize with transforming growth factor-β1 to induce regulatory T cells but confer different migratory capacities

scientific article published on 29 July 2013

Alleviation of cyclosporin-induced immune suppression by the cytokine inducer ADA-202-718

scientific article published on 01 March 1989

Alleviation of experimental cyclosporin A toxicity by substitution of fish muscle oil as drug vehicle

scientific article published on 01 July 1990

Alloantigen presentation by ethylcarbodiimide-treated dendritic cells induces T cell hyporesponsiveness, and prolongs organ graft survival ⬇️

scientific article published on September 1, 2003

Allospecific CD154+ T cells associate with rejection risk after pediatric liver transplantation

scientific article

Allostimulatory activity of bone marrow-derived plasmacytoid dendritic cells is independent of indoleamine dioxygenase but regulated by inducible costimulator ligand expression

scientific article published on 03 February 2009

Amelioration of cyclosporin-induced nephrotoxicity in rats by induction of hepatic drug metabolism

scientific article published on 01 February 1985

Anti-inflammatory agents in allergic diseases

scientific article published on 01 October 1995

Antigen presentation and HLA-DR expression by FK-506-treated human monocytes ⬇️

scientific article published on December 1, 1990

Apoptosis of graft-infiltrating cytotoxic T cells: a mechanism underlying "split tolerance" in mouse liver transplantation

scientific article published on February 1997

Apoptosis within spontaneously accepted mouse liver allografts: evidence for deletion of cytotoxic T cells and implications for tolerance induction

scientific article

Aspirin inhibits in vitro maturation and in vivo immunostimulatory function of murine myeloid dendritic cells

scientific article (publication date: 15 June 2001)

Aspirin promotes kidney allograft survival and function

scientific article (publication date: 27 January 2005)

Augmentation of type-1 polarizing ability of monocyte-derived dendritic cells from chronically immunosuppressed organ-transplant recipients.

scientific article published on February 2005

Blockade of the CD40-CD40 ligand pathway potentiates the capacity of donor-derived dendritic cell progenitors to induce long-term cardiac allograft survival

scientific article published on 01 December 1997

Blocking of the B7-CD28 Pathway Increases the Capacity of FasL+ (CD95L+) Dendritic Cells to Kill Alloactivated T Cells ⬇️

scientific article published on January 1, 1997

Blocking of the B7-CD28 pathway increases apoptosis induced in activated T cells by in vitro-generated CD95L (FasL) positive dendritic cells

scientific article

Blood lymphocytes of autoimmune disease patients receiving FK506 exhibit normal ex vivo cytokine gene expression and proliferative responses

scientific article published on 01 November 1993

Bone marrow-derived dendritic cell progenitors (NLDC 145+, MHC class II+, B7-1dim, B7-2-) induce alloantigen-specific hyporesponsiveness in murine T lymphocytes

scientific article

Brequinar sodium inhibits interleukin-6-induced differentiation of a human B-cell line into IgM-secreting plasma cells.

scientific article published on August 1993

CCR and CC chemokine expression in relation to Flt3 ligand-induced renal dendritic cell mobilization

scientific article published on 01 November 2004

CD39 deficiency in murine liver allografts promotes inflammatory injury and immune-mediated rejection

scientific article

CD39 expression by hepatic myeloid dendritic cells attenuates inflammation in liver transplant ischemia-reperfusion injury in mice

scientific article published on 15 October 2013

CD4+ T cell responses elicited by different subsets of human skin migratory dendritic cells.

scientific article published in December 2005

CD47 regulates renal tubular epithelial cell self-renewal and proliferation following renal ischemia reperfusion

scientific article published on 31 May 2016

CD8alpha(+) (lymphoid-related) and CD8alpha(-) (myeloid) dendritic cells differentially regulate vascularized organ allograft survival

scientific article published on 01 February 2001

CTLA4-Ig inhibits rejection of mouse liver allografts from Flt3-ligand-treated donors and is associated with increased lymphocyte apoptosis

CXCL9 antagonism further extends prolonged cardiac allograft survival in CCL19/CCL21-deficient mice

scientific article published in September 2005

Characterization of eomesodermin and T-bet expression by allostimulated CD8 T cells of healthy volunteers and kidney transplant patients in relation to graft outcome

scientific article published on 23 September 2018

Chimerism after organ transplantation

scientific article

Chimerism after whole organ transplantation: its relationship to graft rejection and tolerance induction.

scientific article published on November 1994

Chimerism and xenotransplantation. New concepts

scientific article

Chronic ethanol exposure affects in vivo migration of hepatic dendritic cells to secondary lymphoid tissue

scientific article published on 11 April 2007

Circulating ICAM-1, E-selectin, IL-2 receptor, and HLA class I in human small bowel, liver, and small bowel-plus-liver transplant recipients

scientific article published on 01 September 1995

Circulating intercellular adhesion molecule-1 (ICAM-1) in autoimmune liver disease and evidence for the production of ICAM-1 by cytokine-stimulated human hepatocytes

scientific article

Clinical tolerance following liver transplantation: long term results and future prospects.

scientific article published on 17 October 2006

Combined Administration of a Mutant TGF-β1/Fc and Rapamycin Promotes Induction of Regulatory T Cells and Islet Allograft Tolerance ⬇️

scientific article published on September 15, 2010

Combined effects of FK506 (tacrolimus) and cyclophosphamide on atypical B220+ T cells, cytokine gene expression and disease activity in MRL/MpJ-lpr/lpr mice

scientific article published on 01 April 1995

Comparative analysis of dendritic cell density and total number in commonly transplanted organs: morphometric estimation in normal mice

scientific article published on 01 March 2000

Comparative analysis of the fate of donor dendritic cells and B cells and their influence on alloreactive T cell responses under tacrolimus immunosuppression

scientific article published in February 2005

Comparative evaluation of CC chemokine-induced migration of murine CD8α+ and CD8α− dendritic cells and their in vivo trafficking ⬇️

scientific article published on 03 November 2003

Computer-guided concentration-controlled trials in autoimmune disorders

scientific article published on 01 December 1993

Contrasting effects of myeloid dendritic cells transduced with an adenoviral vector encoding interleukin-10 on organ allograft and tumour rejection

Controlled release formulations of IL-2, TGF-β1 and rapamycin for the induction of regulatory T cells.

scientific article published on 21 January 2012

Costimulation blockade promotes the apoptotic death of graft-infiltrating T cells and prolongs survival of hepatic allografts from FLT3L-treated donors

scientific article published on 01 October 2001

Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80dim, CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients

scientific article

Costimulatory molecule-deficient dendritic cell progenitors induce T cell hyporesponsiveness in vitro and prolong the survival of vascularized cardiac allografts

scientific article published on February 1997

Cutting edge: Flt3 ligand mediates STAT3-independent expansion but STAT3-dependent activation of myeloid-derived suppressor cells.

scientific article published on 17 March 2014

Cyclosporin A-induced nephrotoxicity in the rat: relationship to increased plasma renin activity

scientific article published on 01 June 1987

Cyclosporin A: immune suppressant and antiparasitic agent

scientific article published on 01 October 1986

Cyclosporin and skin disease

scientific article published on 01 January 1985

Cytidine potentiates the inhibitory effect of brequinar sodium on xeno-MLR, antibody production, and concordant hamster to rat cardiac xenograft survival.

scientific article published on November 1993

Cytokine gene expression in murine lymphocytes activated in the presence of FK 506, bredinin, mycophenolic acid, or brequinar sodium ⬇️

scientific article published on December 1, 1992

Cytokine gene polymorphisms in children successfully withdrawn from immunosuppression after liver transplantation

scientific article published on 01 April 2002

Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation

scientific article published on 01 September 2001

DAP12 promotes IRAK-M expression and IL-10 production by liver myeloid dendritic cells and restrains their T cell allostimulatory ability.

scientific article published on 21 January 2011

DAP12/TREM2 Expression by Mouse and Human Liver DC: Functional Implications and Regulation of Liver Ischemia-Reperfusion Injury

scientific article published on 19 February 2019

Dendritic Cells as Sensors, Mediators, and Regulators of Ischemic Injury

scientific article published on 15 October 2019

Dendritic cell immunobiology in relation to liver transplant outcome.

scientific article published on June 2009

Dendritic cell subset ratio in peripheral blood correlates with successful withdrawal of immunosuppression in liver transplant patients

scientific article published on 01 June 2003

Dendritic cell subset ratio in tolerant, weaning and non-tolerant liver recipients is not affected by extent of immunosuppression

scientific article published in February 2005

Dendritic cells and chemokine-directed migration in transplantation: where are we headed?

scientific article published on September 2008

Dendritic cells and regulation of alloimmune responses: relevance to outcome and therapy of organ transplantation

scientific article published in September 2005

Dendritic cells and regulation of graft-versus-host disease and graft-versus-leukemia activity

scientific article

Dendritic cells and tolerance induction.

scientific article published on September 1996

Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-associated increases in CD11c+ cells in adipose tissue and liver

scientific article

Dendritic cells, the liver, and transplantation

scientific article published on December 2007

Dendritic cells: emerging pharmacological targets of immunosuppressive drugs

scientific article published on January 2004

Dendritic cells: regulators of alloimmunity and opportunities for tolerance induction ⬇️

scientific article published on December 1, 2003

Dexamethasone preferentially suppresses plasmacytoid dendritic cell differentiation and enhances their apoptotic death

scientific article published on 05 December 2005

Differential effects of exogenous interleukin-10 on cardiac allograft survival: inhibition of rejection by recipient pretreatment reflects impaired host accessory cell function

scientific article published on 01 November 1999

Differential modulation of CD4 and CD8 T-cell proliferation by induction of nitric oxide synthesis in antigen presenting cells

scientific article published on 01 September 2002

Differential regulation of T-cell proliferation and apoptosis by hepatic CD8alpha(+) (lymphoid-related) and CD8alpha(-) (myeloid) dendritic cells

scientific article published on 01 February 2001

Disparate ability of murine CD8alpha- and CD8alpha+ dendritic cell subsets to traverse endothelium is not determined by differential CD11b expression

scientific article published on 01 November 2004

Donor bone marrow potentiates the effect of tacrolimus on nonvascularized heart allograft survival: association with microchimerism and growth of donor dendritic cell progenitors from recipient bone marrow

scientific article published on 01 February 1998

Donor cell chimerism permitted by immunosuppressive drugs: a new view of organ transplantation

scientific article

Donor cell chimerism permitted by immunosuppressive drugs: a new view of organ transplantation

scientific article published on 01 May 1993

Donor plasmacytoid dendritic cells modulate effector and regulatory T cell responses in mouse spontaneous liver transplant tolerance

scientific article published on 28 November 2020

Donor pretreatment with Flt-3 ligand augments antidonor cytotoxic T lymphocyte, natural killer, and lymphokine-activated killer cell activities within liver allografts and alters the pattern of intragraft apoptotic activity

scientific article published on June 1998

Donor-Derived Regulatory Dendritic Cell Infusion Maintains Donor-Reactive CD4+CTLA4hi T Cells in Non-Human Primate Renal Allograft Recipients Treated with CD28 Co-Stimulation Blockade.

scientific article published on 19 February 2018

Donor-derived regulatory dendritic cell infusion results in host cell cross-dressing and T cell subset changes in prospective living donor liver transplant recipients

scientific article published on 10 November 2020

Donor-recipient microchimerism and tolerance induction

scientific article published on 01 January 1996

E-selectin and interleukin-2 receptor alpha-chain expression in alopecia universalis

scientific article published on 01 January 1994

EBV-specific CD8+ T cell reactivation in transplant patients results in expansion of CD8+ type-1 regulatory T cells

scientific article published on 27 February 2007

Effect in supralethally irradiated rats of granulocyte colony-stimulating factor and lisofylline on hematopoietic reconstitution by syngeneic bone marrow or whole organ passenger leukocytes ⬇️

scientific article published on June 27, 1997

Effects of FK 506 and low concentration cyclosporine on human lymphocyte activation antigen expression: a flow cytometric analysis

scientific article published on 01 August 1990

Effects of FK 506, mycophenolic acid, and bredinin on OKT-3-, PMA-, and alloantigen-induced activation molecule expression on cultured CD4+ and CD8+ human lymphocytes

scientific article published on 01 December 1991

Effects of combined administration of FK 506 and the purine biosynthesis inhibitors mizoribine or mycophenolic acid on lymphocyte DNA synthesis and T cell activation molecule expression in human mixed lymphocyte cultures ⬇️

scientific article published on January 1, 1993

Effects of cyclosporin A on fetal development in the rat

Effects of liver-derived dendritic cell progenitors on Th1- and Th2-like cytokine responses in vitro and in vivo

scientific article published on 01 February 2000

Efficacy of FK 506 in the treatment of recalcitrant pyoderma gangrenosum ⬇️

scientific article published on December 1, 1991

Elevated myeloid: plasmacytoid dendritic cell ratio associates with early acute cellular rejection in pediatric small bowel transplantation

scientific article published in January 2010

Elevated myeloid: plasmacytoid dendritic cell ratio associates with late, but not early, liver rejection in children induced with rabbit anti-human thymocyte globulin

scientific article published on August 2009

Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells

scientific article published on 29 July 2004

Endotoxin modulates the capacity of CpG-activated liver myeloid DC to direct Th1-type responses

scientific article published on 01 September 2006

Enhancement of dendritic cell tolerogenicity by genetic modification using adenoviral vectors encoding cDNA for TGF beta 1

Enhancement of high dose cyclosporin A toxicity by frusemide

scientific article published on 01 April 1984

Erratum: Hepatic Dendritic Cells, the Tolerogenic Liver Environment, and Liver Disease

scientific article published on 24 July 2018

Ethanol affects the generation, cosignaling molecule expression, and function of plasmacytoid and myeloid dendritic cell subsets in vitro and in vivo

scientific article published on 14 February 2006

Evaluation of the influence of FK 506, rapamycin, and cyclosporine on processing and presentation of particulate antigen by macrophages: assessment of a drug "carry-over" effect ⬇️

scientific article published on December 1, 1991

Evidence for a role of IL-17 in alloimmunity: a novel IL-17 antagonist promotes heart graft survival

scientific article published on 01 February 1999

Evidence that FK 506 may abrogate suppressor cell activity induced by blood transfusion

scientific article published on 01 December 1991

Exposure to type-I collagen induces maturation of mouse liver dendritic cell progenitors

scientific article published on 01 January 1995

FK 506 and autoimmune disease: perspective and prospects ⬇️

scientific article published on January 1, 1992

FK 506 inhibits cytokine gene and adhesion molecule expression in psoriatic skin lesions

scientific article published on 01 November 1993

FK 506 treatment following syngeneic bone marrow transplantation does not inhibit clonal deletion of V beta 5+ or V beta 11+ T cells

scientific article published on 01 December 1992

FK 506, cardiac transplantation, and graft-vessel disease

scientific article published on January 25, 1992

FK 506: a novel immunosuppressant for treatment of autoimmune disease. Rationale and preliminary clinical experience at the University of Pittsburgh

scientific article

FK506 inhibits the differentiation of developing thymocytes but not negative selection of T cell receptor Vβ5+ and Vβ;11+ T lymphocytes in vivo ⬇️

scientific article published on 01 January 1994

FK506--its influence on anti-class 1 MHC alloantibody responses to blood transfusions ⬇️

scientific article published on 01 August 1990

Feasibility of CTLA4Ig gene delivery and expression in vivo using retrovirally transduced myeloid dendritic cells that induce alloantigen-specific T cell anergy in vitro

scientific article published in August 2000

Flow cytometric analysis of lymphocyte populations and activation antigen expression in blood and lymphoid tissues of FK 506-treated rats

scientific article published on 01 August 1990

Frontiers of immunological tolerance

scientific article published on January 2007

Functional modification of CD11c+ liver dendritic cells during liver regeneration after partial hepatectomy in mice

scientific article published on 01 April 2006

Fundamental Ca2+ signaling mechanisms in mouse dendritic cells: CRAC is the major Ca2+ entry pathway.

scientific article

Galectin-1, immune regulation and liver allograft survival

scientific article published in March 2013

Gene therapy strategies to prevent autoimmune disorders

scientific article

Generation and functional assessment of nonhuman primate regulatory dendritic cells and their therapeutic efficacy in renal transplantation

scientific article published on 12 March 2020

Generation of DC from mouse spleen cell cultures in response to GM-CSF: immunophenotypic and functional analyses

article

Generation of Nitric Oxide by Mouse Dendritic Cells and Its Implications for Immune Response Regulation ⬇️

scientific article published on 01 January 1997

Genetic engineering of dendritic cells to express immunosuppressive molecules (viral IL-10, TGF-beta, and CTLA4Ig).

scientific article

Graft hyporeactivity induced by donor-derived dendritic cell progenitors

scientific article published on 01 March 2000

Graft-infiltrating PD-L1(hi) cross-dressed dendritic cells regulate anti-donor T cell responses in mouse liver transplant tolerance

scientific article published on 16 September 2017

Granulocyte/macrophage colony-stimulating factor-stimulated hepatic dendritic cell progenitors prolong pancreatic islet allograft survival.

scientific article

Growth of donor-derived dendritic cells from the bone marrow of murine liver allograft recipients in response to granulocyte/macrophage colony-stimulating factor

scientific article

HLA-G level on monocytoid dendritic cells correlates with regulatory T-cell Foxp3 expression in liver transplant tolerance

scientific article

Heart allograft protection with low-dose carbon monoxide inhalation: effects on inflammatory mediators and alloreactive T-cell responses

scientific article published on 01 January 2006

Heart, but not skin, allografts from donors lacking Flt3 ligand exhibit markedly prolonged survival time

scientific article

Hepatic B cells are readily activated by Toll-like receptor-4 ligation and secrete less interleukin-10 than lymphoid tissue B cells

scientific article published in September 2013

Hepatic B7 homolog 1 expression is essential for controlling cold ischemia/reperfusion injury after mouse liver transplantation

scientific article

Hepatic Dendritic Cells, the Tolerogenic Liver Environment, and Liver Disease

scientific article published on 01 May 2018

Hepatic antigen-presenting cells and regulation of liver transplant outcome

scientific article published on 01 August 2011

Hepatocytes and liver nonparenchymal cells induce apoptosis in activated T cells

scientific article published on 01 February 1999

High PD-L1/CD86 MFI ratio and IL-10 secretion characterize human regulatory dendritic cells generated for clinical testing in organ transplantation

scientific article published on 14 September 2017

High PD-L1/CD86 ratio on plasmacytoid dendritic cells correlates with elevated T-regulatory cells in liver transplant tolerance

scientific article

High-dose cellular IL-10 exacerbates rejection and reverses effects of cyclosporine and tacrolimus in Mouse cardiac transplantation

scientific article published on 01 February 1997

Highlights of the Festschrift in honor of Thomas E. Starzl, MD, PHD

scientific article published on 01 January 2002

Highly efficient expression of transgenic proteins by naked DNA-transfected dendritic cells through terminal differentiation ⬇️

scientific article published on October 9, 2003

Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo

scientific article published on 25 October 2011

Hosts lacking fms-like tyrosine kinase 3 ligand exhibit marked reductions in transplant vascular sclerosis.

scientific article

IL-12hi rapamycin-conditioned dendritic cells mediate IFN-γ-dependent apoptosis of alloreactive CD4+ T cells in vitro and reduce lethal graft-versus-host disease.

scientific article

IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells

scientific article

IL-27 production and STAT3-dependent upregulation of B7-H1 mediate immune regulatory functions of liver plasmacytoid dendritic cells

scientific article published on 16 April 2012

IL-33 broadens its repertoire to affect DC.

scientific article

IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.

scientific article

IL-33-mediated IL-13 secretion by ST2+ Tregs controls inflammation after lung injury

scientific article published on 21 March 2019

IL-8/IL-8 receptor expression in psoriasis and the response to systemic tacrolimus (FK506) therapy

scientific article published on 01 February 1995

IRF-1 promotes liver transplant ischemia/reperfusion injury via hepatocyte IL-15/IL-15Rα production

scientific article published on 11 May 2015

Identification and characterization of intestinal Peyer's patch interferon-alpha producing (plasmacytoid) dendritic cells

scientific article published in February 2004

Identification of donor-derived dendritic cell progenitors in bone marrow of spontaneously tolerant liver allograft recipients

scientific article

Identity Crisis

scientific article published on 01 February 2016

Il-12 antagonism enhances apoptotic death of T cells within hepatic allografts from Flt3 ligand-treated donors and promotes graft acceptance

scientific article published on 01 May 2001

Immature and mature CD8alpha+ dendritic cells prolong the survival of vascularized heart allografts

scientific article published on 01 January 2002

Immunity and tolerance are related, and governed by antigen migration and localization

scientific article

Immunomodulation of psoriasis with a topical cyclosporin A formulation

scientific article published on 01 April 1993

Immunophenotypic analysis of blood and spleen lymphocyte subsets in rats protected against schistosomiasis by cyclosporin A

scientific article published on 01 February 1988

Immunoregulatory functions of mTOR inhibition.

scientific article

Immunoregulatory properties of rapamycin-conditioned monocyte-derived dendritic cells and their role in transplantation

scientific article published on 28 September 2012

Immunosuppressive activity and toxicity of cyclosporin A in rats pretreated with high dose cyclophosphamide

scientific article published in October 1985

Immunosuppressive activity of FK-506 in rats: flow cytometric analysis of lymphocyte populations in blood, spleen and thymus during treatment and following drug withdrawal ⬇️

scientific article published on 01 January 1990

Immunosuppressive activity, lymphocyte subset analysis, and acute toxicity of FK-506 in the rat. A comparative and combination study with cyclosporine

scientific article published on 01 January 1989

Immunosuppressive agents: recent developments in molecular action and clinical application

scientific article published on 01 June 1998

Immunosuppressive properties of FK-506 and rapamycin

scientific article published on 01 August 1989

Impact of Flt-3 ligand on donor-derived antigen presenting cells and alloimmune reactivity in heart graft recipients given adjuvant donor bone marrow

scientific article published on 01 December 1998

Impact of Human Mutant TGFβ1/Fc Protein on Memory and Regulatory T Cell Homeostasis Following Lymphodepletion in Nonhuman Primates

scientific article published on 23 May 2016

Impact of donor MHC class I or class II antigen deficiency on first- and second-set rejection of mouse heart or liver allografts

scientific article published on 01 May 1996

In situ recruitment of regulatory T cells promotes donor-specific tolerance in vascularized composite allotransplantation

scientific article published on 13 March 2020

In vitro propagation and homing of liver-derived dendritic cell progenitors to lymphoid tissues of allogeneic recipients. Implications for the establishment and maintenance of donor cell chimerism following liver transplantation

scientific article

In vivo-mobilized kidney dendritic cells are functionally immature, subvert alloreactive T-cell responses, and prolong organ allograft survival

scientific article

Incidence of CD4+ IL-2R alpha+ and CD4+ CD45RA+ T-cells in progressive multiple sclerosis and the influence of short-term (3 months) FK 506 therapy

scientific article published on 01 November 1993

Increased apoptosis of immunoreactive host cells and augmented donor leukocyte chimerism, not sustained inhibition of B7 molecule expression are associated with prolonged cardiac allograft survival in mice preconditioned with immature donor dendriti

scientific article

Induced regulatory T cells: mechanisms of conversion and suppressive potential

scientific article

Influence of FK 506 on T lymphocytes, Langerhans' cells and the expression of cytokine receptors and adhesion molecules in psoriatic skin lesions: a preliminary study ⬇️

scientific article published on December 1, 1991

Influence of FK506 and cyclosporin A on alloantibody production and lymphocyte activation following blood transfusion ⬇️

scientific article published on 01 December 1990

Influence of cyclosporin A and alpha-difluoromethylornithine, an inhibitor of polyamine biosynthesis, on two rodent T-cell cancers in vivo

scientific article published on 01 December 1989

Influence of cyclosporin A on growth of an acute T-cell leukaemia in PVG rats

scientific article published on 01 June 1988

Influence of immunosuppressive drugs on dendritic cells

scientific article

Influence of the hepatic drug-metabolizing enzyme-inducer phenobarbitone on cyclosporine nephrotoxicity and hepatotoxicity in renal-allografted rats

scientific article published on 01 April 1988

Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques

scientific article published in July 2007

Inhibition by cyclosporin A of IgE production and cyclophosphamide-induced eosinophilia in rats immunized with non-parasite antigens

scientific article published on 01 January 1985

Inhibition of T lymphocyte activation and apoptotic cell death by cyclosporin A and tacrolimus (FK506). Its relevance to therapy of HIV infection.

scientific article

Inhibition of drug-induced eosinophilia by cyclosporin A

scientific article published on 01 August 1986

Inhibition of the allograft response by donor specific blood transfusion: association with reduced local TH1 cytokines and nitric oxide but enhanced prostaglandin E2 production

scientific article published on 01 December 2000

Inhibitory effect of FK 506 on autoimmune thyroid disease in the PVG rat

scientific article published on 01 November 1993

Interleukin-17 antagonism inhibits acute but not chronic vascular rejection

scientific article published on 01 July 2001

Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production.

scientific article published on 5 September 2002

Intratumoral delivery of mTORC2-deficient dendritic cells inhibits B16 melanoma growth by promoting CD8(+) effector T cell responses

scientific article published on 23 March 2016

Intrinsic ability of GM+IL-4 but not Flt3L-induced rat dendritic cells to promote allogeneic T cell hyporesponsiveness

scientific article published on 05 February 2007

Isolation of dendritic leukocytes from mouse liver

scientific article published on 01 January 1995

Isolation, phenotype, and allostimulatory activity of mouse liver dendritic cells

scientific article

Kinetics of early T-cell repopulation in the mouse following syngeneic bone marrow transplantation: FK 506 causes a maturational defect of CD4+ CD8- T cells

scientific article published on 01 December 1991

Leukocyte procoagulant activity as an in vitro index of nickel contact hypersensitivity

scientific article published on 01 January 1985

Liver transplant recipients weaned off immunosuppression lack circulating donor-specific antibodies

scientific article published on 23 December 2009

Liver transplantation in the mouse: Insights into liver immunobiology, tissue injury, and allograft tolerance

scientific article published on 28 December 2015

Liver transplants contribute to their own success

scientific article published on February 1996

Location, location, location: dendritic cell trafficking and transplant tolerance

scientific article published on February 2007

Low TLR4 expression by liver dendritic cells correlates with reduced capacity to activate allogeneic T cells in response to endotoxin

scientific article published on 01 February 2005

Low-dose FK 506 inhibits sensitisation after blood transfusions

scientific article published on 01 August 1990

Mammalian and viral IL-10 enhance C-C chemokine receptor 5 but down-regulate C-C chemokine receptor 7 expression by myeloid dendritic cells: impact on chemotactic responses and in vivo homing ability

scientific article published on 01 June 2001

Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients

scientific article

Manipulation of dendritic cells as an approach to improved outcomes in transplantation.

scientific article published on 18 February 2002

Manipulation of dendritic cells for tolerance induction in transplantation and autoimmune disease

scientific article

Marked inhibition of transplant vascular sclerosis by in vivo-mobilized donor dendritic cells and anti-CD154 mAb.

scientific article published in August 2003

Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-kappa B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig

scientific article

Metabolic effects of FK 506 in patients with severe psoriasis: short-term follow-up of seven cases ⬇️

scientific article published on December 1, 1991

Microchimerism, dendritic cell progenitors and transplantation tolerance

scientific article

Microchimerism, donor dendritic cells, and alloimmune reactivity in recipients of Flt3 ligand-mobilized hemopoietic cells: modulation by tacrolimus

scientific article published on 01 July 2000

Migratory responses of murine hepatic myeloid, lymphoid-related, and plasmacytoid dendritic cells to CC chemokines

scientific article published on 01 September 2004

Mode of action of tacrolimus (FK506): molecular and cellular mechanisms.

scientific article published on December 1995

Molecular regulation of hepatic dendritic cell function and its relation to liver transplant outcome

scientific article published on August 2009

Monitoring of human liver and kidney allograft tolerance: a tissue/histopathology perspective

scientific article published on 26 September 2008

Monitoring the operationally tolerant liver allograft recipient.

scientific article published on February 2010

Monitoring the patient off immunosuppression. Conceptual framework for a proposed tolerance assay study in liver transplant recipients.

scientific article

Monocytic myeloid-derived suppressor cells generated from rhesus macaque bone marrow enrich for regulatory T cells

scientific article published on 27 April 2018

Multilineage hematopoietic reconstitution of supralethally irradiated rats by syngeneic whole organ transplantation. With oarticular reference to the liver

scientific article

Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction

scientific article published on 26 February 2013

NOD2 ligation subverts IFN-alpha production by liver plasmacytoid dendritic cells and inhibits their T cell allostimulatory activity via B7-H1 up-regulation.

scientific article

Naturally occurring regulatory T cells: recent insights in health and disease

scientific article published on January 2007

Nephrotoxicity of cyclosporin G in rats

scientific article published on 01 November 1985

Neutralization of IL-12 reverses rejection of mouse liver allografts from Flt3-ligand-treated donors and is associated with suppression of both cellular and humoral responses

scientific article published on 01 February 2001

New immunosuppressive drugs: mechanistic insights and potential therapeutic advances

scientific article

New insights into mechanisms of spontaneous liver transplant tolerance: the role of Foxp3-expressing CD25+CD4+ regulatory T cells.

scientific article

Nitric oxide production by dendritic cells is associated with impairment of T cell responses

scientific article published on 01 February 1997

Nitric oxide production by mouse bone marrow-derived dendritic cells: implications for the regulation of allogeneic T cell responses

scientific article published on 01 December 1996

Orchestration of transplantation tolerance by regulatory dendritic cell therapy or in-situ targeting of dendritic cells

scientific article

Orthotopic mouse liver transplantation to study liver biology and allograft tolerance.

scientific article

Paradoxical augmentation of tuberculin-like hypersensitivity, but not Jones-Mote or contact hypersensitivity, in cyclosporin A treated guinea pigs

scientific article published on 01 January 1986

Pathological changes developing in the rat during a 3-week course of high dosage cyclosporin A and their reversal following drug withdrawal ⬇️

scientific article published on 01 October 1981

Pharmacological modification of dendritic cells to promote their tolerogenicity in transplantation

scientific article published in January 2010

Phenotypic and functional characterization of mouse hepatic CD8 alpha+ lymphoid-related dendritic cells

scientific article published on 01 July 2000

Plasmacytoid Dendritic Cells and the Spontaneous Acceptance of Kidney Allografts

scientific article published on 01 January 2020

Plasmacytoid dendritic cell precursors induce allogeneic T-cell hyporesponsiveness and prolong heart graft survival

scientific article published on 01 August 2005

Plasmacytoid dendritic cell-derived IFN-α promotes murine liver ischemia/reperfusion injury by induction of hepatocyte IRF-1.

scientific article

Poor allostimulatory function of liver plasmacytoid DC is associated with pro-apoptotic activity, dependent on regulatory T cells

scientific article published on 29 September 2008

Potentiation of the antiproliferative activity of brequinar sodium for murine lymphocytes by exogenous cytidine.

scientific article published on February 1993

Preferential induction of Th1 responses by functionally mature hepatic (CD8alpha- and CD8alpha+) dendritic cells: association with conversion from liver transplant tolerance to acute rejection

scientific article published on 01 June 2000

Preliminary assessment of the feasibility of autologous myeloid-derived suppressor cell infusion in non-human primate kidney transplantation

scientific article published on 19 July 2019

Presensitization by skin grafting from major histocompatibility complex class I or major histocompatibility complex class II deficient mice identifies class I antigens as inducers of allosensitization ⬇️

scientific article published on 01 May 1995

Proinflammatory cytokines and endotoxin stimulate ICAM-1 gene expression and secretion by normal human hepatocytes

scientific article published on 01 August 1994

Prolongation of composite tissue allograft survival by immature recipient dendritic cells pulsed with donor antigen and transient low-dose immunosuppression

scientific article published in January 2008

Promotion of skin graft tolerance across MHC barriers by mobilization of dendritic cells in donor hemopoietic cell infusions

scientific article published on 01 September 2002

Propagation of dendritic cell progenitors from normal mouse liver using granulocyte/macrophage colony-stimulating factor and their maturational development in the presence of type-1 collagen

scientific article

Prophylactic and therapeutic effects of ciclosporin A in murine Schistosomiasis mansoni: studies on bisexual and unisexual infections and the hepatic inflammatory response

scientific article published on 01 January 1988

Prospective Clinical Testing of Regulatory Dendritic Cells in Organ Transplantation

scientific article

Rapamycin inhibits IL-4--induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo

scientific article published on 16 January 2003

Rapamycin inhibits macropinocytosis and mannose receptor-mediated endocytosis by bone marrow-derived dendritic cells

scientific article

Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance

scientific article published on 01 June 2007

Rapamycin-conditioned, alloantigen-pulsed dendritic cells promote indefinite survival of vascularized skin allografts in association with T regulatory cell expansion

scientific article published on 5 November 2007

Rapamycin-conditioned, alloantigen-pulsed myeloid dendritic cells present donor MHC class I/peptide via the semi-direct pathway and inhibit survival of antigen-specific CD8(+) T cells in vitro and in vivo.

scientific article

Rapamycin-treated, alloantigen-pulsed host dendritic cells induce ag-specific T cell regulation and prolong graft survival

scientific article published in February 2005

Rare-event analysis of circulating human dendritic cell subsets and their presumptive mouse counterparts

scientific article published on 01 December 2001

Recipient pretreatment with mammalian IL-10 prolongs mouse cardiac allograft survival by inhibition of anti-donor T cell responses

scientific article published on 01 February 1999

Recombinant adenovirus induces maturation of dendritic cells via an NF-kappaB-dependent pathway

scientific article

Reduction in the circulating pDC1/pDC2 ratio and impaired function of ex vivo-generated DC1 in chronic hepatitis B infection

scientific article published on 01 August 2002

Regeneration and Cell Recruitment in an Improved Heterotopic Auxiliary Partial Liver Transplantation Model in the Rat.

scientific article published in January 2017

Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells.

scientific article

Regulation of immune reactivity and tolerance by antigen migration and localization: with particular reference to allo- and xenotransplantation

scientific article published on 01 June 1999

Regulatory T Cell Infusion Can Enhance Memory T Cell and Alloantibody Responses in Lymphodepleted Nonhuman Primate Heart Allograft Recipients

scientific article published on 23 December 2015

Regulatory dendritic cell infusion prolongs kidney allograft survival in nonhuman primates

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Regulatory dendritic cell therapy in organ transplantation

scientific article published on July 2006

Regulatory dendritic cell therapy: from rodents to clinical application

scientific article

Regulatory dendritic cells for human organ transplantation

scientific article published on 13 May 2019

Regulatory dendritic cells for promotion of liver transplant operational tolerance: Rationale for a clinical trial and accompanying mechanistic studies

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Regulatory dendritic cells: profiling, targeting, and therapeutic application

scientific article published on 01 October 2018

Regulatory myeloid cells in transplantation

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Renal Allograft Survival in Nonhuman Primates Infused With Donor Antigen-Pulsed Autologous Regulatory Dendritic Cells

scientific article published on 23 December 2016

Renal transplantation reverses functional deficiencies in circulating dendritic cell subsets in chronic renal failure patients

scientific article published on 01 January 2006

Retroviral delivery of transforming growth factor-beta1 to myeloid dendritic cells: inhibition of T-cell priming ability and influence on allograft survival

scientific article

Retrovirally transduced myeloid dendritic cells expressing mammalian or viral IL-10 differentially affect cell-mediated immunity and growth of transplantable tumors

scientific article published on 01 February 2001

Rhesus monkey immature monocyte-derived dendritic cells generate alloantigen-specific regulatory T cells from circulating CD4+CD127-/lo T cells

scientific article

Rictor deficiency in dendritic cells exacerbates acute kidney injury

scientific article published on 04 September 2018

Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial

scientific article published in September 2018

Roles of dendritic cells in murine hepatic warm and liver transplantation-induced cold ischemia/reperfusion injury.

scientific article

Second-set rejection of mouse liver allografts is dependent on radiation-sensitive nonparenchymal cells of graft bone marrow origin

scientific article published on 01 April 1996

Serum cyclosporin levels, hepatic drug metabolism and renal tubulotoxicity

scientific article published on 01 September 1984

Sphingosine 1-phosphate receptor agonism impairs skin dendritic cell migration and homing to secondary lymphoid tissue: association with prolonged allograft survival

scientific article published on 9 August 2008

Spontaneous and iatrogenically augmented leukocyte chimerism in organ transplant recipients

scientific article

State of immunosuppressive agents in organ transplantation ⬇️

scientific article published on December 1, 1992

Striking augmentation of hematopoietic cell chimerism in noncytoablated allogeneic bone marrow recipients by FLT3 ligand and tacrolimus

scientific article

Suppression of autoimmune thyroid disease by FK 506: influence on thyroid-infiltrating cells, adhesion molecule expression and anti-thyroglobulin antibody production ⬇️

scientific article published on 01 March 1993

Surface morphology of mononuclear phagocytes from normal and poly I. poly C-teated mice revealed using the surface replica technique

scientific article published on 01 October 1976

Systemic administration of CTLA4-Ig or anti-CD40 ligand antibody inhibits second-set rejection of mouse liver allografts

Systemic administration of anti-interleukin-10 antibody prolongs organ allograft survival in normal and presensitized recipients

scientific article published on 01 December 1998

Systemic administration of cellular interleukin-10 can exacerbate cardiac allograft rejection in mice

scientific article published on 01 December 1996

TGF-beta 1 pretreatment impairs the allostimulatory function of human bone marrow-derived antigen-presenting cells for both naive and primed T cells

scientific article

Taming the lions: manipulating dendritic cells for use as negative cellular vaccines in organ transplantation.

scientific article published on August 2008

The "other" mTOR complex: New insights into mTORC2 immunobiology and their implications

scientific article published on 19 March 2019

The Changing Immunology of Organ Transplantation ⬇️

scientific article published on October 15, 1995

The Fourth International Workshop on Clinical Transplant Tolerance

scientific article published on 12 June 2020

The Influence of Collagen, Fibronectin, and Laminin on the Maturation of Dendritic Cell Progenitors Propagated from Normal or Flt3-Ligand-Treated Mouse Liver ⬇️

scientific article published on 01 January 1997

The Influence of FK-506 and Low-Concentration Ciclosporin on Human Lymphocyte Activation Antigen Expression and Blastogenesis: a Flow Cytometric Analysis ⬇️

scientific article published on March 1, 1990

The Role of Cell Migration and Chimerism in Organ Transplant Acceptance and Tolerance Induction

scientific article

The STATus of PD-L1 (B7-H1) on tolerogenic APCs.

scientific article

The antilymphocytic activity of brequinar sodium and its potentiation by cytidine. Effects on lymphocyte proliferation and cytokine production

scientific article

The bidirectional paradigm of transplant immunology

scientific article

The biological basis of and strategies for clinical xenotransplantation

scientific article

The effect of rapamycin on renal function in the rat: a comparative study with cyclosporine ⬇️

scientific article published on 01 October 1991

The effects of rapamycin on humoral immunity in vivo. Suppression of primary responses but not of ongoing alloantibody synthesis or memory responses

scientific article published on December 1, 1992

The future of transplantation: with particular reference to chimerism and xenotransplantation

scientific article

The identity of proliferating donor-derived cells in tolerant mice

scientific article published on 01 June 1996

The influence of FK 506 on the thymus: implications of drug-induced injury to thymic epithelial cells

scientific article published on 01 February 1991

The influence of FK-506 on the thymus: an immunophenotypic and structural analysis ⬇️

scientific article published on 01 July 1990

The influence of enalapril or spironolactone on experimental cyclosporin nephrotoxicity

scientific article published on 01 March 1987

The lost chord: microchimerism and allograft survival

scientific article

The predictive value of enzymuria in cyclosporin A-induced renal toxicity in the rat

scientific article published on 01 July 1986

The secret behind non-antigen-pulsed autologous dendritic cell therapy in transplantation

scientific article published on 14 April 2014

The sphingosine-1-phosphate receptor agonist FTY720 modulates dendritic cell trafficking in vivo

scientific article

The two-way paradigm of transplantation immunology

scientific article

The use of MHC class I or class II "knock out" mice to investigate the role of these antigens in allosensitization.

scientific article published on February 1995

Thrombospondin-1 activation of signal-regulatory protein-α stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury

scientific article

Tolerogenic dendritic cell-regulatory T-cell interaction and the promotion of transplant tolerance

scientific article published on May 2009

Tolerogenic dendritic cells and the quest for transplant tolerance

scientific article published on 13 July 2007

Tolerogenic dendritic cells for autoimmune disease and transplantation

scientific article published on December 2008

Tolerogenic dendritic cells in organ transplantation

scientific article published on 29 October 2019

Tolerogenic plasmacytoid DC.

scientific article published on October 2010

Topical cyclosporin and immunologically-mediated skin disorders

scientific article published on 01 May 1987

Toxicity of rapamycin--a comparative and combination study with cyclosporine at immunotherapeutic dosage in the rat

scientific article published on 01 August 1991

Trafficking of APC from liver allografts of Flt3L-treated donors: augmentation of potent allostimulatory cells in recipient lymphoid tissue is associated with a switch from tolerance to rejection

scientific article published on 01 March 1999

Transduction of dendritic cell progenitors with a retroviral vector encoding viral interleukin-10 and enhanced green fluorescent protein allows purification of potentially tolerogenic antigen-presenting cells

scientific article published on 01 December 1999

Transduction of dendritic cells with adenoviral vectors encoding CTLA4-Ig markedly reduces their allostimulatory activity

Transgenic galectin-1 induces maturation of dendritic cells that elicit contrasting responses in naive and activated T cells

scientific article published in June 2006

Transplant Tolerance Induction: Insights From the Liver

scientific article published on 05 June 2020

Treatment of Cogan's syndrome with FK 506: a case report

scientific article

Treatment with CTLA4-Ig inhibits rejection of liver allografts from FIt3-ligand-treated donors

scientific article published on 01 February 1999

Treg-inducing microparticles promote donor-specific tolerance in experimental vascularized composite allotransplantation

scientific article published on 02 December 2019

Type-1 polarized nature of mouse liver CD8alpha- and CD8alpha+ dendritic cells: tissue-dependent differences offset CD8alpha-related dendritic cell heterogeneity

scientific article published in July 2003

Understanding, predicting and achieving liver transplant tolerance: from bench to bedside

scientific article published on 05 August 2020

Use of rapamycin in the induction of tolerogenic dendritic cells.

scientific article published on January 2009

Vascularized Composite Allotransplantation Research: The Emerging Field

scientific article published on 06 January 2012

Viral IL-10 gene transfer inhibits DTH responses to soluble antigens: evidence for involvement of genetically modified dendritic cells and macrophages

article

Xenobiotics, chimerism and the induction of tolerance following organ transplantation ⬇️

scientific article published on June 1, 1994

mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS.

scientific article

mTORC2 Deficiency Alters the Metabolic Profile of Conventional Dendritic Cells

scientific article published on 02 July 2019

mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.

scientific article published on 3 April 2015

mTORC2 deficiency in cutaneous dendritic cells potentiates CD8+ effector T cell responses and accelerates skin graft rejection

article

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