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List of works by Manoj Duraisingh

A DOC2 protein identified by mutational profiling is essential for apicomplexan parasite exocytosis

scientific article published in January 2012

A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion

scientific article (publication date: 13 August 2014)

A flow cytometry-based assay for measuring invasion of red blood cells by Plasmodium falciparum ⬇️

scientific article

A genetic screen for improved plasmid segregation reveals a role for Rep20 in the interaction of Plasmodium falciparum chromosomes

scientific article published in March 2002

A genome-wide map of diversity in Plasmodium falciparum

scientific article published on 10 December 2006

A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs

scientific article published on 20 June 2011

A novel erythrocyte binding antigen-175 paralogue from Plasmodium falciparum defines a new trypsin-resistant receptor on human erythrocytes

scientific article (publication date: 18 April 2003)

A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes

scientific article (publication date: 14 May 2010)

Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model

scientific article published on 16 February 2016

Aminoindoles, a novel scaffold with potent activity against Plasmodium falciparum

scientific article

Analysis of pfcrt, pfmdr1, dhfr, and dhps mutations and drug sensitivities in Plasmodium falciparum isolates from patients in Vietnam before and after treatment with artemisinin

scientific article published on March 2003

Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

scientific article

Antiparasitic chemotherapy: from genomes to mechanisms

scientific article

Antisense RNA and RNAi in protozoan parasites: working hard or hardly working?

scientific article published on 18 October 2007

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum ⬇️

scientific article

Bone Marrow Is a Major Parasite Reservoir in Plasmodium vivax Infection.

scientific article

CRISPR/Cas9 knockouts reveal genetic interaction between strain-transcendent erythrocyte determinants of Plasmodium falciparum invasion ⬇️

scientific article published on 19 October 2017

Characterization and structural studies of the Plasmodium falciparum ubiquitin and Nedd8 hydrolase UCHL3

scientific article

Contribution of the pfmdr1 gene to antimalarial drug-resistance

scientific article

Cooperativity between Plasmodium falciparum adhesive proteins for invasion into erythrocytes ⬇️

scientific article published on May 2009

Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression

scientific article

Distinct genomic architecture of Plasmodium falciparum populations from South Asia

scientific article published on 22 July 2016

Distribution of erythrocyte binding antigen 175 (EBA-175) alleles and ABO blood groups in a hypoendemic area in Senegal ⬇️

scientific article published on October 19, 2012

Editorial overview: Host-microbe interactions: parasites: sensing and responding to the changing environment: the life of protozoan parasites

scientific article published on 28 July 2014

Enhanced ex vivo Plasmodium vivax intraerythrocytic enrichment and maturation for rapid and sensitive parasite growth assays

scientific article published on 29 January 2018

Enrichment of reticulocytes from whole blood using aqueous multiphase systems of polymers

scientific article published on 18 October 2014

Epigenetic Regulation of Virulence Gene Expression in Parasitic Protozoa

scientific article

Epigenetic Variation and Regulation in Malaria Parasites

scholarly article by Manoj Duraisingh & Kristen M Skillman published 21 June 2018 in Annual Review of Microbiology

Epigenetic dysregulation of virulence gene expression in severe Plasmodium falciparum malaria

scientific article

Epigenetics in Plasmodium: what do we really know?

scientific article published on 18 June 2010

Erythrocyte invasion by Plasmodium falciparum: multiple ligand-receptor interactions and phenotypic switching.

scientific article published on January 2008

Erythrocyte-binding antigen 175 mediates invasion in Plasmodium falciparum utilizing sialic acid-dependent and -independent pathways ⬇️

scholarly article

Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite

scholarly article published 2018

Evidence for spleen dysfunction in malaria-HIV co-infection in a subset of pediatric patients

scientific article published on 26 February 2016

Evidence-based annotation of the malaria parasite's genome using comparative expression profiling

scientific article

Evolution of apicomplexan secretory organelles

scientific article published on 13 October 2012

Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans

scientific article published on January 2013

Extensive Shared Chemosensitivity between Malaria and Babesiosis Blood-Stage Parasites

scientific article

From Protease to Decarboxylase: THE MOLECULAR METAMORPHOSIS OF PHOSPHATIDYLSERINE DECARBOXYLASE.

scientific article published on 26 February 2015

Functional Analysis Reveals Geographical Variation in Inhibitory Immune Responses Against a Polymorphic Malaria Antigen

scientific article

Functional analysis of Plasmodium falciparum merozoite antigens: implications for erythrocyte invasion and vaccine development ⬇️

scientific article

Functional analysis of epigenetic regulation of tandem RhopH1/clag genes reveals a role in Plasmodium falciparum growth ⬇️

scientific article published on March 7, 2011

Functional analysis of erythrocyte determinants of Plasmodium infection ⬇️

scientific article published on April 19, 2012

Functional analysis of sirtuin genes in multiple Plasmodium falciparum strains

scientific article

Functional diversification between two related Plasmodium falciparum merozoite invasion ligands is determined by changes in the cytoplasmic domain ⬇️

scientific article published on February 2010

Gambian children successfully treated with chloroquine can harbor and transmit Plasmodium falciparum gametocytes carrying resistance genes.

scientific article

Genetic analysis of the cytoplasmic domain of the PfRh2b merozoite invasion protein of Plasmodium falciparum ⬇️

scientific article published on 19 September 2008

Genetic evidence for erythrocyte receptor glycophorin B expression levels defining a dominant Plasmodium falciparum invasion pathway into human erythrocytes ⬇️

scientific article

Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparum

scientific article published in April 2005

Heterochromatin-mediated control of virulence gene expression.

scientific article published on November 2006

Host Cell Tropism and Adaptation of Blood-Stage Malaria Parasites: Challenges for Malaria Elimination

scientific article published on 17 February 2017

Host-parasite interactions that guide red blood cell invasion by malaria parasites

scientific article published on May 2015

Human red blood cell-adapted Plasmodium knowlesi parasites: a new model system for malaria research

scientific article published on 12 March 2014

Identification and characterization of small molecule inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase

scientific article published on 8 October 2008

Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum

scientific article (publication date: 23 April 2009)

Identification and disruption of the gene encoding the third member of the low-molecular-mass rhoptry complex in Plasmodium falciparum

scientific article

Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors

scientific article

Identification by functional proteomics of a deubiquitinating/deNeddylating enzyme in Plasmodium falciparum

scientific article (publication date: September 2006)

Improved light microscopy counting method for accurately counting Plasmodium parasitemia and reticulocytemia

scientific article published on 13 April 2016

Improving malaria control in West Africa: interruption of transmission as a paradigm shift

scientific article published on 28 November 2011

In Vitro Genetic Analysis of an Erythrocyte Determinant of Malaria Infection ⬇️

scientific article published on October 19, 2010

Independent Origin and Global Distribution of Distinct Plasmodium vivax Duffy Binding Protein Gene Duplications

scientific article

Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria

scientific article published on 10 October 2016

Infection of laboratory colonies of Anopheles mosquitoes with Plasmodium vivax from cryopreserved clinical isolates

scientific article published on 22 July 2016

Inhibitory humoral responses to the Plasmodium falciparum vaccine candidate EBA-175 are independent of the erythrocyte invasion pathway ⬇️

scientific article published on 12 June 2013

Insights into an Optimization of Plasmodium vivax Sal-1 In Vitro Culture: The Aotus Primate Model

scientific article

Investigating the Pathogenesis of Severe Malaria: A Multidisciplinary and Cross-Geographical Approach

scientific article

Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum

scientific article published on 2 November 2017

Malaria evolution in South Asia: knowledge for control and elimination

scientific article published on 14 January 2012

Malaria in India: The Need for New Targets for Diagnosis and Detection of Plasmodium vivax

scientific article published on 29 November 2017

Malaria. A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion ⬇️

scientific article published on May 2015

Measuring Plasmodium falciparum Erythrocyte Invasion Phenotypes Using Flow Cytometry

scientific article published in January 2015

Molecular analysis of erythrocyte invasion in Plasmodium falciparum isolates from Senegal ⬇️

scientific article published on 30 April 2007

Molecular interactions governing host-specificity of blood stage malaria parasites

scientific article published on 30 October 2017

Molecular mechanism for switching of P. falciparum invasion pathways into human erythrocytes

scientific article

Multiple drug resistance genes in malaria -- from epistasis to epidemiology

scientific article

Negative selection of Plasmodium falciparum reveals targeted gene deletion by double crossover recombination

scientific article published in January 2002

Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model

scientific article

Nuclear repositioning precedes promoter accessibility and is linked to the switching frequency of a Plasmodium falciparum invasion gene ⬇️

scientific article

Optimization of flow cytometric detection and cell sorting of transgenic Plasmodium parasites using interchangeable optical filters ⬇️

scientific article published on September 5, 2012

PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum

scientific article

Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes ⬇️

scientific article (publication date: 3 March 2003)

Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony

scientific article (publication date: 17 February 2017)

Plasmodium falciparum Merozoite Surface Antigen, PfRH5, Elicits Detectable Levels of Invasion-Inhibiting Antibodies in Humans ⬇️

scientific article published on July 31, 2013

Plasmodium falciparum Sir2: an unusual sirtuin with dual histone deacetylase and ADP-ribosyltransferase activity

scientific article published on 7 September 2007

Plasmodium falciparum erythrocyte invasion through glycophorin C and selection for Gerbich negativity in human populations ⬇️

scientific article

Plasmodium falciparum transmission stages accumulate in the human bone marrow

scientific article

Plasmodium research in the postgenomic era.

scientific article

Population genetic analysis of large sequence polymorphisms in Plasmodium falciparum blood-stage antigens

scientific article

Population genomic structure and adaptation in the zoonotic malaria parasite Plasmodium knowlesi

scientific article

Resistance to antiparasitic drugs: the role of molecular diagnosis.

scientific article

Resistance to in sickle cell trait erythrocytes is driven by oxygen-dependent growth inhibition

article published in the Proceedings of the National Academy of Sciences of the United States of America

Reticulocyte Preference and Stage Development of Plasmodium vivax Isolates

scientific article published on 17 July 2016

Reticulocyte-binding protein homologue 1 is required for sialic acid-dependent invasion into human erythrocytes by Plasmodium falciparum

scientific article published in January 2005

Sahel, savana, riverine and urban malaria in West Africa: Similar control policies with different outcomes

scientific article published on 19 November 2011

Sickle Cell MicroRNAs Inhibit the Malaria Parasite ⬇️

scientific article published on August 16, 2012

Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum

scientific article (publication date: 14 April 2009)

Specific phosphorylation of the PfRh2b invasion ligand of Plasmodium falciparum ⬇️

scientific article published on June 15, 2013

Suggestive evidence for Darwinian Selection against asparagine-linked glycans of Plasmodium falciparum and Toxoplasma gondii

scientific article published on 25 September 2009

Targeting Plasmodium Proteases to Block Malaria Parasite Escape and Entry

scientific article published on 18 December 2017

The Clinically Tested Gardos Channel Inhibitor Senicapoc Exhibits Antimalarial Activity

scientific article

The Molecular Basis of Erythrocyte Invasion by Malaria Parasites

scientific article

The effect of Plasmodium falciparum Sir2a histone deacetylase on clonal and longitudinal variation in expression of the var family of virulence genes

scientific article published on 8 August 2009

To kill a piroplasm: genetic technologies to advance drug discovery and target identification in Babesia

scientific article published on 01 November 2018

Transcriptional control and gene silencing in Plasmodium falciparum

scientific article published on 10 July 2008

Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors

scientific article published on 24 November 2008

Unravelling a histone code for malaria virulence

scientific article

Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca2+ Signaling

scientific article

Variant merozoite protein expression is associated with erythrocyte invasion phenotypes in Plasmodium falciparum isolates from Tanzania

scientific article

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