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List of works by Harald Grallert

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Genetic studies of body mass index yield new insights for obesity biology

scientific article
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article
Discovery and refinement of loci associated with lipid levels

scientific article
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

scientific article
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article
Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)
Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article
Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study

scientific article
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article
New genetic loci link adipose and insulin biology to body fat distribution

scientific article
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article
DNA methylation and body-mass index: a genome-wide analysis

scientific article
Genome-wide association study identifies five loci associated with lung function

scientific article
The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)
Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article
Novel biomarkers for pre-diabetes identified by metabolomics

scientific article
Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants

scientific article
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

scientific article
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

scientific article published on 21 December 2016
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups

scientific journal article
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

scientific article published on 08 October 2018
The impact of low-frequency and rare variants on lipid levels

scientific article published on 11 May 2015
Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

scientific article
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

scientific article
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article
Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017
A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012
Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits

scientific article published on 06 September 2013
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

scientific article published on 18 November 2009
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

scientific article published on February 2016
Targeted metabolomics identifies reliable and stable metabolites in human serum and plasma samples

scientific article
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

scientific article published on 12 December 2016
DNA methylation of lipid-related genes affects blood lipid levels

scientific article published on 12 January 2015
Connecting genetic risk to disease end points through the human blood plasma proteome

scientific article published on 27 February 2017
Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms

scientific article published on January 2014
Cereulide synthetase gene cluster from emetic Bacillus cereus: structure and location on a mega virulence plasmid related to Bacillus anthracis toxin plasmid pXO1

scientific article
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018
Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms

scientific article
Childhood obesity is associated with changes in the serum metabolite profile

scientific article published on 4 October 2012
IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies

scientific article

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