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List of works by Ben Berkhout

A Combinatorial CRISPR-Cas9 Attack on HIV-1 DNA Extinguishes All Infectious Provirus in Infected T Cell Cultures

scientific article published on December 2016

A Plea for Justice for Jailed Medical Workers

scientific article published in Science

A Single H1 Promoter Can Drive Both Guide RNA and Endonuclease Expression in the CRISPR-Cas9 System

scientific article published on 01 November 2018

A chimeric HIV-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (GM-CSF) domain induces enhanced antibody and T cell responses

scientific article

A conditionally replicating HIV-based vector that stably expresses an antiviral shRNA against HIV-1 replication

scientific article published on 11 May 2006

A conditionally replicating SIV variant that can be used to study the mechanism of protection conferred by live attenuated SIV vaccines.

scientific article published on 3 October 2011

A conditionally replicating virus as a novel approach toward an HIV vaccine

scientific article published in January 2004

A highly virulent variant of HIV-1 circulating in the Netherlands

scientific article published on 4 February 2022

A human immunodeficiency virus type 1-infected individual with low viral load harbors a virus variant that exhibits an in vitro RNA dimerization defect

scientific article

A novel pancoronavirus RT-PCR assay: frequent detection of human coronavirus NL63 in children hospitalized with respiratory tract infections in Belgium

scientific article

A novel splice donor site in the gag-pol gene is required for HIV-1 RNA stability

scientific article published on 4 May 2006

A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses

scientific article published on 30 March 2016

A sensitive cell-based assay to measure the doxycycline concentration in biological samples.

scientific article

A short sequence motif in the 5' leader of the HIV-1 genome modulates extended RNA dimer formation and virus replication

scientific article

Adaptation of HIV-1 depends on the host-cell environment

scientific article published on 7 March 2007

Adenovirus types 5 and 35 seroprevalence in AIDS risk groups supports type 35 as a vaccine vector

scientific article published on May 2004

Aggressive HIV-1?

scientific article

Altered dynamics and differential infection profiles of lymphoid and myeloid cell subsets during acute and chronic HIV-1 infection

scientific article

Alternative tRNA priming of human immunodeficiency virus type 1 reverse transcription explains sequence variation in the primer-binding site that has been attributed to APOBEC3G activity

scientific article published on March 2005

An AUG codon upstream of rev and env open reading frames ensures optimal translation of the simian immunodeficiency virus Env protein ⬇️

scientific article published on December 20, 2012

Analysis of AgoshRNA maturation and loading into Ago2. ⬇️

scientific article published on 15 August 2017

Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness

scientific article

Antibacterial and antiviral effects of milk proteins and derivatives thereof

scientific article

Aspirin-like molecules that inhibit human immunodeficiency virus 1 replication

scientific article (publication date: May 2003)

Association between gp120 envelope V1V2 and V4V5 variable loop profiles in a defined HIV-1 transmission cluster

scientific article

Attachment factor and receptor engagement of SARS coronavirus and human coronavirus NL63.

scientific article published on January 2006

Attacking HIV-1 RNA versus DNA by sequence-specific approaches: RNAi versus CRISPR-Cas

scientific article published on October 2016

Autologous antibody capture to enrich immunogenic viruses for viral discovery

scientific article

Biological or pharmacological activation of protein kinase C alpha constrains hepatitis E virus replication

scientific article

Bone Marrow Gene Therapy for HIV/AIDS

scientific article

Boosting AgoshRNA activity by optimized 5'-terminal nucleotide selection

scientific article published on 16 April 2019

CD32+CD4+ T Cells Are Highly Enriched for HIV DNA and Can Support Transcriptional Latency

scientific article published on 01 February 2020

CRISPR therapy towards an HIV cure

scientific article published on 08 November 2019

CRISPR-Cas based antiviral strategies against HIV-1.

scientific article

CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape

scientific article published on 22 January 2016

CRISPR-Cas9 Dual-gRNA Attack Causes Mutation, Excision and Inversion of the HIV-1 Proviral DNA

scientific article published on 18 March 2020

Cell-associated HIV RNA: a dynamic biomarker of viral persistence

scientific article published on 15 April 2013

Cell-associated HIV-1 RNA predicts viral rebound and disease progression after discontinuation of temporary early ART

scientific article published on 26 March 2020

Cellular levels of HIV unspliced RNA from patients on combination antiretroviral therapy with undetectable plasma viremia predict the therapy outcome ⬇️

scientific article

Characterization of an HIV-1 group M variant that is distinct from the known subtypes

scientific article published on March 2007

Characterization of microRNAs derived from the HIV-1 TAR RNA hairpin.

scientific article published on 19 September 2013

Circularization of the HIV-1 RNA genome

scientific article (publication date: 2007)

Codon and amino acid usage in retroviral genomes is consistent with virus-specific nucleotide pressure

scientific article

Combinatorial CRISPR-Cas9 and RNA Interference Attack on HIV-1 DNA and RNA Can Lead to Cross-Resistance

scientific article published on 11 September 2017

Comparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein Trimers ⬇️

scientific article published on June 26, 2013

Comparison of single regulated lentiviral vectors with rtTA expression driven by an autoregulatory loop or a constitutive promoter

scientific article

Conditional live virus as a novel approach towards a safe live attenuated HIV vaccine

scientific article

Conditional virus replication as an approach to a safe live attenuated human immunodeficiency virus vaccine

scientific article

Conditionally replicating HIV and SIV variants

scientific article published on 14 May 2015

Conditionally-live attenuated SIV upregulates global T effector memory cell frequency under replication permissive conditions

scientific article published on 05 June 2013

Construction of Nef-positive doxycycline-dependent HIV-1 variants using bicistronic expression elements.

scientific article

Construction of a doxycycline-dependent simian immunodeficiency virus reveals a nontranscriptional function of tat in viral replication.

scientific article

Construction of doxycyline-dependent mini-HIV-1 variants for the development of a virotherapy against leukemias

scientific article

Control over HIV-1 replication by an antibiotic; a novel vaccination strategy with a drug-dependent virus

scientific article

Core structure of S2 from the human coronavirus NL63 spike glycoprotein

scientific article

Correction: Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe

scientific article published on 13 July 2017

Croup is associated with the novel coronavirus NL63

scientific article

Declining trend in transmission of drug-resistant HIV-1 in Amsterdam

scientific article published on July 2004

Deep Sequence Analysis of AgoshRNA Processing Reveals 3' A Addition and Trimming

scientific article published on 14 July 2015

Delineation of the Exact Transcription Termination Signal for Type 3 Polymerase III.

scientific article published on 21 November 2017

Dendritic cell-induced activation of latent HIV-1 provirus in actively proliferating primary T lymphocytes

scientific article

Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1.

scientific article

Dendritic cells potently purge latent HIV-1 beyond TCR-stimulation, activating the PI3K-Akt-mTOR pathway

article

Design and Evaluation of AgoshRNAs with 3'-Terminal HDV Ribozymes to Enhance the Silencing Activity

scientific article published on 01 January 2021

Design and Evaluation of Guide RNA Transcripts with a 3'-Terminal HDV Ribozyme to Enhance CRISPR-Based Gene Inactivation

scientific article published on 01 January 2021

Dicer-independent processing of small RNA duplexes: mechanistic insights and applications

scientific article published on 31 August 2017

Differences in HIV Type 1 RNA Plasma Load Profile of Closely Related Cocirculating Ethiopian Subtype C Strains: C and C′

article

Differential binding of tenofovir and adefovir to reverse transcriptase of hepatitis B virus

scientific article

Differential susceptibility of naïve, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission

scientific article

Dimerization and template switching in the 5' untranslated region between various subtypes of human immunodeficiency virus type 1.

scientific article

Disturbance of the microRNA pathway by commonly used lentiviral shRNA libraries limits the application for screening host factors involved in hepatitis C virus infection

scientific article

Diverse HIV-1 escape pathways from broadly neutralizing antibody PGDM1400 in humanized mice

scientific article published on 01 January 2020

ESF-EMBO symposium: antiviral applications of RNA interference

scientific article published on 18 September 2008

Easy and Accurate Reconstruction of Whole HIV Genomes from Short-Read Sequence Data

article

Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver.

scientific article published in January 2018

Efficient human immunodeficiency virus replication requires a fine-tuned level of transcription

scientific article published on March 2002

Efficient inhibition of HIV-1 expression by LNA modified antisense oligonucleotides and DNAzymes targeted to functionally selected binding sites

scientific article published on 26 April 2007

Emergence of a drug-dependent human immunodeficiency virus type 1 variant during therapy with the T20 fusion inhibitor.

scientific article

Engineered mini H1 promoters with dedicated RNA Polymerase II or III activity

scientific article published on 05 November 2020

Euclidean Distance Analysis Enables Nucleotide Skew Analysis in Viral Genomes

scientific article published on 30 October 2018

Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41

scientific article

Evolution rescues folding of human immunodeficiency virus-1 envelope glycoprotein GP120 lacking a conserved disulfide bond

scientific article

Extinction of all infectious HIV in cell culture by the CRISPR-Cas12a system with only a single crRNA

scientific article published on 13 April 2020

Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirology

scientific article

From clinical sample to complete genome: Comparing methods for the extraction of HIV-1 RNA for high-throughput deep sequencing

scientific article published on 4 August 2016

Functional analysis of the complex trans-activating response element RNA structure in simian immunodeficiency virus

scientific article published on 2 July 2008

Gene knockdown in malaria parasites via non-canonical RNAi

scientific article published on 01 January 2020

Gene therapy strategies to block HIV-1 replication by RNA interference

scientific article

Genome structure and transcriptional regulation of human coronavirus NL63

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HIV-1 RNAs: sense and antisense, large mRNAs and small siRNAs and miRNAs.

scientific article published on March 2015

HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome

scientific article

HIV-1 drug-resistance and drug-dependence

scientific article published on 25 October 2007

HIV-1 evolution: frustrating therapies, but disclosing molecular mechanisms

scientific article published on June 2010

HIV-1 reverse transcription: close encounters between the viral genome and a cellular tRNA.

scientific article published on January 2007

HIV-1 splicing is controlled by local RNA structure and binding of splicing regulatory proteins at the major 5' splice site

scientific article

HIV-1 tolerates changes in A-count in a small segment of the pol gene

scientific article published on 5 September 2017

HIV-1 transcriptional silencing caused by TRIM22 inhibition of Sp1 binding to the viral promoter

scientific article published on 18 December 2015

HIV-1N-Glycan Composition Governs a Balance between Dendritic Cell-Mediated Viral Transmission and Antigen Presentation ⬇️

scientific article published on September 28, 2011

Hairpin-induced tRNA-mediated (HITME) recombination in HIV-1.

scientific article published on 2 May 2006

Has the rate of CD4 cell count decline before initiation of antiretroviral therapy changed over the course of the Dutch HIV epidemic among MSM?

scientific article

High Current CD4+ T Cell Count Predicts Suboptimal Adherence to Antiretroviral Therapy

scientific article published on 15 October 2015

High prevalence of hepatitis B virus dual infection with genotypes A and G in HIV-1 infected men in Amsterdam, the Netherlands, during 2000-2011

scientific article

Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA.

scientific article published on 7 May 2008

Histatin 5-derived peptide with improved fungicidal properties enhances human immunodeficiency virus type 1 replication by promoting viral entry

scientific article

Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes

scientific article published on 28 December 2006

Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry

scientific article

Human coronavirus NL63, a new respiratory virus

scientific article published on September 2006

Human immunodeficiency virus type 1 escape is restricted when conserved genome sequences are targeted by RNA interference

scientific article

Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition

scientific article published on March 2004

Human immunodeficiency virus type 1 gp120 envelope characteristics associated with disease progression differ in family members infected with genetically similar viruses

scientific article published on 26 September 2012

Human immunodeficiency virus type 1 splicing at the major splice donor site is controlled by highly conserved RNA sequence and structural elements

scientific article published on 17 September 2015

Human immunodeficiency virus type 1 subtypes have a distinct long terminal repeat that determines the replication rate in a host-cell-specific manner

scientific article published on April 2004

IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation

scientific article published on 04 June 2019

Identification of alternative amino acid substitutions in drug-resistant variants of the HIV-1 reverse transcriptase

scientific article published on 01 July 2006

Identification of new human coronaviruses

scientific article published on April 2007

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes

scientific article

Improved single-chain transactivators of the Tet-On gene expression system

scientific article

Improvement of the CRISPR-Cpf1 system with ribozyme-processed crRNA

scientific article published on 29 November 2018

Improving miRNA Delivery by Optimizing miRNA Expression Cassettes in Diverse Virus Vectors

scientific article

Improving the safety of a conditional-live human immunodeficiency virus type 1 vaccine by controlling both gene expression and cell entry

scientific article published on March 2005

In vitro evidence that the untranslated leader of the HIV-1 genome is an RNA checkpoint that regulates multiple functions through conformational changes

scientific article

In vivo SELEX of single-stranded domains in the HIV-1 leader RNA.

scientific article

Increased multinucleoside drug resistance and decreased replicative capacity of a human immunodeficiency virus type 1 variant with an 8-amino-Acid insert in the reverse transcriptase

scientific article

Influence of a 3' Terminal Ribozyme on AgoshRNA Biogenesis and Activity

Influence of the loop size and nucleotide composition on AgoshRNA biogenesis and activity

scientific article published on June 2017

Inhibition of Virus Replication by RNA Interference

scientific article published on January 1, 2003

Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site

scientific article

Interaction of severe acute respiratory syndrome-coronavirus and NL63 coronavirus spike proteins with angiotensin converting enzyme-2.

scientific article

It's the virus, stupid--part 2

scientific article

Jan van der Noordaa (1934-2015); A Virologist Pur Sang

scientific article

Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan

scientific article

Lack of detection of XMRV in seminal plasma from HIV-1 infected men in The Netherlands

scientific article

Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction

scientific article

Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition

scientific article

Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes

scientific article

Major decline of hepatitis C virus incidence rate over two decades in a cohort of drug users

scientific article published on 03 March 2007

Mechanistic insights on the Dicer-independent AGO2-mediated processing of AgoshRNAs.

scientific article

Modest deviations from optimal adherence to antiretroviral therapy promote residual HIV-1 replication in the absence of virological rebound in plasma.

scientific article published on 3 October 2011

Modest nonadherence to antiretroviral therapy promotes residual HIV-1 replication in the absence of virological rebound in plasma

scientific article published on 20 August 2012

Modification of the Tet-On regulatory system prevents the conditional-live HIV-1 variant from losing doxycycline-control

scientific article published on 9 November 2006

Mutation of nucleotides around the +1 position of type 3 polymerase III promoters: The effect on transcriptional activity and start site usage

scientific article published on 9 June 2017

Novel AgoshRNA molecules for silencing of the CCR5 co-receptor for HIV-1 infection

scientific article

Novel replication-incompetent vector derived from adenovirus type 11 (Ad11) for vaccination and gene therapy: low seroprevalence and non-cross-reactivity with Ad5.

scientific article published on December 2004

Nucleotide composition of the Zika virus RNA genome and its codon usage

scientific article

Obituary: Axel Rethwilm (1959-2014)

scientific article

Obituary: Kuan-Teh Jeang

scientific article

Occult replication of a conditionally-live attenuated SIV profoundly upregulates T effector memory cell frequency.

scientific article published on 3 October 2011

On the biased nucleotide composition of the human coronavirus RNA genome

scientific article

On the nucleotide composition and structure of retroviral RNA genomes

scientific article

Only five of 10 strictly conserved disulfide bonds are essential for folding and eight for function of the HIV-1 envelope glycoprotein

scientific article published on 23 July 2008

Opening of the TAR hairpin in the HIV-1 genome causes aberrant RNA dimerization and packaging ⬇️

scientific article published on July 24, 2012

Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution

scientific article published on 5 June 2008

Possible applications for replicating HIV 1 vectors

scientific article published on May 2010

Potential mechanisms for cell-based gene therapy to treat HIV/AIDS.

scientific article

Probing alternative foldings of the HIV-1 leader RNA by antisense oligonucleotide scanning arrays

scientific article published on 3 February 2004

Probing the shRNA characteristics that hinder Dicer recognition and consequently allow Ago-mediated processing and AgoshRNA activity

scientific article published on 17 July 2014

Proceedings of the Frontiers of Retrovirology Conference 2016.

scientific article published on 26 September 2016

Protein X of hepatitis B virus: origin and structure similarity with the central domain of DNA glycosylase

scientific article published in 2011

Proteomic analysis of HIV-T cell interaction: an update

scientific article

RISCy business: MicroRNAs, pathogenesis, and viruses

scientific article published on 12 July 2007

RNA Polymerase II Activity of Type 3 Pol III Promoters.

scientific article

RNA detection and subtype C assessment of HIV-1 in infants with diarrhea in Ethiopia

scientific article published on 20 May 2009

RNA interference against viruses: strike and counterstrike

scientific article

RNA interference as an antiviral approach: targeting HIV-1.

scientific article published on April 2004

RNA structure modulates splicing efficiency at the human immunodeficiency virus type 1 major splice donor

scientific article

RNAi-Inducing Lentiviral Vectors for Anti-HIV-1 Gene Therapy ⬇️

scientific article published on January 1, 2011

Regulated HIV-2 RNA dimerization by means of alternative RNA conformations

scientific article

Replication kinetics and persistence of a conditionally live attenuated SIV (SIVrtTA) in vivo confers protection against SIVmac239 wild-type challenge in a rhesus macaque model

scientific article

Replication kinetics and persistence of a conditionally live attenuated SIV (SIVrtTA) in vivo confers protection against homologous and heterologous wild-type challenge in macaques

Retroviral microRNAs

scientific article published on 23 April 2014

Retroviral superinfection resistance

scientific article

Rise in seroprevalence of herpes simplex virus type 1 among highly sexual active homosexual men and an increasing association between herpes simplex virus type 2 and HIV over time (1984-2003).

scientific article

Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine

scientific article (publication date: December 2016)

SHAPE-directed Discovery of Potent shRNA Inhibitors of HIV-1 ⬇️

scientific article published on February 7, 2012

SIVdrl detection in captive mandrills: are mandrills infected with a third strain of simian immunodeficiency virus?

scientific article

Selecting the optimal Tet-On system for doxycycline-inducible gene expression in transiently transfected and stably transduced mammalian cells

scientific article published on 3 September 2015

Selection of T1249-resistant human immunodeficiency virus type 1 variants

scientific article published on 23 April 2008

Short Communication: Protective Efficacy of Broadly Neutralizing Antibody PGDM1400 Against HIV-1 Challenge in Humanized Mice

scientific article published on 22 August 2018

Sialoadhesin (CD169) expression in CD14+ cells is upregulated early after HIV-1 infection and increases during disease progression

scientific article published on 28 February 2007

Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.

scientific article

Stabilized HIV-1 Envelope Glycoprotein Trimers Lacking the V1V2 Domain, Obtained by Virus Evolution ⬇️

scientific article published on September 8, 2010

Steady increase in cellular HIV-1 load during the asymptomatic phase of untreated infection despite stable plasma viremia

scientific article published on 01 July 2010

Survey of the temporal changes in HIV-1 replicative fitness in the Amsterdam Cohort

scientific article published on 28 March 2007

Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies

scientific article

Tackling HIV Persistence: Pharmacological versus CRISPR-Based Shock Strategies

scientific article published on 29 March 2018

Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses

scientific article published on 28 December 2011

Tat has a dual role in simian immunodeficiency virus transcription ⬇️

scientific article published on July 18, 2012

Tat-dependent production of an HIV-1 TAR-encoded miRNA-like small RNA.

scientific article

Tet-On Systems For Doxycycline-inducible Gene Expression.

scientific article published on 24 May 2016

The A-nucleotide preference of HIV-1 in the context of its structured RNA genome

scientific article

The Ebola virus VP35 protein is a suppressor of RNA silencing

scientific article

The HIV RNA setpoint theory revisited

scientific article

The HIV-1 Tat Protein Has a Versatile Role in Activating Viral Transcription ⬇️

scientific article published on July 13, 2011

The HIV-1 Tat protein enhances splicing at the major splice donor site

scientific article

The Impact of HIV-1 Genetic Diversity on CRISPR-Cas9 Antiviral Activity and Viral Escape

article

The RNA structure of the major splice donor site controls HIV-1 splicing

The allosteric HIV-1 integrase inhibitor BI-D affects virion maturation but does not influence packaging of a functional RNA genome

scientific article

The antiviral activity of the milk protein lactoferrin against the human immunodeficiency virus type 1.

scientific article published in June 2004

The apical loop of the HIV-1 TAR RNA hairpin is stabilized by a cross-loop base pair

scientific article (publication date: 3 October 2003)

The biased nucleotide composition of the HIV genome: a constant factor in a highly variable virus ⬇️

scientific article published on November 6, 2012

The evolution of subtype B HIV-1 tat in the Netherlands during 1985-2012.

scientific article

The genetic stability of a conditional live HIV-1 variant can be improved by mutations in the Tet-On regulatory system that restrain evolution

scientific article published on 20 April 2006

The host environment drives HIV-1 fitness

scientific article

The impact of unprotected T cells in RNAi-based gene therapy for HIV-AIDS.

scientific article published on 12 December 2013

The influence of charge clustering on the anti-HIV-1 activity and in vivo distribution of negatively charged albumins.

scientific article

The influence of the 5΄-terminal nucleotide on AgoshRNA activity and biogenesis: importance of the polymerase III transcription initiation site

scientific article

The interplay between virus infection and the cellular RNA interference machinery

scientific article

The novel human coronaviruses NL63 and HKU1.

scientific article published on November 2006

The search for a T cell line for testing novel antiviral strategies against HIV-1 isolates of diverse receptor tropism and subtype origin

scientific article published on 31 March 2014

The tRNA primer activation signal in the human immunodeficiency virus type 1 genome is important for initiation and processive elongation of reverse transcription

scientific article

Titers of lentiviral vectors encoding shRNAs and miRNAs are reduced by different mechanisms that require distinct repair strategies

scientific article

Toward optimization of AgoshRNA molecules that use a non-canonical RNAi pathway: variations in the top and bottom base pairs

scientific article

Towards Antiviral shRNAs Based on the AgoshRNA Design

scientific article published on 18 June 2015

Towards an HIV cure: a global scientific strategy

scientific article

Trans-inhibition of HIV-1 by a long hairpin RNA expressed within the viral genome

scientific article published on March 2007

Translational HIV-1 research: from routine diagnostics to new virology insights in Amsterdam, the Netherlands during 1983-2013

scientific article published on 28 August 2013

Transmission of Risk-Group Specific HIV-1 Strains Among Dutch Drug Users for More Than 20 Years and Their Replacement by Nonspecific Strains After Switching to Low-Harm Drug Practices ⬇️

scientific article published on February 1, 2013

Triple HIV-1 infection

scientific article published on 01 June 2005

Unusual Cluster of HIV Type 1 Dual Infections in Groningen, The Netherlands

article

Upstream AUG Codons in the Simian Immunodeficiency Virus SIVmac239 Genome Regulate Rev and Env Protein Translation ⬇️

scientific article published on September 5, 2012

Viral evolution as a tool to improve the tetracycline-regulated gene expression system

scientific article published on 2 February 2004

Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe

scientific article

Viral load levels measured at set-point have risen over the last decade of the HIV epidemic in the Netherlands

scientific article

Virus evolution as a tool to study HIV-1 biology

scientific article published on January 2009

What do we measure when we measure cell-associated HIV RNA.

scientific article published on 29 January 2018

Widespread hepatitis B virus genotype G (HBV-G) infection during the early years of the HIV epidemic in the Netherlands among men who have sex with men

scientific article

With a Little Help from my Enteric Microbial Friends

scientific article

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