List of works - Ida Surakka

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

scientific article (publication date: 11 August 2012)

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

scientific article

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

scientific article published on 21 June 2013

Genome-wide association study identifies five loci associated with lung function

scientific article

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

scientific article

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

scientific article

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

scientific article published on 23 September 2010

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Childhood adversities are associated with shorter telomere length at adult age both in individuals with an anxiety disorder and controls

scientific article

The impact of low-frequency and rare variants on lipid levels

scientific article published on 11 May 2015

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

scientific article

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

scientific journal article

Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15.

scientific article published on 23 July 2009

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function

scientific article

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

scientific article published on 6 February 2017

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

scientific article

Genome-wide association analysis identifies six new loci associated with forced vital capacity

scientific article

Distinct variants at LIN28B influence growth in height from birth to adulthood

scientific article

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

scientific article published on 30 July 2018

Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes

scientific article

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

scientific article

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

scientific article

Telomere length in circulating leukocytes is associated with lung function and disease

scientific article published on 5 December 2013

Founder population-specific HapMap panel increases power in GWA studies through improved imputation accuracy and CNV tagging

scientific article

Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects

scientific article

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

scientific article published in Nature Communications

Genomic, Transcriptomic, and Lipidomic Profiling Highlights the Role of Inflammation in Individuals With Low High-density Lipoprotein Cholesterol

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

scientific article

A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample

scientific article

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 25 February 2019

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

scientific article

Genetic evidence of assortative mating in humans

scholarly article

Partial sleep restriction activates immune response-related gene expression pathways: experimental and epidemiological studies in humans

scientific article

OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism

scientific article

The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits

scientific article

European lactase persistence genotype shows evidence of association with increase in body mass index

scientific article

Trends in Door-to-Thrombolysis Time in the Safe Implementation of Stroke Thrombolysis Registry: Effect of Center Volume and Duration of Registry Membership.

scientific article published on 31 March 2015

A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol

scientific article

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

scientific article published on 27 December 2017

Mondo-Mlx Mediates Organismal Sugar Sensing through the Gli-Similar Transcription Factor Sugarbabe.

scientific article published on 30 September 2015

List of works by Ida Surakka

Biological, clinical and population relevance of 95 loci for blood lipids

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Discovery and refinement of loci associated with lipid levels

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

Identification of seven loci affecting mean telomere length and their association with disease

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

Genome-wide association study identifies five loci associated with lung function

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

Common variants associated with plasma triglycerides and risk for coronary artery disease

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

Childhood adversities are associated with shorter telomere length at adult age both in individuals with an anxiety disorder and controls

The impact of low-frequency and rare variants on lipid levels

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15.

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

Genome-wide association analysis identifies six new loci associated with forced vital capacity

Distinct variants at LIN28B influence growth in height from birth to adulthood

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

Telomere length in circulating leukocytes is associated with lung function and disease

Founder population-specific HapMap panel increases power in GWA studies through improved imputation accuracy and CNV tagging

Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

Genomic, Transcriptomic, and Lipidomic Profiling Highlights the Role of Inflammation in Individuals With Low High-density Lipoprotein Cholesterol

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

Genetic evidence of assortative mating in humans

Partial sleep restriction activates immune response-related gene expression pathways: experimental and epidemiological studies in humans

OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism

The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits

European lactase persistence genotype shows evidence of association with increase in body mass index

Trends in Door-to-Thrombolysis Time in the Safe Implementation of Stroke Thrombolysis Registry: Effect of Center Volume and Duration of Registry Membership.

A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

Mondo-Mlx Mediates Organismal Sugar Sensing through the Gli-Similar Transcription Factor Sugarbabe.