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List of works by Harm-Jan Westra

52 Genetic Loci Influencing Myocardial Mass

scientific article

A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis

scientific article

A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention

scientific article published on 30 August 2011

A genome-wide association study of circulating galectin-3

scientific article

An integrative systems genetics approach reveals potential causal genes and pathways related to obesity

scientific article

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

scientific article

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

scientific article published on 20 July 2015

Biological interpretation of genome-wide association studies using predicted gene functions

scientific article published on 19 January 2015

Blood pressure loci identified with a gene-centric array

scientific article

Cell Specific eQTL Analysis without Sorting Cells

scientific article published on 8 May 2015

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

scientific article

Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer

scientific article

DeepSAGE reveals genetic variants associated with alternative polyadenylation and expression of coding and non-coding transcripts

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Discovery and fine mapping of serum protein loci through transethnic meta-analysis

scientific article

Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant

scientific article

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

scientific article published on 21 June 2013

Gene expression analysis identifies global gene dosage sensitivity in cancer.

scientific article published on 12 January 2015

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on 18 April 2016

Genetics of rheumatoid arthritis contributes to biology and drug discovery

scientific article

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels

scientific article

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

scientific article published on 16 October 2020

Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration

scientific article published on 11 December 2014

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

scientific article

Human disease-associated genetic variation impacts large intergenic non-coding RNA expression

scientific article

Identification of context-dependent expression quantitative trait loci in whole blood

scientific article published on 5 December 2016

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response

scientific article published on 06 April 2020

Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians

scientific article

Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids

scientific article published on 01 October 2020

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

scientific journal article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

scientific article

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

scientific article published in Nature Communications

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells

scientific article

RETRACTED ARTICLE: Detection and replication of epistasis influencing transcription in humans

retracted scholarly article

SMIM1 underlies the Vel blood group and influences red blood cell traits

scientific article

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The impact of low-frequency and rare variants on lipid levels

scientific article published on 11 May 2015

The transcriptional landscape of age in human peripheral blood

scientific article

Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

scientific article

Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression

scientific article

reGenotyper: Detecting mislabeled samples in genetic data

scientific article (publication date: 2017)

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