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List of works by Terho Lehtimäki

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article

5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.

scientific article published in August 2009

52 Genetic Loci Influencing Myocardial Mass

scientific article

A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism

scientific article published on 25 September 2015

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A Longitudinal Multilevel Study of the "Social" Genotype and Diversity of the Phenotype

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

scientific article published on 24 March 2017

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A combination of three common inherited mitochondrial DNA polymorphisms promotes longevity in Finnish and Japanese subjects

scientific article published on 01 February 2005

A comparison of the accuracy of Illumina HumanHT-12 v3 Expression BeadChip and TaqMan qRT-PCR gene expression results in patient samples from the Tampere Vascular Study.

scientific article

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

A diagnosis of the metabolic syndrome in youth that resolves by adult life is associated with a normalization of high carotid intima-media thickness and type 2 diabetes mellitus risk: the Bogalusa heart and cardiovascular risk in young Finns studies

scientific article published on 26 September 2012

A disintegrin and metalloprotease -8 and -15 and susceptibility for ascending aortic dissection.

scientific article

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

scientific article published on 18 June 2015

A genome-wide association meta-analysis identifies new childhood obesity loci

scientific article

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation

scientific article

A genome-wide association meta-analysis on apolipoprotein A-IV concentrations

scientific article published on 12 July 2016

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms

scientific article published on 16 May 2017

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study

scientific article

A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure

scientific article published on 27 March 2015

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

scientific article

A longitudinal analysis on associations of adiponectin levels with metabolic syndrome and carotid artery intima-media thickness. The Cardiovascular Risk in Young Finns Study

scientific article

A meta-analysis of genome-wide association studies identifies multiple longevity genes

scientific article published on 14 August 2019

A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern

scientific article

A metabolic view on menopause and ageing

scientific article published on 21 August 2014

A moderate dose of red wine, but not de-alcoholized red wine increases coronary flow reserve

scientific article published on 26 July 2007

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

scientific article

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A randomized trial of early detection of clinically significant prostate cancer (ProScreen): study design and rationale

scientific article

A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle

scientific article

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

scientific article published on 01 October 2019

ACE polymorphism and response to electroconvulsive therapy in major depression

scientific article published on 4 May 2009

ADAM-9, ADAM-15, and ADAM-17 are upregulated in macrophages in advanced human atherosclerotic plaques in aorta and carotid and femoral arteries--Tampere vascular study

scientific article published in January 2009

ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study

scientific article published in January 2009

Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis

scientific article published on 01 November 2019

Abnormal splicing of NEDD4 in myotonic dystrophy type 2: possible link to statin adverse reactions

scientific article

Absence of association between an intercellular adhesion molecule 1 gene E469K polymorphism and Alzheimer's disease in Finnish patients

scientific article published in January 2003

Activated immune-inflammatory pathways are associated with long-standing depressive symptoms: Evidence from gene-set enrichment analyses in the Young Finns Study

scientific article

Activation of indoleamine 2,3-dioxygenase-induced tryptophan degradation in advanced atherosclerotic plaques: Tampere vascular study

scientific article published in January 2010

Adhesion Molecules in Multiple Sclerosis

scientific article (publication date: April 2000)

Adhesion molecules in multiple sclerosis: relation to subtypes of disease and methylprednisolone therapy

scientific article (publication date: April 2000)

Adolescence Risk Factors Are Predictive of Coronary Artery Calcification at Middle Age

scholarly article by Olli Hartiala et al published October 2012 in Journal of the American College of Cardiology

Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: the Cardiovascular Risk in Young Finns Study

scientific article

Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health

scientific article published on 28 April 2021

Adverse childhood environment and self-reported sleep in adulthood: The Young Finns Study

scientific article published on 20 June 2019

Age and gender biases in secondary prevention of coronary heart disease in a Finnish university hospital setting

scientific article (publication date: 2007)

Age-dependent association between hepatic lipase gene C-480T polymorphism and the risk of pre-hospital sudden cardiac death: the Helsinki Sudden Death Study

scientific article

Age-dependent association of gut bacteria with coronary atherosclerosis: Tampere Sudden Death Study

scientific article published on 22 August 2019

Age-dependent interaction of apolipoprotein E gene with eastern birthplace in Finland affects severity of coronary atherosclerosis and risk of fatal myocardial infarction--Helsinki Sudden Death Study

scientific article published on 30 October 2012

Allelic variant of NOS1AP effects on cardiac alternans of repolarization during exercise testing

scientific article

Amerindian-specific regions under positive selection harbour new lipid variants in Latinos

scientific article

An interaction map of circulating metabolites, immune gene networks, and their genetic regulation

scientific article

Analysis of apoptosis-related genes in patients with clinically isolated syndrome and their association with conversion to multiple sclerosis

article

Analysis of free, mono- and diacetylated polyamines from human urine by LC-MS/MS.

scientific article published on 15 October 2013

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Antibody titer against malondialdehyde-modified LDL compares with HDL cholesterol concentration in identifying angiographically verified coronary artery disease. Comparison of tests by ROC analysis

scientific article published in January 2005

Aortic sinus diameter in middle age is associated with body size in young adulthood

scientific article published in November 2017

Apolipoprotein A-I concentrations and risk of coronary artery disease: A Mendelian randomization study

scientific article published on 14 February 2020

Apolipoprotein A-I/C-III/A-IV SstI and Apolipoprotein B XbaI Polymorphisms Do not Affect Early Functional and Structural Changes in Atherosclerosis

scientific article published on 01 May 2007

Apolipoprotein A-I/C-III/A-IV SstI and apolipoprotein B XbaI polymorphisms and their association with carotid artery intima-media thickness in the Finnish population. The Cardiovascular Risk in Young Finns Study

scientific article published in January 2005

Apolipoprotein B is related to arterial pulse wave velocity in young adults: The Cardiovascular Risk in Young Finns Study

scholarly article by Teemu Koivistoinen et al published January 2011 in Atherosclerosis

Apolipoprotein B, oxidized low-density lipoprotein, and LDL particle size in predicting the incidence of metabolic syndrome: the Cardiovascular Risk in Young Finns study

scientific article published on 29 September 2011

Apolipoprotein E gene polymorphism, hypercholesterolemia and glomerular filtration rate in type 2 diabetic subjects: a 9-year follow-up study.

scientific article

Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nonagenarians

scientific article published in March 2006

Apolipoprotein E polymorphism is associated with age of onset in schizophrenia

scientific article published on 18 June 2004

Apoptosis-related molecules in blood in multiple sclerosis

scientific article

Arterial pulse wave velocity in relation to carotid intima-media thickness, brachial flow-mediated dilation and carotid artery distensibility: The Cardiovascular Risk in Young Finns Study and the Health 2000 Survey

article

Arterial tension time reflects subclinical atherosclerosis, arterial stiffness and stroke volume

scientific article published on 28 July 2011

Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression

scientific article

Association analyses based on false discovery rate implicate new loci for coronary artery disease ⬇️

scientific article published on 17 July 2017

Association analysis of allelic variants of USF1 in coronary atherosclerosis

scientific article published on 14 February 2008

Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach

scientific article

Association between the C957T polymorphism of the dopamine D2 receptor gene and schizophrenia

scientific article published on 14 September 2006

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

scientific article published on 04 September 2019

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

scientific article published on 21 March 2019

Association of EGF polymorphism with schizophrenia in Finnish men.

scientific article published in May 2004

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

scientific article published on 13 July 2020

Association of Known Loci With Lipid Levels Among Children and Prediction of Dyslipidemia in Adults

Association of Neuropeptide Y Polymorphism With the Occurrence of Type 1 and Type 2 Alcoholism ⬇️

scientific article published on October 1, 2001

Association of apolipoprotein E promoter polymorphisms with bone structural traits is modified by dietary saturated fat intake — The Cardiovascular Risk in Young Finns Study

scholarly article by Sanna Tolonen et al published May 2011 in Bone

Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts

scientific article published on 28 February 2018

Association of circulating metabolites with healthy diet and risk of cardiovascular disease: analysis of two cohort studies.

scientific article

Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals

scientific article published on 01 August 2019

Association of high sensitive C-reactive protein with apolipoprotein E polymorphism in children and young adults: the Cardiovascular Risk in Young Finns Study

scientific article published in January 2008

Association of lifetime blood pressure with adulthood exercise blood pressure response: the cardiovascular risk in young Finns study

scientific article published on 05 January 2021

Association of mannan-binding lectin deficiency with venous bypass graft occlusions in patients with coronary heart disease

scientific article published in January 2002

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

Association of neuroimmune guidance cue netrin-1 and its chemorepulsive receptor UNC5B with atherosclerotic plaque expression signatures and stability in human(s): Tampere Vascular Study (TVS).

scientific article

Association of paraoxonase-1 M55L genotype and alcohol consumption with coronary atherosclerosis: the Helsinki Sudden Death Study

scientific article

Association of physical activity in childhood and early adulthood with carotid artery elasticity 21 years later: the cardiovascular risk in Young Finns Study

scientific article

Association of resting heart rate with cardiovascular function: a cross-sectional study in 522 Finnish subjects

scientific article

Association of serum MMP-9 with autoantibodies against oxidized LDL ⬇️

scientific article published on January 1, 2002

Association of the IL6-174(G/C) polymorphism with C-reactive protein concentration after weight loss in obese men.

scientific article published on June 2006

Association of the apolipoprotein E gene, its promoter polymorphisms and haplotypes with depressive symptoms. The Cardiovascular Risk in Young Finns Study

scientific article

Association of the novel single-nucleotide polymorphism which increases oxidized low-density lipoprotein levels with cerebrovascular disease events

Association of thyrotropin with arterial pulse wave velocity in young adults: the Cardiovascular Risk in Young Finns Study

scientific article published on 4 September 2014

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

scientific article

Associations between serum uric acid and markers of subclinical atherosclerosis in young adults. The cardiovascular risk in Young Finns study

scholarly article by Mervi Oikonen et al published August 2012 in Atherosclerosis

Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke

scientific article published on 17 March 2016

Asymmetric dimethylarginine (ADMA) has a role in regulating systemic vascular tone in young healthy subjects: the cardiovascular risk in young Finns study

scientific article published on 12 June 2008

Asymmetric dimethylarginine and hemodynamic regulation in middle-aged men

Asymmetrical dimethylarginine (ADMA) and risk of acute coronary events. Does statin treatment influence plasma ADMA levels?

scientific article

Atrioventricular conduction and cardiovascular mortality: Assessment of recovery PR interval is superior to pre-exercise measurement

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 01 June 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 01 May 2019

Autoimmunity and atherosclerosis: the presence of antinuclear antibodies is associated with decreased carotid elasticity in young women. The Cardiovascular Risk in Young Finns Study

scientific article published on 24 September 2009

BDNF and NRG1 polymorphisms and temperament in selective serotonin reuptake inhibitor-treated patients with major depression

scientific article

BDNF polymorphism rs11030101 is associated with the efficacy of electroconvulsive therapy in treatment-resistant depression

scientific article

BMI Trajectories Associated With Resolution of Elevated Youth BMI and Incident Adult Obesity

scientific article published on 19 December 2017

Bacterial DNA findings in ruptured and unruptured intracranial aneurysms

scientific article published on 18 January 2016

Bacterial DNA signatures in carotid atherosclerosis represent both commensals and pathogens of skin origin

scientific article published on January 2013

Bacterial signatures in thrombus aspirates of patients with lower limb arterial and venous thrombosis

scientific article published on 25 August 2017

Bacterial signatures in thrombus aspirates of patients with myocardial infarction

scientific article

Bayesian hierarchical piecewise regression models: a tool to detect trajectory divergence between groups in long-term observational studies

scientific article

Beyond LDL-C lowering: distinct molecular sphingolipids are good indicators of proprotein convertase subtilisin/kexin type 9 (PCSK9) deficiency

scientific article published on 6 April 2013

Bidirectional pathways between psychosocial risk factors and paranoid ideation in a general nonclinical population

scientific article published on 21 October 2020

Biomarker Glycoprotein Acetyls Is Associated With the Risk of a Wide Spectrum of Incident Diseases and Stratifies Mortality Risk in Angiography Patients

scientific article published on 01 November 2018

Birth weight and adult income: An examination of mediation through adult height and body mass

article by Jaakko Pehkonen et al published 11 July 2021 in Health Economics

Birth weight, adult weight, and cardiovascular biomarkers: Evidence from the Cardiovascular Young Finns Study

scientific article

Blood hsa-miR-122-5p and hsa-miR-885-5p levels associate with fatty liver and related lipoprotein metabolism-The Young Finns Study

scientific article published on 05 December 2016

Blood leukocyte count is a risk factor for intima-media thickening and subclinical carotid atherosclerosis in middle-aged men.

scientific article published on 27 December 2005

Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study

scientific article

Blood pathway analyses reveal differences between prediabetic subjects with or without dyslipidaemia. The Cardiovascular Risk in Young Finns Study

scientific article published on 13 June 2017

Both youth and long-term vitamin D status is associated with risk of type 2 diabetes mellitus in adulthood: a cohort study

scientific article published on 7 November 2017

Brain-derived neurotrophic factor (BDNF) polymorphisms G196A and C270T are not associated with response to electroconvulsive therapy in major depressive disorder

scientific article published in February 2007

Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults

scientific article published on 5 November 2012

C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis

scientific article published on 11 January 2022

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

scientific article published on 29 September 2017

CVD risk factors and surrogate markers - Urban-rural differences

scientific article published on 29 August 2019

CYP1A2 polymorphism -1545C > T (rs2470890) is associated with increased side effects to clozapine

scientific article

Carbonic anhydrases II and XII are up-regulated in osteoclast-like cells in advanced human atherosclerotic plaques-Tampere Vascular Study

scientific article published in July 2010

Cardiometabolic Health Among Adult Offspring of Hypertensive Pregnancies: The Cardiovascular Risk in Young Finns Study

scientific article published on 6 January 2018

Cardiometabolic and Inflammatory Biomarkers as Mediators Between Educational Attainment and Functioning at the Age of 90 Years

scientific article published on 31 August 2015

Cardiorespiratory Fitness and Risk of Fatty Liver: The Young Finns Study

scientific article published on 11 April 2017

Cardiorespiratory fitness and heart rate recovery predict sudden cardiac death independent of ejection fraction

scientific article published on 17 August 2019

Cardiovascular Health Trajectories From Childhood Through Middle Age and Their Association With Subclinical Atherosclerosis

scientific article published on 11 March 2020

Cardiovascular Risk Factors From Childhood and Midlife Cognitive Performance: The Young Finns Study

scientific article published in May 2017

Cardiovascular risk factors in 2011 and secular trends since 2007: the Cardiovascular Risk in Young Finns Study

scientific article published on 22 July 2014

Cardiovascular risk scores in the prediction of subclinical atherosclerosis in young adults: evidence from the cardiovascular risk in a young Finns study

scientific article

Carotid artery intima-media thickness in children with type 1 diabetes

scientific article published in February 2002

Carotid atherosclerosis in chronic renal failure-the central role of increased plaque burden

scientific article published on 01 December 2003

Catechol-O-methyltransferase (COMT) polymorphisms predict treatment response in electroconvulsive therapy

scientific article published on 14 August 2007

Catechol-O-methyltransferase and monoamine oxidase A genotypes and drug response to conventional neuroleptics in schizophrenia

scientific article published in October 2003

Catechol-O-methyltransferase val108/158met genotype and response to antipsychotic medication in schizophrenia

scientific article published on 01 June 2007

Catechol-O-methyltransferase val108/158met genotype, major depressive disorder and response to selective serotonin reuptake inhibitors in major depressive disorder

scientific article published on 13 January 2010

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

scientific article (publication date: 2013)

Characterization of systemic metabolic phenotypes associated with subclinical atherosclerosis

Childbearing, child-rearing, cardiovascular risk factors, and progression of carotid intima-media thickness: the Cardiovascular Risk in Young Finns study

scientific article published on 10 June 2010

Childhood Exposure to Passive Smoking and Bone Health in Adulthood: The Cardiovascular Risk in Young Finns Study

scientific article published on 01 June 2019

Childhood Infections, Socioeconomic Status, and Adult Cardiometabolic Risk

scientific article published on 27 May 2016

Childhood Serum Fatty Acid Quality Is Associated with Adult Carotid Artery Intima Media Thickness in Women but Not in Men

Childhood Socioeconomic Disadvantage and Risk of Fatty Liver in Adulthood: The Cardiovascular Risk in Young Finns Study

scientific article published on 20 December 2019

Childhood Socioeconomic Status and Arterial Stiffness in Adulthood: The Cardiovascular Risk in Young Finns Study

scientific article published on 14 August 2017

Childhood adiposity, adult adiposity, and the ACE gene insertion/deletion polymorphism: evidence of gene-environment interaction effects on adult blood pressure and hypertension status in adulthood

scientific article published in November 2018

Childhood and long-term dietary calcium intake and adult cardiovascular risk in a population with high calcium intake

scientific article published on 18 September 2020

Childhood environmental and genetic predictors of adulthood obesity: the cardiovascular risk in young Finns study

scientific article

Childhood exposure to parental smoking and life-course overweight and central obesity

scientific article published on 11 December 2020

Childhood nutrition in predicting metabolic syndrome in adults: the cardiovascular risk in Young Finns Study

scientific article

Childhood physical, environmental, and genetic predictors of adult hypertension: the cardiovascular risk in young Finns study

scientific article

Childhood predictors of adult fatty liver. The Cardiovascular Risk in Young Finns Study

scientific article published on 24 May 2016

Childhood risk factors and carotid atherosclerotic plaque in adulthood: The Cardiovascular Risk in Young Finns Study

scientific article published on 30 November 2019

Childhood serum cholesterol ester fatty acids are associated with blood pressure 27 y later in the Cardiovascular Risk in Young Finns Study

scientific article published on 9 May 2012

Cholesterol absorption and synthesis in pediatric kidney, liver, and heart transplant recipients

scientific article published in February 2006

Cholesterol-lowering properties and safety of chitosan

scientific article

Chromosome X-wide association study identifies Loci for fasting insulin and height and evidence for incomplete dosage compensation

scientific article

Circulating cell-free DNA in health and disease — the relationship to health behaviours, ageing phenotypes and metabolomics

scientific article published in 2022

Circulating cell-free DNA is associated with cardiometabolic risk factors: The Health 2000 Survey

article

Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: the Vitality 90+ Study

scientific article published on 03 March 2012

Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations

scientific article published in Scientific Reports

Circulating metabolite predictors of glycemia in middle-aged men and women

scientific article

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

scientific article published on 04 October 2019

Circulating microRNAs as biomarkers in progressive multiple sclerosis

scientific article

Circulating oxidized low-density lipoprotein and common carotid artery intima-media thickness in a random sample of middle-aged men.

scientific article published in May 2004

Cognitive performance in young adulthood and midlife: Relations with age, sex, and education-The Cardiovascular Risk in Young Finns Study

scientific article published on 2 November 2015

Cohort Profile: The Cardiovascular Risk in Young Finns Study

scientific article published on 08 February 2008

Combination of low blood pressure response, low exercise capacity and slow heart rate recovery during an exercise test significantly increases mortality risk

scientific article published on 07 November 2019

Combined assessment of heart rate recovery and T-wave alternans during routine exercise testing improves prediction of total and cardiovascular mortality: the Finnish Cardiovascular Study.

scientific article published on 14 August 2009

Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation

scientific article published on 01 February 2019

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

article by Padhraig Gormley et al published 16 May 2018 in Neuron

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

article by Padhraig Gormley et al published September 2018 in Neuron

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common polymorphism in the oxytocin receptor gene (OXTR) is associated with human social recognition skills

scientific article published on 23 December 2013

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Common variation in NOS1AP and KCNH2 genes and QT interval duration in young adults. The Cardiovascular Risk in Young Finns Study

scientific article

Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest

scientific article published on 10 January 2014

Common variation in the ADAM8 gene affects serum sADAM8 concentrations and the risk of myocardial infarction in two independent cohorts

scientific article

Complement factor H 402His variant confers an increased mortality risk in Finnish nonagenarians: the Vitality 90+ study

scientific article published on 26 October 2008

Complementary prediction of cardiovascular events by estimated apo- and lipoprotein concentrations in the working age population. The Health 2000 Study

scientific article published on 24 April 2012

Computationally estimated apolipoproteins B and A1 in predicting cardiovascular risk

scientific article published on 2 November 2012

Consortium genome-wide meta-analysis for childhood dental caries traits

Consortium-based genome-wide meta-analysis for childhood dental caries traits

scholarly article by Simon Haworth published in September 2018

Conventional and Mendelian randomization analyses suggest no association between lipoprotein(a) and early atherosclerosis: the Young Finns Study

scientific article

Conventional cardiovascular risk factors and metabolic syndrome in predicting carotid intima-media thickness progression in young adults: the cardiovascular risk in young Finns study.

scientific article

Coronary Artery Disease-Associated Locus on Chromosome 9p21 and Early Markers of Atherosclerosis

scientific article published on 03 July 2008

Coronary artery calcification is related to functional polymorphism of matrix metalloproteinase 3: the Helsinki Sudden Death Study

scientific article published on 01 October 2002

Coronary artery wall atherosclerosis in relation to the estrogen receptor 1 gene polymorphism: an autopsy study

scientific article published on 17 January 2002

Coronary heart disease risk factor levels in eastern and western Finland from 1980 to 2011 in the cardiovascular risk in Young Finns study

scientific article published on 15 November 2018

Coronary heart disease risk factors, coronary artery calcification and epicardial fat volume in the Young Finns Study

scientific article published on 20 April 2015

Coronary reactivity, homocysteine and methylenetetrahydrofolate reductase gene variation in young men during pravastatin therapy

scientific article published on 13 May 2007

Correction: Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA

scientific article published in PLoS ONE

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition

scientific article published on 06 March 2020

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

scientific article published on 21 October 2019

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article published on 26 May 2017

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on November 2016

Cross-sectional associations between physical activity and selected coronary heart disease risk factors in young adults. The Cardiovascular Risk in Young Finns Study

scientific article published in July 2011

DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

scientific article published on 07 January 2021

DRD2 C32806T modifies the effect of child-rearing environment on adulthood novelty seeking

scientific article published in April 2009

Decreased endothelin-1 levels after acute consumption of red wine and de-alcoholized red wine

scientific article published on 25 January 2010

Deficiency in Melanocortin 1 Receptor Signaling Predisposes to Vascular Endothelial Dysfunction and Increased Arterial Stiffness in Mice and Humans

scientific article published on 30 April 2015

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders

scientific article published on 04 August 2013

Delta-6-desaturase gene polymorphism is associated with lipoprotein oxidation in vitro

scientific article published on 30 May 2013

Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci

scientific article

Detection of smell print differences between nonmalignant and malignant prostate cells with an electronic nose

scientific article

Determinants of arterial nitrate-mediated dilatation in children: role of oxidized low-density lipoprotein, endothelial function, and carotid intima-media thickness

scientific article

Determinants of bone strength and fracture incidence in adult Finns: Cardiovascular Risk in Young Finns Study (the GENDI pQCT study)

article published in 2010

Determinants of exercise peak arterial blood pressure, circulatory power, and exercise cardiac power in a population based sample of Finnish male and female aged 30 to 47 years: the Cardiovascular Risk in Young Finns Study

scientific article

Determinants of left ventricular diastolic function-The Cardiovascular Risk in Young Finns Study

scientific article published on 24 March 2019

Determinants of serum 25(OH)D concentration in young and middle-aged adults. The Cardiovascular Risk in Young Finns Study

scientific article published on 23 April 2015

Determinants of short-term variation in arterial flow-mediated dilatation in healthy young men.

scientific article published in April 2006

Diagnostic accuracies of plasma creatinine, cystatin C, and glomerular filtration rate calculated by the Cockcroft-Gault and Levey (MDRD) formulas

scientific article

Diagnostic performance of plasma high sensitive C-reactive protein in detecting three-vessel coronary artery disease: modification by apolipoprotein E genotype

scientific article published on 01 January 2008

Diet does not explain the high prevalence of dyslipidaemia in paediatric renal transplant recipients

scientific article published on 15 November 2007

Dietary composition as a determinant of plasma asymmetric dimethylarginine in subjects with mild hypercholesterolemia

scientific article

Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques - Tampere Vascular Study

scientific article published on 27 January 2017

Differentially expressed genes and canonical pathways in the ascending thoracic aortic aneurysm - The Tampere Vascular Study

scientific article published on 21 September 2017

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Discovery and refinement of loci associated with lipid levels

scientific article

Discovery of mitochondrial DNA variants associated with genome-wide blood cell gene expression: a population-based mtDNA sequencing study

scientific article published on 01 April 2019

Discovery of novel heart rate-associated loci using the Exome Chip

scientific article

Distinct child-to-adult body mass index trajectories are associated with different levels of adult cardiometabolic risk

scientific article published on 01 June 2018

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

scientific article

Distinct variants at LIN28B influence growth in height from birth to adulthood

scientific article

Distribution and medical impact of loss-of-function variants in the Finnish founder population

scientific article

Do childhood infections affect labour market outcomes in adulthood and, if so, how?

scientific article published on 30 January 2020

Does Compassion Predict Blood Pressure and Hypertension? The Modifying Role of Familial Risk for Hypertension

scientific article published on 28 April 2020

Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT.

scientific article

Does education protect against depression? Evidence from the Young Finns Study using Mendelian randomization

scientific article published on 23 August 2018

Does high optimism protect against the inter-generational transmission of high BMI? The Cardiovascular Risk in Young Finns Study.

scientific article

Does higher education protect against obesity? Evidence using Mendelian randomization

scientific article published on 21 June 2017

Does neuregulin-1 play a role in Type A behavior? The cardiovascular risk in young Finns study

scientific article published on 17 September 2008

Dopamine 2 receptor C957T and catechol-o-methyltransferase Val158Met polymorphisms are associated with treatment response in electroconvulsive therapy

scientific article

Dopamine receptor D2 -141C Insertion/Deletion polymorphism in a Finnish population with schizophrenia

scientific article published in November 2003

Dopamine receptor D2 gene Taq1A (C32806T) polymorphism modifies the relationship between birth weight and educational attainment in adulthood: 21-year follow-up of the Cardiovascular Risk in Young Finns study

scientific article published in October 2007

Early childhood hospitalisation with infection and subclinical atherosclerosis in adulthood: the Cardiovascular Risk in Young Finns Study

scientific article published on 16 February 2015

East-west differences and migration in Finland: Association with cardiometabolic risk markers and IMT. The Cardiovascular Risk in Young Finns Study

scientific article published on 19 January 2016

Education leads to a more physically active lifestyle: Evidence based on Mendelian randomization

scientific article published on 16 March 2020

Effect of age, gender and cardiovascular risk factors on carotid distensibility during 6-year follow-up. The cardiovascular risk in Young Finns study

scholarly article by Juha Koskinen et al published October 2012 in Atherosclerosis

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Effect of common KCNE1 and SCN5A ion channel gene variants on T-wave alternans, a marker of cardiac repolarization, during clinical exercise stress test: the Finnish Cardiovascular Study

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Effect of high-dose statin treatment on plasma concentrations of endogenous nitric oxide synthase inhibitors

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Effect of long-term hormone replacement therapy on atherosclerosis progression in postmenopausal women relates to functional apolipoprotein e genotype

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Effect of long-term hormone replacement therapy on atherosclerosis progression in postmenopausal women relates to myeloperoxidase promoter polymorphism

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Effect of pravastatin on plasma sterols and oxysterols in men.

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Effect of the cessation of long-term hormone replacement therapy on plasma plasminogen activator inhibitor-1 and fibrinogen

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Effect of weight loss on liver free fatty acid uptake and hepatic insulin resistance

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Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach

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Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

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Effects of cognac on coronary flow reserve and plasma antioxidant status in healthy young men.

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Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence

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scholarly article by Tuomo Nieminen et al published February 2006 in Journal of Applied Physiology

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Elevated serum C-reactive protein levels and early arterial changes in healthy children

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Endothelial dysfunction and increased arterial intima-media thickness in children with type 1 diabetes

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Endothelial nitric oxide synthase genotype modulates the improvement of coronary blood flow by pravastatin: a placebo-controlled PET study

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Epidermal growth factor a61g polymorphism is associated with the age of onset of schizophrenia in male patients

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Epigenetic Link Between Statin Therapy and Type 2 Diabetes

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Epigenome-450K-wide methylation signatures of active cigarette smoking: the Young Finns Study

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Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

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Erratum: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

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Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

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Erratum: Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

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Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

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Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

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Estrogen Receptor 2 Polymorphism and Carotid Intima-Media Thickness

Estrogen receptor genotype modulates myocardial perfusion in young men.

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European lactase persistence genotype shows evidence of association with increase in body mass index

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Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia

Evidence HDAC9 genetic variant associated with ischemic stroke increases risk via promoting carotid atherosclerosis.

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Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

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Evidence of inbreeding depression on human height

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Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts

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Exercise-test-related heart rate variability and mortality

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Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

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Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

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Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure

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Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death

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Extended Serum Lipid Profile Predicting Long-Term Survival in Patients Treated for Abdominal Aortic Aneurysms

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Extensive phenotype data and machine learning in prediction of mortality in acute coronary syndrome - the MADDEC study

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FTO genotype is associated with body mass index after the age of seven years but not with energy intake or leisure-time physical activity

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Factors associated with six-year weight change in young and middle-aged adults in the Young Finns Study

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Fast 5-hour determination of angiotensin-converting enzyme genotypes from blood by SDS–PAGE using PhastSystem ⬇️

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Fasting Glucose and the Risk of Depressive Symptoms: Instrumental-Variable Regression in the Cardiovascular Risk in Young Finns Study.

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Fatty acid and cholesterol composition of the uterine artery intima in relation to menopausal status, age, and serum cholesterol

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Fatty liver is associated with blood pathways of inflammatory response, immune system activation and prothrombotic state in Young Finns Study.

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Fetal Growth and Preterm Birth Influence Cardiovascular Risk Factors and Arterial Health in Young Adults

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Fetal growth, omega-3 (n-3) fatty acids, and progression of subclinical atherosclerosis: preventing fetal origins of disease? The Cardiovascular Risk in Young Finns Study

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Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

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GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

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GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

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Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac repolarization in 3761 individuals from two independent populations

Gene expression profiles in Finnish twins with multiple sclerosis

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Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

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Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

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Gene-environment correlations in parental emotional warmth and intolerance: genome-wide analysis over two generations of the Young Finns Study

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Gene-environment interactions between education and body mass: Evidence from the UK and Finland

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Genes involved in systemic and arterial bed dependent atherosclerosis--Tampere Vascular study

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Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease

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Genetic Factors Explain a Major Fraction of the 50% Lower Lipoprotein(a) Concentrations in Finns

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Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

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Genetic Polymorphisms Associated With Constipation and Anticholinergic Symptoms in Patients Receiving Clozapine

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Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

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Genetic Variants in the DRD2 Gene Moderate the Relationship Between Stressful Life Events and Depressive Symptoms in Adults: Cardiovascular Risk in Young Finns Study

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Genetic analysis for a shared biological basis between migraine and coronary artery disease

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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

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Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and environmental perturbations lead to regulatory decoherence

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Genetic association study of childhood aggression across raters, instruments, and age

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Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

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Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits

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Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

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Genetic determinants of serum testosterone concentrations in men.

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Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

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Genetic endowments, parental resources and adult health: Evidence from the Young Finns Study.

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Genetic evidence of assortative mating in humans

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Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

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Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort

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Genetic polymorphism of sterol transporters in children with future gallstones

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Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents

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Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--

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Genetic studies of body mass index yield new insights for obesity biology

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Genetic study of circulating cytokines offers insight into the determinants, cascades and effects of systemic inflammation

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Genetic variant of the SREBF-1 gene is significantly related to cholesterol synthesis in man.

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Genetic variants and blood pressure in a population-based cohort: the Cardiovascular Risk in Young Finns study

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Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: the cardiovascular risk in young Finns study

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Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

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Genetic variants of TSLP and asthma in an admixed urban population

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Genetic variation in the hTAS2R38 taste receptor and food consumption among Finnish adults

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Genetically determined height and coronary artery disease

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Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study

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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

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Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population

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Genome-Wide Association Study Pinpoints a New Functional Apolipoprotein B Variant Influencing Oxidized Low-Density Lipoprotein Levels But Not Cardiovascular Events

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Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

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Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2.

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Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors

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Genome-wide analysis identifies 12 loci influencing human reproductive behavior

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Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

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Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

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Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

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Genome-wide association analysis identifies susceptibility loci for migraine without aura

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Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

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Genome-wide association and functional follow-up reveals new loci for kidney function

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Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

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Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

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Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

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Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

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Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association meta-analysis of childhood and adolescent internalising symptoms

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Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts.

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Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent

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Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

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Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.

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Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

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Genome-wide association study identifies 3 genomic loci significantly associated with serum levels of homoarginine: the AtheroRemo Consortium.

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Genome-wide association study identifies 74 loci associated with educational attainment

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Genome-wide association study identifies multiple loci influencing human serum metabolite levels

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Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns

scientific article published on 19 June 2019

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns:

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

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Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

scientific article published on 17 January 2018

Genome-wide association study of copy number variation with lung function identifies a novel signal of association near BANP for forced vital capacity

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Genome-wide association study of kidney function decline in individuals of European descent

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Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients

scientific article published on 04 July 2018

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.

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Genome-wide association study of sleep duration in the Finnish population

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Genome-wide association study of white-coat effect in hypertensive patients

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Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality

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Genome-wide associations for birth weight and correlations with adult disease

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Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

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Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

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Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

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Genome-wide meta-analysis identifies new susceptibility loci for migraine

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Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

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Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

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Genome-wide meta-analysis of common variant differences between men and women

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Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

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Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

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Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

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Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

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Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

scientific article published on 23 March 2016

Genomic, Transcriptomic, and Lipidomic Profiling Highlights the Role of Inflammation in Individuals With Low High-density Lipoprotein Cholesterol

HDL cholesterol efflux capacity is inversely associated with subclinical cardiovascular risk markers in young adults: The cardiovascular risk in Young Finns study

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HDL enhances oxidation of LDL in vitro in both men and women

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Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants.

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Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

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Health endowment and later-life outcomes in the labour market: Evidence using genetic risk scores and reduced-form models

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Heart rate variability derived from exercise ECG in the detection of coronary artery disease

scholarly article by Matti Virtanen et al published 18 September 2007 in Physiological Measurement

Heart rate variability is independently associated with C-reactive protein but not with Serum amyloid A. The Cardiovascular Risk in Young Finns Study

scholarly article by Atte Haarala et al published 17 February 2011 in European Journal of Clinical Investigation

Hepatic lipase C-480T genotype-dependent benefit from long-term hormone replacement therapy for atherosclerosis progression in postmenopausal women

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High birth weight is associated with obesity and increased carotid wall thickness in young adults: the cardiovascular risk in young Finns study

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High dose of red wine elicits enhanced inhibition of fibrinolysis

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High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis

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High perceived social support protects against the intergenerational transmission of obesity: The Cardiovascular Risk in Young Finns Study

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High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms

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High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels

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High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial

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High-throughput quantification of circulating metabolites improves prediction of subclinical atherosclerosis

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High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism

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Higher maternal body mass index is associated with an increased risk for later type 2 diabetes in offspring

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Higher step count is associated with greater bone mass and strength in women but not in men

Histaminergic gene polymorphisms associated with sedation in clozapine-treated patients

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Homocysteine and carotid atherosclerosis in chronic renal failure--the confounding effect of renal function

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Hundreds of variants clustered in genomic loci and biological pathways affect human height

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IL-18 gene polymorphism, cardiovascular mortality and coronary artery disease

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INSIG2 polymorphism and weight gain, dyslipidemia and serum adiponectin in Finnish patients with schizophrenia treated with clozapine

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Ideal cardiovascular health in childhood and cardiometabolic outcomes in adulthood: the Cardiovascular Risk in Young Finns Study

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Identification of a Genetic Variation in ERAP1 Aminopeptidase that Prevents Human Cytomegalovirus miR-UL112-5p-Mediated Immunoevasion

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Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

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Identification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure

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IgA levels are predictors of mortality in Finnish nonagenarians

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Impact of Ideal Cardiovascular Health in Childhood on the Retinal Microvasculature in Midadulthood: Cardiovascular Risk in Young Finns Study ⬇️

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Impact of blood pressure on retinal microvasculature architecture across the lifespan: the Young Finns Study

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Impact of fetal growth and preterm birth on the retinal microvasculature in mid-adulthood

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Impact of long-term hormone replacement therapy on in vivo and in vitro markers of lipid oxidation

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Impaired exercise capacity predicts sudden cardiac death in a low-risk population: Enhanced specificity with heightened T-wave alternans

Importance of regional specificity of T-wave alternans in assessing risk for cardiovascular mortality and sudden cardiac death during routine exercise testing

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Increased Body Mass Index in Parent-Child Dyads Predicts the Offspring Risk of Meeting Bariatric Surgery Criteria

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Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration

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Increased Liver Fatty Acid Uptake Is Partly Reversed and Liver Fat Content Normalized After Bariatric Surgery

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Increased calcium intake reduces plasma cholesterol and improves vasorelaxation in experimental renal failure

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Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

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Increased serum matrix metalloproteinase 9 levels in systemic lupus erythematosus patients with neuropsychiatric manifestations and brain magnetic resonance imaging abnormalities

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Increased tooth brushing frequency is associated with reduced gingival pocket bacterial diversity in patients with intracranial aneurysms

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Indoleamine 2,3-dioxygenase activation and depressive symptoms: results from the Young Finns Study

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Infection-Related Hospitalization in Childhood and Adult Metabolic Outcomes

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Inflammation, adiposity, and mortality in the oldest old.

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Influence of Child and Adult Elevated Blood Pressure on Adult Arterial Stiffness: The Cardiovascular Risk in Young Finns Study

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Influence of Genetic Variation in PDE3A on Endothelial Function and Stroke

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Influence of apolipoprotein E polymorphism on serum lipid and lipoprotein changes: a 21-year follow-up study from childhood to adulthood. The Cardiovascular Risk in Young Finns Study

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Influence of early-lifebody mass index and systolic blood pressure on left ventricle in adulthood - The Cardiovascular Risk in Young Finns Study

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Insulin and BMI as predictors of adult type 2 diabetes mellitus

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Insulin resistance, LDL particle size, and LDL susceptibility to oxidation in pediatric kidney and liver recipients

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Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

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Integrative approaches for large-scale transcriptome-wide association studies

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Interaction between NOTCH4 and catechol-O-methyltransferase genotypes in schizophrenia patients with poor response to typical neuroleptics

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Interaction between angiotensin-converting enzyme and catechol-O-methyltransferase genotypes in schizophrenics with poor response to conventional neuroleptics

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Interaction between matrix metalloproteinase 3 and the epsilon4 allele of apolipoprotein E increases the risk of Alzheimer's disease in Finns

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Interaction between two HTR2A polymorphisms and gender is associated with treatment response in MDD.

scientific article published on 29 June 2011

Interaction of tumor necrosis alpha - G308A and epidermal growth factor gene polymorphisms in early-onset schizophrenia

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Interactions between genetic variants and dietary lipid composition: effects on circulating LDL cholesterol in children

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Interactions of functional apolipoprotein E gene promoter polymorphisms with smoking on aortic atherosclerosis

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Interleukin 18 gene promoter polymorphism: a link between hypertension and pre-hospital sudden cardiac death: the Helsinki Sudden Death Study

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Interleukin 1B gene polymorphism is associated with baseline C-reactive protein levels in healthy individuals.

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Interleukin-1 receptor antagonist, interleukin-6, and C-reactive protein as predictors of mortality in nonagenarians: the vitality 90+ study

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Interleukin-18 gene polymorphism and markers of subclinical atherosclerosis. The Cardiovascular Risk in Young Finns Study

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Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: the Helsinki Sudden Death Study

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Interleukin-1B genotype modulates the improvement of coronary artery reactivity by lipid-lowering therapy with pravastatin: a placebo-controlled positron emission tomography study in young healthy men.

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Interleukin-6 and microRNA profiles induced by oral bacteria in human atheroma derived and healthy smooth muscle cells

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Interleukin-6 gene polymorphism, chronic stress and atherosclerosis

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Interleukin-6 modulates plasma cholesterol and C-reactive protein concentrations in nonagenarians

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Interleukin-6 promoter polymorphism and cardiovascular risk factors: the Health 2000 Survey.

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International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents

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Intracranial aneurysm risk locus 5q23.2 is associated with elevated systolic blood pressure

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Intraneuronal Abeta immunoreactivity is not a predictor of brain amyloidosis-beta or neurofibrillary degeneration

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Is 5-HTTLPR linked to the response of selective serotonin reuptake inhibitors in MDD?

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Is It Good To Be Good? Dispositional Compassion and Health Behaviors

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Is dispositional optimism or dispositional pessimism predictive of ideal cardiovascular health? The Young Finns Study

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Kindlin 3 (FERMT3) is associated with unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins in all major arterial beds

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Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

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Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

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Large-scale association analysis identifies new risk loci for coronary artery disease

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Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

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Left ventricular ejection fraction adds value over the GRACE score in prediction of 6-month mortality after ACS: the MADDEC study

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Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene and changes in serum lipids during a family-based counselling intervention among school-aged children with a family history of CVD.

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Leukocyte telomere length is inversely associated with arterial wave reflection in 566 normotensive and never-treated hypertensive subjects

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Levels of asymmetrical dimethylarginine are predictive of brachial artery flow-mediated dilation 6 years later. The Cardiovascular Risk in Young Finns Study

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Life-course risk factor levels and coronary artery calcification. The Cardiovascular Risk in Young Finns Study

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Life-time risk factors and progression of carotid atherosclerosis in young adults: the Cardiovascular Risk in Young Finns study

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Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study

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Lifetime fruit and vegetable consumption and arterial pulse wave velocity in adulthood: the Cardiovascular Risk in Young Finns Study

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Lifetime risk factors and arterial pulse wave velocity in adulthood: the cardiovascular risk in young Finns study

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Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23

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Lipidomic architecture shared by subclinical markers of osteoporosis and atherosclerosis: The Cardiovascular Risk in Young Finns Study

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Lipoprotein Subclass Profiling Reveals Pleiotropy in the Genetic Variants of Lipid Risk Factors for Coronary Heart Disease

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Lipoprotein docosapentaenoic acid is associated with serum matrix metalloproteinase-9 concentration

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Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition

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Liver and pancreatic fat content and metabolism in healthy monozygotic twins with discordant physical activity

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Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes

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Long-term leisure-time physical activity and serum metabolome

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Long-term outcome of intraventricular conduction delays in the general population

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Long-term prognostic significance of the ST level and ST slope in the 12‑lead ECG in the general population

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Longitudinal Associations of Explosive and Adventurous Temperament Profiles With Character Development: The Modifying Effects of Social Support and Attachment

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Longitudinal association of a body mass index (BMI) genetic risk score with growth and BMI changes across the life course: The Cardiovascular Risk in Young Finns Study

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Longitudinal associations of temperament and character with paranoid ideation: A population-based study

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Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study

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Longitudinal study of circulating oxidized LDL and HDL and fatty liver: the Cardiovascular Risk in Young Finns Study

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Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease

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Low serum adiponectin levels in childhood and adolescence predict increased intima-media thickness in adulthood. The Cardiovascular Risk in Young Finns Study

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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

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Maternal and infant characteristics connected to shared pleasure in dyadic interaction

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Melanocortin 1 Receptor Signaling Regulates Cholesterol Transport in Macrophages

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Melatonin pathway genes are associated with progressive subtypes and disability status in multiple sclerosis among Finnish patients

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Mendelian Randomization Suggests No Causal Association Between C-reactive Protein and Carotid Intima-media Thickness in the Young Finns Study

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

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Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

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Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

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Meta-analysis of exome array data identifies six novel genetic loci for lung function

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Meta-analysis of exome array data identifies six novel genetic loci for lung function

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

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Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

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Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

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Metabolic Effects Of Risk Alleles In PNPLA3, TM6SF2, GCKR, And LYPLAL1 Inform About Heterogeneity Of Non-Alcoholic Fatty Liver Disease

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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

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Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

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Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

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Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy

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NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality

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Neuropeptide Y signal peptide Pro7 substitution protects against coronary artery atherosclerosis: the Helsinki Sudden Death Study

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New evidence from plasma ceramides links apoE polymorphism to greater risk of coronary artery disease in Finnish adults

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No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

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No association of nineteen COX-2 gene variants to preclinical markers of atherosclerosis The Cardiovascular Risk in Young Finns Study

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Novel genes for autism implicate both excitatory and inhibitory cell lineages in risk

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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

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Oxidized LDL autoantibodies are related to apolipoprotein E phenotype, independently of postprandial change in plasma triglycerides and LDL size, among patients with angiographically verified coronary artery disease and healthy controls

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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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Physical Activity Associates with Muscle Insulin Sensitivity Postbariatric Surgery

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Plasma Concentrations of Afamin Are Associated With Prevalent and Incident Type 2 Diabetes: A Pooled Analysis in More Than 20,000 Individuals

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Plasma asymmetric dimethylarginine modifies the effect of pravastatin on myocardial blood flow in young adults

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Plasma concentrations of asymmetric-dimethyl-arginine in type 2 diabetes associate with glycemic control and glomerular filtration rate but not with risk factors of vasculopathy

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Plasma-soluble CD40 is related to cholesterol metabolism in patients with moderate hypercholesterolemia

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Plasminogen activator inhitor-1 associates with cardiovascular risk factors in healthy young adults in the Cardiovascular Risk in Young Finns Study

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Prediction of Adulthood Obesity Using Genetic and Childhood Clinical Risk Factors in the Cardiovascular Risk in Young Finns Study

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Pro-opiomelanocortin and its Processing Enzymes Associate with Plaque Stability in Human Atherosclerosis - Tampere Vascular Study

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Prognostic implications of quantitative ST-segment characteristics and T-wave amplitude for cardiovascular mortality in a general population from the Health 2000 Survey

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Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses

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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

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Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

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Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

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Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

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Pulse Wave Velocity Predicts the Progression of Blood Pressure and Development of Hypertension in Young Adults

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Pulse wave velocity is related to exercise blood pressure response in young adults. The Cardiovascular Risk in Young Finns Study

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QRS-T morphology measured from exercise electrocardiogram as a predictor of cardiac mortality

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RGS4 polymorphism and response to electroconvulsive therapy in major depressive disorder

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RNA-sequencing reveals that STRN, ZNF484 and WNK1 add to the value of mitochondrial MT-COI and COX10 as markers of unstable coronary artery disease

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Rapid and accurate detection of urinary pathogens by mobile IMS-based electronic nose: a proof-of-principle study

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Rapid apolipoprotein E genotyping from mailed buccal swabs ⬇️

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Rare and low-frequency coding variants alter human adult height

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Reciprocal relationships between psychosocial work characteristics and sleep problems: A two-wave study

Reference Values for Echocardiography in Middle-Aged Population: The Cardiovascular Risk in Young Finns Study

Regional Differences in Apolipoprotein E Polymorphism in Finland

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Regulatory variant of the TPH2 gene and early life stress are associated with heightened attention to social signals of fear in infants

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Relation of Apolipoprotein E Polymorphism to Markers of Early Atherosclerotic Changes in Young Adults

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Relation of intraventricular conduction delay to risk of new-onset heart failure and structural heart disease in the general population

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Relation of positive T wave in lead aVR to risk of cardiovascular mortality

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Relations of APOE promoter polymorphisms to LDL cholesterol and markers of subclinical atherosclerosis in young adults

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Relationship between leptin and C-reactive protein in young Finnish adults

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Reply

Response to Letters Regarding Article, “Bacterial Signatures in Thrombus Aspirates of Patients With Myocardial Infarction”

Risk factors for aortic atherosclerosis determined by transesophageal echocardiography in patients with CRF.

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Risk of obesity and metabolic syndrome associated with FTO gene variants discloses clinically relevant gender difference among Turks

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Role of Conventional Childhood Risk Factors Versus Genetic Risk in the Development of Type 2 Diabetes and Impaired Fasting Glucose in Adulthood: The Cardiovascular Risk in Young Finns Study

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SERT and NET polymorphisms, temperament and antidepressant response

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SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

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Scrutiny of the CHRNA5-CHRNA3-CHRNB4 smoking behavior locus reveals a novel association with alcohol use in a Finnish population based study

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Sequentially combined estradiol valerate plus levonorgestrel therapy decreases 18:1 trans-fatty acid content of plasma lipids in healthy postmenopausal women

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Seropositivity for Helicobacter pylori antibodies is associated with lower occurrence of venous bypass graft occlusion

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Serotonin Receptor 2A Gene and the Influence of Childhood Maternal Nurturance on Adulthood Depressive Symptoms

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Serotonin receptor 1B genotype and hostility, anger and aggressive behavior through the lifespan: the Young Finns study

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Serum TRACP 5b is a useful marker for monitoring alendronate treatment: comparison with other markers of bone turnover

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Serum fatty acid profile in celiac disease patients before and after a gluten-free diet.

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Serum fatty acid profile in subjects with irritable bowel syndrome

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Serum lipids in children 3 to 5 years after kidney, liver, and heart transplantation

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Seventy-five genetic loci influencing the human red blood cell

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Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates

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Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

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Simplified definitions of elevated pediatric blood pressure and high adult arterial stiffness

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Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

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Smooth muscle cells in human atherosclerosis: Proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease

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Socioeconomic Status, Cardiovascular Risk Factors, and Subclinical Atherosclerosis in Young Adults

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Statin Pharmacogenomics: Lipid Response and Cardiovascular Outcomes

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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

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Subsequent Event Risk in Individuals With Established Coronary Heart Disease

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Subtle increases in heart size persist into adulthood in growth restricted babies: the Cardiovascular Risk in Young Finns Study

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Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis

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Suppression of immune system genes by methylprednisolone in exacerbations of multiple sclerosis. Preliminary results

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Sympathetic activity-associated periodic repolarization dynamics predict mortality following myocardial infarction

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Sympathetic activity–associated periodic repolarization dynamicspredict mortality following myocardial infarction.

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Synthesis and absorption of cholesterol in Finnish boys by serum non-cholesterol sterols: the cardiovascular risk in Young Finns Study

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Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia

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Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population

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Systemic hemodynamics in young adults with the metabolic syndrome: The Cardiovascular Risk in Young Finns Study

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Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

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TPH1 218A/C polymorphism is associated with major depressive disorder and its treatment response

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TPH2 polymorphisms may modify clinical picture in treatment-resistant depression

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Talin and vinculin are downregulated in atherosclerotic plaque; Tampere Vascular Study

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Television viewing and fatty liver in early midlife. The Cardiovascular Risk in Young Finns Study

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Temperament profiles, 5-HT2A genotype, and response to treatment with SSRIs in major depression

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Temperamental Activity and Epidermal Growth Factor A61G Polymorphism in Finnish Adults

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The APOE -219G/T and +113G/C polymorphisms affect insulin resistance among Turks

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The Association Between Social Support, Body Mass Index and Increased Risk of Prediabetes: the Cardiovascular Risk in Young Finns Study

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The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection

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The Combined Effect of Common Genetic Risk Variants on Circulating Lipoproteins Is Evident in Childhood: A Longitudinal Analysis of the Cardiovascular Risk in Young Finns Study

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The Decreasing Prevalence of Nonrefractive Visual Impairment in Older Europeans

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The Duke treadmill score with bicycle ergometer: Exercise capacity is the most important predictor of cardiovascular mortality

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The Effect of Weight on Labor Market Outcomes: an Application of Genetic Instrumental Variables ⬇️

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The Finnish Cardiovascular Study (FINCAVAS): characterising patients with high risk of cardiovascular morbidity and mortality

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The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

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The Polygenic and Monogenic Basis of Blood Traits and Diseases

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The SGLT2 Inhibitor Dapagliflozin Reduces Liver Fat but Does Not Affect Tissue Insulin Sensitivity: A Randomized, Double-Blind, Placebo-Controlled Study With 8-Week Treatment in Type 2 Diabetes Patients

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The Young Finns Study

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The association of myeloperoxidase promoter polymorphism with carotid atherosclerosis is abolished in patients with type 2 diabetes

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The effect of apolipoprotein E polymorphism on serum metabolome - a population-based 10-year follow-up study

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The effect of long-term microcrystalline chitosan therapy on plasma lipids and glucose concentrations in subjects with increased plasma total cholesterol: a randomised placebo-controlled double-blind crossover trial in healthy men and women

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The effect of mannan-binding lectin variant alleles on coronary artery reactivity in healthy young men

The effect of weight on labor market outcomes: An application of genetic instrumental variables

The effects of adult-type hypolactasia on body height growth and dietary calcium intake from childhood into young adulthood: a 21-year follow-up study--the Cardiovascular Risk in Young Finns Study

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The effects of apoA-I/C-III/A-IV, apoE and apoB polymorphisms on carotid artery intima-media thickness

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The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

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The influence of urban/rural residency on depressive symptoms is moderated by the serotonin receptor 2A gene

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The interaction between serotonin receptor 2A and catechol-O-methyltransferase gene polymorphisms is associated with the novelty-seeking subscale impulsiveness

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The molecular genetic architecture of self-employment

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