List of works - Agata Smogorzewska

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

scientific article

TRF2 Protects Human Telomeres from End-to-End Fusions

scientific journal article

DNA damage foci at dysfunctional telomeres

scientific article (publication date: 2 September 2003)

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

scientific article published in October 1997

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

scientific article

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

scientific article

Regulation of telomerase by telomeric proteins

scientific article (publication date: 2004)

Senescence Induced by Altered Telomere State, Not Telomere Loss

scientific article

Control of human telomere length by TRF1 and TRF2

scientific article published in March 2000

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

scientific article

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair

scientific article

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

scientific article

Homologous recombination generates T-loop-sized deletions at human telomeres

scientific journal article

Cancer proliferation gene discovery through functional genomics.

scientific article

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

scientific article

Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling

scientific article

A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response

scientific article published on 19 February 2012

Different telomere damage signaling pathways in human and mouse cells

scientific article published on August 2002

Mutations of the SLX4 gene in Fanconi anemia

scientific article

DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2

scientific journal article

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

scientific article published on 19 October 2008

FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair

scientific article

Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.

scientific article published in July 2015

Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency

scientific article published on 22 February 2012

A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination

scientific journal article

Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence

scientific article

Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4.

scientific article published on 23 October 2012

Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway

scientific article

SnapShot: Fanconi anemia and associated proteins

scientific article

Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia

scientific article published on 25 June 2015

Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions

scientific article

Massively parallel sequencing, aCGH, and RNA-Seq technologies provide a comprehensive molecular diagnosis of Fanconi anemia.

scientific article published on 23 April 2013

Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance

scientific article

Ubiquitylation and the Fanconi anemia pathway

scientific article published on 19 May 2011

DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1

scientific article

Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency

scientific article published on 17 April 2017

Postoperative clinical radiosensitivity in patients with fanconi anemia and head and neck squamous cell carcinoma

scientific article

Comprehensive analysis of pathogenic deletion variants in Fanconi anemia genes

scientific article published on November 2014

Natural history and management of Fanconi anemia patients with head and neck cancer: A 10-year follow-up

scientific article published on 20 October 2015

Advances in understanding DNA processing and protection at stalled replication forks

scientific article published on 22 January 2019

Assessment of SLX4 Mutations in Hereditary Breast Cancers

scientific article

Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity.

scientific article published on 15 December 2017

Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction

scientific article published on March 2016

S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.

scientific article published on 28 January 2017

A comprehensive approach to identification of pathogenic FANCA variants in Fanconi anemia patients and their families.

scientific article published on 2 November 2017

Paraprotein interference in automated chemistry analyzers

scientific article

Somatic mosaicism of an intragenic FANCB duplication in both fibroblast and peripheral blood cells observed in a Fanconi anemia patient leads to milder phenotype.

scientific article published on 30 November 2017

Effect of fondaparinux on coagulation assays: results of College of American Pathologists proficiency testing

scientific article published on 01 November 2006

Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program

scientific article published in October 2017

Postmortem urine immunoassay showing false-positive phencyclidine reactivity in a case of fatal tramadol overdose

scientific article published on 01 December 2006

List of works by Agata Smogorzewska

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

TRF2 Protects Human Telomeres from End-to-End Fusions

DNA damage foci at dysfunctional telomeres

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

Regulation of telomerase by telomeric proteins

Senescence Induced by Altered Telomere State, Not Telomere Loss

Control of human telomere length by TRF1 and TRF2

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

Homologous recombination generates T-loop-sized deletions at human telomeres

Cancer proliferation gene discovery through functional genomics.

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling

A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response

Different telomere damage signaling pathways in human and mouse cells

Mutations of the SLX4 gene in Fanconi anemia

DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair

Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.

Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency

A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination

Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence

Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4.

Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway

SnapShot: Fanconi anemia and associated proteins

Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia

Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions

Massively parallel sequencing, aCGH, and RNA-Seq technologies provide a comprehensive molecular diagnosis of Fanconi anemia.

Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance

Ubiquitylation and the Fanconi anemia pathway

DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1

Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency

Postoperative clinical radiosensitivity in patients with fanconi anemia and head and neck squamous cell carcinoma

Comprehensive analysis of pathogenic deletion variants in Fanconi anemia genes

Natural history and management of Fanconi anemia patients with head and neck cancer: A 10-year follow-up

Advances in understanding DNA processing and protection at stalled replication forks

Assessment of SLX4 Mutations in Hereditary Breast Cancers

Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity.

Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction

S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.

A comprehensive approach to identification of pathogenic FANCA variants in Fanconi anemia patients and their families.

Paraprotein interference in automated chemistry analyzers

Somatic mosaicism of an intragenic FANCB duplication in both fibroblast and peripheral blood cells observed in a Fanconi anemia patient leads to milder phenotype.

Effect of fondaparinux on coagulation assays: results of College of American Pathologists proficiency testing

Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program

Postmortem urine immunoassay showing false-positive phencyclidine reactivity in a case of fatal tramadol overdose