Search filters

List of works by Patrick Vallance

A role for Dimethylarginine Dimethylaminohydrolase 1 (DDAH1) in mammalian development

scientific article published in January 2010

Asymmetric dimethylarginine (ADMA): a key regulator of nitric oxide synthase

scientific article

Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase

scientific article

Blocking NO synthesis: how, where and why?

scientific article

Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway

scientific article published on 22 April 2004

Cardiovascular risk and diabetes. Are the methods of risk prediction satisfactory?

scientific article published on December 2004

Cardiovascular tests: use & limits of biochemical markers - therapeutic measurements of ADMA involved in cardiovascular disorders.

scientific article

Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males

scientific article (publication date: 5 April 2011)

Chronic stress accelerates atherosclerosis in the apolipoprotein E deficient mouse

scientific article

Data Sharing as Part of the Normal Scientific Process: A View from the Pharmaceutical Industry

scientific article

Dimethylarginine dimethylaminohydrolase activity modulates ADMA levels, VEGF expression, and cell phenotype

scientific article published in September 2003

Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence

scientific article

Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis.

scientific article

Disruption of methylarginine metabolism impairs vascular homeostasis

scientific article

Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis

scientific article

Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA.

scientific article

Endogenous production of nitric oxide synthase inhibitors

scientific article

Endothelial NO synthase genotype and risk of preeclampsia: a multicenter case-control study

scientific article

Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia

scientific article published in May 2003

Endothelium-dependent and -independent vascular dysfunction in type 1 diabetes: role of conventional risk factors, sex, and glycemic control

scientific article published on 24 April 2003

Human cytomegalovirus seropositivity is associated with impaired vascular function

scientific article published on 04 August 2003

Increasing dimethylarginine levels are associated with adverse clinical outcome in severe alcoholic hepatitis.

scientific article published in January 2007

Industry-Academic Relationship in a New Era of Drug Discovery

scientific article

Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability

scientific article

Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress

scientific article published in October 2004

Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by hypobaric hypoxia

scientific article

Nitric oxide: therapeutic opportunities

scientific article

Over-expression of GTP-cyclohydrolase 1 feedback regulatory protein attenuates LPS and cytokine-stimulated nitric oxide production

scientific article

Prevention of inflammation-induced endothelial dysfunction: a novel vasculo-protective action of aspirin

scientific article (publication date: 4 June 2002)

Protease-activated receptor 2-mediated vasodilatation in humans in vivo: role of nitric oxide and prostanoids

scientific article (publication date: 25 February 2003)

Pulmonary hypertension in a GTP-cyclohydrolase 1-deficient mouse

scientific journal article

Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2.

scientific article

Risk of deep vein thrombosis and pulmonary embolism after acute infection in a community setting

scientific article published on April 2006

Risk of myocardial infarction and stroke after acute infection or vaccination

scientific article published on December 2004

S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase

scientific article

Science as a public enterprise: the case for open data

scientific article

Secure use of individual patient data from clinical trials

scientific article

Selective substrate-based inhibitors of mammalian dimethylarginine dimethylaminohydrolase.

scientific article published on July 2005

The DDAH/ADMA/NOS pathway

scientific article published on December 2003

The Social Media Index as an Indicator of Quality for Emergency Medicine Blogs: A METRIQ Study

article

The effects of hormone replacement therapy on endothelial function in women with Turner's syndrome

scientific article published in May 2002

The future of pharmacology

scientific article

Training in paediatric clinical pharmacology in the UK.

scientific article published on August 2004

all-trans-Retinoic acid increases nitric oxide synthesis by endothelial cells: a role for the induction of dimethylarginine dimethylaminohydrolase.

scientific article

Paulina is supported by:

About Paulina

Help