List of works - James Ironside

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

scientific article published on 01 October 1996

Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent

scientific article published in October 1997

Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient

scientific article

Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples.

scientific article

Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans

scientific article published on December 1999

Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy

scientific article published in The Lancet

Prevalence of lymphoreticular prion protein accumulation in UK tissue samples.

scientific article published in July 2004

BSE transmission to macaques

scientific article published in Nature

A prion protein epitope selective for the pathologically misfolded conformation

scientific article

Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study

scientific article published in April 2003

Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia

scientific article published on 12 January 2010

Predicting susceptibility and incubation time of human-to-human transmission of vCJD.

scientific article published in May 2006

Molecular classification of sporadic Creutzfeldt-Jakob disease.

scientific article published in June 2003

Mutations of the prion protein gene phenotypic spectrum

scientific article (publication date: November 2002)

Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease

scientific article published in The Lancet

A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy

scientific article published on December 1999

Prion protein accumulation and neuroprotection in hypoxic brain damage

scientific article

Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: phase 3 study

scientific article published on 27 March 2015

Molecular assessment of the potential transmissibilities of BSE and scrapie to humans.

scientific article published in July 1997

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

scientific article published on 10 December 2015

Staging/typing of Lewy body related alpha-synuclein pathology: a study of the BrainNet Europe Consortium.

scientific article published on 28 March 2009

Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey

scientific article

Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

scientific article published in The Lancet

Diagnostic criteria for sporadic Creutzfeldt-Jakob disease

scientific article published in September 1996

Phenotypic variability of Gerstmann-Sträussler-Scheinker disease is associated with prion protein heterogeneity.

scientific article published in October 1998

The pulvinar sign on magnetic resonance imaging in variant Creutzfeldt-Jakob disease

scientific article

Detection of variant Creutzfeldt-Jakob disease infectivity in extraneural tissues

scientific article published in The Lancet

Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene

scientific article

Adaptation of the bovine spongiform encephalopathy agent to primates and comparison with Creutzfeldt-- Jakob disease: implications for human health

scholarly article

Primary postoperative chemotherapy without radiotherapy for intracranial ependymoma in children: the UKCCSG/SIOP prospective study

scientific article

Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study

scientific article

Peripheral tissue involvement in sporadic, iatrogenic, and variant Creutzfeldt-Jakob disease: an immunohistochemical, quantitative, and biochemical study

scientific article

Human immunodeficiency virus and the brain: investigation of virus load and neuropathologic changes in pre-AIDS subjects.

scientific article published in October 1993

Pre-symptomatic detection of prions by cyclic amplification of protein misfolding.

scientific article published in January 2005

Detection of type 1 prion protein in variant Creutzfeldt-Jakob disease

scientific article

Consensus classification of human prion disease histotypes allows reliable identification of molecular subtypes: an inter-rater study among surveillance centres in Europe and USA

scientific article published on 30 June 2012

Tetracyclines affect prion infectivity

scientific article

Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc

scholarly article

Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium

scientific article

Diagnosis of new variant Creutzfeldt-Jakob disease

scientific article

The apolipoprotein E epsilon2 allele and the pathological features in cerebral amyloid angiopathy-related hemorrhage

scientific article published in July 1999

High frequency of apolipoprotein E ?2 Allele in hemorrhage due to cerebral amyloid angiopathy

scientific article published on 01 June 1997

Laboratory diagnosis of variant Creutzfeldt-Jakob disease.

scientific article

Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion

scientific article

Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies.

scientific article published on 28 August 2016

Prion protein heterogeneity in sporadic but not variant Creutzfeldt-Jakob disease: UK cases 1991-2002.

scientific article published in June 2004

Variant Creutzfeldt-Jakob disease: prion protein genotype analysis of positive appendix tissue samples from a retrospective prevalence study

scientific article

Outcome for patients with metastatic (M2-3) medulloblastoma treated with SIOP/UKCCSG PNET-3 chemotherapy

scientific article

Neuronal apoptosis in Creutzfeldt-Jakob disease

scientific article published in April 1999

Changing a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers

scientific article

List of works by James Ironside

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent

Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient

Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples.

Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans

Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy

Prevalence of lymphoreticular prion protein accumulation in UK tissue samples.

BSE transmission to macaques

A prion protein epitope selective for the pathologically misfolded conformation

Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study

Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia

Predicting susceptibility and incubation time of human-to-human transmission of vCJD.

Molecular classification of sporadic Creutzfeldt-Jakob disease.

Mutations of the prion protein gene phenotypic spectrum

Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease

A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy

Prion protein accumulation and neuroprotection in hypoxic brain damage

Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: phase 3 study

Molecular assessment of the potential transmissibilities of BSE and scrapie to humans.

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

Staging/typing of Lewy body related alpha-synuclein pathology: a study of the BrainNet Europe Consortium.

Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey

Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

Diagnostic criteria for sporadic Creutzfeldt-Jakob disease

Phenotypic variability of Gerstmann-Sträussler-Scheinker disease is associated with prion protein heterogeneity.

The pulvinar sign on magnetic resonance imaging in variant Creutzfeldt-Jakob disease

Detection of variant Creutzfeldt-Jakob disease infectivity in extraneural tissues

Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene

Adaptation of the bovine spongiform encephalopathy agent to primates and comparison with Creutzfeldt-- Jakob disease: implications for human health

Primary postoperative chemotherapy without radiotherapy for intracranial ependymoma in children: the UKCCSG/SIOP prospective study

Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study

Peripheral tissue involvement in sporadic, iatrogenic, and variant Creutzfeldt-Jakob disease: an immunohistochemical, quantitative, and biochemical study

Human immunodeficiency virus and the brain: investigation of virus load and neuropathologic changes in pre-AIDS subjects.

Pre-symptomatic detection of prions by cyclic amplification of protein misfolding.

Detection of type 1 prion protein in variant Creutzfeldt-Jakob disease

Consensus classification of human prion disease histotypes allows reliable identification of molecular subtypes: an inter-rater study among surveillance centres in Europe and USA

Tetracyclines affect prion infectivity

Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc

Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium

Diagnosis of new variant Creutzfeldt-Jakob disease

The apolipoprotein E epsilon2 allele and the pathological features in cerebral amyloid angiopathy-related hemorrhage

High frequency of apolipoprotein E ?2 Allele in hemorrhage due to cerebral amyloid angiopathy

Laboratory diagnosis of variant Creutzfeldt-Jakob disease.

Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion

Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies.

Prion protein heterogeneity in sporadic but not variant Creutzfeldt-Jakob disease: UK cases 1991-2002.

Variant Creutzfeldt-Jakob disease: prion protein genotype analysis of positive appendix tissue samples from a retrospective prevalence study

Outcome for patients with metastatic (M2-3) medulloblastoma treated with SIOP/UKCCSG PNET-3 chemotherapy

Neuronal apoptosis in Creutzfeldt-Jakob disease

Changing a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers