List of works - Oluf Borbye Pedersen

A human gut microbial gene catalogue established by metagenomic sequencing

scientific article

Enterotypes of the human gut microbiome

scientific article

A metagenome-wide association study of gut microbiota in type 2 diabetes

scientific article (publication date: 4 October 2012)

Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes

scientific article

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

Richness of human gut microbiome correlates with metabolic markers

scientific article (publication date: 29 August 2013)

Effect of a multifactorial intervention on mortality in type 2 diabetes

scientific article published in February 2008

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

scientific article

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

scientific article published on 2 December 2015

An integrated catalog of reference genes in the human gut microbiome

scientific article

Two variants on chromosome 17 confer prostate cancer risk and the one in TCF2 protects against type 2 diabetes

article

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

article

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

scientific article

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

article

Many sequence variants affecting diversity of adult human height

scientific article published in May 2008

Human gut microbes impact host serum metabolome and insulin sensitivity

scientific article

Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

scientific article published on 6 July 2014

Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation

scientific article published on 17 October 2007

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

scientific article published on 6 September 2009

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

scientific article

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

scientific article

High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia

scientific article published on 13 November 2007

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

Metagenomic species profiling using universal phylogenetic marker genes

scientific article

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes

scientific article published on 5 May 2009

Efficacy of dofetilide in the treatment of atrial fibrillation-flutter in patients with reduced left ventricular function: a Danish investigations of arrhythmia and mortality on dofetilide (diamond) substudy

scientific article published in July 2001

Greenlandic Inuit show genetic signatures of diet and climate adaptation

scientific article

Common nonsynonymous variants in PCSK1 confer risk of obesity

article

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies

scientific article published on 7 September 2007

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes

scientific article

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

scientific article

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

scientific article published on 05 September 2010

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

scientific article published on 25 September 2011

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

scientific article published in October 1993

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

scientific article published on 08 October 2018

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

scientific article published on 2 December 2012

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study

scientific article

List of works by Oluf Borbye Pedersen

A human gut microbial gene catalogue established by metagenomic sequencing

Enterotypes of the human gut microbiome

A metagenome-wide association study of gut microbiota in type 2 diabetes

Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Richness of human gut microbiome correlates with metabolic markers

Effect of a multifactorial intervention on mortality in type 2 diabetes

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

An integrated catalog of reference genes in the human gut microbiome

Two variants on chromosome 17 confer prostate cancer risk and the one in TCF2 protects against type 2 diabetes

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

The genetic architecture of type 2 diabetes

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

Many sequence variants affecting diversity of adult human height

Human gut microbes impact host serum metabolome and insulin sensitivity

Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

Metagenomic species profiling using universal phylogenetic marker genes

Rare and low-frequency coding variants alter human adult height

Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes

Efficacy of dofetilide in the treatment of atrial fibrillation-flutter in patients with reduced left ventricular function: a Danish investigations of arrhythmia and mortality on dofetilide (diamond) substudy

Greenlandic Inuit show genetic signatures of diet and climate adaptation

Common nonsynonymous variants in PCSK1 confer risk of obesity

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study