Search filters

List of works by H. Robert Horvitz

"Joy of the worm".

scientific article published on October 1990

3-Ketoacyl thiolase delays aging ofCaenorhabditis elegansand is required for lifespan extension mediated bysir-2.1

scientific article published on October 18, 2010

A Caenorhabditis elegans protein with a PRDM9-like SET domain localizes to chromatin-associated foci and promotes spermatocyte gene expression, sperm production and fertility.

scientific article published on 27 April 2018

A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans

scientific article published in January 1994

A cell that dies during wild-type C. elegans development can function as a neuron in a ced-3 mutant

scientific article published on December 1987

A dual mechanosensory and chemosensory neuron in Caenorhabditis elegans

scientific article

A first insight into the molecular mechanisms of apoptosis

scientific article

A genetic pathway for the development of the Caenorhabditis elegans HSN motor neurons

scientific article published in December 1988

A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans.

scientific article published in March 1987

A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia

scientific article published on 18 January 2006

A neuronal acetylcholine receptor regulates the balance of muscle excitation and inhibition in Caenorhabditis elegans

scientific article

A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling

scientific article published in April 2004

A normally attractive cell interaction is repulsive in two C. elegans mesodermal cell migration mutants

scientific article published on November 1, 1991

A novel dominant transformer allele of the sex-determining gene her-1 of Caenorhabditis elegans

scientific article

A uniform genetic nomenclature for the nematode Caenorhabditis elegans

scientific article published on September 1, 1979

A visible allele of the muscle gene sup-10X of C. elegans

scientific article published on May 1986

Abl kinase inhibits the engulfment of apoptotic [corrected] cells in Caenorhabditis elegans

scientific article

Abnormal cell lineages in mutants of the nematode Caenorhabditis elegans

scientific article published in February 1981

Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2.

scientific article published on May 1994

Acyl-CoA Dehydrogenase Drives Heat Adaptation by Sequestering Fatty Acids

scientific article published on 14 May 2015

An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites

scientific article published on November 17, 1995

An Sp1 transcription factor coordinates caspase-dependent and -independent apoptotic pathways

scientific article published on 14 July 2013

An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor

scientific article published in July 1996

Axons degenerate in the absence of mitochondria in C. elegans

scientific article

Bacteriophage T4 mutants deficient in alteration and modification of the Escherichia coli RNA polymerase

scientific article published on 01 December 1974

Both the Caspase CSP-1 and a Caspase-Independent Pathway Promote Programmed Cell Death in Parallel to the Canonical Pathway for Apoptosis in Caenorhabditis elegans

scientific article published on March 7, 2013

Both the apoptotic suicide pathway and phagocytosis are required for a programmed cell death in Caenorhabditis elegans

scientific article

C. elegans CARMIL negatively regulates UNC-73/Trio function during neuronal development

scientific article

C. elegans HAM-1 positions the cleavage plane and regulates apoptosis in asymmetric neuroblast divisions.

scientific article published in August 2005

C. elegans ISWI and NURF301 antagonize an Rb-like pathway in the determination of multiple cell fates

scientific article published on 14 June 2006

C. elegans MCM-4 is a general DNA replication and checkpoint component with an epidermis-specific requirement for growth and viability

scientific article published on 10 December 2010

C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span

scientific article published in June 2006

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

scientific article

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

scientific article (publication date: 26 March 1992)

C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway

scientific article (publication date: June 2000)

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

scientific article published on April 2, 1998

C. elegans unc-105 mutations affect muscle and are suppressed by other mutations that affect muscle

scientific article

CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans

scientific article published in January 2001

CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

scientific article

CYSL-1 interacts with the O2-sensing hydroxylase EGL-9 to promote H2S-modulated hypoxia-induced behavioral plasticity in C. elegans

scientific article

Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor

scientific article published on November 20, 1997

Caenorhabditis elegans early embryogenesis and vulval morphogenesis require chondroitin biosynthesis

scientific article published in May 2003

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

scientific article published on April 9, 1992

Caenorhabditis elegans genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33

scientific article published on 05 May 2008

Caenorhabditis elegans mutants defective in the functioning of the motor neurons responsible for egg laying

scientific article

Caenorhabditis elegans rab-3Mutant Synapses Exhibit Impaired Function and Are Partially Depleted of Vesicles

scientific article published on November 1, 1997

Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction

scientific article published in Nature

Cell interactions control the direction of outgrowth, branching and fasciculation of the HSN axons of Caenorhabditis elegans

scientific article published on March 1993

Cell interactions coordinate the development of the C. elegans egg-laying system

scientific article

Chemosensory cell function in the behavior and development of Caenorhabditis elegans

scientific article published on January 1990

Chemosensory neurons with overlapping functions direct chemotaxis to multiple chemicals in C. elegans

scientific article published on November 1, 1991

Chimeric mutations in the M2 segment of the 5-hydroxytryptamine-gated chloride channel MOD-1 define a minimal determinant of anion/cation permeability

scientific article published on 4 May 2005

Chromosome-biased binding and gene regulation by the Caenorhabditis elegans DRM complex

scientific article (publication date: May 2011)

Chronic bleeding secondary to an unresectable duodenal adenocarcinoma controlled with sucralfate and famotidine

scientific article published on 01 May 1998

Control by bacteriophage T4 of two sequential phosphorylations of the alpha subunit of Escherichia coli RNA polymerase

scientific article published on December 25, 1974

Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39.

scientific article

Control of larval development by chemosensory neurons in Caenorhabditis elegans

scientific article published on 01 March 1991

Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein

scientific article published in December 1994

Coordinated transcriptional regulation of the unc-25 glutamic acid decarboxylase and the unc-47 GABA vesicular transporter by the Caenorhabditis elegans UNC-30 homeodomain protein

scientific article published on August 1999

Correction: Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans.

scientific article published on 11 June 2009

Cytochrome P450 drives a HIF-regulated behavioral response to reoxygenation by C. elegans

scientific article published on 27 June 2013

DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans

scientific article published on 21 January 2007

Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans

scientific article published in November 1995

Detection of mutations and DNA polymorphisms using whole genome Southern Cross hybridization

scientific article published on February 1990

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities

scientific article published on 01 March 1996

Dinucleotide repeat polymorphisms (D21S223 and D21S224) at 21q22.1

scientific article published on October 1, 1992

Distinct Neural Circuits Control Rhythm Inhibition and Spitting by the Myogenic Pharynx of C. elegans

scientific article

Dominant suppressors of a muscle mutant define an essential gene of Caenorhabditis elegans.

scientific article published on June 1982

Dopamine signaling is essential for precise rates of locomotion by C. elegans

scientific article

EAT-4, a homolog of a mammalian sodium-dependent inorganic phosphate cotransporter, is necessary for glutamatergic neurotransmission in caenorhabditis elegans

scientific article published on January 1999

EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins

scientific article

Effects of starvation and neuroactive drugs on feeding in Caenorhabditis elegans

scientific article published in March 1990

Egg-laying defective mutants of the nematode Caenorhabditis elegans

scientific article

Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis

scientific article

FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans

scientific article

Fate of the nuclear lamina during Caenorhabditis elegans apoptosis

scientific article published on 01 January 2002

Gain-of-Function Mutations in the Caenorhabditis elegans lin-1 ETS Gene Identify a C-Terminal Regulatory Domain Phosphorylated by ERK MAP Kinase

scientific article published on August 1, 1998

Gene linkage in familial amyotrophic lateral sclerosis: a progress report.

scientific article published in January 1991

Genes involved in two Caenorhabditis elegans cell-signaling pathways

scientific article published on January 1, 1992

Genes necessary for directed axonal elongation or fasciculation in C. elegans

scientific article published on February 1, 1992

Genes required for GABA function in Caenorhabditis elegans

scientific article published in July 1993

Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans

scientific article

Genetic Control of Programmed Cell Death in C. Elegans.

scientific article published on 17 August 2001

Genetic and physical mapping of the GLUR5 glutamate receptor gene on human chromosome 21

scientific article published on 01 November 1994

Genetic control of Caenorhabditis elegans cell lineage

scientific article published on January 1988

Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

scientific article published in February 1999

Genetic control of programmed cell death in the nematode C. elegans.

scientific article published in March 1986

Genetic control of programmed cell death in the nematode Caenorhabditis elegans.

scientific article

Genetic linkage analysis of familial amyotrophic lateral sclerosis using human chromosome 21 microsatellite DNA markers

scientific article published in May 1994

Genetics of programmed cell death in C. elegans: past, present and future.

scientific article

Genetics society of america program and abstracts.

scientific article published on June 1989

Gonadal cell lineages of the nematode Panagrellus redivivus and implications for evolution by the modification of cell lineage

scientific article published on 01 November 1981

Heterochronic mutants of the nematode Caenorhabditis elegans

scientific article published in October 1984

Hypoxia-inducible factor cell non-autonomously regulates stress responses and behavior via a nuclear receptor

article

IRK-1 potassium channels mediate peptidergic inhibition of Caenorhabditis elegans serotonin neurons via a G(o) signaling pathway

scientific article published on November 2012

Identification and characterization of 22 genes that affect the vulval cell lineages of the nematode Caenorhabditis elegans

scientific article

Identification and characterization of genes that interact with lin-12 in Caenorhabditis elegans

scientific article

Identification and classification of genes that act antagonistically to let-60 Ras signaling in Caenorhabditis elegans vulval development

scientific article

Identification of three novel mutations in the gene for Cu/Zn superoxide dismutase in patients with familial amyotrophic lateral sclerosis

scientific article published on September 1995

Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis

scientific article

Identification of two novel mutations and a new polymorphism in the gene for Cu/Zn superoxide dismutase in patients with amyotrophic lateral sclerosis

scientific article published in June 1994

In vivo effects on intron retention and exon skipping by the U2AF large subunit and SF1/BBP in the nematode Caenorhabditis elegans

scientific article published on 27 October 2011

Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein

scientific article published on September 21, 1995

Isolation and genetic characterization of cell-lineage mutants of the nematode Caenorhabditis elegans

scientific article published on October 1, 1980

LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans

scientific article published on January 2000

LIN-61, one of two Caenorhabditis elegans malignant-brain-tumor-repeat-containing proteins, acts with the DRM and NuRD-like protein complexes in vulval development but not in certain other biological processes

scientific article published on 3 April 2007

Ligand-gated chloride channels are receptors for biogenic amines in C. elegans

scientific article published on July 2009

Light and hydrogen peroxide inhibit C. elegans Feeding through gustatory receptor orthologs and pharyngeal neurons

scientific article published on 29 January 2015

Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22

scientific article published on 01 October 2000

MAB-10/NAB acts with LIN-29/EGR to regulate terminal differentiation and the transition from larva to adult in C. elegans

scientific article published on September 1, 2011

MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans

scientific article

Many families of C. elegans microRNAs are not essential for development or viability

scientific article

Mass spectrometric evidence for neuropeptide-amidating enzymes in Caenorhabditis elegans

scientific article published on 27 February 2018

Mechanisms and Functions of Cell Death

scientific article published on January 1, 1991

Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question

scientific article published on January 24, 1992

Members of the miRNA-200 family regulate olfactory neurogenesis

scientific journal article

MicroRNA expression in zebrafish embryonic development

scientific article

MicroRNA expression profiles classify human cancers

scientific article (publication date: 9 June 2005)

Microarray analysis of microRNA expression in the developing mammalian brain

scientific article published in 2004

Migrations of the Caenorhabditis elegans HSNs are regulated by egl-43, a gene encoding two zinc finger proteins

scientific article published in November 1993

Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14.

scientific article

Most Caenorhabditis elegans microRNAs are individually not essential for development or viability

scientific article

Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva

scientific article published in June 1991

Multiple levels of redundant processes inhibit Caenorhabditis elegans vulval cell fates

scientific article published on 9 August 2008

Mutational analysis of the Caenorhabditis elegans cell-death gene ced-3.

scientific article

Mutations in synaptojanin disrupt synaptic vesicle recycling

scientific article

Mutations in the Caenorhabditis elegans U2AF large subunit UAF-1 alter the choice of a 3' splice site in vivo

scientific article (publication date: November 2009)

Mutations in the Caenorhabditis elegans serotonin reuptake transporter MOD-5 reveal serotonin-dependent and -independent activities of fluoxetine.

scientific article

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

scientific article (publication date: 27 February 2009)

Mutations in the alpha1 subunit of an L-type voltage-activated Ca2+ channel cause myotonia in Caenorhabditis elegans

scientific article

Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis

scientific article published on May 1, 1998

Mutations that affect neural cell lineages and cell fates during the development of the nematode Caenorhabditis elegans

scientific article

Mutations that lead to reiterations in the cell lineages of C. elegans

scientific article published on April 1, 1981

Mutations that perturb vulval invagination in C. elegans

scientific article published on 01 January 1997

Mutations with dominant effects on the behavior and morphology of the nematode Caenorhabditis elegans

scientific article

NUC-1, a caenorhabditis elegans DNase II homolog, functions in an intermediate step of DNA degradation during apoptosis

scientific article

Nematode postembryonic cell lineages.

scientific article published on April 1982

Neurone differentiation in cell lineage mutants of Caenorhabditis elegans

scientific article published on 01 June 1982

New Genes That Interact With lin-35 Rb to Negatively Regulate the let-60 ras Pathway in Caenorhabditis elegans

scientific article published on May 1, 2003

No association ofDYNC1H1with sporadic ALS in a case‐control study of a northern European derived population: A tagging SNP approach

article

Nobel lecture. Worms, life and death

scientific article published in October 2003

Nondisjunction Mutants of the Nematode CAENORHABDITIS ELEGANS.

scientific article

Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-11.

scientific article published in April 1990

Obituary: Stanley J. Korsmeyer (1950-2005).

scientific article

Odorant-selective genes and neurons mediate olfaction in C. elegans.

scientific article published on August 1993

Otx-dependent expression of proneural bHLH genes establishes a neuronal bilateral asymmetry in C. elegans.

scientific article

PAG-3, a Zn-finger transcription factor, determines neuroblast fate in C. elegans.

scientific article published in April 2002

Pattern formation during vulval development in C. elegans

scientific article

Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3.

scientific article

Phagocytosis promotes programmed cell death in C. elegans

scientific article published in July 2001

Pharyngeal pumping continues after laser killing of the pharyngeal nervous system of C. elegans

scientific article published on October 1989

Phosphorylation of IκB-α Inhibits Its Cleavage by Caspase CPP32 in Vitro

scientific article published on November 21, 1997

Polypeptide Bound to the Host RNA Polymerase is Specified by T4 Control Gene 33

scientific article published on 01 August 1973

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

scientific article (publication date: March 1977)

Postembryonic nongonadal cell lineages of the nematode Panagrellus redivivus: description and comparison with those of Caenorhabditis elegans

scientific article published on 01 September 1982

Presumptive TRP channel CED-11 promotes cell volume decrease and facilitates degradation of apoptotic cells in Caenorhabditis elegans

scientific article published on 31 July 2017

Programmed cell death in Caenorhabditis elegans

article

Programmed elimination of cells by caspase-independent cell extrusion in C. elegans

scientific article published on August 9, 2012

Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans

scientific article

Receptors and Other Signaling Proteins Required for Serotonin Control of Locomotion inCaenorhabditis elegans

scientific article published on September 28, 2012

Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis

scientific journal article

Refined mapping and characterization of the recessive familial amyotrophic lateral sclerosis locus (ALS2) on chromosome 2q33

scientific article

Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50.

scientific article

Replication stress promotes cell elimination by extrusion

scientific article published on 05 May 2021

Replication-coupled chromatin assembly generates a neuronal bilateral asymmetry in C. elegans

scientific article published on 15 December 2011

SLI-1 Cbl Inhibits the Engulfment of Apoptotic Cells in C. elegans through a Ligase-Independent Function

scientific article published on December 13, 2012

SPK-1, an SR protein kinase, inhibits programmed cell death in Caenorhabditis elegans

scientific article

SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP-N- acetylgalactosamine, and UDP-galactose

scholarly article

Serotonin and octopamine in the nematode Caenorhabditis elegans

scientific article

Signal transduction during C. elegans vulval induction

scientific article published on November 1, 1991

Six and Eya promote apoptosis through direct transcriptional activation of the proapoptotic BH3-only gene egl-1 in Caenorhabditis elegans

scientific article

Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complex

scholarly article

Studies of mutations in T4 control genes 33 and 55

scientific article published on March 1, 1975

Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis

scientific article published on 01 May 1995

Tc4, a Caenorhabditis elegans transposable element with an unusual fold-back structure

scientific article published on April 15, 1991

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

scientific article (publication date: 24 February 2000)

The C. elegans MicroRNA mir-71 Acts in Neurons to Promote Germline-Mediated Longevity through Regulation of DAF-16/FOXO

scientific article published on April 4, 2012

The C. elegans PH Domain Protein CED-12 Regulates Cytoskeletal Reorganization via a Rho/Rac GTPase Signaling Pathway

scientific article (publication date: October 2001)

The C. elegans Protein EGL-1 Is Required for Programmed Cell Death and Interacts with the Bcl-2–like Protein CED-9

scientific article published on May 15, 1998

The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters.

scientific article published in June 1998

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

scientific article

The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein

scientific article

The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors

scientific article

The C. elegans gene lin-36 acts cell autonomously in the lin-35 Rb pathway

scientific article published in August 1999

The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously

scientific article published in October 1995

The C. elegans gene lin-9,which acts in an Rb-related pathway, is required for gonadal sheath cell development and encodes a novel protein

scientific article published in August 2000

The C. elegans protein CEH-30 protects male-specific neurons from apoptosis independently of the Bcl-2 homolog CED-9.

scientific article

The CDK8 Complex and Proneural Proteins Together Drive Neurogenesis from a Mesodermal Lineage

scientific article published on 18 February 2017

The Caenorhabditis elegans F-box protein SEL-10 promotes female development and may target FEM-1 and FEM-3 for degradation by the proteasome

scholarly article

The Caenorhabditis elegans LIN-26 protein is required to specify and/or maintain all non-neuronal ectodermal cell fates.

scientific article published in September 1996

The Caenorhabditis elegans behavioral gene unc-24 encodes a novel bipartite protein similar to both erythrocyte band 7.2 (stomatin) and nonspecific lipid transfer protein.

scientific article published in July 1996

The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death

scientific article published on October 1, 1992

The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease

scientific article published in May 1996

The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway

scientific article published in December 1995

The Caenorhabditis elegans gene lin-10 is broadly expressed while required specifically for the determination of vulval cell fates

scientific article published in March 1990

The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein

scientific article published in September 1996

The Caenorhabditis elegans gene lin-26 is required to specify the fates of hypodermal cells and encodes a presumptive zinc-finger transcription factor

scientific article published in September 1994

The Caenorhabditis elegans gene lin-44 controls the polarity of asymmetric cell divisions

scientific article published in May 1994

The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK

scientific article published on 01 March 1995

The Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicing

scientific article

The Caenorhabditis elegans gene sem-4 controls neuronal and mesodermal cell development and encodes a zinc finger protein

scientific article published in August 1996

The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development.

scientific article published on January 1999

The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation

scientific article

The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death

scientific article

The Caenorhabditis elegans genes sqv-2 and sqv-6, which are required for vulval morphogenesis, encode glycosaminoglycan galactosyltransferase II and xylosyltransferase

scientific article published on 12 February 2003

The Caenorhabditis elegans iodotyrosine deiodinase ortholog SUP-18 functions through a conserved channel SC-box to regulate the muscle two-pore domain potassium channel SUP-9.

scientific article

The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins

scientific article

The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types

scientific article

The Caenorhabditis elegans synthetic multivulva genes prevent ras pathway activation by tightly repressing global ectopic expression of lin-3 EGF

scientific article

The Caenorhabditis elegans unc-31 gene affects multiple nervous system-controlled functions.

scientific article

The Caenorhabditis elegans unc-93 gene encodes a putative transmembrane protein that regulates muscle contraction.

scientific article

The Caenorhabditis elegans vulval morphogenesis gene sqv-4 encodes a UDP-glucose dehydrogenase that is temporally and spatially regulated

scientific article

The Conserved VPS-50 Protein Functions in Dense-Core Vesicle Maturation and Acidification and Controls Animal Behavior

scientific article published on 2 March 2016

The GABAergic nervous system of Caenorhabditis elegans

scientific article published on July 1993

The LIM region of a presumptive Caenorhabditis elegans transcription factor is an iron-sulfur- and zinc-containing metallodomain

scientific article published on October 1991

The LIN-15A and LIN-56 transcriptional regulators interact to negatively regulate EGF/Ras signaling in Caenorhabditis elegans vulval cell-fate determination

scientific article

The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development

scientific article

The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene

scientific article

The ced-8 gene controls the timing of programmed cell deaths in C. elegans.

scientific article published in March 2000

The combined action of two intercellular signaling pathways specifies three cell fates during vulval induction in C. elegans

scientific article published in August 1989

The engulfment process of programmed cell death in caenorhabditis elegans

scientific article published in January 2004

The genetic control of cell lineage during nematode development

scientific article published on January 1984

The genetics of programmed cell death in the nematode Caenorhabditis elegans.

scientific article

The ins and outs of programmed cell death during C. elegans development

scientific article published on August 1994

The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

scientific journal article

The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans

scientific article

The lin-11 LIM domain transcription factor is necessary for morphogenesis of C. elegans uterine cells

scientific article published on December 1999

The lin-12 locus specifies cell fates in Caenorhabditis elegans

scientific article

The lin-14 locus of Caenorhabditis elegans controls the time of expression of specific postembryonic developmental events

scientific article

The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor

scientific article (publication date: April 2000)

The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways.

scientific article published on September 1989

The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans

scientific article

The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone

scientific journal article

The translational regulators GCN-1 and ABCF-3 act together to promote apoptosis in C. elegans

scientific article

Three new classes of mutations in the Caenorhabditis elegans muscle gene sup-9.

scientific article published on September 1993

Three novel mutations and two variants in the gene for Cu/Zn superoxide dismutase in familial amyotrophic lateral sclerosis.

scientific article published in October 1996

Three proteins involved in Caenorhabditis elegans vulval invagination are similar to components of a glycosylation pathway

scientific article

ThreeC. elegansRac proteins and several alternative Rac regulators control axon guidance, cell migration and apoptotic cell phagocytosis

scientific article published on November 1, 2001

Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2.

scientific article

Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death

scientific article

Two C. elegans genes control the programmed deaths of specific cells in the pharynx

scientific article published on June 1, 1991

Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development

scientific article published on 18 July 2007

Two independent dinucleotide repeat polymorphisms at the D21S235 locus (21q22.1)

scientific article published on November 1, 1992

Tyramine Functions independently of octopamine in the Caenorhabditis elegans nervous system

scientific article

UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development

scientific article

US immigration order strikes against biotech.

scientific article

Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration

scientific article

Wnt and EGF pathways act together to induce C. elegans male hook development

scientific article published on 30 December 2008

Worms, life, and death (Nobel lecture).

scientific article published in August 2003

Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells

scientific article

clr-1 encodes a receptor tyrosine phosphatase that negatively regulates an FGF receptor signaling pathway in Caenorhabditis elegans

scientific article published on May 15, 1998

dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development

scientific article published in March 2001

lin-17 mutations of Caenorhabditis elegans disrupt certain asymmetric cell divisions.

scientific article published in November 1988

lin-35 and lin-53, two genes that antagonize a C. elegans Ras pathway, encode proteins similar to Rb and its binding protein RbAp48.

scientific article published on December 1998

lin-8, which antagonizes Caenorhabditis elegans Ras-mediated vulval induction, encodes a novel nuclear protein that interacts with the LIN-35 Rb protein

scientific article

sqv mutants of Caenorhabditis elegans are defective in vulval epithelial invagination

scientific article

unc-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration

scientific article published in December 2001

unc-93(e1500): A behavioral mutant of Caenorhabditis elegans that defines a gene with a wild-type null phenotype

scientific article