List of works by Jeffrey I. Weitz

'Realworld' use of non-vitamin K antagonist oral anticoagulants (NOACs): Lessons from the Dresden NOAC Registry

scientific article published on 16 April 2015

2017 Scientific Sessions Sol Sherry Distinguished Lecture in Thrombosis: Factor XI as a Target for New Anticoagulants

scientific article published on 21 December 2017

A PoTENtial Antidote: A Prohemostatic Factor Xa Variant for Reversal of Direct Oral Anticoagulants

scientific article published on 01 November 2016

A Replacement for Warfarin

A Risk Assessment Tool Incorporating New Biomarkers for Cardiovascular Events in Acute Coronary Syndromes: The Organization to Assess Strategies in Ischemic Syndromes (OASIS) Risk Score

scientific article published on 2 February 2016

A Test in Context: D-Dimer

scientific article published in November 2017

A diagnostic strategy involving a quantitative latex D-dimer assay reliably excludes deep venous thrombosis

scientific article

A dose-finding study with TAK-442, an oral factor Xa inhibitor, in patients undergoing elective total knee replacement surgery ⬇️

scientific article published on September 30, 2010

A high affinity interaction of plasminogen with fibrin is not essential for efficient activation by tissue-type plasminogen activator

scientific article published on 20 December 2011

A non-anticoagulant synthetic pentasaccharide reduces inflammation in a murine model of kidney ischemia-reperfusion injury

scientific article published on 01 December 2006

A novel approach to thrombin inhibition

scientific article

A randomised, double blind comparison of tecarfarin, a novel vitamin K antagonist, with warfarin. The EmbraceAC Trial.

scientific article published on 12 May 2016

AB023, A Novel Antibody That Binds Factor XI and Blocks Its Activation by Factor XIIa

scientific article published on 01 April 2019

Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) attenuates fibrin-dependent plasmin generation on thrombin-activated platelets

scientific article published on 07 June 2020

Acute coronary syndromes: a focus on thrombin

scientific article (publication date: April 2002)

Advances in Antithrombotic Therapy

scientific article published on 01 January 2019

Advances in Therapy and the Management of Antithrombotic Drugs for Venous Thromboembolism

scientific article

Advances in Thrombosis and Hemostasis: An Introduction to the Compendium

scientific article published on 01 April 2016

An evaluation of D-dimer in the diagnosis of pulmonary embolism: a randomized trial

scientific article published in June 2006

An omniphobic lubricant-infused coating produced by chemical vapor deposition of hydrophobic organosilanes attenuates clotting on catheter surfaces

scientific article published on 14 September 2017

An open-label study of the pharmacokinetics and pharmacodynamics of dabigatran etexilate 150mg once daily in Caucasian patients with moderate renal impairment undergoing primary unilateral elective total knee or hip replacement surgery

scientific article published on 16 June 2016

An update on new anticoagulants

scientific article published on December 2003

Another oral thrombin inhibitor for stroke prevention in atrial fibrillation?

Antibody-Based Ticagrelor Reversal Agent in Healthy Volunteers

scientific article published on 17 March 2019

Antibody-Based Ticagrelor Reversal Agent in Healthy Volunteers. Reply

scientific article published on 01 August 2019

Anticoagulant-Associated Intracranial Hemorrhage in the Era of Reversal Agents

scientific article published on 11 April 2017

Anticoagulants in heart disease: current status and perspectives

scientific article published on 10 April 2007

Anticoagulation for Mechanical Heart Valves: Will Oral Factor Xa Inhibitors Be Effective?

scientific article

Anticoagulation for ST-Segment Elevation Myocardial Infarction

Anticoagulation therapy in 2015: where we are and where we are going

scientific article

Anticoagulation therapy patterns for acute treatment of venous thromboembolism in GARFIELD-VTE patients

scientific article published on 23 July 2019

Anticoagulation therapy. Dabigatran and risk of myocardial infarction

scientific article published on 13 March 2012

Antiphospholipid Antibodies and Recurrent Thrombosis after a First Unprovoked Venous Thromboembolism.

scientific article published on 28 February 2018

Antiplatelet drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

scientific article published on February 2012

Antiplatelet therapy in the management of atherothrombosis: recent clinical advances

scientific article published on 01 July 2018

Antithrombin-heparin covalent complex: a possible alternative to heparin for arterial thrombosis prevention

scientific article published on 01 July 2002

Antithrombin-independent anticoagulation by hypersulfated low-molecular-weight heparin

scientific article

Antithrombotic Activity of the Novel Oral Anticoagulant, Tecarfarin [Sodium 3-[4-((1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yloxy) carbonyl) benzyl]-2-oxo-2H-chromen-4-olate] in Animal Models ⬇️

scientific article published on November 1, 2010

Antithrombotic Agents

scientific article published on 01 February 2019

Antithrombotic therapy during percutaneous coronary intervention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

scientific article (publication date: September 2004)

Apixaban for extended treatment of venous thromboembolism

scientific article published on 08 December 2012

Apixaban versus enoxaparin for thromboprophylaxis in medically ill patients

scientific article

Appropriate Apixaban Dosing: Prescribers Take Note.

scientific article

Are Ticks the Answer to Medical Device-Associated Clotting?

scientific article published on 01 October 2019

Arterial thrombosis is accelerated in mice deficient in histidine-rich glycoprotein

scientific article published on 17 February 2015

Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events

scientific article (publication date: 9 April 2002)

Assays for Measuring Rivaroxaban: Their Suitability and Limitations ⬇️

scientific article published on December 1, 2010

Assessment of Outcomes Among Patients With Venous Thromboembolism With and Without Chronic Kidney Disease

scientific article published on 01 October 2020

Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in patients with non-valvular atrial fibrillation

scientific article published on 23 April 2020

Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in the prevention of venous thromboembolism

scientific article published on 23 April 2020

Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in the treatment of venous thromboembolism

scientific article published on 23 April 2020

Batroxobin binds fibrin with higher affinity and promotes clot expansion to a greater extent than thrombin

scientific article published on 23 April 2013

Benefits and risks of extended treatment of venous thromboembolism with rivaroxaban or with aspirin

scientific article published on 10 July 2018

Beyond heparin and warfarin: the new generation of anticoagulants

scientific article

Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores

scientific article

Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores

scientific article published on 01 November 2015

Bivalent binding to gammaA/gamma'-fibrin engages both exosites of thrombin and protects it from inhibition by the antithrombin-heparin complex

scientific article published on 30 November 2007

Bivalirudin, thrombin and platelets: clinical implications and future directions

scientific article published on August 2003

By increasing the affinity of heparin for fibrin, Zn(2+) promotes the formation of a ternary heparin-thrombin-fibrin complex that protects thrombin from inhibition by antithrombin

scientific article published on 28 September 2012

COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up

scientific article published on 15 April 2020

COVID-19 coagulopathy, thrombosis, and bleeding

scientific article published on 01 July 2020

Cancer associated thrombosis in everyday practice: perspectives from GARFIELD-VTE

scientific article published on 24 June 2020

Catheter thrombosis and percutaneous coronary intervention: fundamental perspectives on blood, artificial surfaces and antithrombotic drugs

scientific article published on October 2009

Cell-Free DNA Modulates Clot Structure and Impairs Fibrinolysis in Sepsis

scientific article published on 22 October 2015

Changing paradigms in the management of venous thromboembolism

scientific article

Characteristics and Management of Patients with Venous Thromboembolism: The GARFIELD-VTE Registry

scientific article published on 28 December 2018

Characteristics and Outcomes in Patients with Venous Thromboembolism Taking Concomitant Anti-Platelet Agents and Anticoagulants in the AMPLIFY Trial

scientific article published on 16 January 2019

Characterization of Patients with Embolic Strokes of Undetermined Source in the NAVIGATE ESUS Randomized Trial.

scientific article published on 7 March 2018

Choosing wisely: The impact of patient selection on efficacy and safety outcomes in the EINSTEIN-DVT/PE and AMPLIFY trials

scientific article published on 21 November 2016

Ciraparantag for enoxaparin reversal: Adding to the evidence.

scientific article

Clinical Impact of Bleeding in Cancer-Associated Venous Thromboembolism: Results from the Hokusai VTE Cancer Study

scientific article published on 30 July 2018

Clinical implications of incidental venous thromboembolism in cancer patients

scientific article published on 06 February 2020

Clinical presentation and course of bleeding events in patients with venous thromboembolism, treated with apixaban or enoxaparin and warfarin. Results from the AMPLIFY trial

scientific article published on 01 September 2016

Coagulation assays

scientific article published in July 2005

Combination Antiplatelet and Oral Anticoagulant Therapy in Patients With Coronary and Peripheral Artery Disease

scientific article published on 01 April 2019

Comment on model-based meta-analysis to evaluate optimal doses of direct oral factor Xa inhibitors in atrial fibrillation patients

scholarly article published 27 November 2018

Comparative effectiveness of oral anticoagulants in venous thromboembolism: GARFIELD-VTE

scientific article published on 28 April 2020

Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development

scientific article

Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism

scientific article published in August 2003

Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials

scientific article published on 4 December 2013

Contribution of host-derived tissue factor to tumor neovascularization

scientific article

Corn trypsin inhibitor coating attenuates the prothrombotic properties of catheters in vitro and in vivo

scientific article published on 21 July 2012

Dabigatran Reversal With Idarucizumab in Patients Requiring Urgent Surgery: A Subanalysis of the RE-VERSE AD Study

scientific article published on 09 October 2019

Dabigatran Reversal With Idarucizumab in Patients With Renal Impairment

scientific article published on 01 October 2019

Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function

scientific article

Dabigatran attenuates thrombin generation to a lesser extent than warfarin: could this explain their differential effects on intracranial hemorrhage and myocardial infarction?

scientific article published in February 2013

Dabigatran etexilate for prevention of venous thromboembolism

scientific article published on 01 January 2009

Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve-Induced Thrombin Generation

scientific article published on 24 August 2015

Dabigatran-related coagulopathy: when can we assume the effect has "worn off"?

scientific article published on 29 August 2014

Delayed but not Early Treatment with DNase Reduces Organ Damage and Improves Outcome in a Murine Model of Sepsis

scientific article published on August 2015

Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatran

scientific article published on 28 May 2015

Direct Oral Anticoagulants for Pulmonary Embolism: Importance of Anatomical Extent

scientific article published on 08 January 2018

Direct oral anticoagulants for cancer-associated venous thromboembolism: a systematic review and meta-analysis

scientific article published on 12 May 2020

Direct thrombin inhibitors

scientific article published on 01 May 2002

Direct thrombin inhibitors in acute coronary syndromes: present and future

scientific article

Direct thrombin inhibitors in cardiac disease

scientific article (publication date: 2003)

Dose reduction of edoxaban preserves efficacy and safety for the treatment of venous thromboembolism. An analysis of the randomised, double-blind HOKUSAI VTE trial

scientific article published on 21 July 2016

Dual surface modification with PEG and corn trypsin inhibitor: effect of PEG:CTI ratio on protein resistance and anticoagulant properties

scientific article published on 12 January 2012

Dual-pathway inhibition for secondary and tertiary antithrombotic prevention in cardiovascular disease

scientific article published on 17 January 2020

Early time courses of recurrent thromboembolism and bleeding during apixaban or enoxaparin/warfarin therapy. A sub-analysis of the AMPLIFY trial

scientific article published on 10 December 2015

Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism

scientific article

Edoxaban for treatment of venous thromboembolism in patients with cancer. Rationale and design of the Hokusai VTE-cancer study.

scientific article

Edoxaban for venous thromboembolism in patients with cancer: results from a non-inferiority subgroup analysis of the Hokusai-VTE randomised, double-blind, double-dummy trial.

scientific article published on July 2016

Effect of Different Doses of Acetylsalicylic Acid on the Antithrombotic Activity of Clopidogrel in a Mouse Arterial Thrombosis Model

scientific article published on 01 October 2018

Effect of Osocimab in Preventing Venous Thromboembolism Among Patients Undergoing Knee Arthroplasty: The FOXTROT Randomized Clinical Trial

scientific article published on 01 January 2020

Effect of recombinant factor VIIa on melagatran-induced inhibition of thrombin generation and platelet activation in healthy volunteers

scientific article published on 01 June 2004

Emerging anticoagulant drugs

scientific article

Emerging anticoagulant strategies

scientific article

Emerging anticoagulants for the treatment of venous thromboembolism

scientific article published on 01 September 2006

Emerging themes in the treatment of venous thromboembolism

scientific article published on 01 September 2006

Emerging therapies for stroke prevention in atrial fibrillation

scientific article published in May 2005

Establishing Therapeutic Equivalence of Complex Pharmaceuticals: The Case of Dabigatran

scientific article published on 05 June 2018

Evaluation of DNA aptamers directed to thrombin as potential thrombus imaging agents

scientific article

Evaluation of direct oral anticoagulants in superficial-vein thrombosis - Authors' reply.

scientific article

Evidence that both exosites on thrombin participate in its high affinity interaction with fibrin

scientific article published on 7 April 2003

Evolving Treatments for Arterial and Venous Thrombosis: Role of the Direct Oral Anticoagulants

scientific article published on April 2016

Evolving use of new oral anticoagulants for treatment of venous thromboembolism

scientific article

Exosite 2-Directed Ligands Attenuate Protein C Activation by the Thrombin-Thrombomodulin Complex.

scientific article published on 26 May 2017

Expanding use of new oral anticoagulants

scientific article

Expert Consensus Guidelines for Stocking of Antidotes in Hospitals That Provide Emergency Care.

scientific article published on 29 June 2017

Extended anticoagulant therapy in venous thromboembolism: a balanced, fractional factorial, clinical vignette-based study

scientific article published on 07 March 2019

Extended duration of anticoagulation with edoxaban in patients with venous thromboembolism: a post-hoc analysis of the Hokusai-VTE study

scientific article

Extended treatment of venous thromboembolism

scientific article published in May 2013

Extended treatment with edoxaban in cancer patients with venous thromboembolism: A post-hoc analysis of the Hokusai-VTE Cancer study

scientific article published on 25 July 2019

Factor XI and factor XII as targets for new anticoagulants

scientific article

Factor XI antisense oligonucleotide for prevention of venous thrombosis

scientific article

Factor XI antisense oligonucleotide for venous thrombosis

scientific article published on 01 April 2015

Factor XIII Prevents Pulmonary Emboli in Mice by Stabilizing Deep Vein Thrombi

scientific article published on 20 April 2019

Factor Xa and thrombin as targets for new oral anticoagulants

scientific article published on 01 January 2011

Factors XI and XII as Targets for New Anticoagulants

scientific article published on 24 February 2017

Four-factor prothrombin complex concentrate for urgent reversal of vitamin K antagonists in patients with major bleeding

scientific article

G-protein-coupled receptors as signaling targets for antiplatelet therapy

scientific article

Gastrointestinal Bleeding With Edoxaban Versus Warfarin: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis In Myocardial Infarction)

scientific article published on 01 May 2018

Gastrointestinal bleeding with the new oral anticoagulants--defining the issues and the management strategies

scientific article published on 23 May 2013

General mechanisms of coagulation and targets of anticoagulants (Section I). Position Paper of the ESC Working Group on Thrombosis--Task Force on Anticoagulants in Heart Disease.

scientific article published on 28 February 2013

Genetics of coagulation: what the cardiologist needs to know

scientific article published on January 2013

Global Anticoagulant Registry in the Field - Venous Thromboembolism (GARFIELD-VTE). Rationale and design

scientific article published on 22 September 2016

Global public awareness about atrial fibrillation

scientific article published on 25 October 2017

Glycosaminoglycans Bind Factor Xa in a Ca2+-Dependent Fashion and Modulate Its Catalytic Activity ⬇️

scientific article published on November 11, 2003

Guided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group

scientific article

HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions

scientific article published on 15 September 2009

HD1, a thrombin-directed aptamer, binds exosite 1 on prothrombin with high affinity and inhibits its activation by prothrombinase

scientific article published on 17 October 2006

HD1, a thrombin-directed aptamer, binds exosite 1 on prothrombin with high affinity and inhibits its activation by prothrombinase

scientific article published in February 2015

Healthcare resource utilization in patients receiving idarucizumab for reversal of dabigatran anticoagulation due to major bleeding, urgent surgery, or procedural interventions: interim results from the RE-VERSE AD™ study

scientific article published on 16 December 2016

Heparan sulfate: antithrombotic or not?

scientific article

Heparin and angiogenesis: size matters!

scientific article

Heparin synergistically enhances interleukin-11 signaling through up-regulation of the MAPK pathway

scientific article published on 23 May 2006

Histidine-rich glycoprotein binds DNA and RNA and attenuates their capacity to activate the intrinsic coagulation pathway

scientific article published on 10 September 2015

Histidine-rich glycoprotein binds factor XIIa with high affinity and inhibits contact-initiated coagulation

scientific article

Histidine-rich glycoprotein binds fibrin(ogen) with high affinity and competes with thrombin for binding to the gamma'-chain

scientific article published on 08 July 2011

Hospitalized COVID-19 Patients and Venous Thromboembolism: A Perfect Storm

scientific article published on 13 July 2020

Hypercoagulability and COVID-19 associated hypoxemic respiratory failure: Mechanisms and emerging management paradigms

scientific article published on 01 September 2020

Hypercoagulable states

scientific article

Hypercoagulable states

scientific article published on 01 October 2011

Idarucizumab for Dabigatran Reversal

scientific article

Idarucizumab for Dabigatran Reversal - Full Cohort Analysis

scientific article published on 11 July 2017

Idarucizumab for dabigatran overdose.

scientific article

Idarucizumab: The Antidote for Reversal of Dabigatran

scientific article

Identification and characterization of a factor Va-binding site on human prothrombin fragment 2

scientific article published on 21 February 2019

Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion

scientific journal article

Idrabiotaparinux treatment for venous thromboembolism

scientific article published in The Lancet

Impact of age, comorbidity, and polypharmacy on the efficacy and safety of edoxaban for the treatment of venous thromboembolism: An analysis of the randomized, double-blind Hokusai-VTE trial

scientific article published on 13 December 2017

Impact of concomitant antiplatelet therapy on the efficacy and safety of DOACs for acute venous thromboembolism: systematic review and meta-analysis

scientific article published on 22 March 2020

Importance of family history as a risk factor for venous thromboembolism.

scientific article

In high-risk patients with arthritis and previous upper GI bleeding, celecoxib vs naproxen reduced recurrent bleeding.

scientific article

In the presence of phospholipids, glycosaminoglycans potentiate factor Xa-mediated protein C activation by modulating factor Xa activity

scientific article published on 08 March 2007

In vitro comparison of the effect of heparin, enoxaparin and fondaparinux on tests of coagulation

scientific article published in September 2002

Incident Atrial Fibrillation, Dementia and the Role of Anticoagulation: A Population-Based Cohort Study

scientific article published on 27 March 2019

Incorporating edoxaban into the choice of anticoagulants for atrial fibrillation

scientific article published on 15 October 2015

Incorporation of fragment X into fibrin clots renders them more susceptible to lysis by plasmin

scientific article published on 01 April 2006

Incorporation of vitronectin into fibrin clots. Evidence for a binding interaction between vitronectin and gamma A/gamma' fibrinogen.

scientific article published on 14 December 2001

Inferior vena cava ligation rapidly induces tissue factor expression and venous thrombosis in rats

scientific article published on 5 March 2009

Influence of model-predicted rivaroxaban exposure and patient characteristics on efficacy and safety outcomes in patients with acute coronary syndrome

scientific article published on 01 January 2019

Influence of thrombophilia on risk of recurrent venous thromboembolism while on warfarin: results from a randomized trial

scientific article

Inhibition of osteolytic bone metastasis by unfractionated heparin

scientific article published on 24 September 2008

Initial treatment of venous thromboembolism

scientific article published on 01 September 2006

Insights into the role of thrombin in the pathogenesis of recurrent ischaemia after acute coronary syndrome

scientific article published on 17 July 2014

Isolated Distal Deep Vein Thrombosis: Perspectives from the GARFIELD-VTE Registry

scientific article published on 01 August 2019

Laboratory Monitoring of Non-Vitamin K Antagonist Oral Anticoagulant Use in Patients With Atrial Fibrillation: A Review

scientific article published on 29 March 2017

Letter to the Editor: Managing Dabigatran-Related Bleeding

scientific article published on 01 January 2016

Leukocyte urokinase plasminogen activator receptor and PSGL1 play a role in endogenous arterial fibrinolysis

scientific article published in December 2009

Life-threatening thrombosis in mice with targeted Arg48-to-Cys mutation of the heparin-binding domain of antithrombin.

scientific article published on 30 October 2003

Linking Endogenous Factor Xa Activity, a Biologically Relevant Pharmacodynamic Marker, to Edoxaban Plasma Concentrations and Clinical Outcomes in the ENGAGE AF-TIMI 48 Trial

scientific article published on 01 October 2018

Localization of heparin and low-molecular-weight heparin in the rat kidney

scientific article published on 01 May 2004

Long range communication between exosites 1 and 2 modulates thrombin function

scientific article published on 9 July 2009

Long range communication between exosites 1 and 2 modulates thrombin function.

scientific article published in February 2015

Long term risk of symptomatic recurrent venous thromboembolism after discontinuation of anticoagulant treatment for first unprovoked venous thromboembolism event: systematic review and meta-analysis

scientific article published on 24 July 2019

Long-Term Management of Venous Thromboembolism: Lessons from EINSTEIN CHOICE and Other Extension Trials

scientific article published on 26 February 2019

Low-dose warfarin in rehabilitating stroke survivors

scientific article

Lubricant-Infused PET Grafts with Built-In Biofunctional Nanoprobes Attenuate Thrombin Generation and Promote Targeted Binding of Cells

scientific article published on 27 November 2019

Lubricant-Infused Surfaces with Built-In Functional Biomolecules Exhibit Simultaneous Repellency and Tunable Cell Adhesion

scientific article published on 24 October 2018

Lys 42/43/44 and Arg 12 of thrombin-activable fibrinolysis inhibitor comprise a thrombomodulin exosite essential for its antifibrinolytic potential.

scientific article published on 22 June 2017

MAA868 locks factor XIa in a zymogen-like state

scientific article published on 01 March 2019

Management of venous thromboembolism: present and future

scientific article

Markers of inflammation and activation of coagulation are associated with anaemia in antiretroviral-treated HIV disease

scientific article published in July 2014

Measuring Dabigatran Levels: What Tests Are Available and What Still Needs to Be Done?

scientific article published on 6 December 2017

Mechanism of catalysis of inhibition of factor IXa by antithrombin in the presence of heparin or pentasaccharide

scientific article

Mechanism of catheter thrombosis: comparison of the antithrombotic activities of fondaparinux, enoxaparin, and heparin in vitro and in vivo

scientific article published on 21 September 2011

Mechanisms Responsible for Catalysis of the Inhibition of Factor Xa or Thrombin by Antithrombin Using a Covalent Antithrombin-Heparin Complex ⬇️

scientific article published on April 14, 2003

Mechanistic Basis for the Differential Effects of Rivaroxaban and Apixaban on Global Tests of Coagulation

scientific article published on 01 April 2018

Meeting the unmet needs in anticoagulant therapy

scientific article published in July 2010

Modes and consequences of thrombin's interaction with fibrin

scientific article

Modification of polyurethane with polyethylene glycol-corn trypsin inhibitor for inhibition of factor Xlla in blood contact

scientific article published on 08 May 2012

More on Acutely Injured Patients Receiving Dabigatran

scientific article published on 01 March 2012

Mortality Risk Profiles for Sepsis: A Novel Longitudinal and Multivariable Approach

scientific article published on 01 August 2019

Multimerin 1 binds factor V and activated factor V with high affinity and inhibits thrombin generation

scientific article published in December 2008

NOAC monitoring, reversal agents, and post-approval safety and effectiveness evaluation: A cardiac safety research consortium think tank

scientific article published on 23 April 2016

Neutrophil extracellular traps promote thrombin generation through platelet-dependent and platelet-independent mechanisms

scientific article published on 10 July 2014

New Anticoagulants

scientific article published on 01 April 2010

New Anticoagulants: Moving Beyond the Direct Oral Anticoagulants

scientific article published on 12 October 2020

New and Emerging Anticoagulant Therapies for Venous Thromboembolism ⬇️

scientific article published on April 1, 2010

New anticoagulant drugs: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

scientific article published in September 2004

New anticoagulant therapy

scientific article

New anticoagulants

scientific article published on 10 June 2004

New anticoagulants

scientific article published on 01 December 2003

New anticoagulants for treatment of venous thromboembolism

scientific article

New anticoagulants for treatment of venous thromboembolism.

scientific article

New anticoagulants: an update.

scientific article

New anticoagulants: beyond heparin, low-molecular-weight heparin and warfarin

scientific article

New anticoagulants: current status and future potential

scientific article published on January 2003

New antithrombotic drugs: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)

scientific article published on 01 June 2008

New antithrombotic drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

scientific article published on February 2012

New developments in anticoagulants: Past, present and future

scientific article

New oral anticoagulants in atrial fibrillation and acute coronary syndromes: ESC Working Group on Thrombosis-Task Force on Anticoagulants in Heart Disease position paper

scientific article

New oral anticoagulants in development

scientific article published on 26 October 2009

New oral anticoagulants: a view from the laboratory

scientific article published on 09 March 2012

New oral anticoagulants: which one should my patient use?

scientific article published on January 2012

Non-vitamin K antagonist oral anticoagulants (NOACs): No longer new or novel

scientific article published on 21 March 2014

Non-vitamin K antagonist oral anticoagulants in atrial fibrillation patients with bioprosthetic valves

scientific article published on 23 May 2018

Non-vitamin K antagonist oral anticoagulants: an appeal for consensus on terminology

scientific article published on 01 May 2014

North American Thrombosis Forum, AF Action Initiative Consensus Document

scientific article published on May 2016

Novel antithrombotic strategies for treatment of venous thromboembolism

scientific article published on 01 January 2020

Novel antithrombotic therapies for the prevention of stroke in patients with atrial fibrillation

scientific article (publication date: April 2004)

Novel oral anticoagulants and reversal agents: Considerations for clinical development

scientific article published on 26 March 2015

Novel oral anticoagulants in gastroenterology practice

scientific article published on 29 May 2013

OASIS-6: should patients with acute ST-segment elevation myocardial infarction be treated with fondaparinux?

scientific article published on 01 September 2006

Obituary for Dr. Clive Kearon

scientific article published on 04 August 2020

Oncogenes as regulators of tissue factor expression in cancer: implications for tumor angiogenesis and anti-cancer therapy

scientific article (publication date: February 2004)

Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis

scientific article

Optimizing the safety of treatment for venous thromboembolism in the era of direct oral anticoagulants.

scientific article

Oral anticoagulants in coronary heart disease (Section IV). Position paper of the ESC Working Group on Thrombosis - Task Force on Anticoagulants in Heart Disease

scientific article published on 8 March 2016

Oral apixaban for the treatment of acute venous thromboembolism

scientific article published in July 2013

Oral direct factor Xa inhibition with edoxaban for thromboprophylaxis after elective total hip replacement. A randomised double-blind dose-response study

scientific article published on 29 June 2010

Oral direct factor Xa inhibitors

scientific article published on September 2012

Orally active direct thrombin inhibitors

scientific article published on May 2003

Otamixaban in acute coronary syndromes

scientific article published on 28 August 2009

Outpatient Management in Patients with Venous Thromboembolism with Edoxaban: A Post Hoc Analysis of the Hokusai-VTE Study.

scientific article published on 6 December 2017

Overview of Therapeutic Approaches for Cholesterol Lowering and Attenuation of Thrombosis for Prevention of Atherothrombosis

scientific article published on 01 February 2019

Overview of the new oral anticoagulants: opportunities and challenges

scientific article published on 19 March 2015

Parenteral anticoagulants: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

scientific article

Parenteral anticoagulants: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

scientific article

Patients with severe sepsis vary markedly in their ability to generate activated protein C

scientific article published on 19 August 2004

Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial

scientific article published on 03 May 2018

Periprocedural Management and Approach to Bleeding in Patients Taking Dabigatran

article

Periprocedural management of new oral anticoagulants in patients undergoing atrial fibrillation ablation

scientific article published on April 2014

Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research

scientific article published on 30 May 2020

Pharmacology and clinical potential of direct thrombin inhibitors

scientific article

Phase 2 study of TAK-442, an oral factor Xa inhibitor, in patients following acute coronary syndrome.

scientific article published on 27 March 2014

Plasma fibronectin supports hemostasis and regulates thrombosis

scientific article

Platelet polyphosphate: the long and the short of it.

scientific article

Post-Discharge Prophylaxis With Rivaroxaban Reduces Fatal and Major Thromboembolic Events in Medically Ill Patients

scientific article published on 01 June 2020

Potential of new anticoagulants in patients with cancer

scientific article published on April 2010

Practical management of bleeding in patients receiving non-vitamin K antagonist oral anticoagulants

scientific article published on 09 July 2015

Prevention and treatment of venous thromboembolism during pregnancy

scientific article published on July 2009

Prevention of thromboembolic complications in patients with superficial-vein thrombosis given rivaroxaban or fondaparinux: the open-label, randomised, non-inferiority SURPRISE phase 3b trial

scientific article published on 16 February 2017

Procoagulants for management of bleeding with the new oral anticoagulants

scientific article published on 23 May 2013

Prognostic utility and characterization of cell-free DNA in patients with severe sepsis

scientific article published on 13 August 2012

Prosthetic Heart Valve Thrombosis

scientific article published on December 2016

Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation ⬇️

scientific article published on August 5, 2010

Randomized phase 2 trial comparing JNJ-9375, a thrombin-directed antibody, with apixaban for prevention of venous thrombosis

scientific article published on 13 October 2019

Randomized, blinded trial comparing fondaparinux with unfractionated heparin in patients undergoing contemporary percutaneous coronary intervention: Arixtra Study in Percutaneous Coronary Intervention: a Randomized Evaluation (ASPIRE) Pilot Trial

scientific article published on March 2005

Recent advances in the treatment of venous thromboembolism in the era of the direct oral anticoagulants

scientific article

Recent advances in understanding, diagnosing and treating venous thrombosis

scientific article published on 06 October 2020

Recurrent venous thromboembolism in patients with pulmonary embolism and right ventricular dysfunction: a post-hoc analysis of the Hokusai-VTE study

scientific article

Reduced plasminogen binding and delayed activation render γ'-fibrin more resistant to lysis than γA-fibrin

scientific article published on 15 August 2014

Research and Practice in Thrombosis and Haemostasis - a new ISTH publishing platform for the global thrombosis and hemostasis community.

scientific article published on 30 May 2017

Response by Chan and Weitz to Letter Regarding Article, "Antithrombotic Agents: New Directions in Antithrombotic Therapy"

scientific article published on 06 June 2019

Response by Weitz and Eikelboom to Letter Regarding Article, "Urgent Need to Measure Effects of Direct Oral Anticoagulants".

scientific article published in November 2016

Reversal agents for non-vitamin K antagonist oral anticoagulants

scientific article published on 18 January 2018

Reversal of Direct Oral Anticoagulants: Current Status and Future Directions

scientific article published on 16 February 2017

Risk of recurrent venous thromboembolism according to baseline risk factor profiles

scientific article published on 01 April 2018

Rivaroxaban and Dabigatran for Suppression of Mechanical Heart Valve-Induced Thrombin Generation

scientific article published on 24 December 2019

Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source

article published in 2018

Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness

scientific article published on 26 August 2018

Rivaroxaban for prevention and treatment of venous thromboembolism

scientific article published on 19 February 2019

Rivaroxaban for secondary stroke prevention in patients with embolic strokes of undetermined source: Design of the NAVIGATE ESUS randomized trial

article

Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism

scientific article published on 18 March 2017

Rivaroxaban plus aspirin for cardiovascular protection: Rationale for the vascular dose and dual pathway inhibition

scientific article published on 23 October 2019

Role of phenotypic and genetic testing in managing clopidogrel therapy

scientific article

Role of the tissue factor pathway in the biology of tumor initiating cells.

scientific article

Screening and Diagnostic Clinical Algorithm for Paroxysmal Nocturnal Hemoglobinuria: Expert Consensus.

scientific article published on 12 March 2018

Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa.

scientific article

Selective D-dimer testing for diagnosis of a first suspected episode of deep venous thrombosis: a randomized trial.

scientific article published in January 2013

Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits.

scientific article

Selective factor Xa inhibition for thromboprophylaxis

scientific article published on 24 June 2008

Should Warfarin Be Restarted After Warfarin-Associated Intracranial Hemorrhage?

article published in 2012

Single and multi-functional coating strategies for enhancing the biocompatibility and tissue integration of blood-contacting medical implants

scientific article published on 07 August 2020

Spotlight on unmet needs in stroke prevention: The PIONEER AF-PCI, NAVIGATE ESUS and GALILEO trials

scientific article published on 14 September 2016

Strain history dependence of the nonlinear stress response of fibrin and collagen networks

scientific article

Subtle differences in commercial heparins can have serious consequences for cardiopulmonary bypass patients: A randomized controlled trial

scientific article published on 27 June 2012

Surface modification with polyethylene glycol-corn trypsin inhibitor conjugate to inhibit the contact factor pathway on blood-contacting surfaces.

scientific article

Synergy of Dual Pathway Inhibition in Chronic Cardiovascular Disease

scientific article published on 01 February 2019

Targeted gene sequencing identifies variants in the protein C and endothelial protein C receptor genes in patients with unprovoked venous thromboembolism

scientific article

The MARINER trial of rivaroxaban after hospital discharge for medical patients at high risk of VTE

article

The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V-Special Situations

scientific article published on 31 December 2018

The Postthrombotic Syndrome: Evidence-Based Prevention, Diagnosis, and Treatment Strategies

article

The blood compatibility challenge. Part 1: Blood-contacting medical devices: The scope of the problem

scientific article published on 18 June 2019

The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand

scientific article

The contact activation system as a potential therapeutic target in patients with COVID‐19

scientific article published on 18 April 2020

The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways

scientific article

The mTORC pathway in the antiphospholipid syndrome.

scientific article published in July 2014

The prothrombin time does not predict the risk of recurrent venous thromboembolism or major bleeding in rivaroxaban-treated patients

scientific article published on 15 August 2018

The real decoy: an antidote for factor Xa-directed anticoagulants

scientific article published on 01 September 2013

The status of new anticoagulants

scientific article published on July 2006

Theme 3: Non-invasive management of (recurrent) venous thromboembolism (VTE) and post thrombotic syndrome (PTS).

scientific article published on September 2015

Therapeutic strategies for thrombosis: new targets and approaches

scientific article published on 04 March 2020

Thrombophilia and new anticoagulant drugs

scientific article

Thromboprophylaxis in surgical patients.

scientific article published on April 2003

Thromboprophylaxis with Rivaroxaban in Acutely Ill Medical Patients with Renal Impairment: Insights from the MAGELLAN and MARINER Trials

scientific article published on 23 January 2020

Thrombosis: a major contributor to global disease burden

article by Gary E Raskob et al published 10 October 2014 in Seminars in Thrombosis and Hemostasis

Timing the First Postoperative Dose of Anticoagulants: Lessons Learned From Clinical Trials

scientific article published on 30 April 2015

Transition from apixaban to warfarin--addressing excess stroke, systemic embolism, and major bleeding

scientific article published on 28 September 2014

Translational success stories: development of direct thrombin inhibitors

scientific article

Treatment Challenges in Venous Thromboembolism: An Appraisal of Rivaroxaban Studies

scientific article published on 22 March 2018

Trends in Prescribing Oral Anticoagulants in Canada, 2008-2014.

scientific article

Two doses of rivaroxaban versus aspirin for prevention of recurrent venous thromboembolism. Rationale for and design of the EINSTEIN CHOICE study

scientific article published on 21 May 2015

Unanswered questions in venous thromboembolism

scientific article published on January 2009

Update on heparin: what do we need to know?

scientific article

Upper Extremity DVT versus Lower Extremity DVT: Perspectives from the GARFIELD-VTE Registry

scientific article published on 10 June 2019

Urgent Need to Measure Effects of Direct Oral Anticoagulants.

scientific article

Variation in the Association between Antineoplastic Therapies and Venous Thromboembolism in Patients with Active Cancer

scientific article published on 05 May 2020

Venous thrombosis

scientific article published on 07 May 2015

Vimentin exposed on activated platelets and platelet microparticles localizes vitronectin and plasminogen activator inhibitor complexes on their surface

scientific article published on 14 December 2001

Vitamin K antagonists in heart disease: current status and perspectives (Section III). Position paper of the ESC Working Group on Thrombosis--Task Force on Anticoagulants in Heart Disease

scientific article published on 14 November 2013

Vorapaxar, combination antiplatelet therapy, and stroke

scientific article published in December 2014

Warfarin after bioprosthetic aortic valve implantation

scientific article published on 01 November 2012

Ximelagatran: the first oral direct thrombin inhibitor

scientific article published on April 2004

Zinc delays clot lysis by attenuating plasminogen activation and plasmin-mediated fibrin degradation

scientific article published on 19 March 2015

Zinc promotes clot stability by accelerating clot formation and modifying fibrin structure

scientific article published on 22 October 2015

Zinc: an important cofactor in haemostasis and thrombosis

scientific article published on 10 January 2013

Zn2+ mediates high affinity binding of heparin to the αC domain of fibrinogen

scientific article published on 29 August 2013

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