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List of works by Paul Targett-Adams

3D Spatially Resolved Models of the Intracellular Dynamics of the Hepatitis C Genome Replication Cycle

scientific article published on 30 September 2017

A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein

scientific article published in April 2005

Advanced Hepatitis C Virus Replication PDE Models within a Realistic Intracellular Geometric Environment

scientific article published on 12 February 2019

An integrated transcriptomic and meta-analysis of hepatoma cells reveals factors that influence susceptibility to HCV infection

scientific article (publication date: 2011)

Colony-forming assays reveal enhanced suppression of hepatitis C virus replication using combinations of direct-acting antivirals.

scientific article published on 5 April 2011

Comparison of U2OS and Huh-7 cells for identifying host factors that affect hepatitis C virus RNA replication.

scientific article

Correlation between NS5A dimerization and hepatitis C virus replication

scientific article published on 16 July 2012

Development and characterization of a transient-replication assay for the genotype 2a hepatitis C virus subgenomic replicon

scientific article published on November 2005

Discovery of β-d-2'-deoxy-2'-dichlorouridine nucleotide prodrugs as potent inhibitors of hepatitis C virus replication.

scientific article published on 26 May 2017

Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus.

scientific article

HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors

scientific article published on 3 April 2010

Hepatitis C virus core protein induces lipid droplet redistribution in a microtubule- and dynein-dependent manner.

scientific article

In-cell click labelling of small molecules to determine subcellular localisation

scientific article

Lipid metabolism and HCV infection

scientific article

Live cell analysis and targeting of the lipid droplet-binding adipocyte differentiation-related protein

scientific article (publication date: 2 May 2003)

Mobility analysis of an NS5A-GFP fusion protein in cells actively replicating hepatitis C virus subgenomic RNA.

scientific article published on February 2007

Quantitative Analysis of Hepatitis C NS5A Viral Protein Dynamics on the ER Surface.

scientific article published on 8 January 2018

Signal peptide peptidase cleavage of GB virus B core protein is required for productive infection in vivo

scientific article published in August 2006

Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza

scientific article published on 11 August 2020

Small molecule inhibitors of the hepatitis C virus-encoded NS5A protein ⬇️

scientific article published on September 23, 2012

Small molecules targeting hepatitis C virus-encoded NS5A cause subcellular redistribution of their target: insights into compound modes of action

scientific article

Structural determinants that target the hepatitis C virus core protein to lipid droplets.

scientific article published on 16 May 2006

The Hepatitis C Virus NS4B Protein Can trans-Complement Viral RNA Replication and Modulates Production of Infectious Virus

scientific article (publication date: March 2009)

The herpes simplex virus type 1 DNA packaging protein UL17 is a virion protein that is present in both the capsid and the tegument compartments

scientific article

The thymidine dideoxynucleoside analog, alovudine, inhibits the mitochondrial DNA polymerase γ, impairs oxidative phosphorylation and promotes monocytic differentiation in acute myeloid leukemia

scientific article published on 20 December 2018

The use of AlphaLISA technology to detect interaction between hepatitis C virus-encoded NS5A and cyclophilin A.

scientific article

Transcriptional slippage prompts recoding in alternate reading frames in the hepatitis C virus (HCV) core sequence from strain HCV-1.

scientific article published on July 2008

Transient replication of a hepatitis C virus genotype 1b replicon chimera encoding NS5A-5B from genotype 3a.

scientific article published on 10 October 2013

Visualization of Double-Stranded RNA in Cells Supporting Hepatitis C Virus RNA Replication

scientific article

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