Search filters

List of works by Peter B. Jahrling

3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012

scientific article published on 29 January 2016

A VLP-based vaccine provides complete protection against Nipah virus challenge following multiple-dose or single-dose vaccination schedules in a hamster model

scientific article published on 8 August 2017

A proposal to change existing virus species names to non-Latinized binomials

scientific article published on 16 October 2010

A replication-deficient rabies virus vaccine expressing Ebola virus glycoprotein is highly attenuated for neurovirulence

scientific article

ABSL-4 aerobiology biosafety and technology at the NIH/NIAID integrated research facility at Fort Detrick

scientific article

Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates

scientific article

An Inactivated Rabies Virus-Based Ebola Vaccine, FILORAB1, Adjuvanted With Glucopyranosyl Lipid A in Stable Emulsion Confers Complete Protection in Nonhuman Primate Challenge Models

scientific article published on 24 July 2016

Analysis of the expressed heavy chain variable-region genes of Macaca fascicularis and isolation of monoclonal antibodies specific for the Ebola virus' soluble glycoprotein

scientific article

Animal Models of Ebolavirus Infection

scientific article

Antibody quality and protection from lethal Ebola virus challenge in nonhuman primates immunized with rabies virus based bivalent vaccine

scientific article (publication date: 2013)

Antiviral activity of the EB peptide against zoonotic poxviruses

scientific article published on January 6, 2012

Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis

scientific article

Arenaviruses

article published in 2015

Arenaviruses: Hemorrhagic Fevers

Arenaviruses: Hemorrhagic Fevers

Author Correction: Histology, immunohistochemistry, and in situ hybridization reveal overlooked Ebola virus target tissues in the Ebola virus disease guinea pig model

scientific article published on 15 October 2019

Bolivian Hemorrhagic Fever

Book Review

CD26/DPP4 cell-surface expression in bat cells correlates with bat cell susceptibility to Middle East respiratory syndrome coronavirus (MERS-CoV) infection and evolution of persistent infection

scientific article

CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates

scientific article published on 21 August 2011

Candidate medical countermeasures targeting Ebola virus cell entry

Characterization of Yellow Fever Virus Infection of Human and Non-human Primate Antigen Presenting Cells and Their Interaction with CD4+ T Cells

scientific article

Characterization of the host response to pichinde virus infection in the Syrian golden hamster by species-specific kinome analysis

scientific article

Characterizing monkeypox virus specific CD8+ T cell epitopes in rhesus macaques

scientific article published on 28 September 2013

Clarification and guidance on the proper usage of virus and virus species names

scientific article (publication date: April 2010)

Clinical Characterization of Host Response to Simian Hemorrhagic Fever Virus Infection in Permissive and Refractory Hosts: A Model for Determining Mechanisms of VHF Pathogenesis

scientific article published in 2019

Clinical management of filovirus-infected patients

scientific article

Commentary on Dr. Alan zelicoff's Analysis of the Aralsk outbreak (No. 4).

scientific article published in January 2003

Comparative Analysis of Monkeypox Virus Infection of Cynomolgus Macaques by the Intravenous or Intrabronchial Inoculation Route

scientific article published on December 8, 2010

Comparison of individual and combination DNA vaccines for B. anthracis, Ebola virus, Marburg virus and Venezuelan equine encephalitis virus.

scientific article

Comparison of respiratory inductive plethysmography versus head-out plethysmography for anesthetized nonhuman primates in an animal biosafety level 4 facility

scientific article

Comparison of the protective efficacy of DNA and baculovirus-derived protein vaccines for EBOLA virus in guinea pigs.

scientific article published on April 2003

Controlled viral glycoprotein expression as a safety feature in a bivalent rabies-ebola vaccine

scientific article

Countermeasures to the bioterrorist threat of smallpox

scientific article

Cowpox virus infection of cynomolgus macaques as a model of hemorrhagic smallpox

scientific article published on August 15, 2011

Crimean-Congo hemorrhagic fever: current and future prospects of vaccines and therapies

scientific article

Cynomolgus macaque as an animal model for severe acute respiratory syndrome

scientific article published on 18 April 2006

Demonstration of cross-protective vaccine immunity against an emerging pathogenic Ebolavirus Species

scientific article

Depletion of peripheral blood T lymphocytes and NK cells during the course of ebola hemorrhagic Fever in cynomolgus macaques

scientific article published on January 2004

Detection and identification of Variola virus in fixed human tissue after prolonged archival storage

scientific article

Detection of antibodies against the four subtypes of ebola virus in sera from any species using a novel antibody-phage indicator assay.

scientific article

Development and characterization of rabbit and mouse antibodies against ebolavirus envelope glycoproteins

scientific article published on 13 April 2011

Development of a new vaccine for the prevention of Lassa fever

scientific article

Development of a novel real-time polymerase chain reaction assay for the quantitative detection of Nipah virus replicative viral RNA.

scientific article

Divergent Simian Arteriviruses Cause Simian Hemorrhagic Fever of Differing Severities in Macaques

scientific article published on January 2015

Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses

scientific article

Dual-probe real-time PCR assay for detection of variola or other orthopoxviruses with dried reagents

scientific article published on 10 September 2008

Dynamics of oliveros virus infection in rodents in central Argentina

scientific article

Ebola Virus Disease

Ebola Virus Localization in the Macaque Reproductive Tract during Acute Ebola Virus Disease

scientific article published on 6 February 2018

Ebola Virus Neutralizing Antibodies Detectable in Survivors of theYambuku, Zaire Outbreak 40 Years after Infection

scientific article published on 14 December 2017

Ebola and Marburg viruses: pathogenesis and development of countermeasures

scientific article

Ebola hemorrhagic fever: evaluation of passive immunotherapy in nonhuman primates

scientific article

Ebola virus disease candidate vaccines under evaluation in clinical trials

scientific article published on 10 May 2016

Ebola virus disease: an update on post-exposure prophylaxis

scientific article published on 15 November 2017

Ebola virus genome plasticity as a marker of its passaging history: a comparison of in vitro passaging to non-human primate infection

scientific article

Ebola virus modulates transforming growth factor β signaling and cellular markers of mesenchyme-like transition in hepatocytes

scientific article

Ebola virus, but not Marburg virus, replicates efficiently and without required adaptation in snake cells

scientific article published on 01 July 2018

Ebolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry

scientific article

Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system

scientific article

Essentials of filoviral load quantification

scientific article published on 10 June 2016

Evaluation in nonhuman primates of vaccines against Ebola virus

scientific article

Evaluation of Monkeypox Disease Progression by Molecular Imaging

scientific article published on October 19, 2011

Evaluation of candidate vaccine approaches for MERS-CoV.

scientific article published on 28 July 2015

Evaluation of perceived threat differences posed by filovirus variants

scientific article published on 9 November 2011

Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus

scientific article published on 30 November 2016

Evidence against an important role for infectivity-enhancing antibodies in Ebola virus infections

scientific article published on February 2002

Exotic emerging viral diseases: progress and challenges

scientific article

Exploring the potential of variola virus infection of cynomolgus macaques as a model for human smallpox

scientific article

Filovirus Infections

Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names

scientific article published on 26 September 2014

Filoviruses: Hemorrhagic Fevers

Filoviruses: Hemorrhagic Fevers

Framework for leadership and training of Biosafety Level 4 laboratory workers

scientific article

Fully Human Immunoglobulin G From Transchromosomic Bovines Treats Nonhuman Primates Infected With Ebola Virus Makona Isolate

scientific article published on 22 November 2018

Further characterization of the immune response in mice to inactivated and live rabies vaccines expressing Ebola virus glycoprotein

scientific article

General Disease Pathology in Filoviral and Arenaviral Infections

scholarly article published 24 June 2013

Generation and characterization of large-particle aerosols using a center flow tangential aerosol generator with a non-human-primate, head-only aerosol chamber

scientific article published on April 2015

Genome Sequences of Simian Hemorrhagic Fever Virus Variant NIH LVR42-0/M6941 Isolates (Arteriviridae: Arterivirus).

scientific article

Genomic Characterization of the Genus Nairovirus (Family Bunyaviridae)

scientific article (publication date: 10 June 2016)

Hemorrhagic fever occurs after intravenous, but not after intragastric, inoculation of rhesus macaques with lymphocytic choriomeningitis virus.

scientific article published on June 2002

Hemorrhagic fever viruses as biological weapons: medical and public health management

scientific article

Heparan sulfate is an important mediator of Ebola virus infection in polarized epithelial cells

scientific article published on 31 August 2018

High dose sertraline monotherapy fails to protect rhesus macaques from lethal challenge with Ebola virus Makona

scientific article published on 19 July 2017

Histology, immunohistochemistry, and in situ hybridization reveal overlooked Ebola virus target tissues in the Ebola virus disease guinea pig model

scientific article published on 19 January 2018

Historical Outbreaks of Simian Hemorrhagic Fever in Captive Macaques Were Caused by Distinct Arteriviruses

scientific article published on 13 May 2015

Human Poxviruses

Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs

scientific article (publication date: June 2006)

Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox

scientific article published on March 2004

In Vitro and In Vivo Activity of Amiodarone Against Ebola Virus

scientific article published on 22 November 2018

Inactivated or live-attenuated bivalent vaccines that confer protection against rabies and Ebola viruses

scientific article

Induction of immune responses in mice and monkeys to Ebola virus after immunization with liposome-encapsulated irradiated Ebola virus: protection in mice requires CD4(+) T cells

scientific article

Influenza A and methicillin-resistant Staphylococcus aureus co-infection in rhesus macaques - A model of severe pneumonia.

scientific article

Inhibition of cowpox virus and monkeypox virus infection by mitoxantrone

scientific article published on December 11, 2011

Inhibition of monkeypox virus replication by RNA interference

scientific article

Interferon-β and Interferon-γ Are Weak Inhibitors of Ebola Virus in Cell-Based Assays

scientific article published in May 2017

Interferon-β and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays

scientific article published on 09 December 2013

Intrabronchial inoculation of cynomolgus macaques with cowpox virus

scientific article published on September 21, 2011

Lack of effect of lamivudine on Ebola virus replication

scientific article published on March 2015

Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses

scientific article

Loss in lung volume and changes in the immune response demonstrate disease progression in African green monkeys infected by small-particle aerosol and intratracheal exposure to Nipah virus.

scientific article

MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells.

scientific article

Marburg Virus Disease

MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic fever

scientific article published on April 2006

Mechanisms underlying coagulation abnormalities in ebola hemorrhagic fever: overexpression of tissue factor in primate monocytes/macrophages is a key event

scientific article

Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome: Current Therapeutic Options and Potential Targets for Novel Therapies

scientific article published on 15 November 2017

Middle East respiratory syndrome: obstacles and prospects for vaccine development

scientific article

Modeling [(18)F]-FDG lymphoid tissue kinetics to characterize nonhuman primate immune response to Middle East respiratory syndrome-coronavirus aerosol challenge

scientific article

Molecular imaging of influenza and other emerging respiratory viral infections.

scientific article

Monkeypox virus infection of rhesus macaques induces massive expansion of natural killer cells but suppresses natural killer cell functions

scientific article

Neglected filoviruses

scientific article

Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys

scientific article

New Insights Into Marburg Virus Disease Pathogenesis in the Rhesus Macaque Model

scholarly article by Timothy K Cooper et al published 22 November 2018 in Journal of Infectious Diseases

Nomenclature- and database-compatible names for the two Ebola virus variants that emerged in Guinea and the Democratic Republic of the Congo in 2014.

scientific article

Non-neutralizing antibodies elicited by recombinant Lassa-Rabies vaccine are critical for protection against Lassa fever

scientific article published in Nature Communications

Nonhuman Primate Models of Ebola Virus Disease

scientific article published on 23 June 2017

Nonhuman transferrin receptor 1 is an efficient cell entry receptor for Ocozocoautla de Espinosa virus

scientific article published on 09 October 2013

Nyamiviridae: proposal for a new family in the order Mononegavirales

scientific article

One-Health: a Safe, Efficient, Dual-Use Vaccine for Humans and Animals against Middle East Respiratory Syndrome Coronavirus and Rabies Virus

scientific article published on 2 November 2016

Orthopoxviruses

Overlooking the importance of immunoassays - Authors' reply

scientific article published on 19 September 2016

Pan-Filovirus Serum Neutralizing Antibodies in a Subset of Congolese Ebolavirus Infection Survivors

scientific article published on 13 August 2018

Panmicrobial Oligonucleotide Array for Diagnosis of Infectious Diseases

scientific article (publication date: 2007)

Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection

scientific article published in December 2003

Pathogenesis of Ebola hemorrhagic fever in primate models: evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells

scientific article published in December 2003

Pathogens Causing Viral Hemorrhagic Fevers

Pathologic findings associated with delayed death in nonhuman primates experimentally infected with Zaire Ebola virus

scientific article

Post-exposure prophylactic vaccine candidates for the treatment of human Risk Group 4 pathogen infections

scientific article published on 30 January 2020

Postexposure protection against Marburg haemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human primates: an efficacy assessment

scientific article

Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference

scientific article

Potential impact of a 2-person security rule on BioSafety Level 4 laboratory workers

scientific article published on July 2009

Poxvirus Antigen Staining of Immune Cells as a Biomarker to Predict Disease Outcome in Monkeypox and Cowpox Virus Infection in Non-Human Primates

scientific article published on April 5, 2013

Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody

scientific article published on June 2002

Preclinical Development of Inactivated Rabies Virus-Based Polyvalent Vaccine Against Rabies and Filoviruses

scientific article

Progression of pathogenic events in cynomolgus macaques infected with variola virus

scientific article

Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily

scientific article published on March 2002

Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations

scientific article

Quantification of regional aerosol deposition patterns as a function of aerodynamic particle size in rhesus macaques using PET/CT imaging.

scientific article published on 11 December 2017

Real-time PCR assay to detect smallpox virus

scientific article published on August 2003

Recombinant Lassa Virus Expressing Green Fluorescent Protein as a Tool for High-Throughput Drug Screens and Neutralizing Antibody Assays

scientific article published in 2018

Recombinant adenovirus serotype 26 (Ad26) and Ad35 vaccine vectors bypass immunity to Ad5 and protect nonhuman primates against ebolavirus challenge

scientific article

Recombinant human activated protein C for the postexposure treatment of Ebola hemorrhagic fever

scientific article

Reduced evolutionary rate in reemerged Ebola virus transmission chains

journal article published in 2016

Reidentification of Ebola Virus E718 and ME as Ebola Virus/H.sapiens-tc/COD/1976/Yambuku-Ecran

scientific article

Reorganization and expansion of the nidoviral family Arteriviridae

scientific article

Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection

scientific article published on 19 May 2014

Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus

scientific article published on 20 October 2003

Role of Rodents and Bats in Human Viral Hemorrhagic Fevers

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 1. Biosafety Level 4 Suit Laboratory Suite Entry and Exit Procedures

scientific article (publication date: 3 October 2016)

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 2. General Practices

scientific article

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 3. Aerobiology

scientific article

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 4. Medical Imaging Procedures

scientific article

Sequence of Reston Virus Isolate AZ-1435, an Ebolavirus Isolate Obtained during the 1989-1990 Reston Virus Epizootic in the United States.

scientific article published on 12 January 2017

Simian hemorrhagic fever virus cell entry is dependent on CD163 and uses a clathrin-mediated endocytosis-like pathway

scientific article

Simian hemorrhagic fever virus infection of rhesus macaques as a model of viral hemorrhagic fever: clinical characterization and risk factors for severe disease

scientific article published on October 19, 2011

Smallpox and pan-orthopox virus detection by real-time 3'-minor groove binder TaqMan assays on the roche LightCycler and the Cepheid smart Cycler platforms

scientific article published on February 2004

Smallpox research activities: U.S. interagency collaboration, 2001

scientific article published on July 2002

Specific Detection of Two Divergent Simian Arteriviruses Using RNAscope In Situ Hybridization

scientific article

State-of-the-Art Workshops on Medical Countermeasures Potentially Available for Human Use Following Accidental Exposures to Ebola Virus

scientific article

Systems Kinomics Demonstrates Congo Basin Monkeypox Virus Infection Selectively Modulates Host Cell Signaling Responses as Compared to West African Monkeypox Virus

scientific article published on December 28, 2011

Systems kinomics for characterizing host responses to high-consequence pathogens at the NIH/NIAID Integrated Research Facility-Frederick

scientific article published on 10 April 2014

Taxonomic reorganization of the family Bornaviridae

scientific article

Testing therapeutics in cell-based assays: Factors that influence the apparent potency of drugs

scientific article published on 22 March 2018

The Calcium Channel Blocker Bepridil Demonstrates Efficacy in the Murine Model of Marburg Virus Disease

article

The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis

article

The International Code of Virus Classification and Nomenclature (ICVCN): proposal for text changes for improved differentiation of viral taxa and viruses

scientific article published on 16 February 2013

The International Code of Virus Classification and Nomenclature (ICVCN): proposal to delete Rule 3.41.

scientific article published on 31 August 2012

The NIAID Integrated Research Facility at Frederick, Maryland: a unique international resource to facilitate medical countermeasure development for BSL-4 pathogens

scientific article

The Past Need Not Be Prologue: Recommendations for Testing and Positioning the Most-Promising Medical Countermeasures for the Next Outbreak of Ebola Virus Infection

scientific article published on 01 November 2018

The Role of Viral Protein Phosphorylation During Filovirus Infection

The effect of volume of interest definition on quantification of lymph node immune response to a monkeypox virus infection assessed by (18)F-FDG-PET.

scientific article

The host response to smallpox: analysis of the gene expression program in peripheral blood cells in a nonhuman primate model

scholarly article

The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection

scientific article published on 12 April 2017

The temporal program of peripheral blood gene expression in the response of nonhuman primates to Ebola hemorrhagic fever

scientific article published on January 2007

Towards a vaccine against Ebola virus

scientific article published on December 2003

Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys

scientific article

Triage and management of accidental laboratory exposures to biosafety level-3 and -4 agents

scientific article published on June 2009

Trigger events: enviroclimatic coupling of Ebola hemorrhagic fever outbreaks

scientific article published on November 2004

Two novel simian arteriviruses in captive and wild baboons (Papio spp.).

scientific article

Use of Existing Diagnostic Reverse-Transcription Polymerase Chain Reaction Assays for Detection of Ebola Virus RNA in Semen

scientific article published on 15 September 2015

Vector choice determines immunogenicity and potency of genetic vaccines against Angola Marburg virus in nonhuman primates

scientific article

Vesicular stomatitis virus-based ebola vaccine is well-tolerated and protects immunocompromised nonhuman primates

scientific article published in November 2008

Viral Hemorrhagic Fevers

Viral Hemorrhagic Fevers of Animals Caused by Negative-Strand RNA Viruses

Viral Hemorrhagic Fevers of Animals Caused by Positive-Stranded RNA Viruses

Viral hemorrhagic fevers

scientific article published on June 2006

Virulence differences between monkeypox virus isolates from West Africa and the Congo basin

scientific article

Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA

scientific article published on 5 November 2013

Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae

scientific article published on 29 January 2013

Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae

scientific article published on 23 September 2012

Within-Host Evolution of Simian Arteriviruses in Crab-Eating Macaques

scientific article

[18F]-Fluorodeoxyglucose Uptake in Lymphoid Tissue Serves as a Predictor of Disease Outcome in the Nonhuman Primate Model of Monkeypox Virus Infection

scientific article

“Venezuelan” Hemorrhagic Fever