List of works - Armando Arias

A comparison of viral RNA-dependent RNA polymerases

scientific article published on 20 December 2005

Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA.

scientific article published on 3 August 2004

Virus genomes reveal factors that spread and sustained the Ebola epidemic

scientific article (publication date: 12 April 2017)

Memory in viral quasispecies

scientific article published on April 2000

Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe

scientific article published on 6 December 2006

The structure of a protein primer-polymerase complex in the initiation of genome replication

scientific article

Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin

scientific article published on October 2008

Sequential structures provide insights into the fidelity of RNA replication

scientific article

Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial

scientific article

Favipiravir elicits antiviral mutagenesis during virus replication in vivo

scientific article published on 21 October 2014

A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

scientific article

Preextinction viral RNA can interfere with infectivity

scientific article published on April 2004

Rapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases

scientific article

Viral genome segmentation can result from a trade-off between genetic content and particle stability

scientific article

Duration and fitness dependence of quasispecies memory

scientific article published on January 2002

Molecular intermediates of fitness gain of an RNA virus: characterization of a mutant spectrum by biological and molecular cloning

scientific article published on May 2001

Development of a reverse-genetics system for murine norovirus 3: long-term persistence occurs in the caecum and colon

scientific article

Murine norovirus: propagation, quantification, and genetic manipulation

scientific article

Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding

scientific article

Structure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to Ribavirin

scientific article

Foot-and-mouth disease virus assembly: processing of recombinant capsid precursor by exogenous protease induces self-assembly of pentamers in vitro in a myristoylation-dependent manner

scientific article published on 26 August 2009

Emergence and selection of RNA virus variants: memory and extinction

scientific article

Progress towards the prevention and treatment of norovirus infections

scientific article

Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis.

scientific article

Repeated bottleneck transfers can lead to non-cytocidal forms of a cytopathic virus: implications for viral extinction

scientific article published on 22 November 2007

Fitness increase of memory genomes in a viral quasispecies

scientific article published on May 2004

Norovirus Polymerase Fidelity Contributes to Viral Transmission In Vivo

scientific article

Advances Toward a Norovirus Antiviral: From Classical Inhibitors to Lethal Mutagenesis

scientific article

Influence of genome-scale RNA structure disruption on the replication of murine norovirus--similar replication kinetics in cell culture but attenuation of viral fitness in vivo.

scientific article published on 29 April 2013

5-fluorouracil in lethal mutagenesis of foot-and-mouth disease virus

scientific article published on June 2009

Reverse genetics mediated recovery of infectious murine norovirus.

scientific article

Involvement of a joker mutation in a polymerase-independent lethal mutagenesis escape mechanism

scientific article published on 29 April 2016

Extinction of Zika Virus and Usutu Virus by Lethal Mutagenesis Reveals Different Patterns of Sensitivity to Three Mutagenic Drugs

scholarly article by Maria Rosaria Bassi et al published September 2018 in Antimicrobial Agents and Chemotherapy

Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus

scientific article

Genotypic anomaly in Ebola virus strains circulating in Magazine Wharf area, Freetown, Sierra Leone, 2015.

scientific article published on October 2015

Molecular dissection of a viral quasispecies under mutagenic treatment: positive correlation between fitness loss and mutational load

scientific article published on 12 December 2012

Establishment of a Cell Culture Model of Persistent Flaviviral Infection: Usutu Virus Shows Sustained Replication during Passages and Resistance to Extinction by Antiviral Nucleosides

scientific article published on 17 June 2019

Development of a fluorescence-based method for the rapid determination of Zika virus polymerase activity and the screening of antiviral drugs

article

Effectiveness of Silver Nanoparticles Deposited in Facemask Material for Neutralising Viruses

scientific article published on 3 August 2022

Minor alterations in the intestinal microbiota composition upon Rotavirus infection do not affect susceptibility to DSS colitis

scientific article published on 29 June 2021

Novel Nonnucleoside Inhibitors of Zika Virus Polymerase Identified through the Screening of an Open Library of Antikinetoplastid Compounds

scientific article published in 2021

List of works by Armando Arias

A comparison of viral RNA-dependent RNA polymerases

Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA.

Virus genomes reveal factors that spread and sustained the Ebola epidemic

Memory in viral quasispecies

Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe

The structure of a protein primer-polymerase complex in the initiation of genome replication

Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin

Sequential structures provide insights into the fidelity of RNA replication

Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial

Favipiravir elicits antiviral mutagenesis during virus replication in vivo

A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

Preextinction viral RNA can interfere with infectivity

Rapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases

Viral genome segmentation can result from a trade-off between genetic content and particle stability

Duration and fitness dependence of quasispecies memory

Molecular intermediates of fitness gain of an RNA virus: characterization of a mutant spectrum by biological and molecular cloning

Development of a reverse-genetics system for murine norovirus 3: long-term persistence occurs in the caecum and colon

Murine norovirus: propagation, quantification, and genetic manipulation

Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding

Structure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to Ribavirin

Foot-and-mouth disease virus assembly: processing of recombinant capsid precursor by exogenous protease induces self-assembly of pentamers in vitro in a myristoylation-dependent manner

Emergence and selection of RNA virus variants: memory and extinction

Progress towards the prevention and treatment of norovirus infections

Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis.

Repeated bottleneck transfers can lead to non-cytocidal forms of a cytopathic virus: implications for viral extinction

Fitness increase of memory genomes in a viral quasispecies

Norovirus Polymerase Fidelity Contributes to Viral Transmission In Vivo

Advances Toward a Norovirus Antiviral: From Classical Inhibitors to Lethal Mutagenesis

Influence of genome-scale RNA structure disruption on the replication of murine norovirus--similar replication kinetics in cell culture but attenuation of viral fitness in vivo.

5-fluorouracil in lethal mutagenesis of foot-and-mouth disease virus

Reverse genetics mediated recovery of infectious murine norovirus.

Involvement of a joker mutation in a polymerase-independent lethal mutagenesis escape mechanism

Extinction of Zika Virus and Usutu Virus by Lethal Mutagenesis Reveals Different Patterns of Sensitivity to Three Mutagenic Drugs

Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus

Genotypic anomaly in Ebola virus strains circulating in Magazine Wharf area, Freetown, Sierra Leone, 2015.

Molecular dissection of a viral quasispecies under mutagenic treatment: positive correlation between fitness loss and mutational load

Establishment of a Cell Culture Model of Persistent Flaviviral Infection: Usutu Virus Shows Sustained Replication during Passages and Resistance to Extinction by Antiviral Nucleosides

Development of a fluorescence-based method for the rapid determination of Zika virus polymerase activity and the screening of antiviral drugs

Effectiveness of Silver Nanoparticles Deposited in Facemask Material for Neutralising Viruses

Minor alterations in the intestinal microbiota composition upon Rotavirus infection do not affect susceptibility to DSS colitis

Novel Nonnucleoside Inhibitors of Zika Virus Polymerase Identified through the Screening of an Open Library of Antikinetoplastid Compounds

Mutation, Quasispecies, and Lethal Mutagenesis