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List of works by David A. Eisner

2,3-Butanedione monoxime (BDM) decreases sarcoplasmic reticulum Ca content by stimulating Ca release in isolated rat ventricular myocytes

scientific article published on 01 October 1998

A cellular basis for lidocaine's anti-arrhythmic action [proceedings]

scientific article published on October 1, 1979

A comparison of measurements of intracellular Ca by Ca electrode and optical indicators

scientific article published on 01 December 1984

A functional role for transverse (t-) tubules in the atria

scientific article

A measurable reduction of s.r. Ca content follows spontaneous Ca release in rat ventricular myocytes

scientific article published on 01 November 1997

A mechanism distinct from the L-type Ca current or Na–Ca exchange contributes to Ca entry in rat ventricular myocytes

scientific article published on 24 March 2006

A mechanism for the effects of caffeine on Ca2+ release during diastole and systole in isolated rat ventricular myocytes

scientific article published on 01 November 1990

A model model: a commentary on DiFrancesco and Noble (1985) 'A model of cardiac electrical activity incorporating ionic pumps and concentration changes'.

scientific article

A new technique for simultaneous and in situ measurements of Ca2+ signals in arteriolar smooth muscle and endothelial cells

scientific article published in July 2003

A novel method for absolute calibration of intracellular pH indicators

scientific article published on 01 March 1989

A novel, rapid and reversible method to measure Ca buffering and time-course of total sarcoplasmic reticulum Ca content in cardiac ventricular myocytes

scientific article published on 01 February 1999

A sideways look at sparks, quarks, puffs and blips

scientific article published on 01 November 1996

A small leak may sink a great ship but what does it do to the heart? ⬇️

scientific article published on December 15, 2010

A study of intracellular calcium oscillations in sheep cardiac Purkinje fibres measured at the single cell level

scientific article published on 01 March 1986

A tale of two leaks

scientific article

Active transport and inotropic state in guinea pig left atrium

scientific article published on 01 December 1983

Altered cardiac sarcoplasmic reticulum function of intact myocytes of rat ventricle during metabolic inhibition.

scientific article

Alternans of cardiac calcium cycling in a cluster of ryanodine receptors: a simulation study.

scientific article published on 30 May 2008

Alternans of intracellular calcium: Mechanism and significance

scientific article published on 06 March 2006

An estimate of the calcium content of the sarcoplasmic reticulum in rat ventricular myocytes

article

Analysis of cellular calcium fluxes in cardiac muscle to understand calcium homeostasis in the heart.

scientific article published on 16 May 2007

Another trigger for the heartbeat

scientific article published on 01 November 1998

Arrhythmogenic effects of hypokalaemia on mammalian ventricular muscle [proceedings]

scientific article published in July 1978

Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes

scientific article

Beating to time: calcium clocks, voltage clocks, and cardiac pacemaker activity

scientific article published on 16 January 2009

Biphasic decay of the Ca transient results from increased sarcoplasmic reticulum Ca leak

scientific article

Birthday present for digitalis

scientific article

Bringing European physiologists together

scientific article

Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content

scientific article published on 17 January 2011

Ca-activated chloride current and Na-Ca exchange have different timecourses during sarcoplasmic reticulum Ca release in ferret ventricular myocytes

scientific article published on 01 April 1998

Ca2+ ions can affect intracellular pH in mammalian cardiac muscle

scientific article published in Nature

Caffeine and tetracaine abolish the slow inward calcium current in sheep cardiac Purkinje fibres [proceedings]

scientific article published on August 1, 1979

Caffeine inhibits the agonist-evoked cytosolic Ca2+ signal in mouse pancreatic acinar cells by blocking inositol trisphosphate production ⬇️

scientific article published in Journal of Biological Chemistry

Calcium and Excitation-Contraction Coupling in the Heart

scientific article

Calcium flux balance in the heart

scientific article published on 05 December 2012

Calcium in the Pathophysiology of Atrial Fibrillation and Heart Failure

scientific article published on 04 October 2018

Calcium in the heart: from physiology to disease

scientific article

Calcium signaling in heart: Multiscale, diverse, rapid, local, and remarkable

scientific article published on 13 March 2013

Calcium signalling microdomains and the t-tubular system in atrial mycoytes: potential roles in cardiac disease and arrhythmias

scientific article

Calcium-induced calcium release activates contraction in intact cardiac cells

scientific article published on 01 April 1989

Calsequestrin Mutations and Sudden Death

scientific article published on 01 August 2008

Can changes of ryanodine receptor expression affect cardiac contractility?

scientific article published on 01 March 2000

Carboxyeosin decreases the rate of decay of the [Ca 2+ ] i transient in uterine smooth muscle cells isolated from pregnant rats

scientific article published on 01 December 1998

Cardiac Na-Ca exchange and pH.

scientific article published in April 1996

Changes of SERCA activity have only modest effects on sarcoplasmic reticulum Ca2+ content in rat ventricular myocytes.

scientific article published on 8 August 2011

Changes of intracellular [Ca2+] during refilling of sarcoplasmic reticulum in rat ventricular and vascular smooth muscle

scientific article published on 01 June 1993

Changes of pH affect calcium currents but not outward potassium currents in rat myometrial cells

scientific article published on 01 November 1995

Characterization of an extensive transverse tubular network in sheep atrial myocytes and its depletion in heart failure

scientific article published on 29 July 2009

Characterization of oscillations of intracellular calcium concentration in ferret ventricular muscle

scientific article published on 01 July 1984

Characterization of the electrogenic sodium pump in cardiac Purkinje fibres

scientific article published on 01 June 1980

Chronic vagal nerve stimulation has no effect on tachycardia-induced heart failure progression or excitation-contraction coupling

scientific article published on 01 January 2020

Comparison of subsarcolemmal and bulk calcium concentration during spontaneous calcium release in rat ventricular myocytes.

scientific article

Control of intracellular ionized calcium concentration by sarcolemmal and intracellular mechanisms

scientific article published on February 1984

Dependence of cardiac transverse tubules on the BAR domain protein amphiphysin II (BIN-1)

scientific article

Depressed ryanodine receptor activity increases variability and duration of the systolic Ca2+ transient in rat ventricular myocytes.

scientific article published in October 2002

Diastolic spontaneous calcium release from the sarcoplasmic reticulum increases beat-to-beat variability of repolarization in canine ventricular myocytes after β-adrenergic stimulation.

scientific article

Direct measurements of SR free Ca reveal the mechanism underlying the transient effects of RyR potentiation under physiological conditions

scientific article

Do calcium waves propagate between cells and synchronize alternating calcium release in rat ventricular myocytes? ⬇️

scientific article published on October 22, 2012

Do calcium-activated potassium channels exist in the heart?

scientific article published on December 1983

Does nitric oxide modulate cardiac ryanodine receptor function? Implications for excitation-contraction coupling

scientific article published on 18 September 2007

Does sodium pump inhibition produce the positive inotropic effects of strophanthidine in mammalian cardiac muscle? [proceedings]

scientific article published on November 1, 1979

Does the adenosine A2A receptor stimulate the ryanodine receptor?

scientific article published on 10 November 2006

Effect of adrenaline on the potassium current reversal potential in cardiac Purkinje fibres of the sheep [proceedings] ⬇️

scientific article published on October 1, 1977

Effects of metabolic blockade on the regulation of intracellular calcium in dissociated mouse sensory neurones

scientific article published on 01 May 1990

Effects of metabolic inhibition and changes of intracellular pH on potassium permeability and contraction of rat uterus

scientific article published on 01 June 1993

Effects of rapid application of caffeine on intracellular calcium concentration in ferret papillary muscles.

scientific article

Electro-physics-iology clarified? No spooky action required

scientific article published on 01 September 2019

Enhanced Ca 2+ Current and Decreased Ca 2+ Efflux Restore Sarcoplasmic Reticulum Ca 2+ Content After Depletion

scientific article published on 01 October 1997

Estimate of net calcium fluxes and sarcoplasmic reticulum calcium content during systole in rat ventricular myocytes

article

Evolution of calcium homeostasis: from birth of the first cell to an omnipresent signalling system

scientific article published on 14 June 2007

Factors affecting the propagation of locally activated systolic Ca transients in rat ventricular myocytes

scientific article published on 01 October 1993

Factors controlling changes in intracellular Ca2+ concentration produced by noradrenaline in rat mesenteric artery smooth muscle cells

scientific article published on 01 January 1995

Factors influencing free intracellular calcium concentration in quiescent ferret ventricular muscle.

scientific article

Fluorescence measurements of cytoplasmic and mitochondrial sodium concentration in rat ventricular myocytes

scientific article published on 01 March 1992

From the ryanodine receptor to cardiac arrhythmias.

scientific article published on 10 August 2009

Handing Over

scientific article published on 01 December 2016

Heart failure and the ryanodine receptor: does Occam's razor rule?

scientific article published in November 2002

How calcium signals in myocytes and pericytes are integrated across in situ microvascular networks and control microvascular tone ⬇️

scientific article published on July 16, 2013

How does CaMKIIdelta phosphorylation of the cardiac ryanodine receptor contribute to inotropy?

scientific article published on 21 July 2010

How does endothelin-1 cause a sustained increase in intracellular sodium and calcium which lead to hypertrophy?

scientific article published on 04 October 2006

How structure, Ca signals, and cellular communications underlie function in precapillary arterioles

scientific article published on 27 August 2009

Illuminating Sarcoplasmic Reticulum Calcium

scientific article published on 01 July 2003

Impaired β-adrenergic responsiveness accentuates dysfunctional excitation-contraction coupling in an ovine model of tachypacing-induced heart failure

article by Sarah J Briston et al published 15 March 2011 in Journal of Physiology

In the RyR2(R4496C) mouse model of CPVT, β-adrenergic stimulation induces Ca waves by increasing SR Ca content and not by decreasing the threshold for Ca waves

scientific article

Increased Ca buffering underpins remodelling of Ca2+ handling in old sheep atrial myocytes

scientific article published on 28 July 2017

Increased Vulnerability to Atrial Fibrillation Is Associated With Increased Susceptibility to Alternans in Old Sheep

scientific article published on 01 December 2018

Increasing Ryanodine Receptor Open Probability Alone Does Not Produce Arrhythmogenic Calcium Waves

scientific article published on 16 November 2006

Inhibition of the sodium pump by inorganic phosphate in resealed red cell ghosts

scientific article published on 01 May 1982

Inotropic and arrhythmogenic effects of potassium-depleted solutions on mammalian cardiac muscle.

scientific article published in September 1979

Integrative analysis of calcium signalling in cardiac muscle.

scientific article

Interplay between SERCA and sarcolemmal Ca2+ efflux pathways controls spontaneous release of Ca2+ from the sarcoplasmic reticulum in rat ventricular myocytes

scientific article published on 11 June 2004

Intracellular pH Is Insensitive to Changes in Intracellular Calcium Concentration in Isolated Rat Ventricular Myocytesa

scientific article published on 01 April 1996

Intracellular pH and buffering power measured in isolated single cells from pregnant rat uterus.

scientific article published in September 1991

Life, sudden death, and intracellular calcium

scientific article published in August 2006

Local activation of contraction in isolated rat ventricular myocytes

scientific article published on 01 June 1990

Low sodium inotropy is accompanied by diastolic Ca2+ gain and systolic loss in isolated guinea-pig ventricular myocytes

scientific article

Low-potassium inotropy in cardiac muscle [proceedings]

scientific article published on November 1, 1978

May 2013 sees the celebration of the 80th Birthday of Lionel Opie, founder of the Journal of Molecular and Cellular Cardiology

scientific article published on 15 March 2013

Measurement of Sarcoplasmic Reticulum Ca Content and Sarcolemmal Fluxes during the Transient Stimulation of the Systolic Ca Transient Produced by Caffeine

scientific article published on 01 September 1998

Measurement of calcium entry and exit in quiescent rat ventricular myocytes

scientific article published on 01 August 2000

Measurement of intracellular calcium during the development and relaxation of tonic tension in sheep Purkinje fibres

article

Measurement of sarcoplasmic reticulum Ca2+content and sarcolemmal Ca2+fluxes in isolated rat ventricular myocytes during spontaneous Ca2+release

scientific article published on 01 May 1997

Measurements of intracellular Ca2+ in dissociated type I cells of the rabbit carotid body

scientific article published on 01 September 1989

Mechanisms by which cytoplasmic calcium wave propagation and alternans are generated in cardiac atrial myocytes lacking T-tubules-insights from a simulation study

scientific article published on 3 April 2012

Mechanisms underlying enhanced cardiac excitation contraction coupling observed in the senescent sheep myocardium

scientific article published on 01 December 2004

Membrane potential and ion concentration stability conditions for a cell with a restricted extracellular space ⬇️

scientific article published on November 30, 1979

Metabolic changes during ischaemia and their role in contractile failure in isolated ferret hearts

scientific article published on 01 August 1992

Metabolic consequences of increasing intracellular calcium and force production in perfused ferret hearts

scientific article published on 01 July 1986

Misleading with citation statistics?

scientific article published on 01 May 2019

Modulation of CICR has no maintained effect on systolic Ca2+: simultaneous measurements of sarcoplasmic reticulum and sarcolemmal Ca2+ fluxes in rat ventricular myocytes.

scientific article published in January 2000

Na/Ca exchange: regulator of intracellular calcium and source of arrhythmias in the heart.

scientific article published on March 2007

No Role for the Ryanodine Receptor in Regulating Cardiac Contraction?

scientific article published in October 2000

No role for a voltage sensitive release mechanism in cardiac muscle

scientific article published in February 2003

Normal and pathological excitation-contraction coupling in the heart -- an overview

scientific article

Not all choices are equal

scientific article published on 22 January 2018

PDE5 inhibition improves symptom-free survival and restores transverse tubule loss and catecholamine responsiveness in heart failure

PH-induced changes in calcium: functional consequences and mechanisms of action in guinea pig portal vein.

scientific article published in December 2002

Perturbed atrial calcium handling in an ovine model of heart failure: potential roles for reductions in the L-type calcium current

scientific article

Physiological and pathological modulation of ryanodine receptor function in cardiac muscle.

scientific article published on June 2004

Point/counterpoint: a new feature in the JMCC.

scientific article published in June 2008

Propagating calcium waves initiated by local caffeine application in rat ventricular myocytes

scientific article published on 01 December 1995

Properties of the Fluorescent Sodium Indicator SBFI in Rat and Rabbit Cardiac Myocytes

scientific article published on 01 July 1994

Properties of voltage-activated [Ca2+]i transients in single smooth muscle cells isolated from pregnant rat uterus

scientific article published on 01 September 1998

Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes

scientific article published on 17 December 2009

Reducing ryanodine receptor open probability as a means to abolish spontaneous Ca2+ release and increase Ca2+ transient amplitude in adult ventricular myocytes.

scientific article published on 13 April 2006

Regulation of intracellular and mitochondrial sodium in health and disease

scientific article published on February 2009

Regulation of systolic [Ca2+]i and cellular Ca2+ flux balance in rat ventricular myocytes by SR Ca2+, L-type Ca2+ current and diastolic [Ca2+]i

scientific article published on 11 October 2007

Relationship between intracellular pH and metabolite concentrations during metabolic inhibition in isolated ferret heart

scientific article published on 01 December 1993

Reproducibility of science: Fraud, impact factors and carelessness

scientific article published on 24 October 2017

Sarcoplasmic reticulum Ca-ATPase and heart failure 20 years later

scientific article published on September 2013

Sarcoplasmic reticulum Ca2+ and heart failure: roles of diastolic leak and Ca2+ transport

scientific article published in September 2003

Sarcoplasmic reticulum and mitochondria in cardiac pathophysiology

scientific article published on 13 November 2007

Sarcoplasmic reticulum calcium content fluctuation is the key to cardiac alternans

scientific article published on 29 January 2004

Simultaneous Measurement of Intracellular pH, Calcium, and Tension in Rat Mesenteric Vessels: Effects of Extracellular pH

scientific article published on 01 May 1996

Sodium calcium exchange in the heart: necessity or luxury?

scientific article published in September 2004

Something old, something new: changing views on the cellular mechanisms of heart failure

scientific article

Stability and instability of regulation of intracellular calcium.

scientific article

Stimulation and inhibition by ATP and orthophosphate of the potassium-potassium exchange in resealed red cell ghosts

scientific article published on 01 February 1983

Stimulation of Ca-induced Ca release only transiently increases the systolic Ca transient: measurements of Ca fluxes and sarcoplasmic reticulum Ca.

scientific article published in March 1998

Strophanthidin-induced gain of Ca 2+ occurs during diastole and not systole in guinea-pig ventricular myocytes

scientific article published on 01 April 1999

Systolic [Ca2+ ]i regulates diastolic levels in rat ventricular myocytes

scientific article published on 15 June 2017

The Contribution of Na-Ca Exchange to Relaxation in Mammalian Cardiac Muscle ⬇️

scientific article published on January 1, 1991

The action of adrenaline on pace-maker activity in cardiac Purkinje fibres

scientific article published on 01 July 1978

The control of Ca release from the cardiac sarcoplasmic reticulum: regulation versus autoregulation

scientific article published in June 1998

The control of sarcoplasmic reticulum Ca content in cardiac muscle.

scientific article

The control of tonic tension by membrane potential and intracellular sodium activity in the sheep cardiac Purkinje fibre.

scientific article published in February 1983

The dependence of sodium pumping and tension on intracellular sodium activity in voltage-clamped sheep Purkinje fibres.

scientific article

The dependence on heart rate of the human ventricular action potential duration

scientific article published on 01 October 1982

The effect of 2,5-di-(tert-butyl)-1,4-benzohydroquinone (TBQ) on intracellular Ca2+ handling in rat ventricular myocytes.

scientific article

The effect of acidosis on systolic Ca2+ and sarcoplasmic reticulum calcium content in isolated rat ventricular myocytes

scientific article published on 01 December 2000

The effect of salicylate on Purkinje fibre pace-maker activity [proceedings]

scientific article published on 01 July 1977

The effect of tetracaine on spontaneous Ca2+ release and sarcoplasmic reticulum calcium content in rat ventricular myocytes

scientific article published in August 1997

The effect of tetracaine on stimulated contractions, sarcoplasmic reticulum Ca2+ content and membrane current in isolated rat ventricular myocytes

scientific article published in March 1998

The effects of Na-Ca exchange on membrane currents in sheep cardiac Purkinje fibers

scientific article published on 01 January 1984

The effects of changing intracellular pH on calcium and potassium currents in smooth muscle cells from the guinea-pig ureter

scientific article published in March 1998

The effects of heart rate on the action potential of guinea-pig and human ventricular muscle.

scientific article published in January 1981

The effects of hydrogen peroxide on intracellular calcium handling and contractility in the rat ventricular myocyte

scientific article published on 23 November 2010

The effects of inhibition of the sarcolemmal Ca-ATPase on systolic calcium fluxes and intracellular calcium concentration in rat ventricular myocytes

scientific article published on 01 May 1999

The effects of inhibitors of sarcoplasmic reticulum function on the systolic Ca2+ transient in rat ventricular myocytes

scientific article published on 01 August 1993

The effects of lactic acid production on contraction and intracellular pH during hypoxia in cardiac muscle

scientific article published on 01 September 1993

The effects of low concentrations of caffeine on spontaneous Ca release in isolated rat ventricular myocytes

scientific article published on 01 October 2000

The effects of low sodium solutions on intracellular calcium concentration and tension in ferret ventricular muscle

scientific article published on 01 December 1983

The effects of membrane potential on active and passive sodium transport in Xenopus oocytes

scientific article published on 01 April 1987

The effects of membrane potential, SR Ca2+ content and RyR responsiveness on systolic Ca2+ alternans in rat ventricular myocytes

scientific article published on 19 January 2009

The effects of metabolic inhibition on intracellular calcium and pH in isolated rat ventricular cells

scientific article published on 01 April 1989

The effects of metabolic inhibition on intracellular pH and Ca

scientific article published on 01 September 1989

The effects of rubidium ions and membrane potentials on the intracellular sodium activity of sheep Purkinje fibres.

scientific article published in August 1981

The effects of sodium pump activity on the slow inward current in sheep cardiac Purkinje fibres

scientific article published on 01 January 1982

The effects of thapsigargin on [Ca2+]i in isolated rat mesenteric artery vascular smooth muscle cells

scientific article published on 01 January 1992

The electrogenic Na pump in mammalian cardiac muscle

scientific article published on 01 January 1984

The influence of chemical agents on the level of ionized [Ca2+] in squid axons

scientific article

The interaction of potassium ions and ATP on the sodium pump of resealed red cell ghosts.

scientific article

The mechanism and significance of the slow changes of ventricular action potential duration following a change of heart rate.

scientific article published on 06 March 2009

The new team at JMCC

The quantitative relationship between twitch tension and intracellular sodium activity in sheep cardiac Purkinje fibres

scientific article published on 01 October 1984

The regulation of contraction in cardiac muscle

scientific article published in Nature

The relationship between sodium pump activity and twitch tension in cardiac Purkinje fibres

scientific article published on 01 June 1980

The relative contributions of different intracellular and sarcolemmal systems to relaxation in rat ventricular myocytes

scientific article published on 01 October 1993

The role of [Ca2+]i and [Ca2+] sensitization in the caffeine contracture of rat myocytes: measurement of [Ca2+]i and [caffeine]i

scientific article published on 01 June 1990

The role of intracellular Ca buffers in determining the shape of the systolic Ca transient in cardiac ventricular myocytes

scientific article published in April 2001

The role of intracellular Ca ions in the therapeutic and toxic effects of cardiac glycosides and catecholamines.

scientific article published on January 1986

The role of intracellular sodium activity in the anti-arrhythmic action of local anaesthetics in sheep Purkinje fibres ⬇️

scientific article published on July 1, 1983

The role of sarcolemmal Ca2+-ATPase in the regulation of resting calcium concentration in rat ventricular myocytes

scientific article published on 01 February 1999

The role of the sarcolemmal Ca2+-ATPase in the pH transients associated with contraction in rat smooth muscle

scientific article published on 01 December 1997

The role of the sarcoplasmic reticulum as a Ca2+ sink in rat uterine smooth muscle cells

scientific article published on 01 October 1999

The role of the sodium pump in the effects of potassium-depleted solutions on mammalian cardiac muscle ⬇️

scientific article published on September 1, 1979

The ryanodine receptor: cause or consequence of diabetic heart failure?

scientific article published in July 2000

The sarcolemmal mechanisms involved in the control of diastolic intracellular calcium in isolated rat cardiac trabeculae

scientific article published on 01 October 1996

The sarcoplasmic reticulum and arrhythmogenic calcium release

scientific article published on 13 September 2007

The steady state TTX-sensitive ("window") sodium current in cardiac Purkinje fibres

scientific article (publication date: 16 March 1979)

Thick slurry bevelling: a new technique for bevelling extremely fine microelectrodes and micropipettes

scientific article published in September 1979

Transverse tubules are a common feature in large mammalian atrial myocytes including human.

scientific article published on 12 August 2011

Two centuries of excitation-contraction coupling

scientific article published on June 2004

Ups and downs of calcium in the heart

scientific article published on 26 October 2017

Variability of Spontaneous Ca 2+ Release Between Different Rat Ventricular Myocytes Is Correlated With Na + -Ca 2+ Exchange and [Na + ] i

scientific article published on 01 May 1996

Voltage clamp and tracer flux data: effects of a restricted extra-cellular space ⬇️

scientific article published on August 1, 1979

What is the purpose of the large sarcolemmal calcium flux on each heartbeat?

scientific article published on 12 June 2009

What role does modulation of the ryanodine receptor play in cardiac inotropy and arrhythmogenesis?

scientific article

pH-dependent and -independent effects inhibit Ca(2+)-induced Ca2+ release during metabolic blockade in rat ventricular myocytes

scientific article published on 23 May 2003

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