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List of works by Saul Tzipori

A DNA oligonucleotide microarray for detecting human astrovirus serotypes

scientific article

A Novel Strategy for Development of Recombinant Antitoxin Therapeutics Tested in a Mouse Botulism Model ⬇️

scientific article published on January 6, 2012

A Tetraspecific VHH-Based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection

scientific article published on 13 July 2016

A chimeric protein comprising the glucosyltransferase and cysteine proteinase domains of toxin B and the receptor binding domain of toxin A induces protective immunity against Clostridium difficile infection in mice and hamsters

scientific article

A chimeric toxin vaccine protects against primary and recurrent Clostridium difficile infection

scientific article

A hundred-year retrospective on cryptosporidiosis

scientific article published on 07 March 2008

A pig model of the human gastrointestinal tract ⬇️

scientific article published on April 2, 2013

A piglet model of acute gastroenteritis induced by Shigella dysenteriae Type 1

scientific article

A single VHH-based toxin-neutralizing agent and an effector antibody protect mice against challenge with Shiga toxins 1 and 2.

scientific article

Adenovirus vector expressing Stx1/Stx2-neutralizing agent protects piglets infected with Escherichia coli O157:H7 against fatal systemic intoxication

scientific article

Allele- and Tir-Independent Functions of Intimin in Diverse Animal Infection Models ⬇️

scientific article published on January 31, 2012

An ultrasensitive rapid immunocytotoxicity assay for detecting Clostridium difficile toxins

scientific article published on 23 April 2009

Analysis of the beta-tubulin genes from Enterocytozoon bieneusi isolates from a human and rhesus macaque

scientific article

Antibody Against TcdB, but Not TcdA, Prevents Development of Gastrointestinal and Systemic Clostridium difficile Disease ⬇️

scientific article published on November 2, 2012

Antibody response of healthy adults to recombinant thrombospondin-related adhesive protein of cryptosporidium 1 after experimental exposure to cryptosporidium oocysts

scientific article published on March 2004

Antibody therapy in the management of shiga toxin-induced hemolytic uremic syndrome

scientific article

Antibody-enhanced, Fc gamma receptor-mediated endocytosis of Clostridium difficile toxin A

scientific article published on 23 March 2009

Bacillus subtilis: a temperature resistant and needle free delivery system of immunogens

scientific article

Beneficial effect of oral tigecycline treatment on Clostridium difficile infection in gnotobiotic piglets

scientific article

Bile acids enhance invasiveness of Cryptosporidium spp. into cultured cells

scientific article published on June 2006

Biodistribution and elimination kinetics of systemic Stx2 by the Stx2A and Stx2B subunit-specific human monoclonal antibodies in mice ⬇️

scientific article published on June 1, 2012

Catalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex

scientific article

Characterization of Cryptosporidium meleagridis of human origin passaged through different host species

scientific article

Characterization of RAP, a quorum sensing activator of Staphylococcus aureus.

scientific article

Characterization of subtilase protease in Cryptosporidium parvum and C. hominis

scientific article

Commensal Streptococcus mitis is a unique vector for oral mucosal vaccination

scientific article published on 15 December 2014

Comparison of two label-free global quantitation methods, APEX and 2D gel electrophoresis, applied to the Shigella dysenteriae proteome

scientific article published on 29 June 2009

Continuous culture of Cryptosporidium parvum using hollow fiber technology

scientific article published on September 2015

Cryopreservation of infectious Cryptosporidium parvum oocysts

scientific article published in Nature Communications

Cryptosporidiosis and microsporidiosis in ugandan children with persistent diarrhea with and without concurrent infection with the human immunodeficiency virus.

scientific article published on November 2005

Cryptosporidiosis in Rhesus Macaques Challenged During Acute and Chronic Phases of SIV Infection ⬇️

scientific article published on March 27, 2011

Cryptosporidiosis in children in Sub-Saharan Africa: a lingering challenge

scientific article published on October 2008

Cryptosporidiosis: biology, pathogenesis and disease

scientific article

Cryptosporidium hominis gene catalog: a resource for the selection of novel Cryptosporidium vaccine candidates

scientific article published on 19 October 2016

Cryptosporidium meleagridis: infectivity in healthy adult volunteers

scientific article

Cryptosporidium muris: infectivity and illness in healthy adult volunteers

scientific article

Cryptosporidium parvum in children with diarrhea in Mulago Hospital, Kampala, Uganda.

scientific article published on June 2003

Detection and genotyping of oocysts of Cryptosporidium parvum by real-time PCR and melting curve analysis

scientific article

Development of SYN-004, an oral beta-lactamase treatment to protect the gut microbiome from antibiotic-mediated damage and prevent Clostridium difficile infection

scientific article

Development of a Bacillus subtilis-based rotavirus vaccine

scientific article

Development of patent infection in immunosuppressed C57Bl/6 mice with a single Cryptosporidium meleagridis oocyst.

scientific article

Effects of surotomycin on Clostridium difficile viability and toxin production in vitro

scientific article published on 4 May 2015

Efficacy, heat stability and safety of intranasally administered Bacillus subtilis spore or vegetative cell vaccines expressing tetanus toxin fragment C.

scientific article published on 13 August 2010

Efficient serum clearance of botulinum neurotoxin achieved using a pool of small antitoxin binding agents

scientific article

Enhanced Actin Pedestal Formation by Enterohemorrhagic Escherichia coli O157:H7 Adapted to the Mammalian Host ⬇️

scientific article published on November 15, 2011

Enterocytozoon bieneusi among children with diarrhea attending Mulago Hospital in Uganda.

scientific article

Erratum: Corrigendum: The genome of Cryptosporidium hominis

scientific article published in Nature

EspFU, a type III-translocated effector of actin assembly, fosters epithelial association and late-stage intestinal colonization by E. coli O157:H7.

scientific article published on 6 December 2007

Essential role of the glucosyltransferase activity in Clostridium difficile toxin-induced secretion of TNF-alpha by macrophages

scientific article published on 24 March 2009

Evaluation of Fab and F(ab')2 fragments and isotype variants of a recombinant human monoclonal antibody against Shiga toxin 2.

scientific article

Evaluation of virulent and live Shigella sonnei vaccine candidates in a gnotobiotic piglet model ⬇️

scientific article published on May 15, 2013

Evidence for mitochondrial-derived alternative oxidase in the apicomplexan parasite Cryptosporidium parvum: a potential anti-microbial agent target

scientific article published in March 2004

Evidence for the shikimate pathway in apicomplexan parasites

scientific article published in Nature

Expectoration of Cryptosporidium Parasites in Sputum of Human Immunodeficiency Virus-Positive and -Negative Adults

scientific article published on 5 February 2018

Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium

scientific article

Factors contributing to spontaneous Enterocytozoon bieneusi infection in simian immunodeficiency virus-infected macaques

scientific article published in December 2006

Failure to propagate Cryptosporidium spp. in cell-free culture

scientific article

Frequent Occurrence of Mixed Enterocytozoon bieneusi Infections in Humans ⬇️

scientific article published on June 28, 2013

Genomic survey of the non-cultivatable opportunistic human pathogen, Enterocytozoon bieneusi

scientific article

Gnotobiotic piglet infection model for evaluating the safe use of antibiotics against Escherichia coli O157:H7 infection

scientific article

Human Stx2-specific monoclonal antibodies prevent systemic complications of Escherichia coli O157:H7 infection

scientific article

Human antibody against shiga toxin 2 administered to piglets after the onset of diarrhea due to Escherichia coli O157:H7 prevents fatal systemic complications

scientific article

Hyperimmune bovine colostrum as a novel therapy to combat Clostridium difficile infection

scientific article published on 7 November 2014

Hyperimmune bovine colostrum for treatment of GI infections: a review and update on Clostridium difficile

scientific article published on 22 February 2013

Identification of genotypically mixed Cryptosporidium parvum populations in humans and calves

scientific article published on August 2003

Immune-based treatment and prevention of Clostridium difficile infection

scientific article

In vitro and in vivo protective efficacies of antibodies that neutralize the RNA N-glycosidase activity of Shiga toxin 2.

scientific article

In vivo versus in vitro protein abundance analysis of Shigella dysenteriaetype 1 reveals changes in the expression of proteins involved in virulence, stress and energy metabolism ⬇️

scientific article published on June 24, 2011

Infection With Cryptosporidium hominis Provides Incomplete Protection of the Host Against Cryptosporidium parvum ⬇️

scientific article published on January 25, 2012

Infection with anthroponotic Cryptosporidium parvum does not fully protect the host against a subsequent challenge with C. hominis

scientific article published on 18 January 2018

Inferences about the global population structures of Cryptosporidium parvum and Cryptosporidium hominis

scientific article published on 03 October 2008

Interaction ofCryptosporidium parvumwith mouse dendritic cells leads to their activation and parasite transportation to mesenteric lymph nodes ⬇️

scientific article published on September 10, 2013

Intracellular neutralization of shiga toxin 2 by an a subunit-specific human monoclonal antibody

scientific article

Introduction. Cryptosporidiosis: current trends and challenges.

scientific article

Involvement of host calpain in the invasion of Cryptosporidium parvum ⬇️

scientific article published on November 16, 2010

Kinetics of Cryptosporidium parvum-specific cytokine responses in healing and nonhealing murine models of C. parvum infection.

scientific article published on 29 July 2005

MBX-500 Is Effective for Treatment of Clostridium difficile Infection in Gnotobiotic Piglets ⬇️

scientific article published on May 20, 2013

MBX-500, a Hybrid Antibiotic with In Vitro and In Vivo Efficacy against Toxigenic Clostridium difficile ⬇️

scientific article published on June 25, 2012

Microsporidiosis and malnutrition in children with persistent diarrhea, Uganda

scientific article published on January 2009

Molecular characterization of ribonucleotide reductase from Cryptosporidium parvum

scientific article published in June 2002

Monoclonal antibodies against Enterocytozoon bieneusi of human origin

scientific article

Patterns of genome evolution among the microsporidian parasites Encephalitozoon cuniculi, Antonospora locustae and Enterocytozoon bieneusi

scientific article

Piglet models of acute or chronic Clostridium difficile illness.

scientific article

Prevalence of Enterocytozoon bieneusi in swine: an 18-month survey at a slaughterhouse in Massachusetts

scientific article published on May 2002

Production and characterization of monoclonal antibodies against Enterocytozoon bieneusi purified from rhesus macaques

scientific article

Production and characterization of protective human antibodies against Shiga toxin 1

scientific article

Proteomic View of Interactions of Shiga Toxin-Producing Escherichia coli with the Intestinal Environment in Gnotobiotic Piglets

scientific article

Purification of Enterocytozoon bieneusi from stools and production of specific antibodies

scientific article

Quantitative tracking of Cryptosporidium infection in cell culture with CFSE.

scientific article published on December 2006

Rapid Displacement of Cryptosporidium parvum Type 1 by Type 2 in Mixed Infections in Piglets ⬇️

scientific article published on October 1, 2003

Recombinant proteins of Cryptosporidium parvum induce proliferation of mesenteric lymph node cells in infected mice

scientific article

Respiratory cryptosporidiosis in HIV-seronegative children in Uganda: potential for respiratory transmission

scientific article

Selective Evolution of Ligands by Exponential Enrichment to Identify RNA Aptamers against Shiga Toxins

scientific article

Self-regulation of Candida albicans population size during GI colonization

scientific article

Sensitivity and specificity of a monoclonal antibody-based fluorescence assay for detecting Enterocytozoon bieneusi spores in feces of simian immunodeficiency virus-infected macaques

scientific article

Serial propagation of the microsporidian Enterocytozoon bieneusi of human origin in immunocompromised rodents

scientific article published on August 2006

Sheep Monoclonal Antibodies Prevent Systemic Effects of Botulinum Neurotoxin A1 ⬇️

scientific article published on December 1, 2012

Shiga toxin 2-specific but not shiga toxin 1-specific human monoclonal antibody protects piglets challenged with enterohemorrhagic Escherichia coli producing shiga toxin 1 and shiga toxin 2.

scientific article

Shikimate pathway in apicomplexan parasites

Single-domain antibodies pinpoint potential targets within Shigella invasion plasmid antigen D of the needle tip complex for inhibition of type III secretion

scientific article

Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A.

scientific article published on 8 July 2017

Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain complexed with small-molecule inhibitors highlight active-site flexibility

scientific article

Stx2-specific human monoclonal antibodies protect mice against lethal infection with Escherichia coli expressing Stx2 variants

scientific article

Subtype analysis of Cryptosporidium isolates from children in Uganda

scientific article published on October 2006

Synthesis, characterization and development of a high-throughput methodology for the discovery of botulinum neurotoxin a inhibitors

scientific article

Systemic dissemination of Clostridium difficile toxins A and B is associated with severe, fatal disease in animal models

scientific article published on 5 December 2011

Systemically administered IgG anti-toxin antibodies protect the colonic mucosa during infection with Clostridium difficile in the piglet model

scientific article

Tegumental Phosphodiesterase SmNPP-5 Is a Virulence Factor for Schistosomes ⬇️

scientific article published on August 8, 2011

The Shigella dysenteriae serotype 1 proteome, profiled in the host intestinal environment, reveals major metabolic modifications and increased expression of invasive proteins

scientific article

The genome of Cryptosporidium hominis

scientific article

The immune response of two microbial antigens delivered intradermally, sublingually, or the combination thereof

scientific article published on 8 August 2014

The reduced genome of the parasitic microsporidian Enterocytozoon bieneusi lacks genes for core carbon metabolism

scientific article

The roles of toxin A and toxin B in Clostridium difficile infection: insights from the gnotobiotic piglet model

scientific article

The shikimate pathway and its branches in apicomplexan parasites

scientific article

The therapeutic efficacy of azithromycin and nitazoxanide in the acute pig model of Cryptosporidium hominis

scientific article published on 3 October 2017

Therapeutic evaluation of polyamine analogue drug candidates against Enterocytozoon bieneusi in a SCID mouse model

scientific article published on 16 March 2009

Transcriptome analysis of pig intestinal cell monolayers infected with Cryptosporidium parvum asexual stages

scientific article published on 12 March 2018

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