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List of works by Matthew H. Todd

A Fluorescent “Allosteric Scorpionand” Complex Visualizes a Biological Recognition Event ⬇️

scientific article published on 09 January 2013

A click fluorophore sensor that can distinguish Cu(II) and Hg(II) via selective anion-induced demetallation

scientific article

A direct method for the N-tetraalkylation of azamacrocycles

scientific article published on 18 November 2016

A kernel for open source drug discovery in tropical diseases

scientific article

A kernel for the Tropical Disease Initiative

scientific article

A synthetically simple, click-generated cyclam-based zinc(II) sensor

scientific article

Activity of praziquantel enantiomers and main metabolites against Schistosoma mansoni.

scientific article

Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma.

scientific article published on 26 April 2018

Amino acid derived heterocycles: lewis acid catalyzed and radical cyclizations from peptide acetals

scientific article

An open source pharma roadmap

scientific article (publication date: 18 April 2017)

Antitubercular Bis-Substituted Cyclam Derivatives: Structure-Activity Relationships and in Vivo Studies.

scientific article

Asymmetric autocatalysis: product recruitment for the increase in the chiral environment (PRICE).

scientific article

Can we measure catalyst efficiency in asymmetric chemical reactions? A theoretical approach

scientific article published on 19 November 2009

Chemical sensors that incorporate click-derived triazoles

scientific article published on 04 March 2011

Computer-aided organic synthesis

scientific article

Copper, nickel, and zinc cyclam-amino acid and cyclam-peptide complexes may be synthesized with "click" chemistry and are noncytotoxic

scientific article

Cyclam-based "clickates": homogeneous and heterogeneous fluorescent sensors for Zn(II).

scientific article published in April 2010

Design and synthesis of new tetrazolyl- and carboxy-biphenylylmethyl-quinazolin-4-one derivatives as angiotensin II AT1 receptor antagonists

scientific article published in March 2006

Drugs for the control of parasitic diseases: current status and development in schistosomiasis ⬇️

scientific article published on November 1, 2003

Easy-To-Synthesize Spirocyclic Compounds Possess Remarkable in Vivo Activity against Mycobacterium tuberculosis

scientific article published on 12 December 2018

Effective methods for the biotinylation of azamacrocycles

scientific article published on 29 September 2007

Efficient Synthesis and Anti-Tubercular Activity of a Series of Spirocycles: An Exercise in Open Science

scientific article

Efficient deprotection of F-BODIPY derivatives: removal of BF2 using Brønsted acids

scientific article

Enhancing the usefulness of cross dehydrogenative coupling reactions with a removable protecting group ⬇️

scientific article published on July 2, 2013

Experiences with a researcher-centric ELN.

scientific article published on 20 October 2014

Experiences with a researcher-centric ELN† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc02128b Click here for additional data file

scientific article published on 20 October 2014

In vitro metabolic profile and in vivo antischistosomal activity studies of (η(6)-praziquantel)Cr(CO)3 derivatives

scientific article published on 12 November 2013

Incorporating a piperidinyl group in the fluorophore extends the fluorescence lifetime of click-derived cyclam-naphthalimide conjugates

scientific article

Incorporation of Bulky and Cationic Cyclam-Triazole Moieties into Marimastat Can Generate Potent MMP Inhibitory Activity without Inducing Cytotoxicity

scientific article published on 12 June 2013

Is actin the praziquantel receptor?

scientific article published on 06 July 2007

Metal complexes as a promising source for new antibiotics

scientific article published on 12 February 2020

Molecular Docking with Open Access Software: Development of an Online Laboratory Handbook and Remote Workflow for Chemistry and Pharmacy Master’s Students to Undertake Computer-Aided Drug Design

scientific article published in 2021

Molecular Switches for any pH: A Systematic Study of the Versatile Coordination Behaviour of Cyclam Scorpionands

scientific article

N-Aryl Groups Are Ubiquitous in Cross-Dehydrogenative Couplings Because They Stabilize Reactive Intermediates

scientific article published on 18 May 2017

Neuroprotective peptide-macrocycle conjugates reveal complex structure-activity relationships in their interactions with amyloid β.

scientific article published on 18 August 2014

Non-Classical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open Source Antimalarials

scientific article published on 17 July 2020

Nontoxic Metal-Cyclam Complexes, a New Class of Compounds with Potency against Drug-Resistant Mycobacterium tuberculosis

scientific article published on 23 May 2016

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

scientific article published on 14 September 2016

Open Source Research — the Power of Us

scientific article (publication date: 2006)

Open access and open source in chemistry

scientific article

Open science approaches to COVID-19

scientific article published on 25 August 2020

Open science is a research accelerator ⬇️

scientific article published on September 23, 2011

Open source drug discovery - a limited tutorial

scientific article (publication date: 2014)

Oxidative arylation of isochroman.

scientific article published on 29 December 2011

Polyamide-scorpion cyclam lexitropsins selectively bind AT-rich DNA independently of the nature of the coordinated metal

scientific article

Praziquantel derivatives I: Modification of the aromatic ring

scientific article published on 23 May 2007

Recent Advances in Macrocyclic Fluorescent Probes for Ion Sensing.

scientific article published on 25 January 2017

Resolution of Praziquantel ⬇️

scientific article published on September 20, 2011

Responsive metal complexes: a click-based "allosteric scorpionate" complex permits the detection of a biological recognition event by EPR/ENDOR spectroscopy

scientific article published in January 2009

SCINDR - The SCience INtroDuction Robot that will Connect Open Scientists

scientific article published on 27 July 2016

Six Laws of Open Source Drug Discovery

scientific article published on 15 October 2019

Studies on the Synthesis, Characterisation and Reactivity of Aromatic Diboronic Acids

Synthesis and DNA binding ability of cyclam-amino acid conjugates

scientific article

Synthesis and Evaluation of 1,8-Disubstituted-Cyclam/Naphthalimide Conjugates as Probes for Metal Ions

scientific article published on 03 August 2016

Tele-substitution Reactions in the Synthesis of a Promising Class of 1,2,4-Triazolo[4,3-a]pyrazine-Based Antimalarials

scientific article published on 13 August 2020

Ten simple rules for cultivating open science and collaborative R&D;

scientific article (publication date: 2013)

The outcome of the oxidations of unusual enediamide motifs is governed by the stabilities of the intermediate iminium ions

scientific article

The past, present and future of anti-malarial medicines

scholarly article published by Matthew H. Todd in 2019

The properties and performance of a pH-responsive functionalised nanoparticle

scientific article published in January 2014

The use of FTICR-MS to detect chemical tags from a combinatorial library

scientific article published in November 2002

Using an open source model to accelerate schistosomiasis drug research

scientific article published in January 2015

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