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List of works by Johan Vekemans

"Immunization of newborns in the tropics." The Gambia, 25-27 November 1999.

scientific article published in October 2000

A Phase IIa Controlled Human Malaria Infection and Immunogenicity Study of RTS,S/AS01E and RTS,S/AS01B Delayed Fractional Dose Regimens in Malaria-Naïve Adults

scientific article published on 20 July 2020

A field trial to assess a blood-stage malaria vaccine

scientific article published on September 2011

A new tuberculosis vaccine: breakthrough, challenges, and a call for collaboration

scientific article published on 30 January 2019

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

scientific article

A randomized trial assessing the safety and immunogenicity of AS01 and AS02 adjuvanted RTS,S malaria vaccine candidates in children in Gabon

scientific article

A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS,S/AS01E

scientific article

Ad35.CS.01-RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults

scientific article published on 6 July 2015

Antigen-specific IL-2 secretion correlates with NK cell responses after immunization of Tanzanian children with the RTS,S/AS01 malaria vaccine

scientific article

Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care ⬇️

scientific article published on August 4, 2011

Avidity of anti-circumsporozoite antibodies following vaccination with RTS,S/AS01E in young children

scientific article

Building momentum for malaria vaccine research and development: key considerations

scientific article published on 23 November 2020

Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01E and Protection against P falciparum Clinical Malaria ⬇️

scientific article published on October 6, 2011

Correction: Randomized Controlled Trial of RTS,S/AS02D and RTS,S/AS01E Malaria Candidate Vaccines Given According to Different Schedules in Ghanaian Children.

scientific article

Correction: Safety of the Malaria Vaccine Candidate, RTS,S/AS01 in 5 to 17 Month Old Kenyan and Tanzanian Children

article by John Lusingu et al published 28 December 2010 in PLOS ONE

Correction: Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children.

scientific article

Deficient IL-12(p35) gene expression by dendritic cells derived from neonatal monocytes

scientific article published in February 2001

Delay in motor development of twins in Africa: a prospective cohort study

scientific article published in August 2003

Demonstration of the Blood-Stage Plasmodium falciparum Controlled Human Malaria Infection Model to Assess Efficacy of the P. falciparum Apical Membrane Antigen 1 Vaccine, FMP2.1/AS01

scientific article published on 4 February 2016

Design of a phase III multicenter trial to evaluate the efficacy of the RTS,S/AS01 malaria vaccine in children across diverse transmission settings in Africa

scientific article

Development of standardized laboratory methods and quality processes for a phase III study of the RTS, S/AS01 candidate malaria vaccine

scientific article published on 4 August 2011

Development of the RTS,S/AS malaria candidate vaccine

scientific article published in December 2009

Dissociation between tuberculin skin test and in vitro IFN-gamma responses following neonatal BCG vaccination

scientific article published on 26 August 2005

Effect of ingested human antibodies induced by RTS, S/AS01 malaria vaccination in children on Plasmodium falciparum oocyst formation and sporogony in mosquitoes

scientific article

Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children ⬇️

scientific article

Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5-17 months in Kenya and Tanzania: a randomised controlled trial

scientific article published on 13 January 2011

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

scientific article

Estimates of the Burden of Group B Streptococcal Disease Worldwide for Pregnant Women, Stillbirths, and Children

scientific article published in November 2017

Evaluation of the safety and immunogenicity of the RTS,S/AS01 E malaria candidate vaccine when integrated in the expanded program of immunization

scientific article published on October 2010

Extended safety, immunogenicity and efficacy of a blood-stage malaria vaccine in malian children: 24-month follow-up of a randomized, double-blinded phase 2 trial

scientific article

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

scientific article

Four year immunogenicity of the RTS,S/AS02(A) malaria vaccine in Mozambican children during a phase IIb trial

scientific article published on 7 April 2011

Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study

scientific article

From the circumsporozoite protein to the RTS, S/AS candidate vaccine

scientific article published on 30 January 2010

Group B Streptococcal Disease Worldwide for Pregnant Women, Stillbirths, and Children: Why, What, and How to Undertake Estimates?

scientific article

Group B Streptococcus vaccine development: present status and future considerations, with emphasis on perspectives for low and middle income countries

scientific article

HIV immunoprophylaxis: preparing the pathway from proof of concept to policy decision and use

scientific article published on 27 November 2019

Hepatitis B immunisation induces higher antibody and memory Th2 responses in new-borns than in adults

scientific article published on 01 January 2004

Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions

scientific article published on 2 November 2017

Immune response to the hepatitis B antigen in the RTS,S/AS01 malaria vaccine, and co-administration with pneumococcal conjugate and rotavirus vaccines in African children: A randomized controlled trial

scientific article published on 13 April 2018

Immune responses to mycobacterial antigens in the Gambian population: implications for vaccines and immunodiagnostic test design

scientific article

Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)

scientific article (publication date: 11 April 2011)

Infant Group B Streptococcal Disease Incidence and Serotypes Worldwide: Systematic Review and Meta-analyses

scientific article published in November 2017

Influence of Mycobacterium bovis Bacillus Calmette-Guerin on Antibody and Cytokine Responses to Human Neonatal Vaccination

article

Intrapartum Antibiotic Chemoprophylaxis Policies for the Prevention of Group B Streptococcal Disease Worldwide: Systematic Review

scientific article published in November 2017

Long-term immunogenicity and immune memory response to the hepatitis B antigen in the RTS,S/AS01E malaria vaccine in African children: a randomized trial

scientific article published on 17 January 2020

Long-term safety and efficacy of the RTS,S/AS02A malaria vaccine in Mozambican children

scientific article published on August 2009

Maternal Colonization With Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses

scientific article published in November 2017

Maternal Disease With Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses

scientific article published in November 2017

Maternal immunization against Group B streptococcus: World Health Organization research and development technological roadmap and preferred product characteristics.

scientific article published on 2 February 2018

Meeting report: WHO consultation on Respiratory Syncytial Virus (RSV) vaccine development, Geneva, 25-26 April 2016.

scientific article

Molecular basis of allele-specific efficacy of a blood-stage malaria vaccine: vaccine development implications

scientific article published on 29 November 2012

Monophosphoryl lipid A activates both human dendritic cells and T cells

scientific article published on 01 January 2002

Neonatal Encephalopathy With Group B Streptococcal Disease Worldwide: Systematic Review, Investigator Group Datasets, and Meta-analysis

scientific article

Neonatal bacillus Calmette-Guérin vaccination induces adult-like IFN-gamma production by CD4+ T lymphocytes

scientific article published in May 2001

Neurodevelopmental Impairment in Children After Group B Streptococcal Disease Worldwide: Systematic Review and Meta-analyses

scientific article published in November 2017

New hope for tuberculosis vaccines

scientific article published on 01 July 2019

Phase 1/2a Trial of Plasmodium vivax Malaria Vaccine Candidate VMP001/AS01B in Malaria-Naive Adults: Safety, Immunogenicity, and Efficacy

scientific article

Plasmodium falciparum malaria vaccines in development

scientific article published on March 2008

Polarization of PPD-specific T-cell response of patients with tuberculosis from Th0 to Th1 profile after successful antimycobacterial therapy or in vitro conditioning with interferon-alpha or interleukin-12.

scientific article published in February 2001

Pooled analysis of safety data from pediatric Phase II RTS,S/AS malaria candidate vaccine trials ⬇️

scientific article published on December 1, 2011

Potential effect of age of BCG vaccination on global paediatric tuberculosis mortality: a modelling study

scientific article published on 01 December 2019

Predicting RTS,S Vaccine-Mediated Protection from Transcriptomes in a Malaria-Challenge Clinical Trial

scientific article published on 23 May 2017

Preferred product characteristics for therapeutic vaccines to improve tuberculosis treatment outcomes: Key considerations from World Health Organization consultations

scientific article published on 13 November 2019

Preterm Birth Associated With Group B Streptococcus Maternal Colonization Worldwide: Systematic Review and Meta-analyses

scientific article published in November 2017

RTS,S malaria vaccine efficacy and immunogenicity during Plasmodium falciparum challenge is associated with HLA genotype

scientific article published on 10 February 2018

Randomized controlled trial of RTS,S/AS02D and RTS,S/AS01E malaria candidate vaccines given according to different schedules in Ghanaian children

scientific article published on 2 October 2009

Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02D malaria vaccine in infants living in a malaria-endemic region ⬇️

scientific article published on January 8, 2013

Report from the World Health Organization’s third Product Development for Vaccines Advisory Committee (PDVAC) meeting, Geneva, 8–10th June 2016

scientific article (publication date: March 2017)

Research and development of new tuberculosis vaccines: a review

article

Respiratory syncytial virus vaccine research and development: World Health Organization technological roadmap and preferred product characteristics

scientific article published on 25 January 2018

Risk of Early-Onset Neonatal Group B Streptococcal Disease With Maternal Colonization Worldwide: Systematic Review and Meta-analyses

scientific article published in November 2017

Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP.

scientific article published on 15 June 2016

Safety and Immunogenicity of Seven Dosing Regimens of the Candidate RTS,S/AS01E Malaria Vaccine Integrated within an Expanded Program on Immunization Regimen: A Phase II, Single-Center, Open, Controlled Trial in Infants in Malawi

scientific article published on 9 February 2018

Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP

scientific article published on 09 October 2018

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

scientific article published on 08 December 2020

Safety and efficacy of the RTS, S/AS01 E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial

scientific article

Safety and immunogenicity of RTS,S/AS01 malaria vaccine in infants and children with WHO stage 1 or 2 HIV disease: a randomised, double-blind, controlled trial

scientific article published on 6 July 2016

Safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants

scientific article

Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

scientific article

Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children

scientific article (publication date: 29 November 2010)

Safety, immunogenicity and duration of protection of the RTS,S/AS02(D) malaria vaccine: one year follow-up of a randomized controlled phase I/IIb trial

scientific article (publication date: 4 November 2010)

Serocorrelates of protection against infant group B streptococcus disease

scientific article published on 22 January 2019

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

scientific article (publication date: 2011)

Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

scientific article published in February 2021

Stillbirth With Group B Streptococcus Disease Worldwide: Systematic Review and Meta-analyses

scientific article

Strain-specific Plasmodium falciparum growth inhibition among Malian children immunized with a blood-stage malaria vaccine

scientific article

Strain-specific Plasmodium falciparum multifunctional CD4(+) T cell cytokine expression in Malian children immunized with the FMP2.1/AS02A vaccine candidate

scientific article published on 14 April 2016

T cell responses to the RTS,S/AS01e and RTS,S/AS02D malaria candidate vaccines administered according to different schedules to Ghanaian children

scientific article (publication date: 27 April 2011)

T cell responses to vaccines in infants: defective IFNgamma production after oral polio vaccination

scientific article published in March 2002

Template protocol for clinical trials investigating vaccines--focus on safety elements

scientific article

The March Toward Malaria Vaccines

scientific article

The case for assessing the full value of new tuberculosis vaccines

scientific article published on 20 March 2020

The complex challenges of HIV vaccine development require renewed and expanded global commitment

scientific article published on 02 December 2019

The effect of immunization schedule with the malaria vaccine candidate RTS,S/AS01E on protective efficacy and anti-circumsporozoite protein antibody avidity in African infants

scientific article

The march toward malaria vaccines

scientific article published on 28 August 2015

The path to group A Streptococcus vaccines: WHO research and development technology roadmap and preferred product characteristics

article

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates

scholarly article by Natalie I Mazur et al published October 2018 in Lancet Infectious Diseases

The role of immune correlates of protection on the pathway to licensure, policy decision and use of group B Streptococcus vaccines for maternal immunization: considerations from World Health Organization consultations

scientific article

The way forward for tuberculosis vaccines

scientific article published on 01 March 2019

Tuberculosis contacts but not patients have higher gamma interferon responses to ESAT-6 than do community controls in The Gambia.

scientific article

Tuberculosis vaccines: Rising opportunities

Vaccine impact on antimicrobial resistance to inform Gavi, the Vaccine Alliance's 2018 Vaccine Investment Strategy: report from an expert survey

scientific article published on 24 September 2019

Vaccines for maternal immunization against Group B Streptococcus disease: WHO perspectives on case ascertainment and case definitions

scientific article published on 11 July 2019

WHO consultation on group B Streptococcus vaccine development: Report from a meeting held on 27-28 April 2016.

scientific article published on 22 December 2016

WHO preferred product characteristics for new vaccines against tuberculosis

scientific article published on 01 August 2018

WHO/IVI global stakeholder consultation on group A Streptococcus vaccine development: Report from a meeting held on 12-13 December 2016.

scientific article published on 26 February 2018

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