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List of works by Philip Bejon

10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens

scientific article published on 23 December 2015

A clinical trial of prime-boost immunisation with the candidate malaria vaccines RTS,S/AS02A and MVA-CS.

scientific article

A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine

scientific article

A framework for Controlled Human Infection Model (CHIM) studies in Malawi: Report of a Wellcome Trust workshop on CHIM in Low Income Countries held in Blantyre, Malawi

scientific article published on 24 August 2017

A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya

scientific article (publication date: 2014)

A micro-epidemiological analysis of febrile malaria in Coastal Kenya showing hotspots within hotspots

scientific article published on 24 April 2014

A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya

scientific article

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

scientific article

A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01 E on blood stage immunity in young Kenyan children.

scientific article

A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS,S/AS01E

scientific article

A threshold concentration of anti-merozoite antibodies is required for protection from clinical episodes of malaria

scientific article published on 22 June 2013

Acute seizures attributable to falciparum malaria in an endemic area on the Kenyan coast ⬇️

scientific article

Age, Spatial, and Temporal Variations in Hospital Admissions with Malaria in Kilifi County, Kenya: A 25-Year Longitudinal Observational Study

scientific article (publication date: June 2016)

Alternating vector immunizations encoding pre-erythrocytic malaria antigens enhance memory responses in a malaria endemic area

scientific article published in August 2006

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

scientific article published on 24 February 2021

An unsupported preference for intravenous antibiotics

scientific article published on 19 May 2015

Analysis of immunity to febrile malaria in children that distinguishes immunity from lack of exposure

scientific article published on 17 February 2009

Antigen-specific IL-2 secretion correlates with NK cell responses after immunization of Tanzanian children with the RTS,S/AS01 malaria vaccine

scientific article

Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care ⬇️

scientific article published on August 4, 2011

Author Correction: Investigating the drivers of the spatio-temporal patterns of genetic differences between Plasmodium falciparum malaria infections in Kilifi County, Kenya

scientific article published on 23 December 2020

Avidity of anti-circumsporozoite antibodies following vaccination with RTS,S/AS01E in young children

scientific article

B cell memory to 3 Plasmodium falciparum blood-stage antigens in a malaria-endemic area

scientific article published on 13 April 2005

Bayesian evaluation of the performance of three diagnostic tests for Plasmodium falciparum infection in a low-transmission setting in Kilifi County, Kenya

article

Bayesian evaluation of the performance of three diagnostic tests for Plasmodium falciparum infection in a low-transmission setting in Kilifi County, Kenya

scientific article published on 01 October 2019

Blood-stage challenge for malaria vaccine efficacy trials: a pilot study with discussion of safety and potential value.

scientific article

Calculation of liver-to-blood inocula, parasite growth rates, and preerythrocytic vaccine efficacy, from serial quantitative polymerase chain reaction studies of volunteers challenged with malaria sporozoites

scientific article

Changing Malaria Prevalence on the Kenyan Coast since 1974: Climate, Drugs and Vector Control

scientific article

Chronic Exposure to Plasmodium falciparum Is Associated with Phenotypic Evidence of B and T Cell Exhaustion ⬇️

scientific article published on December 21, 2012

Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01E and Protection against P falciparum Clinical Malaria ⬇️

scientific article published on October 6, 2011

Clearance of asymptomatic P. falciparum Infections Interacts with the number of clones to predict the risk of subsequent malaria in Kenyan children

scientific article

Clearing asymptomatic parasitaemia increases the specificity of the definition of mild febrile malaria

scientific article published on 15 August 2007

Comparison of allele frequencies of Plasmodium falciparum merozoite antigens in malaria infections sampled in different years in a Kenyan population

scientific article published on 6 May 2016

Comparison of modeling methods to determine liver-to-blood inocula and parasite multiplication rates during controlled human malaria infection ⬇️

scientific article published on 09 April 2013

Congenital microcephaly unrelated to flavivirus exposure in coastal Kenya

scientific article published on 15 November 2019

Correction: Quantitative PCR Evaluation of Cellular Immune Responses in Kenyan Children Vaccinated with a Candidate Malaria Vaccine.

scientific article

Correction: Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children.

scientific article

Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4 CD25 high T cells with susceptibility in Kenyans

scientific article published on 30 April 2008

Cost-effectiveness of oral versus intravenous antibiotics (OVIVA) in patients with bone and joint infection: evidence from a non-inferiority trial

scientific article published on 17 July 2019

Defining childhood severe falciparum malaria for intervention studies

scientific article

Defining clinical malaria: the specificity and incidence of endpoints from active and passive surveillance of children in rural Kenya

scientific article

Detecting Malaria Hotspots: A Comparison of Rapid Diagnostic Test, Microscopy, and Polymerase Chain Reaction

scientific article published on 7 July 2017

Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study

article by Angela Huttner et al published July 2018 in Lancet Infectious Diseases

Durable human memory T cells quantifiable by cultured enzyme-linked immunospot assays are induced by heterologous prime boost immunization and correlate with protection against malaria

scientific article published on November 2005

Dynamics and role of antibodies to Plasmodium falciparum merozoite antigens in children living in two settings with differing malaria transmission intensity

scientific article

Early gamma interferon and interleukin-2 responses to vaccination predict the late resting memory in malaria-naïve and malaria-exposed individuals

scientific article

Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children ⬇️

scientific article

Effect of transmission intensity on hotspots and micro-epidemiology of malaria in sub-Saharan Africa

scientific article

Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data

scientific article

Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5-17 months in Kenya and Tanzania: a randomised controlled trial

scientific article published on 13 January 2011

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

scientific article

Efficacy of text-message reminders on paediatric malaria treatment adherence and their post-treatment return to health facilities in Kenya: a randomized controlled trial

scientific article published on 25 January 2017

Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara

scientific article

Epidemiology of COVID-19 infections on routine polymerase chain reaction (PCR) and serology testing in Coastal Kenya

scientific article published on 23 February 2022

Estimating individual exposure to malaria using local prevalence of malaria infection in the field

scientific article

Ethical and scientific considerations on the establishment of a controlled human infection model for schistosomiasis in Uganda: report of a stakeholders’ meeting held in Entebbe, Uganda

scholarly article published 6 August 2018

Ethical and scientific considerations on the establishment of a controlled human infection model for schistosomiasis in Uganda: report of a stakeholders’ meeting held in Entebbe, Uganda

scientific article published on 18 April 2018

Ethical considerations in Controlled Human Malaria Infection studies in low resource settings: Experiences and perceptions of study participants in a malaria Challenge study in Kenya

scientific article published in 2018

Ethical considerations in Controlled Human Malaria Infection studies in low resource settings: Experiences and perceptions of study participants in a malaria Challenge study in Kenya.

scientific article published on 11 April 2018

Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection

scientific article

Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals

scientific article

Examining the human infectious reservoir for Plasmodium falciparum malaria in areas of differing transmission intensity

scientific article published on 26 October 2017

Extended follow-up following a phase 2b randomized trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya

scientific article

Feedback of research findings for vaccine trials: experiences from two malaria vaccine trials involving healthy children on the Kenyan Coast

scientific article published on 21 February 2013

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

scientific article

Four-year efficacy of RTS,S/AS01E and its interaction with malaria exposure

scientific article published on March 2013

Fraction of all hospital admissions and deaths attributable to malnutrition among children in rural Kenya

scientific article published on December 2008

Further analysis of correlates of protection from a phase 2a trial of the falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults

scientific article published in March 2010

Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort

scholarly article by Michelle K. Muthui et al published 5 April 2019 in Wellcome Open Research

Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort

scientific article published on 28 May 2019

Geographic-genetic analysis of Plasmodium falciparum parasite populations from surveys of primary school children in Western Kenya

scientific article published on 5 September 2017

HIV infection, malnutrition, and invasive bacterial infection among children with severe malaria

scientific article

Helminth infection and eosinophilia and the risk of Plasmodium falciparum malaria in 1- to 6-year-old children in a malaria endemic area

scientific article

Identifying children with excess malaria episodes after adjusting for variation in exposure: identification from a longitudinal study using statistical count models

scientific article published on 6 August 2015

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

scientific article

Immunogenicity of the candidate malaria vaccines FP9 and modified vaccinia virus Ankara encoding the pre-erythrocytic antigen ME-TRAP in 1-6 year old children in a malaria endemic area

scientific article published on 31 March 2006

Incorporating a quiz into informed consent processes: qualitative study of participants' reactions

scientific article

Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies

scientific article

Individual-level variations in malaria susceptibility and acquisition of clinical protection

Innate immune responses to human malaria: heterogeneous cytokine responses to blood-stage Plasmodium falciparum correlate with parasitological and clinical outcomes

scientific article published on October 2006

Interactions between age and ITN use determine the risk of febrile malaria in children

scientific article

Interferon-gamma polymorphisms and risk of iron deficiency and anaemia in Gambian children

scientific article published on 02 March 2020

Invasive Gram-negative bacilli are frequently resistant to standard antibiotics for children admitted to hospital in Kilifi, Kenya

scientific article published on 19 May 2005

Investigating the drivers of the spatio-temporal patterns of genetic differences between Plasmodium falciparum malaria infections in Kilifi County, Kenya

scientific article published on 13 December 2019

Lack of avidity maturation of merozoite antigen-specific antibodies with increasing exposure to Plasmodium falciparum amongst children and adults exposed to endemic malaria in Kenya

scientific article

Longitudinal analyses of immune responses to Plasmodium falciparum derived peptides corresponding to novel blood stage antigens in coastal Kenya

scientific article published on 26 February 2008

Malaria and Age Variably but Critically Control Hepcidin Throughout Childhood in Kenya

scientific article

Malaria hotspots defined by clinical malaria, asymptomatic carriage, PCR and vector numbers in a low transmission area on the Kenyan Coast

scientific article published on 14 April 2016

Malaria vaccine development: lessons from the field

scientific article published in August 2009

Malaria vaccines: past, present and future

scientific article published on 23 September 2013

Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children

scientific article

Micro-epidemiological structuring of Plasmodium falciparum parasite populations in regions with varying transmission intensities in Africa

scientific article (publication date: 14 February 2017)

Multiple functions of human T cells generated by experimental malaria challenge

scientific article published on November 2009

Natural diversity of the malaria vector Anopheles gambiae

scholarly article by Alistair Miles et al published 22 December 2016 in bioRxiv

Oral versus intravenous antibiotics for bone and joint infections: the OVIVA non-inferiority RCT

scientific article published on 01 August 2019

Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data

scientific article

Plasmodium falciparum malaria in children aged 0-2 years: the role of foetal haemoglobin and maternal antibodies to two asexual malaria vaccine candidates (MSP3 and GLURP).

scientific article

Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure

scientific article published on 23 August 2017

Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast

scientific article published on 06 August 2020

Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults

scientific article

Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome.

scientific article published on 17 July 2017

Quantitative PCR evaluation of cellular immune responses in Kenyan children vaccinated with a candidate malaria vaccine

scientific article published on 23 December 2009

Quantitative real-time polymerase chain reaction for malaria diagnosis and its use in malaria vaccine clinical trials.

scientific article published in July 2005

Randomized, double-blinded, controlled non-inferiority trials evaluating the immunogenicity and safety of fractional doses of Yellow Fever vaccines in Kenya and Uganda

scientific article published on 20 November 2019

Response to "Poor control vaccines in two randomised trials of malaria vaccine?".

scientific article published on 30 May 2009

Revealing the extent of the first wave of the COVID-19 pandemic in Kenya based on serological and PCR-test data

scientific article published in 2022

SARS-CoV-2 Omicron variant of concern in the Seychelles: Introduction and spread

scientific article published in 2023

Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants

scientific article published on 25 April 2016

Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults

scientific article

Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children

scientific article (publication date: 29 November 2010)

Safety profile of the viral vectors of attenuated fowlpox strain FP9 and modified vaccinia virus Ankara recombinant for either of 2 preerythrocytic malaria antigens, ME-TRAP or the circumsporozoite protein, in children and adults in Kenya

scientific article published on 14 March 2006

Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal.

scientific article

Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype

scientific article published on 2 May 2006

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

scientific article (publication date: 2011)

Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children

scientific article published on June 2016

Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa

scientific article published on 18 January 2018

Stable and unstable malaria hotspots in longitudinal cohort studies in Kenya

scientific article

Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS, S/AS01 malaria vaccine in African children

scientific article

Taking social relationships seriously: lessons learned from the informed consent practices of a vaccine trial on the Kenyan Coast

scientific article published on 24 March 2008

Temporal distribution and clinical characteristics of the Alpha, Delta and Omicron SARS-CoV-2 variants of concern in Laikipia, Kenya: institutional and community-based genomic surveillance

scientific article published in 2023

The effect of declining exposure on T cell-mediated immunity to Plasmodium falciparum - an epidemiological "natural experiment".

scientific article

The ferroportin Q248H mutation protects from anemia, but not malaria or bacteremia

scientific article published on 04 September 2019

The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum

scientific article published on September 2007

The prevalence of Plasmodium falciparum in sub-Saharan Africa since 1900.

scientific article published on 11 October 2017

The ratio of monocytes to lymphocytes in peripheral blood correlates with increased susceptibility to clinical malaria in Kenyan children

scientific article

The relationship between RTS,S vaccine-induced antibodies, CD4⁺ T cell responses and protection against Plasmodium falciparum infection

scientific article

Thick blood film examination for Plasmodium falciparum malaria has reduced sensitivity and underestimates parasite density

scientific article

Third human challenge trial conference, Oxford, United Kingdom, February 6-7, 2020, a meeting report

scientific article published on 03 June 2020

Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populations

scientific article

Trends in bednet ownership and usage, and the effect of bednets on malaria hospitalization in the Kilifi Health and Demographic Surveillance System (KHDSS): 2008-2015.

scientific article published on 15 November 2017

Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection

scientific article published on September 2005

Variation in the effectiveness of insecticide treated nets against malaria and outdoor biting by vectors in Kilifi, Kenya

scholarly article by Alice Kamau et al published 15 January 2018 in Wellcome Open Research

Variation in the effectiveness of insecticide treated nets against malaria and outdoor biting by vectors in Kilifi, Kenya

scientific article published on 30 March 2017

Variation in the effectiveness of insecticide treated nets against malaria and outdoor biting by vectors in Kilifi, Kenya

scientific article published on 01 January 2017

What you see is not what you get: implications of the brevity of antibody responses to malaria antigens and transmission heterogeneity in longitudinal studies of malaria immunity

scientific article published on 28 October 2009

Wind direction and proximity to larval sites determines malaria risk in Kilifi District in Kenya

scientific article published on 14 February 2012

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