Search filters

List of works by Jeanine Houwing-Duistermaat

A Genome-Wide Search for Genes Involved in Type 2 Diabetes in a Recently Genetically Isolated Population From the Netherlands

article

A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis

scientific article

A genome-wide linkage scan reveals CD53 as an important regulator of innate TNF-alpha levels

scientific article

A genome-wide search for linkage-disequilibrium with type 1 diabetes in a recent genetically isolated population from the Netherlands

scientific article published on March 2002

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function

scientific article

A mixture model with random-effects components for classifying sibling pairs.

scientific article published on 9 September 2011

A new score statistic to test for association given linkage in affected sibling pair-control designs

scientific article

A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism

A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer

scientific article

A retrospective likelihood approach for efficient integration of multiple omics factors in case-control association studies

scientific article published on 24 January 2015

A two-stage mixed-effects model approach for gene-set analyses in candidate gene studies

scientific article published on 14 October 2011

Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs

scientific article

Angiotensin-converting enzyme gene polymorphism and carotid artery wall thickness: a meta-analysis

scientific article

Are ATM mutations 7271T-->G and IVS10-6T-->G really high-risk breast cancer-susceptibility alleles?

scientific article published in February 2004

Assessment of global phase uncertainty in case-control studies

scientific article

Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study

scientific article

Association between an insulin-like growth factor I gene promoter polymorphism and bone mineral density in the elderly: the Rotterdam Study

scientific article

Author Correction: Tree mode of death and mortality risk factors across Amazon forests

scientific article published on 04 January 2021

CARD15 mutations in Dutch familial and sporadic inflammatory bowel disease and an overview of European studies

scientific article

CHEK2*1100delC homozygosity in the Netherlands--prevalence and risk of breast and lung cancer

scientific article published on 08 May 2013

Card15 and Crohn's disease: healthy homozygous carriers of the 3020insC frameshift mutation

scientific article published in March 2003

Chromosome 4q25, microsomal transfer protein gene, and human longevity: novel data and a meta-analysis of association studies

scientific article

Classification for Longevity Potential: The Use of Novel Biomarkers ⬇️

scientific article published on 28 October 2016

Cluster headache and the hypocretin receptor 2 reconsidered: a genetic association study and meta-analysis

scientific article published on 14 November 2014

Clustering of allergic outcomes within families and households in areas endemic for helminth infections

scientific article

Clustering of child mortality in a contemporary polygamous population in Africa

scientific article published in January 2012

Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps

scientific article

Combining evidence for association from transmission disequilibrium and case-control studies using single-nucleotide polymorphisms

scientific article published on 30 December 2005

Combining family and twin data in association studies to estimate the noninherited maternal antigens effect.

scientific article

Combining information from linkage and association mapping for next-generation sequencing longitudinal family data

scientific article

Comprehensive genetic analysis of seven large families with mismatch repair proficient colorectal cancer

article

Correction: A Candidate Gene Approach Identifies the TRAF1/C5 Region as a Risk Factor for Rheumatoid Arthritis

scientific article

Correction: The Effect of Three-Monthly Albendazole Treatment on Malarial Parasitemia and Allergy: A Household-Based Cluster-Randomized, Double-Blind, Placebo-Controlled Trial.

scientific article published on 9 September 2013

Correction: The complex genetics of gait speed: genome-wide meta-analysis approach

scientific article published on 7 July 2017

Correction: Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R.

scientific article published on 10 May 2012

Correlations between immune response and vascularization qRT-PCR gene expression clusters in squamous cervical cancer

scientific article

Dealing with high dimensionality for the identification of common and rare variants as main effects and for gene-environment interaction

scientific article published in January 2011

Decreased levels of bisecting GlcNAc glycoforms of IgG are associated with human longevity

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Delta-beta correlation as a candidate endophenotype of social anxiety: A two-generation family study ⬇️

scientific article

Detecting genetic variants for extreme aging using multiple data sources ⬇️

scientific article published on August 15, 2012

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

scientific article

Discussion on the paper ‘Statistical contributions to bioinformatics: Design, modelling, structure learning and integration’ by Jeffrey S. Morris and Veerabhadran Baladandayuthapani ⬇️

article

Does pathway analysis make it easier for common variants to tag rare ones?

scientific article

Doxycycline treatment of Brugia malayi-infected persons reduces microfilaremia and adverse reactions after diethylcarbamazine and albendazole treatment

scientific article

Dynamic changes in human-gut microbiome in relation to a placebo-controlled anthelminthic trial in Indonesia ⬇️

scholarly article by Ivonne Martin et al published August 2018 in PLoS Neglected Tropical Diseases

Early cognitive decline is associated with prion protein codon 129 polymorphism

scientific article (publication date: August 2003)

Effect of Anthelmintic Treatment on Insulin Resistance: A Cluster-Randomized Placebo-Controlled Trial in Indonesia

scientific article

Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort

scientific article published on 20 October 2009

Erratum to: Making sense of big data in health research: towards an EU action plan

scientific article

Estimation of genetic effects in multiple cases family studies using penalized maximum likelihood methodology ⬇️

scientific article published on September 18, 2012

Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women

scientific article published in September 2006

Evaluation of O2PLS in Omics data integration ⬇️

scientific article

Evaluation of regression methods when immunological measurements are constrained by detection limits

scientific article

Evidence for novel loci for late-onset Parkinson’s disease in a genetic isolate from the Netherlands

article

Familial longevity is associated with decreased thyroid function

scientific article published on 25 August 2010

Family score as an indicator of genetic risk of primary open-angle glaucoma

scientific article published on December 2002

From sporadic atypical nevi to familial melanoma: Risk analysis for melanoma in sporadic atypical nevus patients

Gene analysis for longitudinal family data using random-effects models

scientific article

Gene coexpression network analysis for family studies based on a meta-analytic approach

scientific article

Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways

scientific article

Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function

scientific article

Generalizing Terwilliger's likelihood approach: a new score statistic to test for genetic association

scientific article

Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study.

scientific article

Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis

scientific article published on 5 October 2012

Genetic, household and spatial clustering of leprosy on an island in Indonesia: a population-based study

scientific article

Genome-wide analysis in multiple-case families: assessing the relationship between triglyceride and methylation

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

scientific article

Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity

scientific article

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

scientific article

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

scientific article published on 06 February 2013

Genome-wide linkage scan in Dutch hereditary non-BRCA1/2 breast cancer families identifies 9q21-22 as a putative breast cancer susceptibility locus

scientific article published in November 2008

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

scientific article published on 21 June 2016

Genotype-Based Score Test for Association Testing in Families

scientific article

Global tests for linkage

scientific article published on February 2009

Helminth infections and type 2 diabetes: a cluster-randomized placebo controlled SUGARSPIN trial in Nangapanda, Flores, Indonesia

scientific article

High-Resolution Hydrogen–Deuterium Protection Factors from Sparse Mass Spectrometry Data Validated by Nuclear Magnetic Resonance Measurements

scientific article published in 2022

High-throughput characterization of 10 new minor histocompatibility antigens by whole genome association scanning

scientific article published on 9 November 2010

How to deal with the early GWAS data when imputing and combining different arrays is necessary

scientific article

How to quantify information loss due to phase ambiguity in haplotype case-control studies

scientific article published on 30 December 2005

Human Plasma N-glycosylation as Analyzed by Matrix-Assisted Laser Desorption/Ionization-Fourier Transform Ion Cyclotron Resonance-MS Associates with Markers of Inflammation and Metabolic Health ⬇️

scientific article

Hydrogen exchange protection factors can be extracted from sparse HDX-MS data

IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study

scientific article

Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

scientific article published on 11 March 2008

Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis.

scientific article published on 16 August 2013

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study ⬇️

scientific article published on July 3, 2012

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

Identifying rare variants from exome scans: the GAW17 experience

scientific article

Improving stability of prediction models based on correlated omics data by using network approaches ⬇️

scientific article published on 20 February 2018

Influence of genotyping error in linkage mapping for complex traits--an analytic study

scientific article

Integrating omics datasets with the OmicsPLS package

scholarly article by Said El Bouhaddani published in October 2018

Integration of gene ontology pathways with North American Rheumatoid Arthritis Consortium genome-wide association data via linear modeling

scientific article

Interleukin-1 gene cluster variants with innate cytokine production profiles and osteoarthritis in subjects from the Genetics, Osteoarthritis and Progression Study

scientific article

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

scientific article

Lipid metabolism in long-lived families: the Leiden Longevity Study

scientific article

Lipidomics of familial longevity

scientific article published on 02 April 2013

Lipoprotein particle profiles mark familial and sporadic human longevity

scientific article

Liver X receptor alpha associates with human life span

scientific article published on 01 April 2007

Locally weighted transmission/disequilibrium test for genetic association analysis

scientific article published on 30 December 2005

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

scientific article

Longevity around the turn of the 20th century: life-long sustained survival advantage for parents of today's nonagenarians ⬇️

scientific article published on 27 March 2018

MUTYH gene variants and breast cancer in a Dutch case–control study

scientific article

Making sense of big data in health research: Towards an EU action plan

scientific article

Maternal and child cytokine relationship in early life is not altered by cytokine gene polymorphisms. ⬇️

scientific article

Metabolic effects of a 13-weeks lifestyle intervention in older adults: The Growing Old Together Study

scientific article published on 25 January 2016

Methods to test for association between a disease and a multi-allelic marker applied to a candidate region

scientific article published on 30 December 2005

Model selection based on logistic regression in a highly correlated candidate gene region

scientific article

Modeling the effect of an associated single-nucleotide polymorphism in linkage studies

scientific article published on 30 December 2005

Monoamine Oxidase A (MAOA) Gene and Personality Traits from Late Adolescence through Early Adulthood: A Latent Variable Investigation

scientific article published on 11 October 2017

New score tests for age-at-onset linkage analysis in general pedigrees

scientific article

Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data

scientific article

Pathway analysis for family data using nested random-effects models

scientific article

Pathway analysis using genome-wide association study data for coronary restenosis--a potential role for the PARVB gene

scientific article

Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health.

scientific article published on 23 February 2011

Polymorphisms in PARP, IL1B, IL4, IL10, C1INH, DEFB1, and DEFA4 in meningococcal disease in three populations

scientific article

Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study

scientific article

Polymorphisms in the prion protein gene and in the doppel gene increase susceptibility for Creutzfeldt-Jakob disease

scientific article published in May 2004

Probabilistic partial least squares model: Identifiability, estimation and application ⬇️

article by Said el Bouhaddani et al published September 2018 in Journal of Multivariate Analysis

Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated pr

scientific article

Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis.

scientific article published on April 2009

Relationship between genome and epigenome--challenges and requirements for future research

scientific article published on 18 June 2014

Reliability of cluster results for different types of time adjustments in complex disease research

scientific article published in January 2008

Secondary phenotype analysis in ascertained family designs: application to the Leiden longevity study ⬇️

scientific article

Sequential double cross-validation for assessment of added predictive ability in high-dimensional omic applications ⬇️

Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility.

scientific article

Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health

scientific article published on 26 September 2017

Survival analysis with delayed entry in selected families with application to human longevity ⬇️

scientific article

Systematic testing of literature reported genetic variation associated with coronary restenosis: results of the GENDER Study

scientific article

Targeted biomarker discovery by high throughput glycosylation profiling of human plasma alpha1-antitrypsin and immunoglobulin A.

scientific article

Testing for genetic association in the presence of linkage and gene-covariate interactions

scientific article published on February 2010

Testing for genetic association taking into account phenotypic information of relatives

scientific article

The ACPA recognition profile and subgrouping of ACPA-positive RA patients

scientific article published on 13 October 2011

The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

scientific article published on 14 May 2013

The Genome of the Netherlands: design, and project goals

scientific article (publication date: February 2014)

The Leiden Family Lab study on Social Anxiety Disorder: A multiplex, multigenerational family study on neurocognitive endophenotypes ⬇️

scientific article published on 26 April 2018

The MC1R Gene and Youthful Looks

scientific article published on 27 April 2016

The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases.

scientific article published on 10 May 2009

The complex genetics of gait speed: genome-wide meta-analysis approach

scientific article published on 10 January 2017

The effect of three-monthly albendazole treatment on malarial parasitemia and allergy: a household-based cluster-randomized, double-blind, placebo-controlled trial

scientific article

The impact of low-frequency and rare variants on lipid levels

scientific article published on 11 May 2015

The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study

scientific article published on 12 April 2004

The transcriptional landscape of age in human peripheral blood

scientific article

Transcriptional profiling of human familial longevity indicates a role for ASF1A and IL7R

scientific article (publication date: 2012)

Tree mode of death and mortality risk factors across Amazon forests

scientific article published on 09 November 2020

Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2.

scientific article published on 29 January 2016

Utility of whole-genome sequence data for across-breed genomic prediction. ⬇️

scientific article

Vitamin D receptor polymorphisms and growth until adulthood after very premature birth

scientific article published on 28 July 2015

Weighted statistics for aggregation and linkage analysis of human longevity in selected families: the Leiden Longevity Study.

scientific article published in January 2009

Paulina is supported by:

About Paulina

Help