List of works - Thomas Szyperski

1H, 13C, and 15N resonance assignments and secondary structure of the PWI domain from SRm160 using reduced dimensionality NMR

scientific article (publication date: March 2002)

A community resource of experimental data for NMR / X-ray crystal structure pairs.

scientific article

A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants

scientific article

Accurate de novo design of hyperstable constrained peptides

scientific article

Accurate protein structure modeling using sparse NMR data and homologous structure information

scientific article

Advances in protein NMR provided by the NIGMS Protein Structure Initiative: impact on drug discovery.

scientific article

An integrated platform for automated analysis of protein NMR structures.

scientific article

Backbone 1H, 15N and 13C assignments for the 21 kDa Caenorhabditis elegans homologue of "brain-specific" protein

scientific article

Central carbon metabolism of Saccharomyces cerevisiae explored by biosynthetic fractional (13)C labeling of common amino acids

scientific article

Combined NMR-observation of cold denaturation in supercooled water and heat denaturation enables accurate measurement of deltaC(p) of protein unfolding

scientific article

Computational de novo design of a four-helix bundle protein--DND_4HB.

scientific article

Consistent blind protein structure generation from NMR chemical shift data

scientific article

G-matrix Fourier transform NOESY-based protocol for high-quality protein structure determination.

scientific article

GFT NMR, a new approach to rapidly obtain precise high-dimensional NMR spectral information.

scientific article

High-quality NMR structure of human anti-apoptotic protein domain Mcl-1(171-327) for cancer drug design

scientific article

Increasing Sequence Diversity with Flexible Backbone Protein Design: The Complete Redesign of a Protein Hydrophobic Core ⬇️

scientific article published on May 24, 2012

Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer ⬇️

scientific article published on December 15, 2011

NMR Structure and Dynamics of the Engineered Fluorescein-Binding Lipocalin FluA Reveal Rigidification of β-Barrel and Variable Loops upon Enthalpy-Driven Ligand Binding

scientific article

NMR data collection and analysis protocol for high-throughput protein structure determination

scientific article

NMR determination of the secondary structure and the three-dimensional polypeptide backbone fold of the human sterol carrier protein 2

scientific article

NMR solution structure of Thermotoga maritima protein TM1509 reveals a Zn-metalloprotease-like tertiary structure

scientific article published on 01 January 2005

NMR solution structure of the pathogenesis-related protein P14a

scientific article

NMR structure determination for larger proteins using backbone-only data

scientific article

NMR structure of lipoprotein YxeF from Bacillus subtilis reveals a calycin fold and distant homology with the lipocalin Blc from Escherichia coli

scientific article

NMR structure of protein Cgl2762 from Corynebacterium glutamicum implicated in DNA transposition reveals a helix-turn-helix motif attached to a flexibly disordered leucine zipper

scientific article

NMR structure of protein PA2021 from Pseudomonas aeruginosa

scientific article published on 01 November 2006

NMR structure of protein YvyC fromBacillus subtilisreveals unexpected structural similarity between two PFAM families

scientific article

NMR structure of protein yjbR from Escherichia coli reveals 'double-wing' DNA binding motif

scientific article

NMR structure of the J-domain and the Gly/Phe-rich region of the Escherichia coli DnaJ chaperone

scientific article

NMR structure of the chimeric hybrid duplex r(gcaguggc).r(gcca)d(CTGC) comprising the tRNA-DNA junction formed during initiation of HIV-1 reverse transcription

scientific article

NMR structure of the peptidyl-tRNA hydrolase domain from Pseudomonas syringae expands the structural coverage of the hydrolysis domains of class 1 peptide chain release factors

scientific article

NMR structure of the sterol carrier protein-2: implications for the biological role

scientific article

NMR-based structural biology of proteins in supercooled water ⬇️

scientific article published on May 1, 2011

Nuclear magnetic resonance solution structure of hirudin(1-51) and comparison with corresponding three-dimensional structures determined using the complete 65-residue hirudin polypeptide chain

scientific article published on December 20, 1992

Protein chaperones Q8ZP25_SALTY from Salmonella typhimurium and HYAE_ECOLI from Escherichia coli exhibit thioredoxin-like structures despite lack of canonical thioredoxin active site sequence motif

scientific article

Protein dynamics in supercooled water: the search for slow motional modes

scientific article

Rapid NMR data collection

scientific article

Resonance assignments for the hypothetical protein yggU from Escherichia coli

scientific article

Solution NMR Experiment for Measurement of (15)N-(1)H Residual Dipolar Couplings in Large Proteins and Supramolecular Complexes.

scientific article

Solution NMR Structure of Yeast Succinate Dehydrogenase Flavinylation Factor Sdh5 Reveals a Putative Sdh1 Binding Site

scientific article

Solution NMR structure of MED25(391–543) comprising the activator-interacting domain (ACID) of human mediator subunit 25

scientific article

Solution NMR structures of proteins VPA0419 fromVibrio parahaemolyticusand yiiS fromShigella flexneriprovide structural coverage for protein domain family PFAM 04175

scientific article

Structural and Functional Characterization of DUF1471 Domains of Salmonella Proteins SrfN, YdgH/SssB, and YahO

scientific article

Structure comparison of human glioma pathogenesis-related protein GliPR and the plant pathogenesis-related protein P14a indicates a functional link between the human immune system and a plant defense system ⬇️

scientific article published on March 3, 1998

The NMR solution structure of the 30S ribosomal protein S27e encoded in gene RS27_ARCFU of Archaeoglobus fulgidis reveals a novel protein fold

scientific article (publication date: May 2004)

The NMR structure of the pulmonary surfactant-associated polypeptide SP-C in an apolar solvent contains a valyl-rich alpha-helix

scientific article

The phosphoenolpyruvate carboxykinase also catalyzes C3 carboxylation at the interface of glycolysis and the TCA cycle of Bacillus subtilis

scientific article

Unique opportunities for NMR methods in structural genomics.

scientific article

List of works by Thomas Szyperski

1H, 13C, and 15N resonance assignments and secondary structure of the PWI domain from SRm160 using reduced dimensionality NMR

A community resource of experimental data for NMR / X-ray crystal structure pairs.

A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants

Accurate de novo design of hyperstable constrained peptides

Accurate protein structure modeling using sparse NMR data and homologous structure information

Advances in protein NMR provided by the NIGMS Protein Structure Initiative: impact on drug discovery.

An integrated platform for automated analysis of protein NMR structures.

Backbone 1H, 15N and 13C assignments for the 21 kDa Caenorhabditis elegans homologue of "brain-specific" protein

Central carbon metabolism of Saccharomyces cerevisiae explored by biosynthetic fractional (13)C labeling of common amino acids

Combined NMR-observation of cold denaturation in supercooled water and heat denaturation enables accurate measurement of deltaC(p) of protein unfolding

Computational de novo design of a four-helix bundle protein--DND_4HB.

Consistent blind protein structure generation from NMR chemical shift data

G-matrix Fourier transform NOESY-based protocol for high-quality protein structure determination.

GFT NMR, a new approach to rapidly obtain precise high-dimensional NMR spectral information.

High-quality NMR structure of human anti-apoptotic protein domain Mcl-1(171-327) for cancer drug design

Increasing Sequence Diversity with Flexible Backbone Protein Design: The Complete Redesign of a Protein Hydrophobic Core ⬇️

Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer ⬇️

NMR Structure and Dynamics of the Engineered Fluorescein-Binding Lipocalin FluA Reveal Rigidification of β-Barrel and Variable Loops upon Enthalpy-Driven Ligand Binding

NMR data collection and analysis protocol for high-throughput protein structure determination

NMR determination of the secondary structure and the three-dimensional polypeptide backbone fold of the human sterol carrier protein 2

NMR solution structure of Thermotoga maritima protein TM1509 reveals a Zn-metalloprotease-like tertiary structure

NMR solution structure of the pathogenesis-related protein P14a

NMR structure determination for larger proteins using backbone-only data

NMR structure of lipoprotein YxeF from Bacillus subtilis reveals a calycin fold and distant homology with the lipocalin Blc from Escherichia coli

NMR structure of protein Cgl2762 from Corynebacterium glutamicum implicated in DNA transposition reveals a helix-turn-helix motif attached to a flexibly disordered leucine zipper

NMR structure of protein PA2021 from Pseudomonas aeruginosa

NMR structure of protein YvyC fromBacillus subtilisreveals unexpected structural similarity between two PFAM families

NMR structure of protein yjbR from Escherichia coli reveals 'double-wing' DNA binding motif

NMR structure of the J-domain and the Gly/Phe-rich region of the Escherichia coli DnaJ chaperone

NMR structure of the chimeric hybrid duplex r(gcaguggc).r(gcca)d(CTGC) comprising the tRNA-DNA junction formed during initiation of HIV-1 reverse transcription

NMR structure of the peptidyl-tRNA hydrolase domain from Pseudomonas syringae expands the structural coverage of the hydrolysis domains of class 1 peptide chain release factors

NMR structure of the sterol carrier protein-2: implications for the biological role

NMR-based structural biology of proteins in supercooled water ⬇️

Nuclear magnetic resonance solution structure of hirudin(1-51) and comparison with corresponding three-dimensional structures determined using the complete 65-residue hirudin polypeptide chain

Protein chaperones Q8ZP25_SALTY from Salmonella typhimurium and HYAE_ECOLI from Escherichia coli exhibit thioredoxin-like structures despite lack of canonical thioredoxin active site sequence motif

Protein dynamics in supercooled water: the search for slow motional modes

Rapid NMR data collection

Resonance assignments for the hypothetical protein yggU from Escherichia coli

Solution NMR Experiment for Measurement of (15)N-(1)H Residual Dipolar Couplings in Large Proteins and Supramolecular Complexes.

Solution NMR Structure of Yeast Succinate Dehydrogenase Flavinylation Factor Sdh5 Reveals a Putative Sdh1 Binding Site

Solution NMR structure of MED25(391–543) comprising the activator-interacting domain (ACID) of human mediator subunit 25

Solution NMR structures of proteins VPA0419 fromVibrio parahaemolyticusand yiiS fromShigella flexneriprovide structural coverage for protein domain family PFAM 04175

Structural and Functional Characterization of DUF1471 Domains of Salmonella Proteins SrfN, YdgH/SssB, and YahO

Structure comparison of human glioma pathogenesis-related protein GliPR and the plant pathogenesis-related protein P14a indicates a functional link between the human immune system and a plant defense system ⬇️

The NMR solution structure of the 30S ribosomal protein S27e encoded in gene RS27_ARCFU of Archaeoglobus fulgidis reveals a novel protein fold

The NMR structure of the pulmonary surfactant-associated polypeptide SP-C in an apolar solvent contains a valyl-rich alpha-helix

The phosphoenolpyruvate carboxykinase also catalyzes C3 carboxylation at the interface of glycolysis and the TCA cycle of Bacillus subtilis

Unique opportunities for NMR methods in structural genomics.