List of works by Rachelle Gaudet

A Partial Calcium-Free Linker Confers Flexibility to Inner-Ear Protocadherin-15.

scientific article published on 20 February 2017

A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin

scientific article

A primer on ankyrin repeat function in TRP channels and beyond

scientific article published on 26 March 2008

A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases.

scientific article

Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2

scientific article

Antigen processing and presentation: TAPping into ABC transporters

scientific article published on February 2009

Antiparallel protocadherin homodimers use distinct affinity- and specificity mediating regions in cadherin repeats 1-4

Antiparallel protocadherin homodimers use distinct affinity- and specificity-mediating regions in cadherin repeats 1-4

scientific article (publication date: 29 July 2016)

Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels

article

Characterization and structural studies of the Plasmodium falciparum ubiquitin and Nedd8 hydrolase UCHL3

scientific article

Conserved methionine dictates substrate preference in Nramp-family divalent metal transporters

scientific article published on 29 August 2016

Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin

scientific article

D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domain

scientific article

Data publication with the structural biology data grid supports live analysis

scientific article

Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain

scientific article

Distinct properties of Ca 2+ –calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel

scientific article

Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter

scientific journal article

Divide and conquer: high resolution structural information on TRP channel fragments

scientific article published on March 2009

Dominant mutations in the cation channel gene transient receptor potential vanilloid 4 cause an unusual spectrum of neuropathies

scientific article

Exome sequencing identifies a novel TRPV4 mutation in a CMT2C family

scientific article

Functionally important interactions between the nucleotide-binding domains of an antigenic peptide transporter

scientific article published on 2 May 2008

Genome-wide detection and characterization of positive selection in human populations

scientific article

High-resolution views of TRPV1 and their implications for the TRP channel superfamily

scientific article published on January 2014

How the TRPA1 receptor transmits painful stimuli: Inner workings revealed by electron cryomicroscopy

scientific article

Identification of a structural motif that confers specific interaction with the WD40 repeat domain of Arabidopsis COP1.

scientific article

Identification of domain boundaries within the N-termini of TAP1 and TAP2 and their importance in tapasin binding and tapasin-mediated increase in peptide loading of MHC class I.

scientific article published on October 2005

Insights into the molecular foundations of electrical excitation

scientific article published on January 2015

Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis

scientific article published on 20 August 2019

Mechanics and pharmacology of substrate selection and transport by eukaryotic ABC exporters

scientific article published on 26 August 2019

Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter

scientific article

Molecular Mechanics of Tip-Link Cadherins

Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C

scientific article

Noddy, a mouse harboring a missense mutation in protocadherin-15, reveals the impact of disrupting a critical interaction site between tip-link cadherins in inner ear hair cells

scientific article published on March 2013

Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli.

scientific article published on 20 May 2013

Proton co-transport and voltage dependence enforce unidirectional metal transport in an Nramp transporter

Sorting out a promiscuous superfamily: towards cadherin connectomics

scientific article published on 30 April 2014

Structural Analyses of the Ankyrin Repeat Domain of TRPV6 and Related TRPV Ion Channels † , ‡

scientific article

Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel

scientific article

Structural and functional analysis of human cytomegalovirus US3 protein

scientific article published on January 2004

Structural aspects of heterotrimeric G-protein signaling

scientific article published on August 1997

Structural biology of TRP channels

Structural characterization of the late competence protein ComFB from Bacillus subtilis

scientific article

Structural determinants of cadherin-23 function in hearing and deafness

scientific article

Structure and Sequence Analyses of Clustered Protocadherins Reveal Antiparallel Interactions that Mediate Homophilic Specificity

scientific article (publication date: 3 November 2015)

Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction

scientific article

Structure of a herpesvirus-encoded cysteine protease reveals a unique class of deubiquitinating enzymes

scientific article

Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing

scientific article

Structure of the N-terminal Ankyrin Repeat Domain of the TRPV2 Ion Channel

scientific article published in Journal of Biological Chemistry

Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate

scientific article

Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter

Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter

scientific article published on 04 February 2019

TRP channels entering the structural era.

scientific article published on 05 June 2008

The ABCs of trans(porter) inhibition

The Touching Tail of a Mechanotransduction Channel

scientific article published in September 2015

The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity

scientific article

The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter.

scientific article published on 27 January 2009

The role of the N terminus and transmembrane domain of TRPM8 in channel localization and tetramerization

scientific article

Transmembrane helix 6b links proton and metal release pathways and drives conformational change in an Nramp-family transition metal transporter

scientific article published on 27 December 2019

Ubiquitylation of the transducin betagamma subunit complex. Regulation by phosducin

scientific article (publication date: 15 November 2002)

Unique structural features in an Nramp metal transporter impart substrate-specific proton cotransport and a kinetic bias to favor import

scientific article published on 16 October 2019

Virus subversion of immunity: a structural perspective

scientific article

What do we know about the transient receptor potential vanilloid 2 (TRPV2) ion channel?

scientific article published on 28 May 2013